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The map label for this gene is crt [H]

Identifier: 116328825

GI number: 116328825

Start: 2595872

End: 2596672

Strand: Direct

Name: crt [H]

Synonym: LBL_2204

Alternate gene names: 116328825

Gene position: 2595872-2596672 (Clockwise)

Preceding gene: 116328824

Following gene: 116328827

Centisome position: 71.82

GC content: 40.2

Gene sequence:

>801_bases
ATGGAATTCATTGACCAAGACACAATTGATCTAGGTTCCGGAAACAAGATCTTAAAGTTAAGCCTCAACAATCCTGAAAC
CAGAAATTCTATGACCAGGGAAATGGGTTTGGAATTCAAAAAAATCATCGATGGGTTGATGGAAACAACCGAAAAGAACA
AACCAAGAGTCGTCATTTTAACCGGAAAGAACGATATTTTTTCCGCAGGCGGTAATTTCGAATTATTGAAGTCGCTTTCA
AATAAAGACTATGAAACGAACAAAAAAGCGATGTTCGAATTTTATAACCTTTTCTTATCCGTCAGACGTTTGGACATTCC
GGTAATCTGTGCCGCAAACGGCCACGCAATCGGAGCCGGGCTTTCACTTACATTCGCATGTGATATCCGAGTTTTTGCCA
ATGAGGCTAAATATCAATTTAACTTCGTTAAACTTGGAATCCATCCGGGTATGGGCTCCAGTTATACCGTGAAGGAATTA
TTTGGGACTCATGTCGCAAACCGGCTTTTATTTTTAGCGGAAACCTTCAATGGAGAAGAGGCATTCCGTCTTGGTCTTTG
CAATGACTCGGTTCCACAAAAGGAAGTCTTGGGAAGAGCGACTGAAATCGCAATCGTATTGTCCGAAAGTGCACCTTTAG
CTCTCAGCGAATTAAAGAAGAACACTTACGACAGGGAAAAATTAGAAACCGCCCTTAGAAAAGAAGCAGAATCTCAAGCA
AGAAATTTTATCTCGGCCGATTTCAAAGAAACGATCAAAGCAATCGAACAAAAAAGAAAACCGATCTTCAAAGGATTATA
A

Upstream 100 bases:

>100_bases
TTCTCGAATACTACACCCAGATGGGAATCGGAGAAAAACCGTTGACCGTATCCGACCGAATCTGGTATGAAAGTTTCGAG
TTGGAGAAAAAAGCAGTTTA

Downstream 100 bases:

>100_bases
TCGGTTTTCTTTTGTTTCCTTATCGTAATCCTTTAACGCTTGGAAGGTCGACTCATAGTCGTTCCAAGCATTCCAGATCA
CAAACCCGTTCCCTCCGCTA

Product: enoyl-CoA hydratase/carnithine racemase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MEFIDQDTIDLGSGNKILKLSLNNPETRNSMTREMGLEFKKIIDGLMETTEKNKPRVVILTGKNDIFSAGGNFELLKSLS
NKDYETNKKAMFEFYNLFLSVRRLDIPVICAANGHAIGAGLSLTFACDIRVFANEAKYQFNFVKLGIHPGMGSSYTVKEL
FGTHVANRLLFLAETFNGEEAFRLGLCNDSVPQKEVLGRATEIAIVLSESAPLALSELKKNTYDREKLETALRKEAESQA
RNFISADFKETIKAIEQKRKPIFKGL

Sequences:

>Translated_266_residues
MEFIDQDTIDLGSGNKILKLSLNNPETRNSMTREMGLEFKKIIDGLMETTEKNKPRVVILTGKNDIFSAGGNFELLKSLS
NKDYETNKKAMFEFYNLFLSVRRLDIPVICAANGHAIGAGLSLTFACDIRVFANEAKYQFNFVKLGIHPGMGSSYTVKEL
FGTHVANRLLFLAETFNGEEAFRLGLCNDSVPQKEVLGRATEIAIVLSESAPLALSELKKNTYDREKLETALRKEAESQA
RNFISADFKETIKAIEQKRKPIFKGL
>Mature_266_residues
MEFIDQDTIDLGSGNKILKLSLNNPETRNSMTREMGLEFKKIIDGLMETTEKNKPRVVILTGKNDIFSAGGNFELLKSLS
NKDYETNKKAMFEFYNLFLSVRRLDIPVICAANGHAIGAGLSLTFACDIRVFANEAKYQFNFVKLGIHPGMGSSYTVKEL
FGTHVANRLLFLAETFNGEEAFRLGLCNDSVPQKEVLGRATEIAIVLSESAPLALSELKKNTYDREKLETALRKEAESQA
RNFISADFKETIKAIEQKRKPIFKGL

