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The map label for this gene is ribD [H]

Identifier: 116328771

GI number: 116328771

Start: 2518811

End: 2520109

Strand: Reverse

Name: ribD [H]

Synonym: LBL_2146

Alternate gene names: 116328771

Gene position: 2520109-2518811 (Counterclockwise)

Preceding gene: 116328772

Following gene: 116328770

Centisome position: 69.72

GC content: 43.49

Gene sequence:

>1299_bases
ATGACTCTGCTCCCGGAAGAATTTCGGGAGGAATTGCGTAAACTTTCCTTTTTATCGACGGGCGAAAGTTCTCCGAATCC
GCCCGTTTCTTGCCTTATCACGGACGTTGACAACGCGCGTATCCTTGCCAAAGGTTGGACTTCTCCGACCGGAGGGCCGC
ACGCGGAGAGGAATGCATATTACGAATTTGTAAAGAATGGGTTTTTCAAAGAACCGCATAACGTTTGGGTTACTCTTGAG
CCTTGTACTCATAGCGGAAAAACTCCTCCTTGTTTGGATCTGATTTTAGAACACAAACCAAAGACCCTTTATTATGGCCG
AAAGGATCCGAACCCGCTTGTTCGGGAGAACGAAGGATTGGAACTTTGTCGGCGGAGAGGAATTTTAGTTGTGGCCGAAC
CGGGTTTGAGGGAAATCGCGGAGGAAAGTTTGTTCGGATTCGTTTCTCGGATCGAAAGAAAAAAACCTTCTATGATTTTG
AAGACCGCACTTTCCAAAGAAGGTTTTTTTTCCAAAAGAGATAAGTTTCCGGTCCGTTTTTCAGGAAATATTTCTAATCA
CTTAACGTCGATTTTACGGGCAAAGTGCGACGCGGTCCTCGTGGGACCGGGAACCTTGTTCCACGATAATCCCGGTTTGG
AATTTCGGATCGGAGAAAATTGGCCGACCGATTTGAAGAAAATAAGGGAAAAAATTTTCGAAGAATATGACGGTTTAAAT
ATCGGTCGTAGGTTCGAAGCGGAATCTGGCTATAGAAACGCCGGGGCTCCCTACTTCCTGAAAAATGTCCTAAAATATGG
ATTTGAGCCGGAAATTTTGGAAATCCACCGGAAGTTCCGGAAGCGATATCAGCCATATCGTGTTTTTATTATATTCGAAG
AAAAGAATGTATCGGAAGGGTGGATTGAAAAACAAAAGGAGATCAACGAAAAAAACGGTTCTAAAAAATGTGTTTTTCTC
TTCAAAAGAGGTGCATTTTTTGAGGAAAGAACCGAAGAACGACTTCGATCCCTTACCGAAAAGGAAATTTATACTTTCGA
TCCGGAAACACTCGCGGAAGAATGTTTTGCATTTTTATCTTCGATCGGAGTGAATCTGTTGCTTGTGGAGGGGGGAAATC
TGATGTACGAAACTTTCTTTCCTAAAATGCGGGAGAACGATCTCATTCTGAAAATTCAATCTCCTCGTTCCGTTTCCAAT
GGGATAAAACCTTTGCTTATCACGAATGCAGAGACTTTATTTTGGAAAGTAAACGTGGGAGAGGATATCTGGGAGGCGCA
CGGATGTTTACGGGTTTAG

Upstream 100 bases:

>100_bases
TACTCACCTTCGGGATTATTATCGGAACGTATTCTTCCATTTTTATTGCGGCCCCTCTCGTGGATATCTACGACCATATT
ATACGAAAGGCTCGAGACTG

Downstream 100 bases:

>100_bases
TGGAAACCACTGGAAGGATTCTTGAAATTCAAGAAACGACCGAAGGAAGAGATTTTTTAGTGGAGACGAAGTGGACTCGG
CCGGATCTCAAATTAGGCGA

Product: pyrimidine deaminase, riboflavin biosynthesis

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MTLLPEEFREELRKLSFLSTGESSPNPPVSCLITDVDNARILAKGWTSPTGGPHAERNAYYEFVKNGFFKEPHNVWVTLE
PCTHSGKTPPCLDLILEHKPKTLYYGRKDPNPLVRENEGLELCRRRGILVVAEPGLREIAEESLFGFVSRIERKKPSMIL
KTALSKEGFFSKRDKFPVRFSGNISNHLTSILRAKCDAVLVGPGTLFHDNPGLEFRIGENWPTDLKKIREKIFEEYDGLN
IGRRFEAESGYRNAGAPYFLKNVLKYGFEPEILEIHRKFRKRYQPYRVFIIFEEKNVSEGWIEKQKEINEKNGSKKCVFL
FKRGAFFEERTEERLRSLTEKEIYTFDPETLAEECFAFLSSIGVNLLLVEGGNLMYETFFPKMRENDLILKIQSPRSVSN
GIKPLLITNAETLFWKVNVGEDIWEAHGCLRV

Sequences:

>Translated_432_residues
MTLLPEEFREELRKLSFLSTGESSPNPPVSCLITDVDNARILAKGWTSPTGGPHAERNAYYEFVKNGFFKEPHNVWVTLE
PCTHSGKTPPCLDLILEHKPKTLYYGRKDPNPLVRENEGLELCRRRGILVVAEPGLREIAEESLFGFVSRIERKKPSMIL
KTALSKEGFFSKRDKFPVRFSGNISNHLTSILRAKCDAVLVGPGTLFHDNPGLEFRIGENWPTDLKKIREKIFEEYDGLN
IGRRFEAESGYRNAGAPYFLKNVLKYGFEPEILEIHRKFRKRYQPYRVFIIFEEKNVSEGWIEKQKEINEKNGSKKCVFL
FKRGAFFEERTEERLRSLTEKEIYTFDPETLAEECFAFLSSIGVNLLLVEGGNLMYETFFPKMRENDLILKIQSPRSVSN
GIKPLLITNAETLFWKVNVGEDIWEAHGCLRV
>Mature_431_residues
TLLPEEFREELRKLSFLSTGESSPNPPVSCLITDVDNARILAKGWTSPTGGPHAERNAYYEFVKNGFFKEPHNVWVTLEP
CTHSGKTPPCLDLILEHKPKTLYYGRKDPNPLVRENEGLELCRRRGILVVAEPGLREIAEESLFGFVSRIERKKPSMILK
TALSKEGFFSKRDKFPVRFSGNISNHLTSILRAKCDAVLVGPGTLFHDNPGLEFRIGENWPTDLKKIREKIFEEYDGLNI
GRRFEAESGYRNAGAPYFLKNVLKYGFEPEILEIHRKFRKRYQPYRVFIIFEEKNVSEGWIEKQKEINEKNGSKKCVFLF
KRGAFFEERTEERLRSLTEKEIYTFDPETLAEECFAFLSSIGVNLLLVEGGNLMYETFFPKMRENDLILKIQSPRSVSNG
IKPLLITNAETLFWKVNVGEDIWEAHGCLRV

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=197, Percent_Identity=30.9644670050761, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 49831; Mature: 49700

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLPEEFREELRKLSFLSTGESSPNPPVSCLITDVDNARILAKGWTSPTGGPHAERNAY
CCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCHHHHH
YEFVKNGFFKEPHNVWVTLEPCTHSGKTPPCLDLILEHKPKTLYYGRKDPNPLVRENEGL
HHHHHCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCCCCCCH
ELCRRRGILVVAEPGLREIAEESLFGFVSRIERKKPSMILKTALSKEGFFSKRDKFPVRF
HHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCEEE
SGNISNHLTSILRAKCDAVLVGPGTLFHDNPGLEFRIGENWPTDLKKIREKIFEEYDGLN
CCCHHHHHHHHHHHCCCEEEECCCEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHCCCC
IGRRFEAESGYRNAGAPYFLKNVLKYGFEPEILEIHRKFRKRYQPYRVFIIFEEKNVSEG
CCCEECCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCHH
WIEKQKEINEKNGSKKCVFLFKRGAFFEERTEERLRSLTEKEIYTFDPETLAEECFAFLS
HHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCEEEECHHHHHHHHHHHHH
SIGVNLLLVEGGNLMYETFFPKMRENDLILKIQSPRSVSNGIKPLLITNAETLFWKVNVG
HCCCEEEEEECCCEEEEHHCCCCCCCCEEEEEECCCCHHCCCCEEEEECCCEEEEEEECC
EDIWEAHGCLRV
HHHHHHCCCCCC
>Mature Secondary Structure 
TLLPEEFREELRKLSFLSTGESSPNPPVSCLITDVDNARILAKGWTSPTGGPHAERNAY
CCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCHHHHH
YEFVKNGFFKEPHNVWVTLEPCTHSGKTPPCLDLILEHKPKTLYYGRKDPNPLVRENEGL
HHHHHCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCCCCCCH
ELCRRRGILVVAEPGLREIAEESLFGFVSRIERKKPSMILKTALSKEGFFSKRDKFPVRF
HHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCEEE
SGNISNHLTSILRAKCDAVLVGPGTLFHDNPGLEFRIGENWPTDLKKIREKIFEEYDGLN
CCCHHHHHHHHHHHCCCEEEECCCEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHCCCC
IGRRFEAESGYRNAGAPYFLKNVLKYGFEPEILEIHRKFRKRYQPYRVFIIFEEKNVSEG
CCCEECCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCHH
WIEKQKEINEKNGSKKCVFLFKRGAFFEERTEERLRSLTEKEIYTFDPETLAEECFAFLS
HHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCEEEECHHHHHHHHHHHHH
SIGVNLLLVEGGNLMYETFFPKMRENDLILKIQSPRSVSNGIKPLLITNAETLFWKVNVG
HCCCEEEEEECCCEEEEHHCCCCCCCCEEEEEECCCCHHCCCCEEEEECCCEEEEEEECC
EDIWEAHGCLRV
HHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9784136 [H]