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The map label for this gene is rsbU [H]

Identifier: 116328546

GI number: 116328546

Start: 2214093

End: 2215346

Strand: Direct

Name: rsbU [H]

Synonym: LBL_1900

Alternate gene names: 116328546

Gene position: 2214093-2215346 (Clockwise)

Preceding gene: 116328545

Following gene: 116328547

Centisome position: 61.26

GC content: 41.63

Gene sequence:

>1254_bases
ATGGACGGCTCCCGACAATCAGAACAGAAAGGCCACGGCGATCCCCGTTATTCCATATTGTTTGAGATCGACTCGATCAT
TTTCTTGGACGGCAATTTCAGAGTGATCTTGGCTAATTCGGCCACAGAAAAAACATTCGGATATCTTTCTTCCGAGCTTA
TCGGCAATTCCATCGAACATTTGTTTTCACTTCGAATTCGAAAACGATTTTATAGAATTCTAAAAAACATAGCTGAACTT
CCGGATAAAAGAAGTCAAAAACCTTTCGGGCCGATTCGTATGATTCGAAAGGATAAAACGGTTTTGATTTCGGAGATTTC
CGTTTCGGTTACCGGACCTGAGGAAGATTACCAGTATCACGTCATCATTCGGAACATATCAGAAAAACATAGAATTCTAA
TGGATTTGAAACGAGCTAACGAGAGCTTGAGGAAAATGGATCGTGAAAAAGAAGAACTCTTGGAAAAACTCGAAGAGAAG
GTTCGACAGAGATCCAGGTTACTCGCTGGCTATTACAAAGGAATGAAAGAGGAATTGAATCTTGCGAAAAAGCTTCAGAC
GGAAATTCTTTCGGATATTCCTTCCGTTGCGGGGATTCAAATTCATTCCATGTATCTTCCGATGATGGAAGTGGGCGGGG
ATCTTTACGATTTATTTCAAATTCGTCCGGGGGCCCTCCGGGTTTTTCTTGCGGATGCGACGGGACACGGGATACAGGCC
GCTCTTCTTACGATGACTCTCAAAGGAATTTTGGAATCCATCAAAAAAAAGGATACCGATCCGGGAACTATTCTCACGGA
ATTCAACCACGAATATTGCAGGAATTTCGGAAATATAGGAATGTTCTTCTCTTGTTTTCTTGCGGATATAGATACTGTTT
CCAAAAAAATCTCGTATGCTTCCGGTGGCCATTCTACTCAATTCTTTCTTTCCAAAGATCTTGTGTTGGGGTTGGATCGA
ACCGGGTCTTTACTCGGTCTTGATTCGAACAATCGGTACGGTGTTTTTAAATTTAGTTATCAATACGGAGATCGTTTGTT
CTTATTCACGGATGGAATTTATGAGGAGTTTAATTCCGACAAGCAGCAGTTTGGGGAGCTCGCCGTTCAAAATATTCTCG
CGAAAAAATTTTCAGAGCCTATGGAAGAAACGATTCCGGCCATTTTACAAAGTCTGATCGAACATTTAGGATCACAGAAA
ATACAAGATGATATTACGGCCATCCTGTTGGCCTTGAATTTCCCCGATCTTTGA

Upstream 100 bases:

>100_bases
ACGGAATCACACGTTTTTATTTGGATCTTCCCGAATCGCTTTGAAAGAAAGATTCTTAACTTTATGGGAGACGGTCTACT
AGATTCTTCTTCAATTTGCC

Downstream 100 bases:

>100_bases
AGTTTCCTTTTATATTGTCTCCTTTTTGGAAATTGGACTTTCCGGCCCGAATCATTAAGAATTTGTCGAGCTCTAATAGA
AGCGATGCGGCCTTAAGCTT

Product: Serine phosphatase sigma subunit regulator

Products: NA

Alternate protein names: Sigma factor sigB regulation protein rsbU [H]

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MDGSRQSEQKGHGDPRYSILFEIDSIIFLDGNFRVILANSATEKTFGYLSSELIGNSIEHLFSLRIRKRFYRILKNIAEL
PDKRSQKPFGPIRMIRKDKTVLISEISVSVTGPEEDYQYHVIIRNISEKHRILMDLKRANESLRKMDREKEELLEKLEEK
VRQRSRLLAGYYKGMKEELNLAKKLQTEILSDIPSVAGIQIHSMYLPMMEVGGDLYDLFQIRPGALRVFLADATGHGIQA
ALLTMTLKGILESIKKKDTDPGTILTEFNHEYCRNFGNIGMFFSCFLADIDTVSKKISYASGGHSTQFFLSKDLVLGLDR
TGSLLGLDSNNRYGVFKFSYQYGDRLFLFTDGIYEEFNSDKQQFGELAVQNILAKKFSEPMEETIPAILQSLIEHLGSQK
IQDDITAILLALNFPDL

Sequences:

>Translated_417_residues
MDGSRQSEQKGHGDPRYSILFEIDSIIFLDGNFRVILANSATEKTFGYLSSELIGNSIEHLFSLRIRKRFYRILKNIAEL
PDKRSQKPFGPIRMIRKDKTVLISEISVSVTGPEEDYQYHVIIRNISEKHRILMDLKRANESLRKMDREKEELLEKLEEK
VRQRSRLLAGYYKGMKEELNLAKKLQTEILSDIPSVAGIQIHSMYLPMMEVGGDLYDLFQIRPGALRVFLADATGHGIQA
ALLTMTLKGILESIKKKDTDPGTILTEFNHEYCRNFGNIGMFFSCFLADIDTVSKKISYASGGHSTQFFLSKDLVLGLDR
TGSLLGLDSNNRYGVFKFSYQYGDRLFLFTDGIYEEFNSDKQQFGELAVQNILAKKFSEPMEETIPAILQSLIEHLGSQK
IQDDITAILLALNFPDL
>Mature_417_residues
MDGSRQSEQKGHGDPRYSILFEIDSIIFLDGNFRVILANSATEKTFGYLSSELIGNSIEHLFSLRIRKRFYRILKNIAEL
PDKRSQKPFGPIRMIRKDKTVLISEISVSVTGPEEDYQYHVIIRNISEKHRILMDLKRANESLRKMDREKEELLEKLEEK
VRQRSRLLAGYYKGMKEELNLAKKLQTEILSDIPSVAGIQIHSMYLPMMEVGGDLYDLFQIRPGALRVFLADATGHGIQA
ALLTMTLKGILESIKKKDTDPGTILTEFNHEYCRNFGNIGMFFSCFLADIDTVSKKISYASGGHSTQFFLSKDLVLGLDR
TGSLLGLDSNNRYGVFKFSYQYGDRLFLFTDGIYEEFNSDKQQFGELAVQNILAKKFSEPMEETIPAILQSLIEHLGSQK
IQDDITAILLALNFPDL

Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to environmental stress conveyed from the rsbXST module [H]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017944
- InterPro:   IPR001932
- InterPro:   IPR014787
- InterPro:   IPR010822
- ProDom:   PD685490 [H]

Pfam domain/function: PF08673 RsbU_N; PF07228 SpoIIE [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 47540; Mature: 47540

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS50112 PAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGSRQSEQKGHGDPRYSILFEIDSIIFLDGNFRVILANSATEKTFGYLSSELIGNSIEH
CCCCCCCHHCCCCCCCEEEEEEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHH
LFSLRIRKRFYRILKNIAELPDKRSQKPFGPIRMIRKDKTVLISEISVSVTGPEEDYQYH
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCEEEEEEEEEEEECCCCCCEEE
VIIRNISEKHRILMDLKRANESLRKMDREKEELLEKLEEKVRQRSRLLAGYYKGMKEELN
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAKKLQTEILSDIPSVAGIQIHSMYLPMMEVGGDLYDLFQIRPGALRVFLADATGHGIQA
HHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHCCCHHHHHHCCCCEEEEEEECCCCCCHHH
ALLTMTLKGILESIKKKDTDPGTILTEFNHEYCRNFGNIGMFFSCFLADIDTVSKKISYA
HHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHC
SGGHSTQFFLSKDLVLGLDRTGSLLGLDSNNRYGVFKFSYQYGDRLFLFTDGIYEEFNSD
CCCCCEEEEEECCCEEECCCCCCEEEECCCCCEEEEEEEEECCCEEEEEECHHHHHHCCH
KQQFGELAVQNILAKKFSEPMEETIPAILQSLIEHLGSQKIQDDITAILLALNFPDL
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDGSRQSEQKGHGDPRYSILFEIDSIIFLDGNFRVILANSATEKTFGYLSSELIGNSIEH
CCCCCCCHHCCCCCCCEEEEEEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHH
LFSLRIRKRFYRILKNIAELPDKRSQKPFGPIRMIRKDKTVLISEISVSVTGPEEDYQYH
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCEEEEEEEEEEEECCCCCCEEE
VIIRNISEKHRILMDLKRANESLRKMDREKEELLEKLEEKVRQRSRLLAGYYKGMKEELN
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAKKLQTEILSDIPSVAGIQIHSMYLPMMEVGGDLYDLFQIRPGALRVFLADATGHGIQA
HHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHCCCHHHHHHCCCCEEEEEEECCCCCCHHH
ALLTMTLKGILESIKKKDTDPGTILTEFNHEYCRNFGNIGMFFSCFLADIDTVSKKISYA
HHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHC
SGGHSTQFFLSKDLVLGLDRTGSLLGLDSNNRYGVFKFSYQYGDRLFLFTDGIYEEFNSD
CCCCCEEEEEECCCEEECCCCCCEEEECCCCCEEEEEEEEECCCEEEEEECHHHHHHCCH
KQQFGELAVQNILAKKFSEPMEETIPAILQSLIEHLGSQKIQDDITAILLALNFPDL
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8002610; 8002609; 9384377; 8824586; 9786195; 12499568 [H]