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI31542718, Length=257, Percent_Identity=27.2373540856031, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI70995211, Length=221, Percent_Identity=27.6018099547511, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI194097323, Length=265, Percent_Identity=23.7735849056604, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI213417737, Length=226, Percent_Identity=26.9911504424779, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI157694516, Length=226, Percent_Identity=27.4336283185841, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI116235487, Length=229, Percent_Identity=26.2008733624454, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI4502327, Length=255, Percent_Identity=27.843137254902, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI221136756, Length=224, Percent_Identity=27.6785714285714, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI221136753, Length=224, Percent_Identity=27.6785714285714, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI221307494, Length=224, Percent_Identity=27.6785714285714, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI260274832, Length=231, Percent_Identity=25.1082251082251, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI45643119, Length=231, Percent_Identity=25.1082251082251, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI260275230, Length=231, Percent_Identity=25.1082251082251, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1787659, Length=255, Percent_Identity=28.2352941176471, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI221142681, Length=267, Percent_Identity=28.0898876404494, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787660, Length=258, Percent_Identity=29.4573643410853, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1788597, Length=256, Percent_Identity=25.390625, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1788682, Length=193, Percent_Identity=27.979274611399, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87082183, Length=267, Percent_Identity=22.8464419475655, Blast_Score=68, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17540714, Length=242, Percent_Identity=31.8181818181818, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17536985, Length=265, Percent_Identity=25.6603773584906, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI25145438, Length=255, Percent_Identity=25.4901960784314, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17554946, Length=256, Percent_Identity=25, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17549921, Length=225, Percent_Identity=26.2222222222222, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17535521, Length=261, Percent_Identity=23.7547892720307, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24653139, Length=261, Percent_Identity=30.2681992337165, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI20129971, Length=255, Percent_Identity=26.2745098039216, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24653477, Length=255, Percent_Identity=26.2745098039216, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI19922422, Length=263, Percent_Identity=26.2357414448669, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI19920382, Length=264, Percent_Identity=25.7575757575758, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24654903, Length=174, Percent_Identity=28.735632183908, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI45550169, Length=264, Percent_Identity=27.6515151515151, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21357171, Length=250, Percent_Identity=24.8, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI19921018, Length=190, Percent_Identity=28.9473684210526, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 29789; Mature: 29789

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFIDQDTIDLGSGNKILKLSLNNPETRNSMTREMGLEFKKIIDGLMETTEKNKPRVVIL
CCCCCCCCEECCCCCEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEE
TGKNDIFSAGGNFELLKSLSNKDYETNKKAMFEFYNLFLSVRRLDIPVICAANGHAIGAG
ECCCCEEECCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEECC
LSLTFACDIRVFANEAKYQFNFVKLGIHPGMGSSYTVKELFGTHVANRLLFLAETFNGEE
EEEEEEEEEEEEECCCEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCC
AFRLGLCNDSVPQKEVLGRATEIAIVLSESAPLALSELKKNTYDREKLETALRKEAESQA
EEEEECCCCCCCHHHHHCCCEEEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHH
RNFISADFKETIKAIEQKRKPIFKGL
HHHHHHHHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure
MEFIDQDTIDLGSGNKILKLSLNNPETRNSMTREMGLEFKKIIDGLMETTEKNKPRVVIL
CCCCCCCCEECCCCCEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEE
TGKNDIFSAGGNFELLKSLSNKDYETNKKAMFEFYNLFLSVRRLDIPVICAANGHAIGAG
ECCCCEEECCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEECC
LSLTFACDIRVFANEAKYQFNFVKLGIHPGMGSSYTVKELFGTHVANRLLFLAETFNGEE
EEEEEEEEEEEEECCCEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCC
AFRLGLCNDSVPQKEVLGRATEIAIVLSESAPLALSELKKNTYDREKLETALRKEAESQA
EEEEECCCCCCCHHHHHCCCEEEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHH
RNFISADFKETIKAIEQKRKPIFKGL
HHHHHHHHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]