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The map label for this gene is ribC [H]

Identifier: 116328770

GI number: 116328770

Start: 2518230

End: 2518826

Strand: Reverse

Name: ribC [H]

Synonym: LBL_2145

Alternate gene names: 116328770

Gene position: 2518826-2518230 (Counterclockwise)

Preceding gene: 116328771

Following gene: 116328769

Centisome position: 69.69

GC content: 42.04

Gene sequence:

>597_bases
ATGTTTACGGGTTTAGTGGAAACCACTGGAAGGATTCTTGAAATTCAAGAAACGACCGAAGGAAGAGATTTTTTAGTGGA
GACGAAGTGGACTCGGCCGGATCTCAAATTAGGCGATTCGATTGCGGTTAATGGTTGTTGTCAGACGGTTACCGAGTTTT
TTGAAGAAGGAAACCGTTTCAGATTCTACGCCAGTTTTAAAACGTTGGAACTTACGAATTTCAAATTTTTAAAAAAAGAT
GCAGAAGTCAATTTGGAACGAAGCGCCCTTCCGACAACCCGTTTGGGAGGACATCTCGTGAGCGGGCATGTAGATGGAAC
CGGAAAAGTTCTTAGCAAAGAAGAAAGAGAGGGAGGAAGTGTGGTTTGTTATACGGTCAGAAATGATTCTTCCCTTTCTA
AGTACATCGCTCCGAGAGGGAGTATTACCGTGGACGGGATTTCGTTGACTGTAGTAGATTCTCGTTCGAATGAATTCGAT
CTGATTTTGGTTCCGGAGACTCTTAAAAAAACAAATGCTAAGTCTTGGAGTTCCGACACAATTCTCAACTTAGAAATCGA
TCTTGTGGCGCGTTATTTAGAACAACTTCTGAAATAG

Upstream 100 bases:

>100_bases
CTCGTTCCGTTTCCAATGGGATAAAACCTTTGCTTATCACGAATGCAGAGACTTTATTTTGGAAAGTAAACGTGGGAGAG
GATATCTGGGAGGCGCACGG

Downstream 100 bases:

>100_bases
TTTTTGCTTTGAATATAATAAAGTTGTTGAAAGATTCCATAGTTCAGATTAACAAAACTGCTTCAATCGACCGTCTTCAT
GAAACAGAAATGAATGGAAA

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MFTGLVETTGRILEIQETTEGRDFLVETKWTRPDLKLGDSIAVNGCCQTVTEFFEEGNRFRFYASFKTLELTNFKFLKKD
AEVNLERSALPTTRLGGHLVSGHVDGTGKVLSKEEREGGSVVCYTVRNDSSLSKYIAPRGSITVDGISLTVVDSRSNEFD
LILVPETLKKTNAKSWSSDTILNLEIDLVARYLEQLLK

Sequences:

>Translated_198_residues
MFTGLVETTGRILEIQETTEGRDFLVETKWTRPDLKLGDSIAVNGCCQTVTEFFEEGNRFRFYASFKTLELTNFKFLKKD
AEVNLERSALPTTRLGGHLVSGHVDGTGKVLSKEEREGGSVVCYTVRNDSSLSKYIAPRGSITVDGISLTVVDSRSNEFD
LILVPETLKKTNAKSWSSDTILNLEIDLVARYLEQLLK
>Mature_198_residues
MFTGLVETTGRILEIQETTEGRDFLVETKWTRPDLKLGDSIAVNGCCQTVTEFFEEGNRFRFYASFKTLELTNFKFLKKD
AEVNLERSALPTTRLGGHLVSGHVDGTGKVLSKEEREGGSVVCYTVRNDSSLSKYIAPRGSITVDGISLTVVDSRSNEFD
LILVPETLKKTNAKSWSSDTILNLEIDLVARYLEQLLK

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=188, Percent_Identity=39.8936170212766, Blast_Score=112, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6319733, Length=208, Percent_Identity=31.7307692307692, Blast_Score=96, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 22135; Mature: 22135

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGLVETTGRILEIQETTEGRDFLVETKWTRPDLKLGDSIAVNGCCQTVTEFFEEGNRF
CCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCEEECHHHHHHHHHHHCCCEE
RFYASFKTLELTNFKFLKKDAEVNLERSALPTTRLGGHLVSGHVDGTGKVLSKEEREGGS
EEEEEEEEEEECCEEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCC
VVCYTVRNDSSLSKYIAPRGSITVDGISLTVVDSRSNEFDLILVPETLKKTNAKSWSSDT
EEEEEEECCCCHHHHHCCCCCEEECCEEEEEEECCCCCEEEEEECHHHHHCCCCCCCCCE
ILNLEIDLVARYLEQLLK
EEEEEHHHHHHHHHHHHC
>Mature Secondary Structure
MFTGLVETTGRILEIQETTEGRDFLVETKWTRPDLKLGDSIAVNGCCQTVTEFFEEGNRF
CCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCEEECHHHHHHHHHHHCCCEE
RFYASFKTLELTNFKFLKKDAEVNLERSALPTTRLGGHLVSGHVDGTGKVLSKEEREGGS
EEEEEEEEEEECCEEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCC
VVCYTVRNDSSLSKYIAPRGSITVDGISLTVVDSRSNEFDLILVPETLKKTNAKSWSSDT
EEEEEEECCCCHHHHHCCCCCEEECCEEEEEEECCCCCEEEEEECHHHHHCCCCCCCCCE
ILNLEIDLVARYLEQLLK
EEEEEHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8522537 [H]