Click here to switch to the map view.

The map label for this gene is yegV [C]

Identifier: 116328842

GI number: 116328842

Start: 2619210

End: 2620196

Strand: Reverse

Name: yegV [C]

Synonym: LBL_2223

Alternate gene names: 116328842

Gene position: 2620196-2619210 (Counterclockwise)

Preceding gene: 116328843

Following gene: 116328839

Centisome position: 72.49

GC content: 46.1

Gene sequence:

>987_bases
ATGAAACACTACGACGTATTCGGAGTCGGCAACGCACTCGTGGATATTTTAGTTCCTACGGAGGACGTTTTTATCAAACG
TTTAGGATTTGAGAAAGGAATCATGACTTTGGTCGATTCCGAAAAACAAGGAGAGGTTTTGACCGCTCTGGAAGGAGGCA
AAAAAGAACTTCGTTCCGGAGGAAGTGCGGCAAATACGATGATTGCACTTGCGAACTCGGGCGGAACCGGAACTTATACC
GGGAAGGTTTCCAAAGACACTTACGGAGAATTTTATAAGAAGGACATGGAAAACGCCGGAATCCTTTTCGACGTCGTTCC
GGAAGACAACGGACATACCGGAACCTGCGTCGTTTTAACCACTCCCGATGCTGAAAGAACGATGCTCACCCACTTGGGGA
TTTCCATCACATTACAAAAATCGGATGTGGATTTGGACAAACTCAAGTCCTCCGGCATTTCCTATATCGAAGGATATCTC
TGGGATGGTCAGGGAACCAAAGAAGCTTCTCTTTTGACGATGGAAGAATCCAAAAGAAACGGGGTAAAAGTCGCTTACAC
ATACAGCGATCCGTTTTGTGTGAATCGTTCGAGAGAAGACTTCGTTCGTTTAACAAAAGATTACTTCGATATCGTTTTCT
GCAACGCGGAAGAAGCCAAAGCCCTTTCTCAAAGGGAAGATAAACTCGAAGCTTTGAAATTCATCGCGAATCTTTCTCCT
CTCGTTTTTATGACCGATTCCGCAAATGGGGCCTATTTTGCGGAGAACGGAGTGGTTGCTCACGTTGGTGGATTCCCTAC
GAAAGCGATCGATACGACCGGTGCAGGTGATTGTTTTGCGGCGGGTGTTCTCTACGGACTGACCCACGGTTTTAGTTTGG
AAAAATCGACCCGTTGGGGAAATTACGTTGCTTCGAGAATTGTCCAGGAAATTGGGCCGAGACTAGGTATAAAATTGATG
GGGCGCCAGGACGAGATTTTAAAATGA

Upstream 100 bases:

>100_bases
TTTTTGGAACTTCTGAAAAACGAGGTGGGCGGCGAAGGAGTTTTCTTTCAGGAAGACACGGGCTGGGAATTGATCGAATG
GAAAAGAAAAGGATAAATCG

Downstream 100 bases:

>100_bases
TTTTTTAATTTGCTGTTTTTCTAATATACTATGAGTTAGTAGAACCACGGTTGGTCGATCGGACTCTCGGTTATAGTCAA
GTTATTAGAGTTTTTGAAAA

Product: sugar kinase

Products: ADP; D-ribose 5-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MKHYDVFGVGNALVDILVPTEDVFIKRLGFEKGIMTLVDSEKQGEVLTALEGGKKELRSGGSAANTMIALANSGGTGTYT
GKVSKDTYGEFYKKDMENAGILFDVVPEDNGHTGTCVVLTTPDAERTMLTHLGISITLQKSDVDLDKLKSSGISYIEGYL
WDGQGTKEASLLTMEESKRNGVKVAYTYSDPFCVNRSREDFVRLTKDYFDIVFCNAEEAKALSQREDKLEALKFIANLSP
LVFMTDSANGAYFAENGVVAHVGGFPTKAIDTTGAGDCFAAGVLYGLTHGFSLEKSTRWGNYVASRIVQEIGPRLGIKLM
GRQDEILK

Sequences:

>Translated_328_residues
MKHYDVFGVGNALVDILVPTEDVFIKRLGFEKGIMTLVDSEKQGEVLTALEGGKKELRSGGSAANTMIALANSGGTGTYT
GKVSKDTYGEFYKKDMENAGILFDVVPEDNGHTGTCVVLTTPDAERTMLTHLGISITLQKSDVDLDKLKSSGISYIEGYL
WDGQGTKEASLLTMEESKRNGVKVAYTYSDPFCVNRSREDFVRLTKDYFDIVFCNAEEAKALSQREDKLEALKFIANLSP
LVFMTDSANGAYFAENGVVAHVGGFPTKAIDTTGAGDCFAAGVLYGLTHGFSLEKSTRWGNYVASRIVQEIGPRLGIKLM
GRQDEILK
>Mature_328_residues
MKHYDVFGVGNALVDILVPTEDVFIKRLGFEKGIMTLVDSEKQGEVLTALEGGKKELRSGGSAANTMIALANSGGTGTYT
GKVSKDTYGEFYKKDMENAGILFDVVPEDNGHTGTCVVLTTPDAERTMLTHLGISITLQKSDVDLDKLKSSGISYIEGYL
WDGQGTKEASLLTMEESKRNGVKVAYTYSDPFCVNRSREDFVRLTKDYFDIVFCNAEEAKALSQREDKLEALKFIANLSP
LVFMTDSANGAYFAENGVVAHVGGFPTKAIDTTGAGDCFAAGVLYGLTHGFSLEKSTRWGNYVASRIVQEIGPRLGIKLM
GRQDEILK

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI32484973, Length=332, Percent_Identity=24.6987951807229, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI32484975, Length=332, Percent_Identity=24.6987951807229, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI87081971, Length=326, Percent_Identity=26.3803680981595, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786684, Length=395, Percent_Identity=23.5443037974684, Blast_Score=66, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322565, Length=330, Percent_Identity=27.8787878787879, Blast_Score=85, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21355521, Length=339, Percent_Identity=25.0737463126844, Blast_Score=89, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: 2.7.1.15

Molecular weight: Translated: 35687; Mature: 35687

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHYDVFGVGNALVDILVPTEDVFIKRLGFEKGIMTLVDSEKQGEVLTALEGGKKELRSG
CCCEEEEECCCEEEEEEECCHHHHHHHHCCCCCCEEEECCCCCCCEEEEECCCHHHHHCC
GSAANTMIALANSGGTGTYTGKVSKDTYGEFYKKDMENAGILFDVVPEDNGHTGTCVVLT
CCCCEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEEE
TPDAERTMLTHLGISITLQKSDVDLDKLKSSGISYIEGYLWDGQGTKEASLLTMEESKRN
CCCCHHHHHHHCCEEEEEECCCCCHHHHHHCCCCEEEEEEECCCCCCCEEEEEEECCCCC
GVKVAYTYSDPFCVNRSREDFVRLTKDYFDIVFCNAEEAKALSQREDKLEALKFIANLSP
CEEEEEEECCCEEECCCHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCC
LVFMTDSANGAYFAENGVVAHVGGFPTKAIDTTGAGDCFAAGVLYGLTHGFSLEKSTRWG
EEEEEECCCCCEEECCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHH
NYVASRIVQEIGPRLGIKLMGRQDEILK
HHHHHHHHHHHCCCCCEEEECCCHHCCC
>Mature Secondary Structure
MKHYDVFGVGNALVDILVPTEDVFIKRLGFEKGIMTLVDSEKQGEVLTALEGGKKELRSG
CCCEEEEECCCEEEEEEECCHHHHHHHHCCCCCCEEEECCCCCCCEEEEECCCHHHHHCC
GSAANTMIALANSGGTGTYTGKVSKDTYGEFYKKDMENAGILFDVVPEDNGHTGTCVVLT
CCCCEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEEE
TPDAERTMLTHLGISITLQKSDVDLDKLKSSGISYIEGYLWDGQGTKEASLLTMEESKRN
CCCCHHHHHHHCCEEEEEECCCCCHHHHHHCCCCEEEEEEECCCCCCCEEEEEEECCCCC
GVKVAYTYSDPFCVNRSREDFVRLTKDYFDIVFCNAEEAKALSQREDKLEALKFIANLSP
CEEEEEEECCCEEECCCHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCC
LVFMTDSANGAYFAENGVVAHVGGFPTKAIDTTGAGDCFAAGVLYGLTHGFSLEKSTRWG
EEEEEECCCCCEEECCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHH
NYVASRIVQEIGPRLGIKLMGRQDEILK
HHHHHHHHHHHCCCCCEEEECCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; D-ribose

Specific reaction: ATP + D-ribose = ADP + D-ribose 5-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]