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The map label for this gene is atoS [C]

Identifier: 116328666

GI number: 116328666

Start: 2374597

End: 2376126

Strand: Reverse

Name: atoS [C]

Synonym: LBL_2033

Alternate gene names: 116328666

Gene position: 2376126-2374597 (Counterclockwise)

Preceding gene: 116328667

Following gene: 116328665

Centisome position: 65.74

GC content: 38.89

Gene sequence:

>1530_bases
TTGTTTAGTAACGATTCATCGGACGAGGTTTCTGTTTGTTTAATCGAAGACGACGAGGACGATTCGATTCTTTTTAGGGA
ATATTCGGACGAGATTCCGTATCCCAAATACAATATCACTCGCTTTAAGGATGCCCCGAGCGTGCTTGCGGATTTGAAAG
TTAATCCTTCCGGGTATAAGATCTATGTGGTGGATCATTTTTTAGGATCGCAAACCGGATTAGAAATTTTGCACGAGATT
CGTACCGTTGTTGGTTCCGTTTTTGCTGTTTTGATTTCGGGGATTTCGAAAGAGGAAATAGAAATCATCGTAAAAGAAGA
GGGATTTCAAGGTTATCTTGAGAAGAAGAATCTTTCCACATTTCATATTGCAAAAACCTTTTTTACGGTTTTGAAGGAGA
AAGGGAATTCCGAGGCGGGCCATACTTTCATGGATACTTTTCTTATAAAAATGGAAACCATATCTCAATTTTCCGGAGGG
ATTGCTCACGATTTTAATAATATTCTGAACGTCATCGTAGCCAACTTGGATATGCTGGAGATGCAGTGTAAGAATCAGCC
GGATGTTTTGAATCGAATTCGTTCCGCACAAAATGCTGTTATGCGAGGCGCGGAAGTAAATAAGAAATTATTGAATTTTT
CTAGAAAACAATCTTTATATCCGGAAGTAGTGGATCCGAACGCGTTGATCGCCGATTATTTGGGAAAAGCACAGGATGTT
TTTCCGCAGAACGTTCAAGTGAACTTTGATCCTCGTTCGGAGGGAGATCTCTGTCGGATCGATCGAAGCGAATTTGCAAA
TTGTCTTATGCATTTGCTCCAAAATGCGAAGGAGGCCTTCGAAGAATCCGAAGGAAGTATTTTAATAGAAACTGATACGA
TCGTTCTGAATTCTAAGGATAAATCACTCGGGTTAAAGGAAGGACATTATCTTTTACTTAGGATTGCGGACAATGGTAAG
GGCGTGGATTCGAACATAGCCGATAAAATTTTCGAACCTTTTTTCACTACAAAACCGAAAGGGAAACATTCGGGACTTGG
TCTTTCCATGGTCTTCGGTTTTGTGCAAAGAAGCGGAGGGCGAATCGTATTTGAATCCTATTCGAATATCGGTTCCGATT
TTTATATCTATCTTCCTATTGAGGACATAAAATCAAATTCACATTTCGTAAAACCGGAATCCTCAAAAAAACCAAAGGAA
ATTTTTTATTTTTCAAATGAAGGAGAATTTTCAAAGAGAACGTCTTATATTCTTCAGAAATCGGGGTATAGGCTACGTCA
TTTTAGGGATCTAAACGTTTTTGAATCTTATCTTTCTAATATAAATTCCGAAACTATTTTACTTTCGGAAACTTGGCTGG
AAGATTTTTCGAAGTGGAAGGAGATTGCGGTGAGGGCGCAAAACTCGGATTTGAAAGTGAAAATCTTTTATTTTTCCTCA
TCGGTCGACGCAAACGATTCGGAAAGTTCAGCGGGGATCTCTTGGCCCGTATCTAGAAAGTCTCTTGAAAGTCGTTTTAA
TATATTTTAA

Upstream 100 bases:

>100_bases
GGTGCAAGTTCTTTCATTCGAAAACCCGTGGAGTTTGATGCGTTTATGGAAACGATCCGAGCTCTGGGAGAATATTGGTT
TGAGATCGTGGAGCTTCCCA

Downstream 100 bases:

>100_bases
TTGAATACTCATGAATCAGCCTAAATTACCCAATCTACTGATTCTAGACGATGAGGAAGAAATTGCAGGTATCCTCGGGG
ATATAGCTAAACAATGTGGT

Product: sensor histidine kinase and response regulator of a two component complex

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MFSNDSSDEVSVCLIEDDEDDSILFREYSDEIPYPKYNITRFKDAPSVLADLKVNPSGYKIYVVDHFLGSQTGLEILHEI
RTVVGSVFAVLISGISKEEIEIIVKEEGFQGYLEKKNLSTFHIAKTFFTVLKEKGNSEAGHTFMDTFLIKMETISQFSGG
IAHDFNNILNVIVANLDMLEMQCKNQPDVLNRIRSAQNAVMRGAEVNKKLLNFSRKQSLYPEVVDPNALIADYLGKAQDV
FPQNVQVNFDPRSEGDLCRIDRSEFANCLMHLLQNAKEAFEESEGSILIETDTIVLNSKDKSLGLKEGHYLLLRIADNGK
GVDSNIADKIFEPFFTTKPKGKHSGLGLSMVFGFVQRSGGRIVFESYSNIGSDFYIYLPIEDIKSNSHFVKPESSKKPKE
IFYFSNEGEFSKRTSYILQKSGYRLRHFRDLNVFESYLSNINSETILLSETWLEDFSKWKEIAVRAQNSDLKVKIFYFSS
SVDANDSESSAGISWPVSRKSLESRFNIF

Sequences:

>Translated_509_residues
MFSNDSSDEVSVCLIEDDEDDSILFREYSDEIPYPKYNITRFKDAPSVLADLKVNPSGYKIYVVDHFLGSQTGLEILHEI
RTVVGSVFAVLISGISKEEIEIIVKEEGFQGYLEKKNLSTFHIAKTFFTVLKEKGNSEAGHTFMDTFLIKMETISQFSGG
IAHDFNNILNVIVANLDMLEMQCKNQPDVLNRIRSAQNAVMRGAEVNKKLLNFSRKQSLYPEVVDPNALIADYLGKAQDV
FPQNVQVNFDPRSEGDLCRIDRSEFANCLMHLLQNAKEAFEESEGSILIETDTIVLNSKDKSLGLKEGHYLLLRIADNGK
GVDSNIADKIFEPFFTTKPKGKHSGLGLSMVFGFVQRSGGRIVFESYSNIGSDFYIYLPIEDIKSNSHFVKPESSKKPKE
IFYFSNEGEFSKRTSYILQKSGYRLRHFRDLNVFESYLSNINSETILLSETWLEDFSKWKEIAVRAQNSDLKVKIFYFSS
SVDANDSESSAGISWPVSRKSLESRFNIF
>Mature_509_residues
MFSNDSSDEVSVCLIEDDEDDSILFREYSDEIPYPKYNITRFKDAPSVLADLKVNPSGYKIYVVDHFLGSQTGLEILHEI
RTVVGSVFAVLISGISKEEIEIIVKEEGFQGYLEKKNLSTFHIAKTFFTVLKEKGNSEAGHTFMDTFLIKMETISQFSGG
IAHDFNNILNVIVANLDMLEMQCKNQPDVLNRIRSAQNAVMRGAEVNKKLLNFSRKQSLYPEVVDPNALIADYLGKAQDV
FPQNVQVNFDPRSEGDLCRIDRSEFANCLMHLLQNAKEAFEESEGSILIETDTIVLNSKDKSLGLKEGHYLLLRIADNGK
GVDSNIADKIFEPFFTTKPKGKHSGLGLSMVFGFVQRSGGRIVFESYSNIGSDFYIYLPIEDIKSNSHFVKPESSKKPKE
IFYFSNEGEFSKRTSYILQKSGYRLRHFRDLNVFESYLSNINSETILLSETWLEDFSKWKEIAVRAQNSDLKVKIFYFSS
SVDANDSESSAGISWPVSRKSLESRFNIF

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=239, Percent_Identity=28.8702928870293, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1790436, Length=245, Percent_Identity=25.7142857142857, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1786837, Length=136, Percent_Identity=33.8235294117647, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 57731; Mature: 57731

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSNDSSDEVSVCLIEDDEDDSILFREYSDEIPYPKYNITRFKDAPSVLADLKVNPSGYK
CCCCCCCCCEEEEEEECCCCCCEEEEECCCCCCCCCCCCEEECCCCHHHHEEEECCCCEE
IYVVDHFLGSQTGLEILHEIRTVVGSVFAVLISGISKEEIEIIVKEEGFQGYLEKKNLST
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHCCCCCH
FHIAKTFFTVLKEKGNSEAGHTFMDTFLIKMETISQFSGGIAHDFNNILNVIVANLDMLE
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHH
MQCKNQPDVLNRIRSAQNAVMRGAEVNKKLLNFSRKQSLYPEVVDPNALIADYLGKAQDV
HHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCHHHC
FPQNVQVNFDPRSEGDLCRIDRSEFANCLMHLLQNAKEAFEESEGSILIETDTIVLNSKD
CCCCCEEEECCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCC
KSLGLKEGHYLLLRIADNGKGVDSNIADKIFEPFFTTKPKGKHSGLGLSMVFGFVQRSGG
CCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCC
RIVFESYSNIGSDFYIYLPIEDIKSNSHFVKPESSKKPKEIFYFSNEGEFSKRTSYILQK
EEEEEECCCCCCCEEEEEEHHHCCCCCCEECCCCCCCCCEEEEECCCCCCHHHHHHHHHC
SGYRLRHFRDLNVFESYLSNINSETILLSETWLEDFSKWKEIAVRAQNSDLKVKIFYFSS
CCCEEEEEECHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHEEEECCCCEEEEEEEEEC
SVDANDSESSAGISWPVSRKSLESRFNIF
CCCCCCCCCCCCCCCCCCHHHHHHHCCCC
>Mature Secondary Structure
MFSNDSSDEVSVCLIEDDEDDSILFREYSDEIPYPKYNITRFKDAPSVLADLKVNPSGYK
CCCCCCCCCEEEEEEECCCCCCEEEEECCCCCCCCCCCCEEECCCCHHHHEEEECCCCEE
IYVVDHFLGSQTGLEILHEIRTVVGSVFAVLISGISKEEIEIIVKEEGFQGYLEKKNLST
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHCCCCCH
FHIAKTFFTVLKEKGNSEAGHTFMDTFLIKMETISQFSGGIAHDFNNILNVIVANLDMLE
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHH
MQCKNQPDVLNRIRSAQNAVMRGAEVNKKLLNFSRKQSLYPEVVDPNALIADYLGKAQDV
HHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCHHHC
FPQNVQVNFDPRSEGDLCRIDRSEFANCLMHLLQNAKEAFEESEGSILIETDTIVLNSKD
CCCCCEEEECCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCC
KSLGLKEGHYLLLRIADNGKGVDSNIADKIFEPFFTTKPKGKHSGLGLSMVFGFVQRSGG
CCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCC
RIVFESYSNIGSDFYIYLPIEDIKSNSHFVKPESSKKPKEIFYFSNEGEFSKRTSYILQK
EEEEEECCCCCCCEEEEEEHHHCCCCCCEECCCCCCCCCEEEEECCCCCCHHHHHHHHHC
SGYRLRHFRDLNVFESYLSNINSETILLSETWLEDFSKWKEIAVRAQNSDLKVKIFYFSS
CCCEEEEEECHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHEEEECCCCEEEEEEEEEC
SVDANDSESSAGISWPVSRKSLESRFNIF
CCCCCCCCCCCCCCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA