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The map label for this gene is gltA-1 [H]

Identifier: 116328935

GI number: 116328935

Start: 2755489

End: 2756778

Strand: Direct

Name: gltA-1 [H]

Synonym: LBL_2331

Alternate gene names: 116328935

Gene position: 2755489-2756778 (Clockwise)

Preceding gene: 116328934

Following gene: 116328936

Centisome position: 76.24

GC content: 45.89

Gene sequence:

>1290_bases
ATGGCAGAGGTAGCAATTCTGAAAATCAACGGGAAGGAATACGAACTCCCGATCATCGTAGGTACCGAAAACGAAAAAGC
AATCGATATTTCAAAACTTCGTCAACAGACAGGATATGTAACCCTGGACAACGGATACCTAAACACGGGAGCCTGTACTA
GCGCGGTGACTTTTCTCGACGGAGAACTCGGCATATTAAGGTACAGAGGAATTCCAATCGAACAACTTGCGGAAAGTTCC
ACATTTACCGAAGTGGCCTATCTATTGATTTACGGAAAACTTCCGTCGGACACGGAGCTAAAGACGTGGAACGACGAGCT
TACGATGCACACTCTCATTCACGAGGATCTCAAACGTCTCTACAACGGATTCCCGAAAGACGGTCATCCGATGGCAATCA
TGTCCTCTATGATAGGCTCTCTTTCCACTTACTATCAGGATTCTTATGATCCCGAAAACGCGGAACACAGACATATTTCC
ATGATCCGTCTTCTCGCAAAATTCCCTACAATCGCCGCATTCGCCTATAAAAAATCGATCGGACAACCTACGATCCATCC
TTTAAACAGTCTCGACTATTGCGCGAACTTCATGAACATGATGTTCTCCGTCCCTAGCGAAGACTACAAAATCGATCCAG
AAATCGTAAAGGCGCTCAACTTATTATTGATCCTTCACGCCGATCACGAACAAAACTGTTCTACGTCTACGGTGCGTTTG
GTGGGTTCCTCTCTTGCAAATTTATACGGTGCGATATCCGCGGGCATCTGCGCTCTCTGGGGGCCAAGACACGGTGGAGC
AAACCAAGAAGTATTGGAAATGCTCCAAGAGATTCAAGCAAGCGGCCTGCCGGTTAAAAAGATCGTGGAAAAAGCGAAGG
ATAAAAACGATTCTTTTCGTCTTTCCGGATTTGGCCACAGGGTTTATAAGAATTTTGATCCAAGGGCAAAGATTATCAAA
AAGGCTTGCGACTCCGTATTAAAAAGGCTCGGAGTTCAAGATTCTTTATTAGATATTGCTAAAGAACTCGAAGAAACCGC
CCTTCACGATCCTTACTTCGTGGAAAGAAAACTCTATCCGAACGTAGACTTCTATTCCGGAATCATCTATCGCGCACTTG
GAATCCCCGTGAACATGTTCACGGTGATGTTCGCGATGGGTCGCCTTCCCGGTTGGATCGCTCAGTGGAAGGAAATGATT
GAATCGACCGATATGAAAATCGGTCGTCCAAGACAGATCTACACAGGCGCCACCGAAACTTCCTACAAAGAGGCCAAGAA
ACAAACCTGA

Upstream 100 bases:

>100_bases
AACGGAAGGAATAGGATAGGAATCTGAAACGATTTAGAACGCAATTTTTGAACGATTGATAACTTGGTAAAAACAACAAA
CATACTTTTAGGAGAAAAAC

Downstream 100 bases:

>100_bases
ACCTTCCTATGACAAACTTCCGGTTTCGCAGATACCAGCTGAACCGGAAAAGCGAACTTTCCATCCGACGTAAACATCCC
TGGATCTTTAGCGGAAATCT

Product: citrate (Si)-synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MAEVAILKINGKEYELPIIVGTENEKAIDISKLRQQTGYVTLDNGYLNTGACTSAVTFLDGELGILRYRGIPIEQLAESS
TFTEVAYLLIYGKLPSDTELKTWNDELTMHTLIHEDLKRLYNGFPKDGHPMAIMSSMIGSLSTYYQDSYDPENAEHRHIS
MIRLLAKFPTIAAFAYKKSIGQPTIHPLNSLDYCANFMNMMFSVPSEDYKIDPEIVKALNLLLILHADHEQNCSTSTVRL
VGSSLANLYGAISAGICALWGPRHGGANQEVLEMLQEIQASGLPVKKIVEKAKDKNDSFRLSGFGHRVYKNFDPRAKIIK
KACDSVLKRLGVQDSLLDIAKELEETALHDPYFVERKLYPNVDFYSGIIYRALGIPVNMFTVMFAMGRLPGWIAQWKEMI
ESTDMKIGRPRQIYTGATETSYKEAKKQT

Sequences:

>Translated_429_residues
MAEVAILKINGKEYELPIIVGTENEKAIDISKLRQQTGYVTLDNGYLNTGACTSAVTFLDGELGILRYRGIPIEQLAESS
TFTEVAYLLIYGKLPSDTELKTWNDELTMHTLIHEDLKRLYNGFPKDGHPMAIMSSMIGSLSTYYQDSYDPENAEHRHIS
MIRLLAKFPTIAAFAYKKSIGQPTIHPLNSLDYCANFMNMMFSVPSEDYKIDPEIVKALNLLLILHADHEQNCSTSTVRL
VGSSLANLYGAISAGICALWGPRHGGANQEVLEMLQEIQASGLPVKKIVEKAKDKNDSFRLSGFGHRVYKNFDPRAKIIK
KACDSVLKRLGVQDSLLDIAKELEETALHDPYFVERKLYPNVDFYSGIIYRALGIPVNMFTVMFAMGRLPGWIAQWKEMI
ESTDMKIGRPRQIYTGATETSYKEAKKQT
>Mature_428_residues
AEVAILKINGKEYELPIIVGTENEKAIDISKLRQQTGYVTLDNGYLNTGACTSAVTFLDGELGILRYRGIPIEQLAESST
FTEVAYLLIYGKLPSDTELKTWNDELTMHTLIHEDLKRLYNGFPKDGHPMAIMSSMIGSLSTYYQDSYDPENAEHRHISM
IRLLAKFPTIAAFAYKKSIGQPTIHPLNSLDYCANFMNMMFSVPSEDYKIDPEIVKALNLLLILHADHEQNCSTSTVRLV
GSSLANLYGAISAGICALWGPRHGGANQEVLEMLQEIQASGLPVKKIVEKAKDKNDSFRLSGFGHRVYKNFDPRAKIIKK
ACDSVLKRLGVQDSLLDIAKELEETALHDPYFVERKLYPNVDFYSGIIYRALGIPVNMFTVMFAMGRLPGWIAQWKEMIE
STDMKIGRPRQIYTGATETSYKEAKKQT

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0372

COG function: function code C; Citrate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the citrate synthase family [H]

Homologues:

Organism=Homo sapiens, GI38327625, Length=432, Percent_Identity=27.0833333333333, Blast_Score=113, Evalue=3e-25,
Organism=Escherichia coli, GI1786939, Length=425, Percent_Identity=52.9411764705882, Blast_Score=474, Evalue=1e-135,
Organism=Escherichia coli, GI1786527, Length=382, Percent_Identity=30.8900523560209, Blast_Score=165, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI17555174, Length=411, Percent_Identity=27.007299270073, Blast_Score=113, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6324328, Length=436, Percent_Identity=28.6697247706422, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6319850, Length=403, Percent_Identity=29.5285359801489, Blast_Score=113, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6325257, Length=408, Percent_Identity=25.9803921568627, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24640126, Length=453, Percent_Identity=27.1523178807947, Blast_Score=122, Evalue=7e-28,
Organism=Drosophila melanogaster, GI24640124, Length=453, Percent_Identity=27.1523178807947, Blast_Score=121, Evalue=7e-28,
Organism=Drosophila melanogaster, GI21356863, Length=367, Percent_Identity=25.6130790190736, Blast_Score=101, Evalue=1e-21,

Paralogues:

None

Copy number: 624 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016142
- InterPro:   IPR016143
- InterPro:   IPR002020
- InterPro:   IPR016141
- InterPro:   IPR019810
- InterPro:   IPR010953 [H]

Pfam domain/function: PF00285 Citrate_synt [H]

EC number: =2.3.3.1 [H]

Molecular weight: Translated: 48201; Mature: 48070

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS00480 CITRATE_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEVAILKINGKEYELPIIVGTENEKAIDISKLRQQTGYVTLDNGYLNTGACTSAVTFLD
CCCEEEEEECCCEEEEEEEEECCCCCCCCHHHHHHHCCEEEECCCCCCCCHHHHHHHHCC
GELGILRYRGIPIEQLAESSTFTEVAYLLIYGKLPSDTELKTWNDELTMHTLIHEDLKRL
CCCCEEEECCCCHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
YNGFPKDGHPMAIMSSMIGSLSTYYQDSYDPENAEHRHISMIRLLAKFPTIAAFAYKKSI
HCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHC
GQPTIHPLNSLDYCANFMNMMFSVPSEDYKIDPEIVKALNLLLILHADHEQNCSTSTVRL
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHEEEECCCCCCCCHHHHHH
VGSSLANLYGAISAGICALWGPRHGGANQEVLEMLQEIQASGLPVKKIVEKAKDKNDSFR
HHHHHHHHHHHHHHCHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEE
LSGFGHRVYKNFDPRAKIIKKACDSVLKRLGVQDSLLDIAKELEETALHDPYFVERKLYP
EECCCHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEHHCCCC
NVDFYSGIIYRALGIPVNMFTVMFAMGRLPGWIAQWKEMIESTDMKIGRPRQIYTGATET
CCHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCH
SYKEAKKQT
HHHHHHCCC
>Mature Secondary Structure 
AEVAILKINGKEYELPIIVGTENEKAIDISKLRQQTGYVTLDNGYLNTGACTSAVTFLD
CCEEEEEECCCEEEEEEEEECCCCCCCCHHHHHHHCCEEEECCCCCCCCHHHHHHHHCC
GELGILRYRGIPIEQLAESSTFTEVAYLLIYGKLPSDTELKTWNDELTMHTLIHEDLKRL
CCCCEEEECCCCHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
YNGFPKDGHPMAIMSSMIGSLSTYYQDSYDPENAEHRHISMIRLLAKFPTIAAFAYKKSI
HCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHC
GQPTIHPLNSLDYCANFMNMMFSVPSEDYKIDPEIVKALNLLLILHADHEQNCSTSTVRL
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHEEEECCCCCCCCHHHHHH
VGSSLANLYGAISAGICALWGPRHGGANQEVLEMLQEIQASGLPVKKIVEKAKDKNDSFR
HHHHHHHHHHHHHHCHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEE
LSGFGHRVYKNFDPRAKIIKKACDSVLKRLGVQDSLLDIAKELEETALHDPYFVERKLYP
EECCCHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEHHCCCC
NVDFYSGIIYRALGIPVNMFTVMFAMGRLPGWIAQWKEMIESTDMKIGRPRQIYTGATET
CCHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCH
SYKEAKKQT
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]