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The map label for this gene is asnC

Identifier: 116328519

GI number: 116328519

Start: 2178097

End: 2179404

Strand: Reverse

Name: asnC

Synonym: LBL_1869

Alternate gene names: 116328519

Gene position: 2179404-2178097 (Counterclockwise)

Preceding gene: 116328526

Following gene: 116328518

Centisome position: 60.3

GC content: 42.43

Gene sequence:

>1308_bases
ATGTCTGAAATACCGATCGTTAGTAATCATGATTTGGAAAAATACGTGGATCGTAAAGTTGTCATCCAAGGTTGGGTACA
CGGAATCAGAGGAAGCAATGCAAGGCAGTTCATCTCGCTAAGAAACGGTGGAAGAATTTTACAAGTTCTCGCGGAAAAGG
AAATATTAGGCGAAGAAGTTTTTCAAACCGTAAAACATCTCCGTCAAGAAACTTCCGTATCTGTGGCGGGAACTTTGGTG
AAAAACGAAAAATCATCGGTTGGGTTCGAACTTATAATGGATCGGATTCGAATTGTAGGGGAATCCGAAAATTATCCGAT
TACTCCGAAAGAGCACGGGATCGACTTTCTAATCTCTCAGAGACATCTTTGGTTGCGTTCTTCCAAACAATTGGCGATCC
TTCGGGTGAGAGATAACCTTTCCTTTGCGATTCGTAAATATTTCCACGAACGGGATTTTCTTTTGATCGATACTCCGATT
CTTACCGGGTCAGTAGGAGAAAGTGCCGGAACATTATTTTCCACGGAATATTTCGATCTTGGGAATGCGTATCTTGCTCA
GACCGGGCAACTTTATTTGGAAGCGGCGATTTTTGCGCACAACAAAGTATTTTGTTACGGGCCGACTTTTAGAGCCGAAA
AAAGCAAAACGAGAAGACATTTGACAGAGTTCTGGATGGTGGAAGCGGAGGTTGCATTTGCCGGTCATGCTGACAATTTA
AAATTGCAGGAAGACTTCGTTAAAACCGTCATCAAGGAAACGGTTCAAAATTCTTTACAAGATTTGAAAGTATTGGAAAG
AGATCCGACTCCACTACTTGCATATCTAGAAAAGGATTTCCCGGTGATCGATTATACAAAAGCGTTAGAAATTTTGAAAC
TTAAGGGAGAGGATATCGTTTGGGGAGATGATATCAACTCCGAAAGAGAACAGATGCTTACGATGGAATTCGGAGGTCCG
ATCTTCATCCAAAAATATCCGAGAGAAGCAAAGGCGTTTTATATGAAGGTGAATCCGGATAATCCAAAGACAGTTTTAAA
CGCGGACTTAATCGCGCCTGACGGAGTAGGGGAGATCATCGGAGGGTCGGAAAGAGAGGAGAATTACGAGAACATCATTC
TTAGACTCGAAGAGGAAAAACTTCCCGTGGAATCTTATGATTGGTATTTGGATTTGAGAAAATACGGTTCGGTTCCTCAT
TCCGGTTTTGGGCTCGGTTCGGAAAGGATGATCGCATGGATTTGTGGACTTCAGCACGTTCGAGAGTGTATCCCATTTCC
AAGAATGATGGAAAGATTGTATCCCTGA

Upstream 100 bases:

>100_bases
CTAAGAGAATCGGATCCATACTTCTCAGGATTTAATGTATATCTTCTCTGTCAGGTAAAAAATATCCTTTCCGGTGAAAC
CGAAAGCGTAAAATGAGTCT

Downstream 100 bases:

>100_bases
TTTTTTTCGGGTAATTTTCTCCGGCTCATCCGATAAGAAAAAGAGAGGTATCGTATGGGCCAGAATTTAGCAGTATCCAA
TCCGTCTTCCATCGAAGAAA

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MSEIPIVSNHDLEKYVDRKVVIQGWVHGIRGSNARQFISLRNGGRILQVLAEKEILGEEVFQTVKHLRQETSVSVAGTLV
KNEKSSVGFELIMDRIRIVGESENYPITPKEHGIDFLISQRHLWLRSSKQLAILRVRDNLSFAIRKYFHERDFLLIDTPI
LTGSVGESAGTLFSTEYFDLGNAYLAQTGQLYLEAAIFAHNKVFCYGPTFRAEKSKTRRHLTEFWMVEAEVAFAGHADNL
KLQEDFVKTVIKETVQNSLQDLKVLERDPTPLLAYLEKDFPVIDYTKALEILKLKGEDIVWGDDINSEREQMLTMEFGGP
IFIQKYPREAKAFYMKVNPDNPKTVLNADLIAPDGVGEIIGGSEREENYENIILRLEEEKLPVESYDWYLDLRKYGSVPH
SGFGLGSERMIAWICGLQHVRECIPFPRMMERLYP

Sequences:

>Translated_435_residues
MSEIPIVSNHDLEKYVDRKVVIQGWVHGIRGSNARQFISLRNGGRILQVLAEKEILGEEVFQTVKHLRQETSVSVAGTLV
KNEKSSVGFELIMDRIRIVGESENYPITPKEHGIDFLISQRHLWLRSSKQLAILRVRDNLSFAIRKYFHERDFLLIDTPI
LTGSVGESAGTLFSTEYFDLGNAYLAQTGQLYLEAAIFAHNKVFCYGPTFRAEKSKTRRHLTEFWMVEAEVAFAGHADNL
KLQEDFVKTVIKETVQNSLQDLKVLERDPTPLLAYLEKDFPVIDYTKALEILKLKGEDIVWGDDINSEREQMLTMEFGGP
IFIQKYPREAKAFYMKVNPDNPKTVLNADLIAPDGVGEIIGGSEREENYENIILRLEEEKLPVESYDWYLDLRKYGSVPH
SGFGLGSERMIAWICGLQHVRECIPFPRMMERLYP
>Mature_434_residues
SEIPIVSNHDLEKYVDRKVVIQGWVHGIRGSNARQFISLRNGGRILQVLAEKEILGEEVFQTVKHLRQETSVSVAGTLVK
NEKSSVGFELIMDRIRIVGESENYPITPKEHGIDFLISQRHLWLRSSKQLAILRVRDNLSFAIRKYFHERDFLLIDTPIL
TGSVGESAGTLFSTEYFDLGNAYLAQTGQLYLEAAIFAHNKVFCYGPTFRAEKSKTRRHLTEFWMVEAEVAFAGHADNLK
LQEDFVKTVIKETVQNSLQDLKVLERDPTPLLAYLEKDFPVIDYTKALEILKLKGEDIVWGDDINSEREQMLTMEFGGPI
FIQKYPREAKAFYMKVNPDNPKTVLNADLIAPDGVGEIIGGSEREENYENIILRLEEEKLPVESYDWYLDLRKYGSVPHS
GFGLGSERMIAWICGLQHVRECIPFPRMMERLYP

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI226491502, Length=439, Percent_Identity=35.9908883826879, Blast_Score=261, Evalue=1e-69,
Organism=Homo sapiens, GI4758762, Length=442, Percent_Identity=33.4841628959276, Blast_Score=224, Evalue=2e-58,
Organism=Homo sapiens, GI45439306, Length=456, Percent_Identity=27.8508771929825, Blast_Score=149, Evalue=4e-36,
Organism=Escherichia coli, GI1787161, Length=461, Percent_Identity=37.7440347071584, Blast_Score=287, Evalue=7e-79,
Organism=Escherichia coli, GI1790571, Length=461, Percent_Identity=24.0780911062907, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71984122, Length=439, Percent_Identity=34.3963553530752, Blast_Score=230, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI17556372, Length=410, Percent_Identity=31.219512195122, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17551876, Length=454, Percent_Identity=25.7709251101322, Blast_Score=136, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6321807, Length=442, Percent_Identity=33.0316742081448, Blast_Score=240, Evalue=4e-64,
Organism=Saccharomyces cerevisiae, GI6319872, Length=456, Percent_Identity=32.2368421052632, Blast_Score=211, Evalue=1e-55,
Organism=Saccharomyces cerevisiae, GI6323011, Length=463, Percent_Identity=28.2937365010799, Blast_Score=137, Evalue=4e-33,
Organism=Drosophila melanogaster, GI19922416, Length=442, Percent_Identity=31.447963800905, Blast_Score=208, Evalue=7e-54,
Organism=Drosophila melanogaster, GI19921528, Length=434, Percent_Identity=31.7972350230415, Blast_Score=197, Evalue=9e-51,
Organism=Drosophila melanogaster, GI17136276, Length=477, Percent_Identity=24.9475890985325, Blast_Score=133, Evalue=2e-31,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): SYN_LEPBJ (Q04SB3)

Other databases:

- EMBL:   CP000350
- RefSeq:   YP_800965.1
- ProteinModelPortal:   Q04SB3
- SMR:   Q04SB3
- STRING:   Q04SB3
- GeneID:   4411041
- GenomeReviews:   CP000350_GR
- KEGG:   lbj:LBJ_1650
- eggNOG:   COG0017
- HOGENOM:   HBG745843
- OMA:   EPEMAFC
- PhylomeDB:   Q04SB3
- ProtClustDB:   PRK03932
- BioCyc:   LBOR355277:LBJ_1650-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00534
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00457

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.22

Molecular weight: Translated: 49893; Mature: 49762

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEIPIVSNHDLEKYVDRKVVIQGWVHGIRGSNARQFISLRNGGRILQVLAEKEILGEEV
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHEEEECCCCHHHHHHHHHHHHHHHH
FQTVKHLRQETSVSVAGTLVKNEKSSVGFELIMDRIRIVGESENYPITPKEHGIDFLISQ
HHHHHHHHHHCCHHHEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCHHCCCEEEEEC
RHLWLRSSKQLAILRVRDNLSFAIRKYFHERDFLLIDTPILTGSVGESAGTLFSTEYFDL
CHHEECCCCCEEEEEEECCHHHHHHHHHCCCCEEEEECCEEECCCCCCCCCEEEEHHHHC
GNAYLAQTGQLYLEAAIFAHNKVFCYGPTFRAEKSKTRRHLTEFWMVEAEVAFAGHADNL
CCHHHHCCCHHEEEEEEEECCEEEEECCCCCCHHHHHHHHHHHHHEEEEEEEEECCCCCC
KLQEDFVKTVIKETVQNSLQDLKVLERDPTPLLAYLEKDFPVIDYTKALEILKLKGEDIV
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEHHHHHHHHEECCCEEE
WGDDINSEREQMLTMEFGGPIFIQKYPREAKAFYMKVNPDNPKTVLNADLIAPDGVGEII
ECCCCCCHHHHEEEEECCCEEEEECCCCCCEEEEEEECCCCCCEEEEECEECCCCCHHHC
GGSEREENYENIILRLEEEKLPVESYDWYLDLRKYGSVPHSGFGLGSERMIAWICGLQHV
CCCCCCCCCCEEEEEEECCCCCCCCCHHEEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
RECIPFPRMMERLYP
HHHCCCHHHHHHHCC
>Mature Secondary Structure 
SEIPIVSNHDLEKYVDRKVVIQGWVHGIRGSNARQFISLRNGGRILQVLAEKEILGEEV
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHEEEECCCCHHHHHHHHHHHHHHHH
FQTVKHLRQETSVSVAGTLVKNEKSSVGFELIMDRIRIVGESENYPITPKEHGIDFLISQ
HHHHHHHHHHCCHHHEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCHHCCCEEEEEC
RHLWLRSSKQLAILRVRDNLSFAIRKYFHERDFLLIDTPILTGSVGESAGTLFSTEYFDL
CHHEECCCCCEEEEEEECCHHHHHHHHHCCCCEEEEECCEEECCCCCCCCCEEEEHHHHC
GNAYLAQTGQLYLEAAIFAHNKVFCYGPTFRAEKSKTRRHLTEFWMVEAEVAFAGHADNL
CCHHHHCCCHHEEEEEEEECCEEEEECCCCCCHHHHHHHHHHHHHEEEEEEEEECCCCCC
KLQEDFVKTVIKETVQNSLQDLKVLERDPTPLLAYLEKDFPVIDYTKALEILKLKGEDIV
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEHHHHHHHHEECCCEEE
WGDDINSEREQMLTMEFGGPIFIQKYPREAKAFYMKVNPDNPKTVLNADLIAPDGVGEII
ECCCCCCHHHHEEEEECCCEEEEECCCCCCEEEEEEECCCCCCEEEEECEECCCCCHHHC
GGSEREENYENIILRLEEEKLPVESYDWYLDLRKYGSVPHSGFGLGSERMIAWICGLQHV
CCCCCCCCCCEEEEEEECCCCCCCCCHHEEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
RECIPFPRMMERLYP
HHHCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA