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The map label for this gene is degQ [C]

Identifier: 116328924

GI number: 116328924

Start: 2742693

End: 2743859

Strand: Reverse

Name: degQ [C]

Synonym: LBL_2318

Alternate gene names: 116328924

Gene position: 2743859-2742693 (Counterclockwise)

Preceding gene: 116328925

Following gene: 116328923

Centisome position: 75.91

GC content: 47.56

Gene sequence:

>1167_bases
ATGAAAAACATGGAAAAACTGAAGTATGTTGCAATCGTAAGCATTTCACTTCTGCTCGGAGCGTTCTTATCTCCCGTCAT
GTTTTGTGGAACCGGTCGAAGCAATCCTCTTTTTTTAAACGCTAAAGGTGATAAGGAACCTAGTCCGGCGACTCGTCAGG
CGATCACGATTCAACAAGCCTTTGAGGAAGTTTATCAAACCGCTTCTCCAAGTGTAGTTTCCATCGCTACGGAAAAAATT
CAAAACGTTCCCGTTCATTCCGGGCCTTTCGGAGATCCTTTCTTCGATCAATTCTTCGGCAGAGGTCAAGGCGGAAGCGG
AAGAGTGATGAAACAAAAACAAACTGGGCTCGGTTCCGGGATTATTCTCAATACTCAGGGATATATTTTAACCAACGAAC
ATGTGGTTCGTTCCATGGATAAACTTACCGTTCGTTTAAAAACGGGTAAGACATTTAACGCGGAACTCGTCGGCTCTGAT
CCTGTGATTGATTTGGCTCTTTTAAAAATCAAGCCGGGCGGTGAAATTGTTCCGATCGAACTCGGAGATTCTTCCGCGGT
AAAAGTCGGGGACTGGGCGATTGCAATCGGGGCCCCTCTGGGTTACGAACAGTCTCTGACCGCGGGGGTTGTCAGCGCTG
TCGGTAGAACCGGAATCGATAACAGTGGAGTTCATTATCTTCAAACGGACGCTTCCATCAATCAGGGGAATTCCGGCGGT
CCTCTTCTCGATATCAACGGTCGTGTGATCGGTATCAATCGTATGATCGCTTCTCAGAGCGGGGGTTCGGTGGGAATCGG
ATTTGCGATTCCGATTAACGAAGCGAAAGCGATCATGGAAGAATTAAAAACCACCGGTAAGGTCAAACGTCCCGCACAGC
CTTGGCTTGGAGTCGGAGTGGATTATCTTCATGAAGAGGACGCGAAGAAGTTGAATATTTCGGGCGGTGCGGTTGTCGTT
CAGATCATGAATGATTCTCCGGCGGATCGTGCTGGAATTCAGCTGATGGATGTGATCACTGAGATTTCCGGAACTAAAAT
CAATTCTCCGGAGGAAGTGGTCAGCACGGTTAAGAAGAGTAAGGTGGGTGATCGTATCACGGTTACGGTTATGCGTCAGG
GAAACGTTTCTAGAATTTCGATCCAGCTTAAGGAAAGACCGAACTGA

Upstream 100 bases:

>100_bases
TCTCTAAGGACTGGCTTTCAAATCTAACTTGACAGTCATAAAAGCGAGTCGATTCTTTTAGTTACCAAATGGAAATTGAT
TTTCAGAGGGATAGAATTCA

Downstream 100 bases:

>100_bases
TTGGCAAAATCCCATACGCTTAATCCTGAGGAAGAATTTGAAGAAGAGTCGGGTTTACGTCCTTCTCTTCTTTCCGAATT
TATAGGTCAGAAGGAAGTTC

Product: trypsin-like serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MKNMEKLKYVAIVSISLLLGAFLSPVMFCGTGRSNPLFLNAKGDKEPSPATRQAITIQQAFEEVYQTASPSVVSIATEKI
QNVPVHSGPFGDPFFDQFFGRGQGGSGRVMKQKQTGLGSGIILNTQGYILTNEHVVRSMDKLTVRLKTGKTFNAELVGSD
PVIDLALLKIKPGGEIVPIELGDSSAVKVGDWAIAIGAPLGYEQSLTAGVVSAVGRTGIDNSGVHYLQTDASINQGNSGG
PLLDINGRVIGINRMIASQSGGSVGIGFAIPINEAKAIMEELKTTGKVKRPAQPWLGVGVDYLHEEDAKKLNISGGAVVV
QIMNDSPADRAGIQLMDVITEISGTKINSPEEVVSTVKKSKVGDRITVTVMRQGNVSRISIQLKERPN

Sequences:

>Translated_388_residues
MKNMEKLKYVAIVSISLLLGAFLSPVMFCGTGRSNPLFLNAKGDKEPSPATRQAITIQQAFEEVYQTASPSVVSIATEKI
QNVPVHSGPFGDPFFDQFFGRGQGGSGRVMKQKQTGLGSGIILNTQGYILTNEHVVRSMDKLTVRLKTGKTFNAELVGSD
PVIDLALLKIKPGGEIVPIELGDSSAVKVGDWAIAIGAPLGYEQSLTAGVVSAVGRTGIDNSGVHYLQTDASINQGNSGG
PLLDINGRVIGINRMIASQSGGSVGIGFAIPINEAKAIMEELKTTGKVKRPAQPWLGVGVDYLHEEDAKKLNISGGAVVV
QIMNDSPADRAGIQLMDVITEISGTKINSPEEVVSTVKKSKVGDRITVTVMRQGNVSRISIQLKERPN
>Mature_388_residues
MKNMEKLKYVAIVSISLLLGAFLSPVMFCGTGRSNPLFLNAKGDKEPSPATRQAITIQQAFEEVYQTASPSVVSIATEKI
QNVPVHSGPFGDPFFDQFFGRGQGGSGRVMKQKQTGLGSGIILNTQGYILTNEHVVRSMDKLTVRLKTGKTFNAELVGSD
PVIDLALLKIKPGGEIVPIELGDSSAVKVGDWAIAIGAPLGYEQSLTAGVVSAVGRTGIDNSGVHYLQTDASINQGNSGG
PLLDINGRVIGINRMIASQSGGSVGIGFAIPINEAKAIMEELKTTGKVKRPAQPWLGVGVDYLHEEDAKKLNISGGAVVV
QIMNDSPADRAGIQLMDVITEISGTKINSPEEVVSTVKKSKVGDRITVTVMRQGNVSRISIQLKERPN

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=273, Percent_Identity=34.4322344322344, Blast_Score=149, Evalue=6e-36,
Organism=Homo sapiens, GI24308541, Length=291, Percent_Identity=31.9587628865979, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI22129776, Length=258, Percent_Identity=32.5581395348837, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI7019477, Length=256, Percent_Identity=32.03125, Blast_Score=124, Evalue=1e-28,
Organism=Escherichia coli, GI1789629, Length=323, Percent_Identity=38.0804953560372, Blast_Score=207, Evalue=7e-55,
Organism=Escherichia coli, GI1786356, Length=357, Percent_Identity=37.8151260504202, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI1789630, Length=389, Percent_Identity=32.9048843187661, Blast_Score=165, Evalue=5e-42,
Organism=Drosophila melanogaster, GI24646839, Length=282, Percent_Identity=34.7517730496454, Blast_Score=143, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 41165; Mature: 41165

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNMEKLKYVAIVSISLLLGAFLSPVMFCGTGRSNPLFLNAKGDKEPSPATRQAITIQQA
CCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHH
FEEVYQTASPSVVSIATEKIQNVPVHSGPFGDPFFDQFFGRGQGGSGRVMKQKQTGLGSG
HHHHHHCCCCCEEEEEHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCEEEHHHCCCCCC
IILNTQGYILTNEHVVRSMDKLTVRLKTGKTFNAELVGSDPVIDLALLKIKPGGEIVPIE
EEEECCCEEEECHHHHHHHHHEEEEEECCCEECEEECCCCCCEEEEEEEECCCCCEEEEE
LGDSSAVKVGDWAIAIGAPLGYEQSLTAGVVSAVGRTGIDNSGVHYLQTDASINQGNSGG
ECCCCCEEECCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCC
PLLDINGRVIGINRMIASQSGGSVGIGFAIPINEAKAIMEELKTTGKVKRPAQPWLGVGV
CEEEECCEEEEEEEEEECCCCCCEEEEEEEECHHHHHHHHHHHHCCCCCCCCCCCHHCCH
DYLHEEDAKKLNISGGAVVVQIMNDSPADRAGIQLMDVITEISGTKINSPEEVVSTVKKS
HHHCCCCCCEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
KVGDRITVTVMRQGNVSRISIQLKERPN
CCCCEEEEEEEECCCEEEEEEEEECCCC
>Mature Secondary Structure
MKNMEKLKYVAIVSISLLLGAFLSPVMFCGTGRSNPLFLNAKGDKEPSPATRQAITIQQA
CCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHH
FEEVYQTASPSVVSIATEKIQNVPVHSGPFGDPFFDQFFGRGQGGSGRVMKQKQTGLGSG
HHHHHHCCCCCEEEEEHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCEEEHHHCCCCCC
IILNTQGYILTNEHVVRSMDKLTVRLKTGKTFNAELVGSDPVIDLALLKIKPGGEIVPIE
EEEECCCEEEECHHHHHHHHHEEEEEECCCEECEEECCCCCCEEEEEEEECCCCCEEEEE
LGDSSAVKVGDWAIAIGAPLGYEQSLTAGVVSAVGRTGIDNSGVHYLQTDASINQGNSGG
ECCCCCEEECCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCC
PLLDINGRVIGINRMIASQSGGSVGIGFAIPINEAKAIMEELKTTGKVKRPAQPWLGVGV
CEEEECCEEEEEEEEEECCCCCCEEEEEEEECHHHHHHHHHHHHCCCCCCCCCCCHHCCH
DYLHEEDAKKLNISGGAVVVQIMNDSPADRAGIQLMDVITEISGTKINSPEEVVSTVKKS
HHHCCCCCCEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
KVGDRITVTVMRQGNVSRISIQLKERPN
CCCCEEEEEEEECCCEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]