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The map label for this gene is expZ [H]

Identifier: 116491834

GI number: 116491834

Start: 17257

End: 18741

Strand: Direct

Name: expZ [H]

Synonym: PEPE_0016

Alternate gene names: 116491834

Gene position: 17257-18741 (Clockwise)

Preceding gene: 116491833

Following gene: 116491835

Centisome position: 0.94

GC content: 38.65

Gene sequence:

>1485_bases
ATGGGAATAATACAATTAAAAAACGTAAGCTTTAGCTACGATAACCAAATAAAACCGGTTTTTGACCAAGTAGCGTTGGA
AATCGATGCGAGCTGGAAATTAGGTCTGGTTGGCAGAAATGGGCGTGGTAAAACAACGCTGATGAAGATTTTGCAGAATC
AGGTTGAATATGAGGGGAAAGTGGAAACCAACCTGAAGTTCAATTATTTTCCAGCTAAAATTACTGAACCACAGGATTCG
GTGCGAATGATCCTGATGAAAATTACTGGTCGCGATTACTCTGATTTCTGGGAGGTTGAGCGAGAATTAGACCAAATTGG
ACTTGCTGAAGAAATTTTAGAGCAGACTTATGCATCACTAAGTCCGGGGCAACAAACTAAAGCCCTTTTAGCAGCCATGT
TTGCAGATCAAAATTCATTTCAATTGATTGATGAACCAACGAATCATTTGGATGCTGCTGGCCGCGACCTTTTAGCTAAA
TATTTAAAACAAAAACAAGGATACATTGTGGTTAGTCATGATCGTTACTTTTTAAATCAAGTTATTGATCATGTTATTTC
AATTGATCGTGCTCAAATTAGTAGCTTTAAGGGGAATTATGAAACCTGGGCAGCTGAACGTGCCAATGCGGATGAACGTG
AAATCAGTTTGAATGCCACGATGAAAAAAGATATAAAAAAATTAGAACAGGCCACGCGCCAAAAGCAAGAGTGGTCCCGA
GCAACGGAACGTAAAAAAGCTGGCGCTCCGGATAAGGGTTTTGTAGGTCATAAAGCAGCTAAAGTGATGAGCAAAGCCTT
GAATATTCGGGATCGGGCTGAGAAAAAATTAACAGATAAGAAACAGTTACTAAAGAATATTGAAATTCAGGATGAACTTC
AATTGAATTATCAACCGTATCTTGGACCCCAAAACAATGCTTTACTAGAAGCGGATAGTTTAGTTTTACAACGAGCTGGA
AAACTATTAAATCAGCCACTTAATTTTGAACTAAAGAAGAATGAGCGGATGGTTATTCAAGGCGAAAATGGTTCTGGAAA
ATCAACTTTAATTAAGGCAATGTTGGGACAAAATGAACTAATTGCTGAAGGTAATCTAAAAATACGCGAAAATTTACGAA
TATCATATTTACCACAGGACTTTGACCAACTCCAAGGCACACTAGAACAGTTTGCTGCCGAAAAGGAGGTTGAAGTTCAG
GACTTGCTGGCAATGCTGAGAAAACTGGGTTTTGAACGTACGATGTTTGATTATCGAATTGAGCAGATGAGTATGGGACA
GAAGAGAAAAGTTGCCTTAGCTCGGTCGCTGTGTGAAGAAGCCAATCTATATATTTGGGATGAACCCCTAAACTACCTAG
ATGTAATCACACGGGAACAAATTCAAAATTTAGTTTTGAAGTTCAAGCCCACCTTATTAGTGGTGGAACATGATCGAGAG
TTTGTCCAGAAAATTGCAACGCAGACCGTTAACTTAAAAAAATAA

Upstream 100 bases:

>100_bases
TTTTTATTGGTATTATGCACTTTGTATTGCATCAGGCCTGCACACCTGGTGCTTTTTTATGCCTTAAAACGAACTACTCC
TCGAAAGAGAGGAGACATAA

Downstream 100 bases:

>100_bases
GCAAATAATTTTGACACGGTGTCACTTTGTGCTATTCTAGCATTGTTGACACGGTGTCATTTTTATTTTAAGGAGGTGGA
GGAGTGGCTTCAGATGTTTT

Product: ABC transporter ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 494; Mature: 493

Protein sequence:

>494_residues
MGIIQLKNVSFSYDNQIKPVFDQVALEIDASWKLGLVGRNGRGKTTLMKILQNQVEYEGKVETNLKFNYFPAKITEPQDS
VRMILMKITGRDYSDFWEVERELDQIGLAEEILEQTYASLSPGQQTKALLAAMFADQNSFQLIDEPTNHLDAAGRDLLAK
YLKQKQGYIVVSHDRYFLNQVIDHVISIDRAQISSFKGNYETWAAERANADEREISLNATMKKDIKKLEQATRQKQEWSR
ATERKKAGAPDKGFVGHKAAKVMSKALNIRDRAEKKLTDKKQLLKNIEIQDELQLNYQPYLGPQNNALLEADSLVLQRAG
KLLNQPLNFELKKNERMVIQGENGSGKSTLIKAMLGQNELIAEGNLKIRENLRISYLPQDFDQLQGTLEQFAAEKEVEVQ
DLLAMLRKLGFERTMFDYRIEQMSMGQKRKVALARSLCEEANLYIWDEPLNYLDVITREQIQNLVLKFKPTLLVVEHDRE
FVQKIATQTVNLKK

Sequences:

>Translated_494_residues
MGIIQLKNVSFSYDNQIKPVFDQVALEIDASWKLGLVGRNGRGKTTLMKILQNQVEYEGKVETNLKFNYFPAKITEPQDS
VRMILMKITGRDYSDFWEVERELDQIGLAEEILEQTYASLSPGQQTKALLAAMFADQNSFQLIDEPTNHLDAAGRDLLAK
YLKQKQGYIVVSHDRYFLNQVIDHVISIDRAQISSFKGNYETWAAERANADEREISLNATMKKDIKKLEQATRQKQEWSR
ATERKKAGAPDKGFVGHKAAKVMSKALNIRDRAEKKLTDKKQLLKNIEIQDELQLNYQPYLGPQNNALLEADSLVLQRAG
KLLNQPLNFELKKNERMVIQGENGSGKSTLIKAMLGQNELIAEGNLKIRENLRISYLPQDFDQLQGTLEQFAAEKEVEVQ
DLLAMLRKLGFERTMFDYRIEQMSMGQKRKVALARSLCEEANLYIWDEPLNYLDVITREQIQNLVLKFKPTLLVVEHDRE
FVQKIATQTVNLKK
>Mature_493_residues
GIIQLKNVSFSYDNQIKPVFDQVALEIDASWKLGLVGRNGRGKTTLMKILQNQVEYEGKVETNLKFNYFPAKITEPQDSV
RMILMKITGRDYSDFWEVERELDQIGLAEEILEQTYASLSPGQQTKALLAAMFADQNSFQLIDEPTNHLDAAGRDLLAKY
LKQKQGYIVVSHDRYFLNQVIDHVISIDRAQISSFKGNYETWAAERANADEREISLNATMKKDIKKLEQATRQKQEWSRA
TERKKAGAPDKGFVGHKAAKVMSKALNIRDRAEKKLTDKKQLLKNIEIQDELQLNYQPYLGPQNNALLEADSLVLQRAGK
LLNQPLNFELKKNERMVIQGENGSGKSTLIKAMLGQNELIAEGNLKIRENLRISYLPQDFDQLQGTLEQFAAEKEVEVQD
LLAMLRKLGFERTMFDYRIEQMSMGQKRKVALARSLCEEANLYIWDEPLNYLDVITREQIQNLVLKFKPTLLVVEHDREF
VQKIATQTVNLKK

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=538, Percent_Identity=24.1635687732342, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI27881506, Length=523, Percent_Identity=22.9445506692161, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI10947137, Length=523, Percent_Identity=22.9445506692161, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI108773784, Length=158, Percent_Identity=31.6455696202532, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI108773782, Length=158, Percent_Identity=31.6455696202532, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI69354671, Length=191, Percent_Identity=29.3193717277487, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI10947135, Length=191, Percent_Identity=29.3193717277487, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1787041, Length=544, Percent_Identity=26.8382352941176, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI2367384, Length=525, Percent_Identity=25.3333333333333, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI1787182, Length=537, Percent_Identity=26.4432029795158, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1789751, Length=518, Percent_Identity=23.9382239382239, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1789962, Length=194, Percent_Identity=25.7731958762887, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788165, Length=166, Percent_Identity=29.5180722891566, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790467, Length=193, Percent_Identity=26.4248704663212, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17559834, Length=540, Percent_Identity=24.4444444444444, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17553372, Length=502, Percent_Identity=25.4980079681275, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17555318, Length=203, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17555800, Length=170, Percent_Identity=31.1764705882353, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320874, Length=533, Percent_Identity=24.765478424015, Blast_Score=101, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6321121, Length=219, Percent_Identity=30.1369863013699, Blast_Score=91, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6324314, Length=177, Percent_Identity=29.3785310734463, Blast_Score=84, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6325030, Length=227, Percent_Identity=28.1938325991189, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6323278, Length=211, Percent_Identity=27.9620853080569, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24666836, Length=540, Percent_Identity=24.0740740740741, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24642252, Length=535, Percent_Identity=22.803738317757, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI18859989, Length=535, Percent_Identity=22.803738317757, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24641342, Length=211, Percent_Identity=26.5402843601896, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24661270, Length=154, Percent_Identity=31.1688311688312, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21355589, Length=154, Percent_Identity=31.1688311688312, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 56737; Mature: 56606

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIIQLKNVSFSYDNQIKPVFDQVALEIDASWKLGLVGRNGRGKTTLMKILQNQVEYEGK
CCEEEEECCCCCCCCCCHHHHHHHHEEECCCEEEEEEECCCCCHHHHHHHHHHHHCCCCC
VETNLKFNYFPAKITEPQDSVRMILMKITGRDYSDFWEVERELDQIGLAEEILEQTYASL
EECCEEEEEECCCCCCCHHHHHEEEHEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHC
SPGQQTKALLAAMFADQNSFQLIDEPTNHLDAAGRDLLAKYLKQKQGYIVVSHDRYFLNQ
CCCHHHHHHHHHHHCCCCCCEECCCCCHHHHHCCHHHHHHHHHCCCCEEEEECCHHHHHH
VIDHVISIDRAQISSFKGNYETWAAERANADEREISLNATMKKDIKKLEQATRQKQEWSR
HHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHH
ATERKKAGAPDKGFVGHKAAKVMSKALNIRDRAEKKLTDKKQLLKNIEIQDELQLNYQPY
HHHHHHCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCC
LGPQNNALLEADSLVLQRAGKLLNQPLNFELKKNERMVIQGENGSGKSTLIKAMLGQNEL
CCCCCCCEEHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCCCCCHHHHHHHHHCCCCE
IAEGNLKIRENLRISYLPQDFDQLQGTLEQFAAEKEVEVQDLLAMLRKLGFERTMFDYRI
EECCCCEEECCCEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHH
EQMSMGQKRKVALARSLCEEANLYIWDEPLNYLDVITREQIQNLVLKFKPTLLVVEHDRE
HHHHCCCHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCHH
FVQKIATQTVNLKK
HHHHHHHHCCCCCC
>Mature Secondary Structure 
GIIQLKNVSFSYDNQIKPVFDQVALEIDASWKLGLVGRNGRGKTTLMKILQNQVEYEGK
CEEEEECCCCCCCCCCHHHHHHHHEEECCCEEEEEEECCCCCHHHHHHHHHHHHCCCCC
VETNLKFNYFPAKITEPQDSVRMILMKITGRDYSDFWEVERELDQIGLAEEILEQTYASL
EECCEEEEEECCCCCCCHHHHHEEEHEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHC
SPGQQTKALLAAMFADQNSFQLIDEPTNHLDAAGRDLLAKYLKQKQGYIVVSHDRYFLNQ
CCCHHHHHHHHHHHCCCCCCEECCCCCHHHHHCCHHHHHHHHHCCCCEEEEECCHHHHHH
VIDHVISIDRAQISSFKGNYETWAAERANADEREISLNATMKKDIKKLEQATRQKQEWSR
HHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHH
ATERKKAGAPDKGFVGHKAAKVMSKALNIRDRAEKKLTDKKQLLKNIEIQDELQLNYQPY
HHHHHHCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCC
LGPQNNALLEADSLVLQRAGKLLNQPLNFELKKNERMVIQGENGSGKSTLIKAMLGQNEL
CCCCCCCEEHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCCCCCHHHHHHHHHCCCCE
IAEGNLKIRENLRISYLPQDFDQLQGTLEQFAAEKEVEVQDLLAMLRKLGFERTMFDYRI
EECCCCEEECCCEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHH
EQMSMGQKRKVALARSLCEEANLYIWDEPLNYLDVITREQIQNLVLKFKPTLLVVEHDRE
HHHHCCCHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCHH
FVQKIATQTVNLKK
HHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]