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The map label for this gene is cobU [H]

Identifier: 116332617

GI number: 116332617

Start: 219164

End: 219736

Strand: Direct

Name: cobU [H]

Synonym: LBJ_4190

Alternate gene names: 116332617

Gene position: 219164-219736 (Clockwise)

Preceding gene: 116332616

Following gene: 116332618

Centisome position: 73.11

GC content: 39.44

Gene sequence:

>573_bases
ATGGCCGACATAACTTTGATTACCGGAGGTTGTAGAAGCGGCAAAAGCGGATTGGCGCTTAAGTTAGCAAACGAAATCCA
GGGGAAAAAATACTTTGTCGCGACCTGTCCCGCTTTTGACGAGGAGACCAATCAAAGAATCCTAAAACACAAAAAAGAAA
GGGAATTTCTTCCATGGGAAACTATAGAAGAAGAATTCAATCTTTCGAATGTATTCAAACCAGGACGTTTGTCAGAATCT
TCCATAGTCGTAATCGATTGCCTCAGCCTCTGGATTAACAATCTTTTGTATCAGGCGAACAAAAAAAATTCCGAAATCGA
CGAAACCACAATTAAAAAGAATTGTATGGAACTCATTCACAGTATTCAAAATTCCGAAGCAAGACATGTGATATGCGTAA
GCAATGAAGTAGGACTTGGGCTCGTCCCAGAAAATAAAATAGGAAGGATCTATAGAGATCTCCTGGGAATATGTAACCAA
TCAATAGCACATAACGCCAATTTCGTATACTTCATGGTAAGCGGCATTCCGCTTAAGATAAAAGAAAACAAAGGGAGCCC
GAAAATAGTATGA

Upstream 100 bases:

>100_bases
AATTCATTTCGGAAATTGGAAAAGAAAAAATTTTTATGGAAATGAAACAAGCTCTTCCCATAAGTCTGATCGATCAATGT
ATTATTCAAAAGGAATATAA

Downstream 100 bases:

>100_bases
ATCGATCGGGGCATGGAGGGAATCTTATCGAACTCGCGCAAAAAGCAAGATGTAAACCAAATGAAATCTTGGATTTTTCC
GTCAACGTCAATCCCCTCGG

Product: bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 190; Mature: 189

Protein sequence:

>190_residues
MADITLITGGCRSGKSGLALKLANEIQGKKYFVATCPAFDEETNQRILKHKKEREFLPWETIEEEFNLSNVFKPGRLSES
SIVVIDCLSLWINNLLYQANKKNSEIDETTIKKNCMELIHSIQNSEARHVICVSNEVGLGLVPENKIGRIYRDLLGICNQ
SIAHNANFVYFMVSGIPLKIKENKGSPKIV

Sequences:

>Translated_190_residues
MADITLITGGCRSGKSGLALKLANEIQGKKYFVATCPAFDEETNQRILKHKKEREFLPWETIEEEFNLSNVFKPGRLSES
SIVVIDCLSLWINNLLYQANKKNSEIDETTIKKNCMELIHSIQNSEARHVICVSNEVGLGLVPENKIGRIYRDLLGICNQ
SIAHNANFVYFMVSGIPLKIKENKGSPKIV
>Mature_189_residues
ADITLITGGCRSGKSGLALKLANEIQGKKYFVATCPAFDEETNQRILKHKKEREFLPWETIEEEFNLSNVFKPGRLSESS
IVVIDCLSLWINNLLYQANKKNSEIDETTIKKNCMELIHSIQNSEARHVICVSNEVGLGLVPENKIGRIYRDLLGICNQS
IAHNANFVYFMVSGIPLKIKENKGSPKIV

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=184, Percent_Identity=35.3260869565217, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 21368; Mature: 21237

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADITLITGGCRSGKSGLALKLANEIQGKKYFVATCPAFDEETNQRILKHKKEREFLPWE
CCCEEEEECCCCCCCCCEEEEEHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCHH
TIEEEFNLSNVFKPGRLSESSIVVIDCLSLWINNLLYQANKKNSEIDETTIKKNCMELIH
HHHHHCCHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
SIQNSEARHVICVSNEVGLGLVPENKIGRIYRDLLGICNQSIAHNANFVYFMVSGIPLKI
HHCCCCCCEEEEECCCCCEEECCCHHHHHHHHHHHHHHCHHHHCCCCEEEEEECCEEEEE
KENKGSPKIV
ECCCCCCCCC
>Mature Secondary Structure 
ADITLITGGCRSGKSGLALKLANEIQGKKYFVATCPAFDEETNQRILKHKKEREFLPWE
CCEEEEECCCCCCCCCEEEEEHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCHH
TIEEEFNLSNVFKPGRLSESSIVVIDCLSLWINNLLYQANKKNSEIDETTIKKNCMELIH
HHHHHCCHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
SIQNSEARHVICVSNEVGLGLVPENKIGRIYRDLLGICNQSIAHNANFVYFMVSGIPLKI
HHCCCCCCEEEEECCCCCEEECCCHHHHHHHHHHHHHHCHHHHCCCCEEEEEECCEEEEE
KENKGSPKIV
ECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1655696 [H]