| Definition | Leptospira borgpetersenii serovar Hardjo-bovis JB197 chromosome 2, complete sequence. |
|---|---|
| Accession | NC_008511 |
| Length | 299,762 |
Click here to switch to the map view.
The map label for this gene is cobQ [H]
Identifier: 116332618
GI number: 116332618
Start: 219733
End: 222330
Strand: Direct
Name: cobQ [H]
Synonym: LBJ_4191
Alternate gene names: 116332618
Gene position: 219733-222330 (Clockwise)
Preceding gene: 116332617
Following gene: 116332619
Centisome position: 73.3
GC content: 39.34
Gene sequence:
>2598_bases ATGAATCGATCGGGGCATGGAGGGAATCTTATCGAACTCGCGCAAAAAGCAAGATGTAAACCAAATGAAATCTTGGATTT TTCCGTCAACGTCAATCCCCTCGGGTTCCCTGAATGGTTAAGACCTTTCATTAATTCTAAAATCAGCGATCTTGTCTCTT ATCCGGATCCAAATTATACATCTTTAAAAGAAACAATACATTCAAAATATAAAATACCGAAAGAGCAAATCGTTCTTGGA AACGGCGCGTCCGAACTCATTCTTCAAATCCCTTTTGTGGCCAACACAGATTACGCTTTGATCGCAACCCCTTGTTATAG CGGATATAAAGAAGGAGTTTCGTTGAAAGACATTCCTTGTACGGAGATAGTTCTCAAAGAGAAAAATTTCTTTCGTTTAG ACTTTGATGAAGTTCGAGACATCTTAAAATCAAAATCAGATCAAAAAGCGTTAGTTTTTCTAGGACATCCGAACAATCCA ACAGGTATTACTCTCAATAGAAACGAAACTCTAAAACTCGTTTCCGAGTTTCCGAGTTATACTTTTGTCATCGATGAGTC CTTCATCGATCTTTGTCCGAAAGGAACTTCTTTTCTCAATGACAGAACCAATAATATGATTCTAATTCGATCCATGACTA AAGTTCTTGCAATTCCCGGCCTGAGAATCGGAGTTTGTTTTGCCTCTCCTCAAATTTGTTCTTCACTTTCGAAAAGACTC CCGACTTGGAACGTAAACACGCTCGCCGCCTCGGTTTACGAAAAGGCAATTGCAGAAGATGAATACACAGAAAAATCAAA ACAAAAAGTTCTAAGCTGGAAGGAAAAGTTAGAATTCGATCTTTCTAATTTAGAGTTTCTTCATATATTTCCAAGCGATA CGAATTTTATTCTTATTAAAATATTAAAAGATCGAAGTGCGACAGAATTGACACAAGAACTACTCCAAAAATATAGGATC GCGGTTCGAGACTGCGGAAACTTTTCCGGGTTATCCGAAAATTTCATTCGAATTGCAGTGCGCACTCCGGAAGAAAATGA AAAAATTATAAACGCGTTTTTTGATATATTTTACAGCACAAATAAGATCCATAAAATTCCGAAAAAAACAACACCTGCAA TTATGTTGCAAGGAACCGCGTCCAATGTGGGCAAAAGCATTTTAACCGCCGCGCTCTGTCGTATTTTAGCGCAAGAAGGA GTGAAAGTAGCACCTTTCAAATCGCAGAATATGGCTCTCAATTCGTTTGTCACTTCGAACGGAAGAGAAATTGGACGAGC ACAAGCGTTACAAGCACAGGCCGCAAAAATCCCCCCCGATATAAGGATGAATCCGATCCTCCTCAAACCTTCAAGTGAAA AGGACTCACAAGTAATCGTTAACGGAATACCCGTAGGTGCAATGAGTTTCAAAGATTACACTGAATACAAATCGATCGCG TTCGAAGAAGTGAAAAAATCCTATGATTCTCTTTCATCCGAATATAATGTAATTATAATAGAGGGAGCTGGAAGTGCGTC CGAAGTGAATTTAAAAAAGAACGATTTAGTCAATATGAGAATGGCTGAATATGCGAAAGCGAAAGTGCTACTTGTTGGTA ATATCGATCACGGAGGAATCTTCGGTTCGATTTTAGGGACGATGGAAACTCTTGTGGAATGGGAAAGAAAACTCGTTTTT GGTTTTATTATCAATCGTTTTCGAGGAGCAAAGGAATTCCTAAAAACTGGCACAGAATATATCGAAGAATACACTGGTAA ACCAGTTCTTGGAATCGTTTCACATCTTCAGAATCTGGGTTTACCAGAAGAGGATTCCCTTGAATTCAAATCAGGAGCGT TAGATGATACGTCTAAATCGGAAGGAATAATAGATATTGCTTTGATCGATATTCCGAGAATTTCCAATCATACGGACATC GATGCGCTCAAATCCGAACCCGACGTTCGAGTGAGAATTGTGCGGACTTGCAAAGATTTGGGAGAACCGGACATTGTAAT TCTTCCCGGAAGCAAAAATGTAATTACCGACTTGGATCATTTACGCGACGTCGGATTAGCAGATCGAATTATCACACTCG CGCAAAACCAAAAAACCGACATAGTAGGGATTTGTGGCGGCTATCAAATGCTTGGAAGAAATATTTTCGACCCCTATAAA ATCGAAACCGATCGAAAAAGCGCAAAAGGACTTTCACTTTTACAAATTGAAAGTACATTAGAAAAAGACAAATCCCTCAA ACAAACAATCGCCACCCATATTCCGACCGGATGCGAAATCGAAGGATACGAGATTCATCACGGGAAAACGACTTCCACTG GAGAAAACACACGAGTAATCTTTTTAAGCGGAAAAACCGAAGAGTTGGGACATAGCGATCTAACGGGAAGAATTTGGGGA ACATACATCCACGGGGTTTTTGACAAGGACGAATTTCGCAGGAAATATCTGGATCAAATCCGAATCCGAAAGGGGAAACC ACCTTTGATCAATATCCAATTTTCTTATGATTTGGAAAAATCTTTGAATAGACTTGCCGAACACGTTAGACTCTCTTTAA ATATGGATTTAATCTATCAAACGTTAGGGCTCGGCTAA
Upstream 100 bases:
>100_bases TATGTAACCAATCAATAGCACATAACGCCAATTTCGTATACTTCATGGTAAGCGGCATTCCGCTTAAGATAAAAGAAAAC AAAGGGAGCCCGAAAATAGT
Downstream 100 bases:
>100_bases AATGCCTTGGATCATAACCTTGTCTATTGTCCTCGATTTGATATTCGGAGATCCGAGAAATACACCTCACCCAGTACGAG TAATCGGAAAATTTGCAAGG
Product: bifunctional cobyric acid synthase/cobyric acid decarboxylase and cobyric acid synthase/cobyric acidaminotransferase
Products: NA
Alternate protein names: Putative threonine-phosphate decarboxylase; L-threonine-O-3-phosphate decarboxylase; Cobyric acid synthase [H]
Number of amino acids: Translated: 865; Mature: 865
Protein sequence:
>865_residues MNRSGHGGNLIELAQKARCKPNEILDFSVNVNPLGFPEWLRPFINSKISDLVSYPDPNYTSLKETIHSKYKIPKEQIVLG NGASELILQIPFVANTDYALIATPCYSGYKEGVSLKDIPCTEIVLKEKNFFRLDFDEVRDILKSKSDQKALVFLGHPNNP TGITLNRNETLKLVSEFPSYTFVIDESFIDLCPKGTSFLNDRTNNMILIRSMTKVLAIPGLRIGVCFASPQICSSLSKRL PTWNVNTLAASVYEKAIAEDEYTEKSKQKVLSWKEKLEFDLSNLEFLHIFPSDTNFILIKILKDRSATELTQELLQKYRI AVRDCGNFSGLSENFIRIAVRTPEENEKIINAFFDIFYSTNKIHKIPKKTTPAIMLQGTASNVGKSILTAALCRILAQEG VKVAPFKSQNMALNSFVTSNGREIGRAQALQAQAAKIPPDIRMNPILLKPSSEKDSQVIVNGIPVGAMSFKDYTEYKSIA FEEVKKSYDSLSSEYNVIIIEGAGSASEVNLKKNDLVNMRMAEYAKAKVLLVGNIDHGGIFGSILGTMETLVEWERKLVF GFIINRFRGAKEFLKTGTEYIEEYTGKPVLGIVSHLQNLGLPEEDSLEFKSGALDDTSKSEGIIDIALIDIPRISNHTDI DALKSEPDVRVRIVRTCKDLGEPDIVILPGSKNVITDLDHLRDVGLADRIITLAQNQKTDIVGICGGYQMLGRNIFDPYK IETDRKSAKGLSLLQIESTLEKDKSLKQTIATHIPTGCEIEGYEIHHGKTTSTGENTRVIFLSGKTEELGHSDLTGRIWG TYIHGVFDKDEFRRKYLDQIRIRKGKPPLINIQFSYDLEKSLNRLAEHVRLSLNMDLIYQTLGLG
Sequences:
>Translated_865_residues MNRSGHGGNLIELAQKARCKPNEILDFSVNVNPLGFPEWLRPFINSKISDLVSYPDPNYTSLKETIHSKYKIPKEQIVLG NGASELILQIPFVANTDYALIATPCYSGYKEGVSLKDIPCTEIVLKEKNFFRLDFDEVRDILKSKSDQKALVFLGHPNNP TGITLNRNETLKLVSEFPSYTFVIDESFIDLCPKGTSFLNDRTNNMILIRSMTKVLAIPGLRIGVCFASPQICSSLSKRL PTWNVNTLAASVYEKAIAEDEYTEKSKQKVLSWKEKLEFDLSNLEFLHIFPSDTNFILIKILKDRSATELTQELLQKYRI AVRDCGNFSGLSENFIRIAVRTPEENEKIINAFFDIFYSTNKIHKIPKKTTPAIMLQGTASNVGKSILTAALCRILAQEG VKVAPFKSQNMALNSFVTSNGREIGRAQALQAQAAKIPPDIRMNPILLKPSSEKDSQVIVNGIPVGAMSFKDYTEYKSIA FEEVKKSYDSLSSEYNVIIIEGAGSASEVNLKKNDLVNMRMAEYAKAKVLLVGNIDHGGIFGSILGTMETLVEWERKLVF GFIINRFRGAKEFLKTGTEYIEEYTGKPVLGIVSHLQNLGLPEEDSLEFKSGALDDTSKSEGIIDIALIDIPRISNHTDI DALKSEPDVRVRIVRTCKDLGEPDIVILPGSKNVITDLDHLRDVGLADRIITLAQNQKTDIVGICGGYQMLGRNIFDPYK IETDRKSAKGLSLLQIESTLEKDKSLKQTIATHIPTGCEIEGYEIHHGKTTSTGENTRVIFLSGKTEELGHSDLTGRIWG TYIHGVFDKDEFRRKYLDQIRIRKGKPPLINIQFSYDLEKSLNRLAEHVRLSLNMDLIYQTLGLG >Mature_865_residues MNRSGHGGNLIELAQKARCKPNEILDFSVNVNPLGFPEWLRPFINSKISDLVSYPDPNYTSLKETIHSKYKIPKEQIVLG NGASELILQIPFVANTDYALIATPCYSGYKEGVSLKDIPCTEIVLKEKNFFRLDFDEVRDILKSKSDQKALVFLGHPNNP TGITLNRNETLKLVSEFPSYTFVIDESFIDLCPKGTSFLNDRTNNMILIRSMTKVLAIPGLRIGVCFASPQICSSLSKRL PTWNVNTLAASVYEKAIAEDEYTEKSKQKVLSWKEKLEFDLSNLEFLHIFPSDTNFILIKILKDRSATELTQELLQKYRI AVRDCGNFSGLSENFIRIAVRTPEENEKIINAFFDIFYSTNKIHKIPKKTTPAIMLQGTASNVGKSILTAALCRILAQEG VKVAPFKSQNMALNSFVTSNGREIGRAQALQAQAAKIPPDIRMNPILLKPSSEKDSQVIVNGIPVGAMSFKDYTEYKSIA FEEVKKSYDSLSSEYNVIIIEGAGSASEVNLKKNDLVNMRMAEYAKAKVLLVGNIDHGGIFGSILGTMETLVEWERKLVF GFIINRFRGAKEFLKTGTEYIEEYTGKPVLGIVSHLQNLGLPEEDSLEFKSGALDDTSKSEGIIDIALIDIPRISNHTDI DALKSEPDVRVRIVRTCKDLGEPDIVILPGSKNVITDLDHLRDVGLADRIITLAQNQKTDIVGICGGYQMLGRNIFDPYK IETDRKSAKGLSLLQIESTLEKDKSLKQTIATHIPTGCEIEGYEIHHGKTTSTGENTRVIFLSGKTEELGHSDLTGRIWG TYIHGVFDKDEFRRKYLDQIRIRKGKPPLINIQFSYDLEKSLNRLAEHVRLSLNMDLIYQTLGLG
Specific function: Catalyzes two activities which are involved in the adenosylcobalamin biosynthesis:decarboxylates L-threonine-O-3- phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cob
COG id: COG1492
COG function: function code H; Cobyric acid synthase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 GATase cobBQ-type domain [H]
Homologues:
Organism=Escherichia coli, GI1788332, Length=317, Percent_Identity=24.2902208201893, Blast_Score=82, Evalue=1e-16, Organism=Saccharomyces cerevisiae, GI6322075, Length=335, Percent_Identity=25.9701492537313, Blast_Score=106, Evalue=2e-23,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004839 - InterPro: IPR002586 - InterPro: IPR017929 - InterPro: IPR004459 - InterPro: IPR011698 - InterPro: IPR004838 - InterPro: IPR015424 - InterPro: IPR015421 - InterPro: IPR015422 [H]
Pfam domain/function: PF00155 Aminotran_1_2; PF01656 CbiA; PF07685 GATase_3 [H]
EC number: =4.1.1.81 [H]
Molecular weight: Translated: 96811; Mature: 96811
Theoretical pI: Translated: 7.36; Mature: 7.36
Prosite motif: PS00105 AA_TRANSFER_CLASS_1
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.3 %Cys (Translated Protein) 1.4 %Met (Translated Protein) 2.7 %Cys+Met (Translated Protein) 1.3 %Cys (Mature Protein) 1.4 %Met (Mature Protein) 2.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNRSGHGGNLIELAQKARCKPNEILDFSVNVNPLGFPEWLRPFINSKISDLVSYPDPNYT CCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHCHHHHHHHCCCCCCHH SLKETIHSKYKIPKEQIVLGNGASELILQIPFVANTDYALIATPCYSGYKEGVSLKDIPC HHHHHHHHHHCCCHHHEEECCCCCEEEEEECEECCCCEEEEECCCHHHHHCCCCCCCCCC TEIVLKEKNFFRLDFDEVRDILKSKSDQKALVFLGHPNNPTGITLNRNETLKLVSEFPSY HHEEEECCCEEEECHHHHHHHHHCCCCCCEEEEEECCCCCCCEEECCCCHHHHHHHCCCE TFVIDESFIDLCPKGTSFLNDRTNNMILIRSMTKVLAIPGLRIGVCFASPQICSSLSKRL EEEEECHHHHHCCCCCHHHCCCCCCEEEEEEHHHHHHCCCCEEEEEECCHHHHHHHHHHC PTWNVNTLAASVYEKAIAEDEYTEKSKQKVLSWKEKLEFDLSNLEFLHIFPSDTNFILIK CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEE ILKDRSATELTQELLQKYRIAVRDCGNFSGLSENFIRIAVRTPEENEKIINAFFDIFYST EECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCC NKIHKIPKKTTPAIMLQGTASNVGKSILTAALCRILAQEGVKVAPFKSQNMALNSFVTSN CHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEHHHHHCC GREIGRAQALQAQAAKIPPDIRMNPILLKPSSEKDSQVIVNGIPVGAMSFKDYTEYKSIA CHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCEEEEECCCCCCCCCHHHHHHHHHH FEEVKKSYDSLSSEYNVIIIEGAGSASEVNLKKNDLVNMRMAEYAKAKVLLVGNIDHGGI HHHHHHHHHHHCCCCCEEEEECCCCCCEECCCCCCCHHHHHHHHCCEEEEEEECCCCCCH FGSILGTMETLVEWERKLVFGFIINRFRGAKEFLKTGTEYIEEYTGKPVLGIVSHLQNLG HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC LPEEDSLEFKSGALDDTSKSEGIIDIALIDIPRISNHTDIDALKSEPDVRVRIVRTCKDL CCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHCCCCCCEEHHHHHHHHC GEPDIVILPGSKNVITDLDHLRDVGLADRIITLAQNQKTDIVGICGGYQMLGRNIFDPYK CCCCEEEECCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEECCCHHHHCCCCCCCCE IETDRKSAKGLSLLQIESTLEKDKSLKQTIATHIPTGCEIEGYEIHHGKTTSTGENTRVI ECCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCEECCEEEECCCCCCCCCCEEEE FLSGKTEELGHSDLTGRIWGTYIHGVFDKDEFRRKYLDQIRIRKGKPPLINIQFSYDLEK EEECCCHHCCCCCCCCCEEHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHH SLNRLAEHVRLSLNMDLIYQTLGLG HHHHHHHHHEEECCHHHHHHHHCCC >Mature Secondary Structure MNRSGHGGNLIELAQKARCKPNEILDFSVNVNPLGFPEWLRPFINSKISDLVSYPDPNYT CCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHCHHHHHHHCCCCCCHH SLKETIHSKYKIPKEQIVLGNGASELILQIPFVANTDYALIATPCYSGYKEGVSLKDIPC HHHHHHHHHHCCCHHHEEECCCCCEEEEEECEECCCCEEEEECCCHHHHHCCCCCCCCCC TEIVLKEKNFFRLDFDEVRDILKSKSDQKALVFLGHPNNPTGITLNRNETLKLVSEFPSY HHEEEECCCEEEECHHHHHHHHHCCCCCCEEEEEECCCCCCCEEECCCCHHHHHHHCCCE TFVIDESFIDLCPKGTSFLNDRTNNMILIRSMTKVLAIPGLRIGVCFASPQICSSLSKRL EEEEECHHHHHCCCCCHHHCCCCCCEEEEEEHHHHHHCCCCEEEEEECCHHHHHHHHHHC PTWNVNTLAASVYEKAIAEDEYTEKSKQKVLSWKEKLEFDLSNLEFLHIFPSDTNFILIK CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEE ILKDRSATELTQELLQKYRIAVRDCGNFSGLSENFIRIAVRTPEENEKIINAFFDIFYST EECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCC NKIHKIPKKTTPAIMLQGTASNVGKSILTAALCRILAQEGVKVAPFKSQNMALNSFVTSN CHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEHHHHHCC GREIGRAQALQAQAAKIPPDIRMNPILLKPSSEKDSQVIVNGIPVGAMSFKDYTEYKSIA CHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCEEEEECCCCCCCCCHHHHHHHHHH FEEVKKSYDSLSSEYNVIIIEGAGSASEVNLKKNDLVNMRMAEYAKAKVLLVGNIDHGGI HHHHHHHHHHHCCCCCEEEEECCCCCCEECCCCCCCHHHHHHHHCCEEEEEEECCCCCCH FGSILGTMETLVEWERKLVFGFIINRFRGAKEFLKTGTEYIEEYTGKPVLGIVSHLQNLG HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC LPEEDSLEFKSGALDDTSKSEGIIDIALIDIPRISNHTDIDALKSEPDVRVRIVRTCKDL CCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHCCCCCCEEHHHHHHHHC GEPDIVILPGSKNVITDLDHLRDVGLADRIITLAQNQKTDIVGICGGYQMLGRNIFDPYK CCCCEEEECCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEECCCHHHHCCCCCCCCE IETDRKSAKGLSLLQIESTLEKDKSLKQTIATHIPTGCEIEGYEIHHGKTTSTGENTRVI ECCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCEECCEEEECCCCCCCCCCEEEE FLSGKTEELGHSDLTGRIWGTYIHGVFDKDEFRRKYLDQIRIRKGKPPLINIQFSYDLEK EEECCCHHCCCCCCCCCEEHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHH SLNRLAEHVRLSLNMDLIYQTLGLG HHHHHHHHHEEECCHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 12712204 [H]