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The map label for this gene is prmA

Identifier: 116328843

GI number: 116328843

Start: 2620201

End: 2621103

Strand: Reverse

Name: prmA

Synonym: LBL_2224

Alternate gene names: 116328843

Gene position: 2621103-2620201 (Counterclockwise)

Preceding gene: 116328844

Following gene: 116328842

Centisome position: 72.52

GC content: 44.63

Gene sequence:

>903_bases
TTGAAATACAGAGAAATCATTTTAAACATCCCTAAAGAAATCGCGGAGGACTTCACTACTTTTTTAGATGAGATAGGAGT
TGCGGGATATTACGAGATCCTGTTTGACCGAGAAGTTCCGCGCGCTCCACACGAAGAAATCATTTCGGACGATACGAAGT
TCCGTGTTTATCTCGCGCAAGAAGACAACGAGAACGAAACCAAAATTCTCATCTATCTAAAAGCGAATGCGGGTGAAGTT
TTCTTTTCGGAGTCCAGATGGATCGAAACCAAAGAATACGAGGAAGCTTATAAAGAATTTTATAAACCTTTTATCGTGGG
TTCCTATCGAGTGATTCCCACTTGGGAAAAAGACACCGCGTTAGGCACAACTCCCGAAGGGATTTTCCCTTTGTTCATCA
ATCCTGGACTTGCATTTGGAACCGGACATCACGAGACGACCCGTCTTGTTTTGGGAAGAATGGGGAACTTGAGTCTTTCC
GGTAAAAAGGTTGTGGACGTTGGAACCGGTTCCGGGATTTTGAGCGTTGCCGCGGCGAAGTCGGGAGCTTCCCCGATTTT
AGCGGTGGATGTGGATCCGAACAGCGTGAGATCCGCCTCTTTCAATCGGGATGAAAACGATATTTCCTCGGAAGTTTTAG
CCGTGGAAGAGGGCGGTTTCGATCATGAAAAGATCCAAGGACAAACATGGGATCTTTTAATCGCCAATATCACGTTTGCC
GTATTAAAAGCGAATATTCAAAAAATTGTATCTATTAAGACCGATCATTTTCTGTTCAGCGGAGTCATCACCGAACGGTT
GGAGGAATTTTTGGAACTTCTGAAAAACGAGGTGGGCGGCGAAGGAGTTTTCTTTCAGGAAGACACGGGCTGGGAATTGA
TCGAATGGAAAAGAAAAGGATAA

Upstream 100 bases:

>100_bases
TTTGGATCGTAAAAGACTTTCGGGCTTTCGTCCTAAAGGATGAAAACCAAAGTGACACCGTGGTTGATGCTGAAATTCTG
GATGAGACCTGAGAAACGAT

Downstream 100 bases:

>100_bases
ATCGATGAAACACTACGACGTATTCGGAGTCGGCAACGCACTCGTGGATATTTTAGTTCCTACGGAGGACGTTTTTATCA
AACGTTTAGGATTTGAGAAA

Product: ribosomal protein L11 methylase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MKYREIILNIPKEIAEDFTTFLDEIGVAGYYEILFDREVPRAPHEEIISDDTKFRVYLAQEDNENETKILIYLKANAGEV
FFSESRWIETKEYEEAYKEFYKPFIVGSYRVIPTWEKDTALGTTPEGIFPLFINPGLAFGTGHHETTRLVLGRMGNLSLS
GKKVVDVGTGSGILSVAAAKSGASPILAVDVDPNSVRSASFNRDENDISSEVLAVEEGGFDHEKIQGQTWDLLIANITFA
VLKANIQKIVSIKTDHFLFSGVITERLEEFLELLKNEVGGEGVFFQEDTGWELIEWKRKG

Sequences:

>Translated_300_residues
MKYREIILNIPKEIAEDFTTFLDEIGVAGYYEILFDREVPRAPHEEIISDDTKFRVYLAQEDNENETKILIYLKANAGEV
FFSESRWIETKEYEEAYKEFYKPFIVGSYRVIPTWEKDTALGTTPEGIFPLFINPGLAFGTGHHETTRLVLGRMGNLSLS
GKKVVDVGTGSGILSVAAAKSGASPILAVDVDPNSVRSASFNRDENDISSEVLAVEEGGFDHEKIQGQTWDLLIANITFA
VLKANIQKIVSIKTDHFLFSGVITERLEEFLELLKNEVGGEGVFFQEDTGWELIEWKRKG
>Mature_300_residues
MKYREIILNIPKEIAEDFTTFLDEIGVAGYYEILFDREVPRAPHEEIISDDTKFRVYLAQEDNENETKILIYLKANAGEV
FFSESRWIETKEYEEAYKEFYKPFIVGSYRVIPTWEKDTALGTTPEGIFPLFINPGLAFGTGHHETTRLVLGRMGNLSLS
GKKVVDVGTGSGILSVAAAKSGASPILAVDVDPNSVRSASFNRDENDISSEVLAVEEGGFDHEKIQGQTWDLLIANITFA
VLKANIQKIVSIKTDHFLFSGVITERLEEFLELLKNEVGGEGVFFQEDTGWELIEWKRKG

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=246, Percent_Identity=28.4552845528455, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_LEPBJ (Q04QV8)

Other databases:

- EMBL:   CP000350
- RefSeq:   YP_801470.1
- ProteinModelPortal:   Q04QV8
- SMR:   Q04QV8
- STRING:   Q04QV8
- GeneID:   4411434
- GenomeReviews:   CP000350_GR
- KEGG:   lbj:LBJ_2231
- eggNOG:   COG2264
- HOGENOM:   HBG527716
- OMA:   MEVAKEN
- PhylomeDB:   Q04QV8
- ProtClustDB:   CLSK573891
- BioCyc:   LBOR355277:LBJ_2231-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 33743; Mature: 33743

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYREIILNIPKEIAEDFTTFLDEIGVAGYYEILFDREVPRAPHEEIISDDTKFRVYLAQ
CCHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHCCCCEEEEEEEE
EDNENETKILIYLKANAGEVFFSESRWIETKEYEEAYKEFYKPFIVGSYRVIPTWEKDTA
CCCCCCEEEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHCCCCEECCEEEEECCCCCCC
LGTTPEGIFPLFINPGLAFGTGHHETTRLVLGRMGNLSLSGKKVVDVGTGSGILSVAAAK
CCCCCCCEEEEEECCCEEECCCCCHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEEEECC
SGASPILAVDVDPNSVRSASFNRDENDISSEVLAVEEGGFDHEKIQGQTWDLLIANITFA
CCCCCEEEEECCCCCCCCCCCCCCCCHHHHEEEEEECCCCCHHHHCCCCCEEHHHHHHHH
VLKANIQKIVSIKTDHFLFSGVITERLEEFLELLKNEVGGEGVFFQEDTGWELIEWKRKG
HHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEECCC
>Mature Secondary Structure
MKYREIILNIPKEIAEDFTTFLDEIGVAGYYEILFDREVPRAPHEEIISDDTKFRVYLAQ
CCHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHCCCCEEEEEEEE
EDNENETKILIYLKANAGEVFFSESRWIETKEYEEAYKEFYKPFIVGSYRVIPTWEKDTA
CCCCCCEEEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHCCCCEECCEEEEECCCCCCC
LGTTPEGIFPLFINPGLAFGTGHHETTRLVLGRMGNLSLSGKKVVDVGTGSGILSVAAAK
CCCCCCCEEEEEECCCEEECCCCCHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEEEECC
SGASPILAVDVDPNSVRSASFNRDENDISSEVLAVEEGGFDHEKIQGQTWDLLIANITFA
CCCCCEEEEECCCCCCCCCCCCCCCCHHHHEEEEEECCCCCHHHHCCCCCEEHHHHHHHH
VLKANIQKIVSIKTDHFLFSGVITERLEEFLELLKNEVGGEGVFFQEDTGWELIEWKRKG
HHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA