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The map label for this gene is ugd [H]

Identifier: 116328702

GI number: 116328702

Start: 2431252

End: 2432562

Strand: Reverse

Name: ugd [H]

Synonym: LBL_2074

Alternate gene names: 116328702

Gene position: 2432562-2431252 (Counterclockwise)

Preceding gene: 116328703

Following gene: 116328697

Centisome position: 67.3

GC content: 43.02

Gene sequence:

>1311_bases
ATGAAAGTTTGTGTGGTTGGAAGCGGATACGTAGGTCTTGTCGCAGGCGCTTGTTTTGCGGAATATGGAAATCATGTGAT
TTGTGTCGATAAAGACGAAGCAAAAATCGCAAATCTTAAAAAAGGTGTCATTCCCATTTATGAACCGGGACTTTCCGAAT
TGGTTTTAACTAACTGGAAGGAAAAAAGGCTCGAGTTCACCACTTCTCTGCATGAGGGAGTACAGAAATCGGATATCATT
TTTATCGCTGTGGGAACTCCCACCTTGCCGGATGGTTCTTCCGATCTTTCCGCGGTTTTTGCGGTGGCAAAAGAAATTGG
TAAGTCTATGAACGGATACAAAGTCATCGTAGACAAATCTACGGTACCGGTCGGAACCGCGGCCCAAGTGAAAGCGATTA
TTGCAAATGAAACCAAAGAAGAATTCGACGTTGTTTCTAATCCGGAATTTTTGAAAGAAGGCGCAGCGATCGACGATTTC
ATGCGCCCCGAAAGAGTCGTAATCGGTTCCGAGACCCAAAAAGCCGGGGATTTGATCGCACAACTTTATGCTCCTTTTGT
TCTGAACGGAAATCCTATCTTAAGAATGGGAGTCGTTTCCGCGGAACTCACGAAATACGCGTGTAACGCGTTTCTTGCTA
CTAAGATTTCTTTTGCCAACGAAATCGCAAATCTTTGCGAGACTGTCGGAGGAAATTACGAAGATGTTCGTAAAGGGATG
GGAACTGATTCTAGAATCGGGAGACAGTTTTTATACGCTGGAATCGGGTATGGTGGTTCTTGTTTTCCTAAGGATGTTCG
CGCTTTGATTAAAACTTCTGAAGACGAAGGTTCTCCTCTTCGGATCATCCGTAAAGTGGAAGAGGTCAACGAAACTCAGA
AACTCAGACTTTATGAAAAAATTGTGAAGTTCTACGGAGAATCGAACCTTGCCGGAATGACCTTCGCAGTTTGGGGACTT
TCTTTCAAACCCGGCACCGACGATATGAGAGAAGCTCCTTCAATTCCCTTACTTCTGAAATTATATGATAAAAACGTAAA
ATTATGCGTCTACGATCCGGTCTCGAAAGAAACCTCGAAAGTTTATTTTGAAGGGAAAGTGGAATATGCGACTGACGCAT
ATTCCGCTTTGAATGGTGCGGATGCCTTGTTACTCCTAACCGAATGGAGAGAATTCAGAGAGCCTGATTTTTCAAAAATT
AAGAACCTTTTGAAGAATCAGGTCATCTTCGACGGAAGGAACCAATATTCCCCCGAATTGATGAAAACGAAAGGATTTCA
ATATTTCTCTATCGGTAAGCCGAACGTATAA

Upstream 100 bases:

>100_bases
GATTGCTTGGCTTCCGGTACAAGGTAGTCTTAAAAAAGACACTTCTTCCTGATTTATTTTTCTTTCTCAACCTGAAAAGG
TCGGAATTCTGGTTCTCAAT

Downstream 100 bases:

>100_bases
TCTTTTTAACAGGAAGTCCGTCTCAAAATTCGAAGAGAAATCATGATCATGATTTTTAAGCCGCCGGTAACGGAGCGCAA
TAGTTCTCACAGATTGCCTC

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MKVCVVGSGYVGLVAGACFAEYGNHVICVDKDEAKIANLKKGVIPIYEPGLSELVLTNWKEKRLEFTTSLHEGVQKSDII
FIAVGTPTLPDGSSDLSAVFAVAKEIGKSMNGYKVIVDKSTVPVGTAAQVKAIIANETKEEFDVVSNPEFLKEGAAIDDF
MRPERVVIGSETQKAGDLIAQLYAPFVLNGNPILRMGVVSAELTKYACNAFLATKISFANEIANLCETVGGNYEDVRKGM
GTDSRIGRQFLYAGIGYGGSCFPKDVRALIKTSEDEGSPLRIIRKVEEVNETQKLRLYEKIVKFYGESNLAGMTFAVWGL
SFKPGTDDMREAPSIPLLLKLYDKNVKLCVYDPVSKETSKVYFEGKVEYATDAYSALNGADALLLLTEWREFREPDFSKI
KNLLKNQVIFDGRNQYSPELMKTKGFQYFSIGKPNV

Sequences:

>Translated_436_residues
MKVCVVGSGYVGLVAGACFAEYGNHVICVDKDEAKIANLKKGVIPIYEPGLSELVLTNWKEKRLEFTTSLHEGVQKSDII
FIAVGTPTLPDGSSDLSAVFAVAKEIGKSMNGYKVIVDKSTVPVGTAAQVKAIIANETKEEFDVVSNPEFLKEGAAIDDF
MRPERVVIGSETQKAGDLIAQLYAPFVLNGNPILRMGVVSAELTKYACNAFLATKISFANEIANLCETVGGNYEDVRKGM
GTDSRIGRQFLYAGIGYGGSCFPKDVRALIKTSEDEGSPLRIIRKVEEVNETQKLRLYEKIVKFYGESNLAGMTFAVWGL
SFKPGTDDMREAPSIPLLLKLYDKNVKLCVYDPVSKETSKVYFEGKVEYATDAYSALNGADALLLLTEWREFREPDFSKI
KNLLKNQVIFDGRNQYSPELMKTKGFQYFSIGKPNV
>Mature_436_residues
MKVCVVGSGYVGLVAGACFAEYGNHVICVDKDEAKIANLKKGVIPIYEPGLSELVLTNWKEKRLEFTTSLHEGVQKSDII
FIAVGTPTLPDGSSDLSAVFAVAKEIGKSMNGYKVIVDKSTVPVGTAAQVKAIIANETKEEFDVVSNPEFLKEGAAIDDF
MRPERVVIGSETQKAGDLIAQLYAPFVLNGNPILRMGVVSAELTKYACNAFLATKISFANEIANLCETVGGNYEDVRKGM
GTDSRIGRQFLYAGIGYGGSCFPKDVRALIKTSEDEGSPLRIIRKVEEVNETQKLRLYEKIVKFYGESNLAGMTFAVWGL
SFKPGTDDMREAPSIPLLLKLYDKNVKLCVYDPVSKETSKVYFEGKVEYATDAYSALNGADALLLLTEWREFREPDFSKI
KNLLKNQVIFDGRNQYSPELMKTKGFQYFSIGKPNV

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=462, Percent_Identity=37.012987012987, Blast_Score=262, Evalue=4e-70,
Organism=Homo sapiens, GI296040438, Length=364, Percent_Identity=37.6373626373626, Blast_Score=209, Evalue=3e-54,
Organism=Homo sapiens, GI296040443, Length=311, Percent_Identity=37.9421221864952, Blast_Score=178, Evalue=8e-45,
Organism=Escherichia coli, GI1788340, Length=372, Percent_Identity=28.494623655914, Blast_Score=158, Evalue=5e-40,
Organism=Escherichia coli, GI48994968, Length=410, Percent_Identity=26.5853658536585, Blast_Score=118, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI17560350, Length=460, Percent_Identity=36.304347826087, Blast_Score=259, Evalue=1e-69,
Organism=Drosophila melanogaster, GI17136908, Length=464, Percent_Identity=35.5603448275862, Blast_Score=261, Evalue=8e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 47993; Mature: 47993

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVCVVGSGYVGLVAGACFAEYGNHVICVDKDEAKIANLKKGVIPIYEPGLSELVLTNWK
CEEEEECCCHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHCCCCCCCCCCHHHHHHCCCH
EKRLEFTTSLHEGVQKSDIIFIAVGTPTLPDGSSDLSAVFAVAKEIGKSMNGYKVIVDKS
HHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECC
TVPVGTAAQVKAIIANETKEEFDVVSNPEFLKEGAAIDDFMRPERVVIGSETQKAGDLIA
CCCCCCHHHHHHHHHCCCHHHHCCCCCHHHHHCCCCHHHHCCCCEEEECCCCHHHHHHHH
QLYAPFVLNGNPILRMGVVSAELTKYACNAFLATKISFANEIANLCETVGGNYEDVRKGM
HHHCCEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCC
GTDSRIGRQFLYAGIGYGGSCFPKDVRALIKTSEDEGSPLRIIRKVEEVNETQKLRLYEK
CCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCHHHHHHHHHH
IVKFYGESNLAGMTFAVWGLSFKPGTDDMREAPSIPLLLKLYDKNVKLCVYDPVSKETSK
HHHHHCCCCCCCEEEEEEECCCCCCCCHHHHCCCCCEEEEEECCCCEEEEECCCCCCCCE
VYFEGKVEYATDAYSALNGADALLLLTEWREFREPDFSKIKNLLKNQVIFDGRNQYSPEL
EEEEEEEEEHHHHHHHCCCCCEEEEHHHHHHHCCCCHHHHHHHHHCCEEECCCCCCCCHH
MKTKGFQYFSIGKPNV
HHHCCCEEEECCCCCC
>Mature Secondary Structure
MKVCVVGSGYVGLVAGACFAEYGNHVICVDKDEAKIANLKKGVIPIYEPGLSELVLTNWK
CEEEEECCCHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHCCCCCCCCCCHHHHHHCCCH
EKRLEFTTSLHEGVQKSDIIFIAVGTPTLPDGSSDLSAVFAVAKEIGKSMNGYKVIVDKS
HHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECC
TVPVGTAAQVKAIIANETKEEFDVVSNPEFLKEGAAIDDFMRPERVVIGSETQKAGDLIA
CCCCCCHHHHHHHHHCCCHHHHCCCCCHHHHHCCCCHHHHCCCCEEEECCCCHHHHHHHH
QLYAPFVLNGNPILRMGVVSAELTKYACNAFLATKISFANEIANLCETVGGNYEDVRKGM
HHHCCEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCC
GTDSRIGRQFLYAGIGYGGSCFPKDVRALIKTSEDEGSPLRIIRKVEEVNETQKLRLYEK
CCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCHHHHHHHHHH
IVKFYGESNLAGMTFAVWGLSFKPGTDDMREAPSIPLLLKLYDKNVKLCVYDPVSKETSK
HHHHHCCCCCCCEEEEEEECCCCCCCCHHHHCCCCCEEEEEECCCCEEEEECCCCCCCCE
VYFEGKVEYATDAYSALNGADALLLLTEWREFREPDFSKIKNLLKNQVIFDGRNQYSPEL
EEEEEEEEEHHHHHHHCCCCCEEEEHHHHHHHCCCCHHHHHHHHHCCEEECCCCCCCCHH
MKTKGFQYFSIGKPNV
HHHCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]