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The map label for this gene is malL [H]

Identifier: 116328697

GI number: 116328697

Start: 2424760

End: 2426439

Strand: Reverse

Name: malL [H]

Synonym: LBL_2069

Alternate gene names: 116328697

Gene position: 2426439-2424760 (Counterclockwise)

Preceding gene: 116328702

Following gene: 116328696

Centisome position: 67.13

GC content: 40.48

Gene sequence:

>1680_bases
ATGACTGCGAAAAAAACAATTTCCAAAAAAAAATCCTCCTATTCAATCGATAAGTGGTGGCAAAAAACCACGATTTATCA
GATTTATCCTCGTTCTTTTGCAGATAGTAATCAAGACGGAATCGGAGACATTCCGGGCATCATTTCGAAGTTGGACTATT
TGCATGATCTCGGGTTTGAAACCATTTGGGTATCTCCTTTATATAAAAGTCCTCAGATGGATCACGGTTACGACGTTAGC
GACTATTATTCGATCGCTCCCGAATACGGAACCATTAAGGATGCAGAAAAACTAATAAAAGGAATTCATAAACGCGGAAT
GAAAATCGTTTTCGATATGGTAATGAATCACACCTCCATCGAACACGATTGGTTTCAACAATCCCGTTCTAACCGTGAAA
ACCCCAAAAGGGATTGGTATATTTGGAGAGACGGAAGAGGGAAGAATAAACCCCCTAATAATTGGAGCTCGTTCGTTACT
CCTAAAGCTTGGCATTACGATTCTAATACCGATCAATGGTATCTGGCGAGTTTTTTGGAATTTCAACCGGACTTGAATTA
TTACAATCCTGAAGTCAAAAAAGCGATGTTTGACGTTTTGCGTTTTTGGCTTCGGAAGGGAGTGGACGGCTTTCGTTTGG
ATATCTTTCATGCGATCTATAAAGATAAACACTTTCGAGATAATCCGTTTCGGTTTAAATATATCGTCTCGGAAAACGAT
CACGACGGCTATTTTCAAAGTAGGGTTTATACCGTAAATCATCCGAATAACTTCGTATTTGCAAAAGAACTAAGGGCTGT
TTTGGACGAGTTCGACGGGGATCGTTTTGCGGTCGGAGAGGTCGCAGGAGATGATCATATCATCAAACGTTACTTAGGCG
AAGAAAAAGACGGTCTGAATCTTATCTTTTTGTTTGAAACCCTACTGCTAAAATTCAAAACGAACTTTTTTAGGGGTATC
GTCAAGAAGATGGAGGAAGTGTATCCATATCCGAGTATTCCCACATATGTTTTTGGAAATCACGATCAAAGACGTTATAT
GATGAAGATCAACAACAATCTTGAAAAGGGAAAGTTGGTCGCCTTATTTCAATTTACCGCAAGAGGAGTTCCGGTCACTT
ATTACGGGGAAGAGATCGGTATGACCAACGAGACGATTAAATTGACGGAAGCTCAGGACCCCCTCGCGAGAATTTATCGT
TGGTTGGGAGATTCGTTTTCCGAGTTGTTGGGACTTGCGGACGTTATCATTCGGGATAGGGCGAGGTCTCCTATGCAGTG
GGACGATTCACCGAATGCCGGATTTACGAGTAGGGAGGCGACTCCTTGGATTCGAGTTCATGGGAATTATCGGGAAAGAA
ACGTTTTGATCGAATCGGAGGATAGGGATTCTCTTTTGAATACGTACAAAAATGTTCTTCATCTTAGAAACAAAAGTCGG
GCCCTAAAGGAAGGATCTTTGAGATTAATCGAAGAAAACGTTCCAAAAGATATGCTGGTCTATTTGAGAGAATTTGAAAA
AGAACGTAAACTGGTCGTTTTTAATTTCGGGAAAAAGGTCAGATTTTTTTCTAATCCGACCGATTGTGGAAAATATTTCT
TTTCCACTGTTCTTTTTGAGCACAACGAATTTGAACAATTCAAGATGCCGCCTTGCTCTGGAGTTATATTAGGGAATTGA

Upstream 100 bases:

>100_bases
TACAAATTCATATCTTCTGTTGAAACGAATTCAATTTGTAAGGAATACCGTCTTGACAACCTTCATTCTAATATTTTAGA
TTCCATAAAGCCGAAGCGAC

Downstream 100 bases:

>100_bases
TATATTTAAATAAATTAATTTTATATTTTATCGACCAAAAGGCATGATTGCTCATGGATGATCTGCCGGAGGCGTTTTTG
TTTCCGGGGTTTTTAAAGAC

Product: glycosidase

Products: NA

Alternate protein names: Dextrin 6-alpha-D-glucanohydrolase; Oligosaccharide alpha-1,6-glucosidase; Sucrase-isomaltase; Isomaltase [H]

Number of amino acids: Translated: 559; Mature: 558

Protein sequence:

>559_residues
MTAKKTISKKKSSYSIDKWWQKTTIYQIYPRSFADSNQDGIGDIPGIISKLDYLHDLGFETIWVSPLYKSPQMDHGYDVS
DYYSIAPEYGTIKDAEKLIKGIHKRGMKIVFDMVMNHTSIEHDWFQQSRSNRENPKRDWYIWRDGRGKNKPPNNWSSFVT
PKAWHYDSNTDQWYLASFLEFQPDLNYYNPEVKKAMFDVLRFWLRKGVDGFRLDIFHAIYKDKHFRDNPFRFKYIVSEND
HDGYFQSRVYTVNHPNNFVFAKELRAVLDEFDGDRFAVGEVAGDDHIIKRYLGEEKDGLNLIFLFETLLLKFKTNFFRGI
VKKMEEVYPYPSIPTYVFGNHDQRRYMMKINNNLEKGKLVALFQFTARGVPVTYYGEEIGMTNETIKLTEAQDPLARIYR
WLGDSFSELLGLADVIIRDRARSPMQWDDSPNAGFTSREATPWIRVHGNYRERNVLIESEDRDSLLNTYKNVLHLRNKSR
ALKEGSLRLIEENVPKDMLVYLREFEKERKLVVFNFGKKVRFFSNPTDCGKYFFSTVLFEHNEFEQFKMPPCSGVILGN

Sequences:

>Translated_559_residues
MTAKKTISKKKSSYSIDKWWQKTTIYQIYPRSFADSNQDGIGDIPGIISKLDYLHDLGFETIWVSPLYKSPQMDHGYDVS
DYYSIAPEYGTIKDAEKLIKGIHKRGMKIVFDMVMNHTSIEHDWFQQSRSNRENPKRDWYIWRDGRGKNKPPNNWSSFVT
PKAWHYDSNTDQWYLASFLEFQPDLNYYNPEVKKAMFDVLRFWLRKGVDGFRLDIFHAIYKDKHFRDNPFRFKYIVSEND
HDGYFQSRVYTVNHPNNFVFAKELRAVLDEFDGDRFAVGEVAGDDHIIKRYLGEEKDGLNLIFLFETLLLKFKTNFFRGI
VKKMEEVYPYPSIPTYVFGNHDQRRYMMKINNNLEKGKLVALFQFTARGVPVTYYGEEIGMTNETIKLTEAQDPLARIYR
WLGDSFSELLGLADVIIRDRARSPMQWDDSPNAGFTSREATPWIRVHGNYRERNVLIESEDRDSLLNTYKNVLHLRNKSR
ALKEGSLRLIEENVPKDMLVYLREFEKERKLVVFNFGKKVRFFSNPTDCGKYFFSTVLFEHNEFEQFKMPPCSGVILGN
>Mature_558_residues
TAKKTISKKKSSYSIDKWWQKTTIYQIYPRSFADSNQDGIGDIPGIISKLDYLHDLGFETIWVSPLYKSPQMDHGYDVSD
YYSIAPEYGTIKDAEKLIKGIHKRGMKIVFDMVMNHTSIEHDWFQQSRSNRENPKRDWYIWRDGRGKNKPPNNWSSFVTP
KAWHYDSNTDQWYLASFLEFQPDLNYYNPEVKKAMFDVLRFWLRKGVDGFRLDIFHAIYKDKHFRDNPFRFKYIVSENDH
DGYFQSRVYTVNHPNNFVFAKELRAVLDEFDGDRFAVGEVAGDDHIIKRYLGEEKDGLNLIFLFETLLLKFKTNFFRGIV
KKMEEVYPYPSIPTYVFGNHDQRRYMMKINNNLEKGKLVALFQFTARGVPVTYYGEEIGMTNETIKLTEAQDPLARIYRW
LGDSFSELLGLADVIIRDRARSPMQWDDSPNAGFTSREATPWIRVHGNYRERNVLIESEDRDSLLNTYKNVLHLRNKSRA
LKEGSLRLIEENVPKDMLVYLREFEKERKLVVFNFGKKVRFFSNPTDCGKYFFSTVLFEHNEFEQFKMPPCSGVILGN

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=528, Percent_Identity=33.9015151515151, Blast_Score=267, Evalue=2e-71,
Organism=Escherichia coli, GI1790687, Length=563, Percent_Identity=34.2806394316163, Blast_Score=298, Evalue=4e-82,
Organism=Escherichia coli, GI1786604, Length=499, Percent_Identity=22.0440881763527, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI87081873, Length=156, Percent_Identity=30.7692307692308, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI25147709, Length=493, Percent_Identity=25.1521298174442, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI32565753, Length=541, Percent_Identity=22.735674676525, Blast_Score=99, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6319776, Length=579, Percent_Identity=34.7150259067358, Blast_Score=293, Evalue=4e-80,
Organism=Saccharomyces cerevisiae, GI6322245, Length=558, Percent_Identity=34.0501792114695, Blast_Score=293, Evalue=4e-80,
Organism=Saccharomyces cerevisiae, GI6321731, Length=579, Percent_Identity=34.5423143350604, Blast_Score=293, Evalue=6e-80,
Organism=Saccharomyces cerevisiae, GI6321726, Length=551, Percent_Identity=34.3012704174229, Blast_Score=287, Evalue=3e-78,
Organism=Saccharomyces cerevisiae, GI6324416, Length=503, Percent_Identity=36.3817097415507, Blast_Score=286, Evalue=9e-78,
Organism=Saccharomyces cerevisiae, GI6322241, Length=503, Percent_Identity=36.3817097415507, Blast_Score=285, Evalue=1e-77,
Organism=Saccharomyces cerevisiae, GI6322021, Length=503, Percent_Identity=36.3817097415507, Blast_Score=285, Evalue=1e-77,
Organism=Drosophila melanogaster, GI24586599, Length=532, Percent_Identity=35.1503759398496, Blast_Score=298, Evalue=4e-81,
Organism=Drosophila melanogaster, GI221330053, Length=519, Percent_Identity=35.4527938342967, Blast_Score=295, Evalue=4e-80,
Organism=Drosophila melanogaster, GI24583745, Length=530, Percent_Identity=35.0943396226415, Blast_Score=292, Evalue=4e-79,
Organism=Drosophila melanogaster, GI24586593, Length=485, Percent_Identity=36.701030927835, Blast_Score=289, Evalue=5e-78,
Organism=Drosophila melanogaster, GI24583749, Length=521, Percent_Identity=36.468330134357, Blast_Score=285, Evalue=7e-77,
Organism=Drosophila melanogaster, GI24583747, Length=521, Percent_Identity=36.468330134357, Blast_Score=285, Evalue=7e-77,
Organism=Drosophila melanogaster, GI45549022, Length=536, Percent_Identity=34.1417910447761, Blast_Score=283, Evalue=2e-76,
Organism=Drosophila melanogaster, GI24586597, Length=498, Percent_Identity=35.140562248996, Blast_Score=281, Evalue=8e-76,
Organism=Drosophila melanogaster, GI24586591, Length=493, Percent_Identity=34.6855983772819, Blast_Score=273, Evalue=2e-73,
Organism=Drosophila melanogaster, GI24586589, Length=496, Percent_Identity=35.8870967741936, Blast_Score=270, Evalue=3e-72,
Organism=Drosophila melanogaster, GI24586587, Length=540, Percent_Identity=33.1481481481482, Blast_Score=265, Evalue=6e-71,
Organism=Drosophila melanogaster, GI281360393, Length=429, Percent_Identity=34.2657342657343, Blast_Score=218, Evalue=1e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.10 [H]

Molecular weight: Translated: 66006; Mature: 65874

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAKKTISKKKSSYSIDKWWQKTTIYQIYPRSFADSNQDGIGDIPGIISKLDYLHDLGFE
CCCHHHHHHHHCCCCHHHHHHHCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
TIWVSPLYKSPQMDHGYDVSDYYSIAPEYGTIKDAEKLIKGIHKRGMKIVFDMVMNHTSI
EEEECCCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCC
EHDWFQQSRSNRENPKRDWYIWRDGRGKNKPPNNWSSFVTPKAWHYDSNTDQWYLASFLE
CHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCHHCCCCCEEECCCCCCHHHHHHHHH
FQPDLNYYNPEVKKAMFDVLRFWLRKGVDGFRLDIFHAIYKDKHFRDNPFRFKYIVSEND
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEEECCC
HDGYFQSRVYTVNHPNNFVFAKELRAVLDEFDGDRFAVGEVAGDDHIIKRYLGEEKDGLN
CCCEEECEEEEEECCCCEEEHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCCCCCE
LIFLFETLLLKFKTNFFRGIVKKMEEVYPYPSIPTYVFGNHDQRRYMMKINNNLEKGKLV
EHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEEECCCCCCCCEE
ALFQFTARGVPVTYYGEEIGMTNETIKLTEAQDPLARIYRWLGDSFSELLGLADVIIRDR
EEEEECCCCCEEEEECHHHCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHC
ARSPMQWDDSPNAGFTSREATPWIRVHGNYRERNVLIESEDRDSLLNTYKNVLHLRNKSR
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
ALKEGSLRLIEENVPKDMLVYLREFEKERKLVVFNFGKKVRFFSNPTDCGKYFFSTVLFE
HHHCCCCEEEHHCCCHHHHHHHHHHHHCCCEEEEECCCEEEEECCCCHHHHHHHHHHHHC
HNEFEQFKMPPCSGVILGN
CCCHHHCCCCCCCCEEECC
>Mature Secondary Structure 
TAKKTISKKKSSYSIDKWWQKTTIYQIYPRSFADSNQDGIGDIPGIISKLDYLHDLGFE
CCHHHHHHHHCCCCHHHHHHHCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
TIWVSPLYKSPQMDHGYDVSDYYSIAPEYGTIKDAEKLIKGIHKRGMKIVFDMVMNHTSI
EEEECCCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCC
EHDWFQQSRSNRENPKRDWYIWRDGRGKNKPPNNWSSFVTPKAWHYDSNTDQWYLASFLE
CHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCHHCCCCCEEECCCCCCHHHHHHHHH
FQPDLNYYNPEVKKAMFDVLRFWLRKGVDGFRLDIFHAIYKDKHFRDNPFRFKYIVSEND
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEEECCC
HDGYFQSRVYTVNHPNNFVFAKELRAVLDEFDGDRFAVGEVAGDDHIIKRYLGEEKDGLN
CCCEEECEEEEEECCCCEEEHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCCCCCE
LIFLFETLLLKFKTNFFRGIVKKMEEVYPYPSIPTYVFGNHDQRRYMMKINNNLEKGKLV
EHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEEECCCCCCCCEE
ALFQFTARGVPVTYYGEEIGMTNETIKLTEAQDPLARIYRWLGDSFSELLGLADVIIRDR
EEEEECCCCCEEEEECHHHCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHC
ARSPMQWDDSPNAGFTSREATPWIRVHGNYRERNVLIESEDRDSLLNTYKNVLHLRNKSR
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
ALKEGSLRLIEENVPKDMLVYLREFEKERKLVVFNFGKKVRFFSNPTDCGKYFFSTVLFE
HHHCCCCEEEHHCCCHHHHHHHHHHHHCCCEEEEECCCEEEEECCCCHHHHHHHHHHHHC
HNEFEQFKMPPCSGVILGN
CCCHHHCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2120057; 8370659; 9193006 [H]