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The map label for this gene is efp

Identifier: 116332640

GI number: 116332640

Start: 252485

End: 253051

Strand: Reverse

Name: efp

Synonym: LBJ_4220

Alternate gene names: 116332640

Gene position: 253051-252485 (Counterclockwise)

Preceding gene: 116332646

Following gene: 116332639

Centisome position: 84.42

GC content: 41.62

Gene sequence:

>567_bases
ATGACTCTTGGTATCACAGAAGTAAAAAAAGGTATGGTTCTCAAAGTAGAAGGGGATCTTTACTCGGTCGTTAAAACCGA
ATTCGTAAACCCGGGTAAAGGTTCGGCTTTTATCAGAACGAAGCTAAAGAATCTTACCAAAAACAGTTCGATTGAGCGTA
CTTTCAAAGCGGCGGAAAAATTGGAGAGTGTCGAATTAGAAAAACGAAATATGACCATCTGCTACACCGAAGGGAACGAT
ATCATCTTTATGGACTCCAACGATTTTGAACAAATGCCGGTGTCTAAAGAATATGTGGAAGATATTCTTCCTTTTTTAAA
AGAGGAAACTCCGATGGAAGTTACTTTCTACGAAGGAAAACCGATCGGAGTGATTCCTCCGAACTTTTCCATTCTTGAAG
TGACGTACGCCGAAGAAGGTCTTAAAGGAGACACGTCCGGTACGGCTCAAAAAAGAGTCACCGTGGAAACCGGAGGAGAA
ATCAACGTTCCGATATTCGTAAAGCAGGGAGATGTAATTAAAATAGACCTGCGGGATCTCACTTACGTGGAAAGGGTGAG
TAGATAA

Upstream 100 bases:

>100_bases
AGAACGGCTCCCTACGGGTCGCCGTTCTGGGTGTCTTTTTCTTGACAGGGGGCCCGTTTCAAAAGAAATAGAAAGGGGCA
AATTATTCCTAGGACAATCC

Downstream 100 bases:

>100_bases
TACAAGCTGCGGAGATTTTTATGGCGACGATAGTACGACAAAAAGGTTTGGCACCGATCGAGGAAACGAGCGAAGTAAAA
TCCTTTCTTAAAGAAAGAGG

Product: translation elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MTLGITEVKKGMVLKVEGDLYSVVKTEFVNPGKGSAFIRTKLKNLTKNSSIERTFKAAEKLESVELEKRNMTICYTEGND
IIFMDSNDFEQMPVSKEYVEDILPFLKEETPMEVTFYEGKPIGVIPPNFSILEVTYAEEGLKGDTSGTAQKRVTVETGGE
INVPIFVKQGDVIKIDLRDLTYVERVSR

Sequences:

>Translated_188_residues
MTLGITEVKKGMVLKVEGDLYSVVKTEFVNPGKGSAFIRTKLKNLTKNSSIERTFKAAEKLESVELEKRNMTICYTEGND
IIFMDSNDFEQMPVSKEYVEDILPFLKEETPMEVTFYEGKPIGVIPPNFSILEVTYAEEGLKGDTSGTAQKRVTVETGGE
INVPIFVKQGDVIKIDLRDLTYVERVSR
>Mature_187_residues
TLGITEVKKGMVLKVEGDLYSVVKTEFVNPGKGSAFIRTKLKNLTKNSSIERTFKAAEKLESVELEKRNMTICYTEGNDI
IFMDSNDFEQMPVSKEYVEDILPFLKEETPMEVTFYEGKPIGVIPPNFSILEVTYAEEGLKGDTSGTAQKRVTVETGGEI
NVPIFVKQGDVIKIDLRDLTYVERVSR

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=180, Percent_Identity=39.4444444444444, Blast_Score=145, Evalue=1e-36,
Organism=Escherichia coli, GI87082061, Length=184, Percent_Identity=28.2608695652174, Blast_Score=83, Evalue=1e-17,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_LEPBJ (Q04NC1)

Other databases:

- EMBL:   CP000351
- RefSeq:   YP_802357.1
- ProteinModelPortal:   Q04NC1
- SMR:   Q04NC1
- STRING:   Q04NC1
- GeneID:   4412292
- GenomeReviews:   CP000351_GR
- KEGG:   lbj:LBJ_4220
- eggNOG:   COG0231
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- PhylomeDB:   Q04NC1
- ProtClustDB:   PRK00529
- BioCyc:   LBOR355277:LBJ_4220-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 21145; Mature: 21013

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLGITEVKKGMVLKVEGDLYSVVKTEFVNPGKGSAFIRTKLKNLTKNSSIERTFKAAEK
CCCCHHHHCCCEEEEECCCEEEEHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHH
LESVELEKRNMTICYTEGNDIIFMDSNDFEQMPVSKEYVEDILPFLKEETPMEVTFYEGK
HHHHEEECCCEEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCC
PIGVIPPNFSILEVTYAEEGLKGDTSGTAQKRVTVETGGEINVPIFVKQGDVIKIDLRDL
EEEEECCCCEEEEEEECCCCCCCCCCCCCEEEEEEECCCEEEEEEEEECCCEEEEEHHHH
TYVERVSR
HHHHHHCC
>Mature Secondary Structure 
TLGITEVKKGMVLKVEGDLYSVVKTEFVNPGKGSAFIRTKLKNLTKNSSIERTFKAAEK
CCCHHHHCCCEEEEECCCEEEEHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHH
LESVELEKRNMTICYTEGNDIIFMDSNDFEQMPVSKEYVEDILPFLKEETPMEVTFYEGK
HHHHEEECCCEEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCC
PIGVIPPNFSILEVTYAEEGLKGDTSGTAQKRVTVETGGEINVPIFVKQGDVIKIDLRDL
EEEEECCCCEEEEEEECCCCCCCCCCCCCEEEEEEECCCEEEEEEEEECCCEEEEEHHHH
TYVERVSR
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA