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The map label for this gene is yrbE [H]

Identifier: 116329209

GI number: 116329209

Start: 3133437

End: 3134405

Strand: Reverse

Name: yrbE [H]

Synonym: LBL_2642

Alternate gene names: 116329209

Gene position: 3134405-3133437 (Counterclockwise)

Preceding gene: 116329210

Following gene: 116329208

Centisome position: 86.72

GC content: 40.56

Gene sequence:

>969_bases
ATGACAGAAAGAGTTAAACTCGGCGTGATCGGAGCCGGTCATATGGGGCAGTATCACGTAAATGTTGCCAAAACCCTTAA
CGACGCAACCCTGGTTGGAATTTATGACTCGGACTTAGAAAGAGCAAAACAAATTGCGGAAAAACACAAAACTTTGTCGT
TCTCTACGATCGACGATTTGATCTCAAAAACGGATGCGGTAGTTATCGCTGTTCCCACTTTTTTACATCACGAAATTGCA
AAGAAAGCTTTGCAAGCCAACAAACACGTATTAGTTGAAAAGCCGATTGCGGAAACTACCGAGCAGGCCAAAGAACTCGT
AAAAATTGCCGCAGACAAAAATTTAATTCTTCTTGTGGGTCATGTGGAGCGTTTCAACGGTGCAGTATTAGAATTAGGTA
AAATTGTAAAAGATCCCTTACTTATCGAGTCGAGAAGGCTTGCGCCTTTTAATCCGAGAATCAAAGACGTGGGCGTCGTT
CTCGATATGATGATTCACGATATTGATATCGTGTTAAATCTGGTCAATTCTCCCGTTAAAAAGCTTTCCGCTTCGGGGAC
AAAGGTATTGTCCGCTCACGAGGATGTCGCAAACGTCGTACTTGAATTTGAGAACGGATGTCTCGCAAGTATTACCGCGT
CCAGAACGACTCAAGCGAAAATTAGAACCTTGAATATCACTCAGAAAGACGTATATATTATGCTCGATTTTACGGATCAG
GAAATCGAACTGCATAGACAAGCTACTTCCGATATTCTTCTTTTATCCGAAGAGATTAAGTATCGGCAAGAATCGATTGT
GGAAAAGATTTTTGTTCATAAGGATAATCCGCTCAAACAAGAACAGGAACATTTTATCCGTTGTATCAGAAAAGAAACGG
ATCCGATTGTGAATAGAAATTCCGACGTTTCCACTTTGGAAATCACTTATCAAATTCTTTCTGAAATCCACGGAACTTCT
AAAAAGTAA

Upstream 100 bases:

>100_bases
AATTACCAAACCGTAAAATTTTTAGGACAAACCTTCGTAAAAAGTCGAGAAGACATTTTTCGAATAACACAACCTGATCG
CAAAACTAAAAGGAAATACA

Downstream 100 bases:

>100_bases
TCCGGTCTAAAACTGGTTAAAATATGGAAGAAACTTATAACGGAAAAATTCTAATCTCCAACTCTTCGATCGTTATGGAC
TATTTCAACCAAACGGTTAT

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MTERVKLGVIGAGHMGQYHVNVAKTLNDATLVGIYDSDLERAKQIAEKHKTLSFSTIDDLISKTDAVVIAVPTFLHHEIA
KKALQANKHVLVEKPIAETTEQAKELVKIAADKNLILLVGHVERFNGAVLELGKIVKDPLLIESRRLAPFNPRIKDVGVV
LDMMIHDIDIVLNLVNSPVKKLSASGTKVLSAHEDVANVVLEFENGCLASITASRTTQAKIRTLNITQKDVYIMLDFTDQ
EIELHRQATSDILLLSEEIKYRQESIVEKIFVHKDNPLKQEQEHFIRCIRKETDPIVNRNSDVSTLEITYQILSEIHGTS
KK

Sequences:

>Translated_322_residues
MTERVKLGVIGAGHMGQYHVNVAKTLNDATLVGIYDSDLERAKQIAEKHKTLSFSTIDDLISKTDAVVIAVPTFLHHEIA
KKALQANKHVLVEKPIAETTEQAKELVKIAADKNLILLVGHVERFNGAVLELGKIVKDPLLIESRRLAPFNPRIKDVGVV
LDMMIHDIDIVLNLVNSPVKKLSASGTKVLSAHEDVANVVLEFENGCLASITASRTTQAKIRTLNITQKDVYIMLDFTDQ
EIELHRQATSDILLLSEEIKYRQESIVEKIFVHKDNPLKQEQEHFIRCIRKETDPIVNRNSDVSTLEITYQILSEIHGTS
KK
>Mature_321_residues
TERVKLGVIGAGHMGQYHVNVAKTLNDATLVGIYDSDLERAKQIAEKHKTLSFSTIDDLISKTDAVVIAVPTFLHHEIAK
KALQANKHVLVEKPIAETTEQAKELVKIAADKNLILLVGHVERFNGAVLELGKIVKDPLLIESRRLAPFNPRIKDVGVVL
DMMIHDIDIVLNLVNSPVKKLSASGTKVLSAHEDVANVVLEFENGCLASITASRTTQAKIRTLNITQKDVYIMLDFTDQE
IELHRQATSDILLLSEEIKYRQESIVEKIFVHKDNPLKQEQEHFIRCIRKETDPIVNRNSDVSTLEITYQILSEIHGTSK
K

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI87082405, Length=279, Percent_Identity=23.6559139784946, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1787307, Length=308, Percent_Identity=25.6493506493506, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787574, Length=197, Percent_Identity=30.4568527918782, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87081947, Length=195, Percent_Identity=27.6923076923077, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789848, Length=140, Percent_Identity=32.1428571428571, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36057; Mature: 35926

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTERVKLGVIGAGHMGQYHVNVAKTLNDATLVGIYDSDLERAKQIAEKHKTLSFSTIDDL
CCCEEEEEEEECCCCCEEEEEHHHHCCCEEEEEEECHHHHHHHHHHHHHHCCCHHHHHHH
ISKTDAVVIAVPTFLHHEIAKKALQANKHVLVEKPIAETTEQAKELVKIAADKNLILLVG
HHCCCEEEEEECHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHCCCCEEEEEE
HVERFNGAVLELGKIVKDPLLIESRRLAPFNPRIKDVGVVLDMMIHDIDIVLNLVNSPVK
CHHHHCCHHHHHHHHHCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLSASGTKVLSAHEDVANVVLEFENGCLASITASRTTQAKIRTLNITQKDVYIMLDFTDQ
HHCCCCCEEHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEEEEECCCEEEEEECCCH
EIELHRQATSDILLLSEEIKYRQESIVEKIFVHKDNPLKQEQEHFIRCIRKETDPIVNRN
HHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCC
SDVSTLEITYQILSEIHGTSKK
CCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TERVKLGVIGAGHMGQYHVNVAKTLNDATLVGIYDSDLERAKQIAEKHKTLSFSTIDDL
CCEEEEEEEECCCCCEEEEEHHHHCCCEEEEEEECHHHHHHHHHHHHHHCCCHHHHHHH
ISKTDAVVIAVPTFLHHEIAKKALQANKHVLVEKPIAETTEQAKELVKIAADKNLILLVG
HHCCCEEEEEECHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHCCCCEEEEEE
HVERFNGAVLELGKIVKDPLLIESRRLAPFNPRIKDVGVVLDMMIHDIDIVLNLVNSPVK
CHHHHCCHHHHHHHHHCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLSASGTKVLSAHEDVANVVLEFENGCLASITASRTTQAKIRTLNITQKDVYIMLDFTDQ
HHCCCCCEEHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEEEEECCCEEEEEECCCH
EIELHRQATSDILLLSEEIKYRQESIVEKIFVHKDNPLKQEQEHFIRCIRKETDPIVNRN
HHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCC
SDVSTLEITYQILSEIHGTSKK
CCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9025289 [H]