| Definition | Leptospira borgpetersenii serovar Hardjo-bovis L550 chromosome 1, complete sequence. |
|---|---|
| Accession | NC_008508 |
| Length | 3,614,446 |
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The map label for this gene is slt [H]
Identifier: 116328934
GI number: 116328934
Start: 2752763
End: 2755015
Strand: Direct
Name: slt [H]
Synonym: LBL_2330
Alternate gene names: 116328934
Gene position: 2752763-2755015 (Clockwise)
Preceding gene: 116328926
Following gene: 116328935
Centisome position: 76.16
GC content: 43.05
Gene sequence:
>2253_bases ATGAAAAAATTCGCCCTAACCAGCCTACTCTTATTCATTTTCGGCAACCTTTACGCAAACGATGATCTCAAATATCTGAT CAAATCTTACAGTCTTCAAAAAATCCACCGCATTTTTCGGGAAAGGCACCCGGGTACGGAATCCGAGACCTACGCGTTAA TCCGATACCATGAAGAACATCCGAATGGAAGCCGGGATAAAAAATTCGCTTACCTGGTTTCTCTTCTTAAAGGAAAAATC GTGCTCTCGCCCGGAAGACAAGATCTTCTGGAGATTCTCCATTCCCCGCTACCCTCTACCTCTGCTATTACAAAACTGTC TCTCTGGAAACTCTACGAGGAAAGTGCGCACAGAAAAATTTTGGGAAGGGGAGAATTAATCGATCTTTTAAAAAAATTTC CCAGAGAAAACGATCCTTTAAGTCAAAACGCGATCTCGGAAATTTTCAGAATCTATTACGAAGCCGGAATGATCCAAGAA TGTTTGGAATTCGTCAAAAGTTTTTCCGACCGGGAAAAGTCGGAGATTTTTTCCCCGATGATCTTATACCGTTATGCGAA ATCTCTTTATAAATCCGGGGACACAGAAAAAGCCGAGGCCATCTTCTATTCGATTCTGGAAGATTCCTCCGTTTTTTCCT CCGTCAAAAAATTTATCCAAGTGGATCTTCAAATTTGGAAAGGAAACTCCTTTTATACTTCCTTAACTCCCGAACGGGCG GCCTTGTTTCTCCCGCATTTGGATTCTTCCGAAAGAAAGCATCTAATCTTATCGAAAGATCTTAAAAAAGTTTCCTTTTC CAAAGGAGAAGCGTTTCGTAACACCGCAAGAGCCCTCATAACCCTCGAACCGGAAGTTCTCCCCGACTTCTTTAAAAGAA ATGCGAATCTCGCAAAGTCCAATCCGTATTTTACGGCCGCAATATCGAGAGAACTCACAAACCGGAATCTTTCCGGTAAG GCTTTGAATTTATTAAACGACGTGAATCCTGAAAAAAACGAAGAGGTTCTTTACAGTTACGCAAGGGCTTATAAAAAACG GGGAAACAAGAATTTATATTTCAGAAATCTAATAGACTCTCTCGAAAAAAGCCCCACAAATTTAATCCGACAAGACGAAC TTATCGATCTTCTGACCGGAGGTCACAAACATTTTTTGGGAGATGCTTACTGGAAGGACGCCCTCCGTAAAATTCCGGAT CTTCCCGTCAAAGGAAGACTCGTATATTGGTATCTTCGTTTCTTAAAACAAAACGGAAGAACCGAAGAACTGAATTCCTG GCTTAAGTCCTATTACAGATATATCCCGGGCTCCTACTATACTCGCGTTATCAGAGAGGAATTCCAGGAGGAAATTTCCT CTTTTCCGCTTCCTTCCAATCCGACTTGGAACAAGGACAATCTCTTCGAGTATCTTTCTTTAACCGCGGGAATTCCGGAA CTTTCAGGAAAAATTCTGGGAAAGGATTTGGACTTTGCAACGCAAGCCGCGGCATTTCAATTGAACGTTAGGATCGACGA CGCTCATTCCACAATTCGAGGGAACCGTTATCTGCAATCGGCAAAGGAATACCTGGAAGTCGGAGAGATGGCTTACGCGC TTTCCTTAGTTCAAAGGTACAAAGTCCGACAAGGAATCGGAGAAAACGAAAAGGAAGAAATTCTCGCGGCTCTCGGAGAA CAAACCGGAACTCCTTACTTGACCGTCTTTTACACAAGATCTCTGATGAAAAAAGAAAAACTCAGCGACGATGTCATCCT TCTTCCATCCAAACTCGCCGCAAGAATTTACCCGAGACCACATAGAGGACTCGTAACTTCCGTTTCCCAAAACGTCGGAA TCGAAGAGGACATCGTCTATGCGATCATGCGTCAGGAATCTTTTTTCAAAGAGAATGCAACTTCGATTTCGAATGCGCGA GGGCTGATGCAGATTATGGGGCCGACAGGAAAAGAAATCGCTAAAAGAATGAATCTCGATTCCTATTCCCTGTTTGATCC GGAAGTTTCCATCGAAATGGGCGCGAGATTTTTACGCTATCTCGTCGCCTCCAACGGAAACAGTCTTCAATGGGCTTCGA TCGCTTATAACGGCGGGCCGGGAAATCTCCGTAAATGGAAACGAAACCATTACCGCGGAGACTTCAATCATTTCTTGGAA GAACTCCCGATCAAAGAACCGAGAGACTACTGTAGAATTGTCAGTTCGAACTATTACAATTATCAGAATTTACGGAAGTA TAAGAATCTTTGA
Upstream 100 bases:
>100_bases CCGGCCAGAGACGGTCCGTTTTTTCTTTTTCCAGGATTTGCATGGGAATTTCCTTTTTGCGATTGAATCCTTAGGCCGAA AAGGTAAGTAAAGAATACGA
Downstream 100 bases:
>100_bases AGAAATTATTTCATTTTGCTTGTATCAACACTTGATTCTTTTCTATTTCTTCTTGAATCCAGCGTAGACTCTTCTTTGAG AACAAAAACCACAGTTTTCA
Product: transglycosylase
Products: 1,6-Anhydrobond [C]
Alternate protein names: Exomuramidase; Peptidoglycan lytic exotransglycosylase; Slt70 [H]
Number of amino acids: Translated: 750; Mature: 750
Protein sequence:
>750_residues MKKFALTSLLLFIFGNLYANDDLKYLIKSYSLQKIHRIFRERHPGTESETYALIRYHEEHPNGSRDKKFAYLVSLLKGKI VLSPGRQDLLEILHSPLPSTSAITKLSLWKLYEESAHRKILGRGELIDLLKKFPRENDPLSQNAISEIFRIYYEAGMIQE CLEFVKSFSDREKSEIFSPMILYRYAKSLYKSGDTEKAEAIFYSILEDSSVFSSVKKFIQVDLQIWKGNSFYTSLTPERA ALFLPHLDSSERKHLILSKDLKKVSFSKGEAFRNTARALITLEPEVLPDFFKRNANLAKSNPYFTAAISRELTNRNLSGK ALNLLNDVNPEKNEEVLYSYARAYKKRGNKNLYFRNLIDSLEKSPTNLIRQDELIDLLTGGHKHFLGDAYWKDALRKIPD LPVKGRLVYWYLRFLKQNGRTEELNSWLKSYYRYIPGSYYTRVIREEFQEEISSFPLPSNPTWNKDNLFEYLSLTAGIPE LSGKILGKDLDFATQAAAFQLNVRIDDAHSTIRGNRYLQSAKEYLEVGEMAYALSLVQRYKVRQGIGENEKEEILAALGE QTGTPYLTVFYTRSLMKKEKLSDDVILLPSKLAARIYPRPHRGLVTSVSQNVGIEEDIVYAIMRQESFFKENATSISNAR GLMQIMGPTGKEIAKRMNLDSYSLFDPEVSIEMGARFLRYLVASNGNSLQWASIAYNGGPGNLRKWKRNHYRGDFNHFLE ELPIKEPRDYCRIVSSNYYNYQNLRKYKNL
Sequences:
>Translated_750_residues MKKFALTSLLLFIFGNLYANDDLKYLIKSYSLQKIHRIFRERHPGTESETYALIRYHEEHPNGSRDKKFAYLVSLLKGKI VLSPGRQDLLEILHSPLPSTSAITKLSLWKLYEESAHRKILGRGELIDLLKKFPRENDPLSQNAISEIFRIYYEAGMIQE CLEFVKSFSDREKSEIFSPMILYRYAKSLYKSGDTEKAEAIFYSILEDSSVFSSVKKFIQVDLQIWKGNSFYTSLTPERA ALFLPHLDSSERKHLILSKDLKKVSFSKGEAFRNTARALITLEPEVLPDFFKRNANLAKSNPYFTAAISRELTNRNLSGK ALNLLNDVNPEKNEEVLYSYARAYKKRGNKNLYFRNLIDSLEKSPTNLIRQDELIDLLTGGHKHFLGDAYWKDALRKIPD LPVKGRLVYWYLRFLKQNGRTEELNSWLKSYYRYIPGSYYTRVIREEFQEEISSFPLPSNPTWNKDNLFEYLSLTAGIPE LSGKILGKDLDFATQAAAFQLNVRIDDAHSTIRGNRYLQSAKEYLEVGEMAYALSLVQRYKVRQGIGENEKEEILAALGE QTGTPYLTVFYTRSLMKKEKLSDDVILLPSKLAARIYPRPHRGLVTSVSQNVGIEEDIVYAIMRQESFFKENATSISNAR GLMQIMGPTGKEIAKRMNLDSYSLFDPEVSIEMGARFLRYLVASNGNSLQWASIAYNGGPGNLRKWKRNHYRGDFNHFLE ELPIKEPRDYCRIVSSNYYNYQNLRKYKNL >Mature_750_residues MKKFALTSLLLFIFGNLYANDDLKYLIKSYSLQKIHRIFRERHPGTESETYALIRYHEEHPNGSRDKKFAYLVSLLKGKI VLSPGRQDLLEILHSPLPSTSAITKLSLWKLYEESAHRKILGRGELIDLLKKFPRENDPLSQNAISEIFRIYYEAGMIQE CLEFVKSFSDREKSEIFSPMILYRYAKSLYKSGDTEKAEAIFYSILEDSSVFSSVKKFIQVDLQIWKGNSFYTSLTPERA ALFLPHLDSSERKHLILSKDLKKVSFSKGEAFRNTARALITLEPEVLPDFFKRNANLAKSNPYFTAAISRELTNRNLSGK ALNLLNDVNPEKNEEVLYSYARAYKKRGNKNLYFRNLIDSLEKSPTNLIRQDELIDLLTGGHKHFLGDAYWKDALRKIPD LPVKGRLVYWYLRFLKQNGRTEELNSWLKSYYRYIPGSYYTRVIREEFQEEISSFPLPSNPTWNKDNLFEYLSLTAGIPE LSGKILGKDLDFATQAAAFQLNVRIDDAHSTIRGNRYLQSAKEYLEVGEMAYALSLVQRYKVRQGIGENEKEEILAALGE QTGTPYLTVFYTRSLMKKEKLSDDVILLPSKLAARIYPRPHRGLVTSVSQNVGIEEDIVYAIMRQESFFKENATSISNAR GLMQIMGPTGKEIAKRMNLDSYSLFDPEVSIEMGARFLRYLVASNGNSLQWASIAYNGGPGNLRKWKRNHYRGDFNHFLE ELPIKEPRDYCRIVSSNYYNYQNLRKYKNL
Specific function: Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N- acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division [H]
COG id: COG0741
COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)
Gene ontology:
Cell location: Periplasm. Note=Tightly associated with the murein sacculus (By similarity) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the transglycosylase slt family [H]
Homologues:
Organism=Escherichia coli, GI87082441, Length=152, Percent_Identity=34.8684210526316, Blast_Score=82, Evalue=2e-16,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR016026 - InterPro: IPR008258 - InterPro: IPR012289 - InterPro: IPR008939 - InterPro: IPR000189 [H]
Pfam domain/function: PF01464 SLT [H]
EC number: 3.2.1.- [C]
Molecular weight: Translated: 86751; Mature: 86751
Theoretical pI: Translated: 9.70; Mature: 9.70
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 1.3 %Met (Translated Protein) 1.6 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 1.3 %Met (Mature Protein) 1.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKKFALTSLLLFIFGNLYANDDLKYLIKSYSLQKIHRIFRERHPGTESETYALIRYHEEH CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCC PNGSRDKKFAYLVSLLKGKIVLSPGRQDLLEILHSPLPSTSAITKLSLWKLYEESAHRKI CCCCCHHHHHHHHHHHHCCEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH LGRGELIDLLKKFPRENDPLSQNAISEIFRIYYEAGMIQECLEFVKSFSDREKSEIFSPM HCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH ILYRYAKSLYKSGDTEKAEAIFYSILEDSSVFSSVKKFIQVDLQIWKGNSFYTSLTPERA HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEECCCCCHH ALFLPHLDSSERKHLILSKDLKKVSFSKGEAFRNTARALITLEPEVLPDFFKRNANLAKS EEEECCCCCCCCCEEHHHHHHHHHHCCCCHHHHHHHHEEEEECHHHHHHHHHCCCCCCCC NPYFTAAISRELTNRNLSGKALNLLNDVNPEKNEEVLYSYARAYKKRGNKNLYFRNLIDS CCCEEHHHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHH LEKSPTNLIRQDELIDLLTGGHKHFLGDAYWKDALRKIPDLPVKGRLVYWYLRFLKQNGR HHCCHHHHHHHHHHHHHHHCCCHHHHCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCC TEELNSWLKSYYRYIPGSYYTRVIREEFQEEISSFPLPSNPTWNKDNLFEYLSLTAGIPE HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCHH LSGKILGKDLDFATQAAAFQLNVRIDDAHSTIRGNRYLQSAKEYLEVGEMAYALSLVQRY HCCHHHCCCCCHHHHHEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH KVRQGIGENEKEEILAALGEQTGTPYLTVFYTRSLMKKEKLSDDVILLPSKLAARIYPRP HHHHCCCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCEEEECHHHHHHCCCCC HRGLVTSVSQNVGIEEDIVYAIMRQESFFKENATSISNARGLMQIMGPTGKEIAKRMNLD CCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCC SYSLFDPEVSIEMGARFLRYLVASNGNSLQWASIAYNGGPGNLRKWKRNHYRGDFNHFLE CCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHHCCCCHHHHHHH ELPIKEPRDYCRIVSSNYYNYQNLRKYKNL HCCCCCCHHHHHHHHCCCCCHHHHHHHCCC >Mature Secondary Structure MKKFALTSLLLFIFGNLYANDDLKYLIKSYSLQKIHRIFRERHPGTESETYALIRYHEEH CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCC PNGSRDKKFAYLVSLLKGKIVLSPGRQDLLEILHSPLPSTSAITKLSLWKLYEESAHRKI CCCCCHHHHHHHHHHHHCCEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH LGRGELIDLLKKFPRENDPLSQNAISEIFRIYYEAGMIQECLEFVKSFSDREKSEIFSPM HCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH ILYRYAKSLYKSGDTEKAEAIFYSILEDSSVFSSVKKFIQVDLQIWKGNSFYTSLTPERA HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEECCCCCHH ALFLPHLDSSERKHLILSKDLKKVSFSKGEAFRNTARALITLEPEVLPDFFKRNANLAKS EEEECCCCCCCCCEEHHHHHHHHHHCCCCHHHHHHHHEEEEECHHHHHHHHHCCCCCCCC NPYFTAAISRELTNRNLSGKALNLLNDVNPEKNEEVLYSYARAYKKRGNKNLYFRNLIDS CCCEEHHHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHH LEKSPTNLIRQDELIDLLTGGHKHFLGDAYWKDALRKIPDLPVKGRLVYWYLRFLKQNGR HHCCHHHHHHHHHHHHHHHCCCHHHHCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCC TEELNSWLKSYYRYIPGSYYTRVIREEFQEEISSFPLPSNPTWNKDNLFEYLSLTAGIPE HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCHH LSGKILGKDLDFATQAAAFQLNVRIDDAHSTIRGNRYLQSAKEYLEVGEMAYALSLVQRY HCCHHHCCCCCHHHHHEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH KVRQGIGENEKEEILAALGEQTGTPYLTVFYTRSLMKKEKLSDDVILLPSKLAARIYPRP HHHHCCCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCEEEECHHHHHHCCCCC HRGLVTSVSQNVGIEEDIVYAIMRQESFFKENATSISNARGLMQIMGPTGKEIAKRMNLD CCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCC SYSLFDPEVSIEMGARFLRYLVASNGNSLQWASIAYNGGPGNLRKWKRNHYRGDFNHFLE CCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHHCCCCHHHHHHH ELPIKEPRDYCRIVSSNYYNYQNLRKYKNL HCCCCCCHHHHHHHHCCCCCHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]
Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]
General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]