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The map label for this gene is murB [H]

Identifier: 116329251

GI number: 116329251

Start: 3188359

End: 3189315

Strand: Direct

Name: murB [H]

Synonym: LBL_2690

Alternate gene names: 116329251

Gene position: 3188359-3189315 (Clockwise)

Preceding gene: 116329249

Following gene: 116329257

Centisome position: 88.21

GC content: 38.45

Gene sequence:

>957_bases
ATGTCTCTTACTCTTTCCGAACTTCAGATCCGAACTCTGAAACAAACCTTAGAATCTTCTAAAATACCTTTTAAATCGGA
AGTACGCCTAGACATTCTATCTTCATTTAAAATCGGCGGAATTTGTCCGGTGGTTGTCGAACCTGAAAATTCAAACCAGG
TTTTGGAAACGCTTTTTATTTTTTACAAATCAGAAATACCTTGGAAAATTCTTGGAGGAGGTTCGAATCTTTTAATTTCG
GATCATCCGGACAACTTCGTCACTTTGCGTTTGTCCGGCAAATTTAAAGAATTTGAATATTTAGAAGGAGGAAAATTCCG
AATCGGATCGGCGACTAATACCACGCCGACATTTCGACAAATTTCACAATTAGGTTATACGGGAGCCGAGTTTTTAAGTA
CAATCCCGGGATGGACAGGTGGAGCGGTGATTCAGAATGCGGGTTGTTATGGAGGAGAACTTTTTGATTTGATTCAAACC
GTTGAATTTTTGAGAAACAACGAAATATTTGTTCGCAGTCCCTCCGAAATCAAACATGGTTACCGATTTACTGAATTTTT
AAACGAAAAGGATTCTATCATCTTAGGAATTGAAATTCTTCTCAAAGAAGGAAATTTAGAAGAAATTCAAACGTCGTTAA
AAGATAAAAGAGATAGAAGAAATTCTTCTCAACCTGAAAATAAAAAGAGTGCCGGTTCTGTTTTTAAAAATCCCAAAATT
TTTCTGGAGAATGGGAAGGAAATCAAAGCTTGGGAATTGATCGATCAAGCCGGTTTGAGGGGACAGATAAAAGGTGGGGC
TCAGATTTCTCCCGAACACTGTAATTTCATCGTAAATGTAGGAGCTGCGACCGCTGCAGATGTGAACTATCTGGTCGAAC
TCATTTTAGATAAGGTCTTTCAGACTACCGGAATTCGTCTAAATCGAGAGATCGAATACTTCGGCGATATACCGTGA

Upstream 100 bases:

>100_bases
ACATAAATTACCTCTTTTCTACAAGATCGAACCGATTTCGAATTTTCCTTGAGTTCTTTTTCTTGTGGTAGATAATCGAG
GAACGTCGTTTAGTGTTCCT

Downstream 100 bases:

>100_bases
TGTTGCCTTTCGAAGCCACGCTCTTAAAGTTGTTATTAACGTGAATTCGGCATAAAAAGAAATTTTTTCCCAAAGTAGAA
GTTCCCAAATTGTATTTGCA

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MSLTLSELQIRTLKQTLESSKIPFKSEVRLDILSSFKIGGICPVVVEPENSNQVLETLFIFYKSEIPWKILGGGSNLLIS
DHPDNFVTLRLSGKFKEFEYLEGGKFRIGSATNTTPTFRQISQLGYTGAEFLSTIPGWTGGAVIQNAGCYGGELFDLIQT
VEFLRNNEIFVRSPSEIKHGYRFTEFLNEKDSIILGIEILLKEGNLEEIQTSLKDKRDRRNSSQPENKKSAGSVFKNPKI
FLENGKEIKAWELIDQAGLRGQIKGGAQISPEHCNFIVNVGAATAADVNYLVELILDKVFQTTGIRLNREIEYFGDIP

Sequences:

>Translated_318_residues
MSLTLSELQIRTLKQTLESSKIPFKSEVRLDILSSFKIGGICPVVVEPENSNQVLETLFIFYKSEIPWKILGGGSNLLIS
DHPDNFVTLRLSGKFKEFEYLEGGKFRIGSATNTTPTFRQISQLGYTGAEFLSTIPGWTGGAVIQNAGCYGGELFDLIQT
VEFLRNNEIFVRSPSEIKHGYRFTEFLNEKDSIILGIEILLKEGNLEEIQTSLKDKRDRRNSSQPENKKSAGSVFKNPKI
FLENGKEIKAWELIDQAGLRGQIKGGAQISPEHCNFIVNVGAATAADVNYLVELILDKVFQTTGIRLNREIEYFGDIP
>Mature_317_residues
SLTLSELQIRTLKQTLESSKIPFKSEVRLDILSSFKIGGICPVVVEPENSNQVLETLFIFYKSEIPWKILGGGSNLLISD
HPDNFVTLRLSGKFKEFEYLEGGKFRIGSATNTTPTFRQISQLGYTGAEFLSTIPGWTGGAVIQNAGCYGGELFDLIQTV
EFLRNNEIFVRSPSEIKHGYRFTEFLNEKDSIILGIEILLKEGNLEEIQTSLKDKRDRRNSSQPENKKSAGSVFKNPKIF
LENGKEIKAWELIDQAGLRGQIKGGAQISPEHCNFIVNVGAATAADVNYLVELILDKVFQTTGIRLNREIEYFGDIP

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=328, Percent_Identity=24.390243902439, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 35563; Mature: 35432

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLTLSELQIRTLKQTLESSKIPFKSEVRLDILSSFKIGGICPVVVEPENSNQVLETLFI
CCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHH
FYKSEIPWKILGGGSNLLISDHPDNFVTLRLSGKFKEFEYLEGGKFRIGSATNTTPTFRQ
HHHCCCCEEEECCCCEEEEECCCCCEEEEEECCCCCCEEECCCCCEEECCCCCCCHHHHH
ISQLGYTGAEFLSTIPGWTGGAVIQNAGCYGGELFDLIQTVEFLRNNEIFVRSPSEIKHG
HHHCCCCHHHHHHHCCCCCCCHHEECCCCCCHHHHHHHHHHHHHHCCCEEEECCHHHHHC
YRFTEFLNEKDSIILGIEILLKEGNLEEIQTSLKDKRDRRNSSQPENKKSAGSVFKNPKI
HHHHHHHCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCHHHCHHHCCCEE
FLENGKEIKAWELIDQAGLRGQIKGGAQISPEHCNFIVNVGAATAADVNYLVELILDKVF
EEECCCEEHHHHHHHHCCCCEEECCCCEECHHHCCEEEECCCCHHHHHHHHHHHHHHHHH
QTTGIRLNREIEYFGDIP
HHCCCEEECEEEECCCCC
>Mature Secondary Structure 
SLTLSELQIRTLKQTLESSKIPFKSEVRLDILSSFKIGGICPVVVEPENSNQVLETLFI
CCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHH
FYKSEIPWKILGGGSNLLISDHPDNFVTLRLSGKFKEFEYLEGGKFRIGSATNTTPTFRQ
HHHCCCCEEEECCCCEEEEECCCCCEEEEEECCCCCCEEECCCCCEEECCCCCCCHHHHH
ISQLGYTGAEFLSTIPGWTGGAVIQNAGCYGGELFDLIQTVEFLRNNEIFVRSPSEIKHG
HHHCCCCHHHHHHHCCCCCCCHHEECCCCCCHHHHHHHHHHHHHHCCCEEEECCHHHHHC
YRFTEFLNEKDSIILGIEILLKEGNLEEIQTSLKDKRDRRNSSQPENKKSAGSVFKNPKI
HHHHHHHCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCHHHCHHHCCCEE
FLENGKEIKAWELIDQAGLRGQIKGGAQISPEHCNFIVNVGAATAADVNYLVELILDKVF
EEECCCEEHHHHHHHHCCCCEEECCCCEECHHHCCEEEECCCCHHHHHHHHHHHHHHHHH
QTTGIRLNREIEYFGDIP
HHCCCEEECEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA