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The map label for this gene is slpA [H]

Identifier: 116328255

GI number: 116328255

Start: 1852950

End: 1853420

Strand: Reverse

Name: slpA [H]

Synonym: LBL_1582

Alternate gene names: 116328255

Gene position: 1853420-1852950 (Counterclockwise)

Preceding gene: 116328256

Following gene: 116328254

Centisome position: 51.28

GC content: 42.25

Gene sequence:

>471_bases
ATGAAAACCAGAGTGATTACTTTTCATTACATCCTTCATGATACAGAAGGCAACTTAATAGATTCTTCCGAAGGCAAAGC
TCCGCTTTCTTATCTGGAAGGAGTCGGGCATATCATTTCGGGTCTGGAAGAAGAAATGAAAAAAATGGGAACCGGCGAAA
AGAGAAAAATCAACGTCTCCGCAGAGAATGCTTACGGCATAAAAGATCCCGATCTCATTTTTGACGTCCCCAGATCCCAG
TTTCCACCCAATGAAGATTTACAAATAGGAATGATGTTTCAAACCGACGAGCCGGATAAGGTTTTTACGATTACCGAACT
TCAAGAAGAATCGGTTATCGTAGATGGAAATCATCCTCTTGCAGGAGTAAATCTAATCTTTGACGTAGAATTGACTGGAA
TTCGTGAAGCTACGGAAGAAGAAATCTCACACGGGCACGTTCACGGAGAAGATGGTCACCACCACCATTGA

Upstream 100 bases:

>100_bases
AACCACCCTGAATTTACCCTGAAAAGTACCTCTAGATTCCGGTATTTTTCTCAAACCGATTCCTGCCAGAATTTTGATTT
TATCTCATTGGGAGCTATTT

Downstream 100 bases:

>100_bases
AAGTTGTGTCCTGGAAAGAAGAATTAAATGCCGCTCAATTGGAAGCAGTCCTTACCCAGGAGGGACCGGTGCTTGTTTTA
GCAGGTGCCGGAACCGGTAA

Product: peptidylprolyl isomerase

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MKTRVITFHYILHDTEGNLIDSSEGKAPLSYLEGVGHIISGLEEEMKKMGTGEKRKINVSAENAYGIKDPDLIFDVPRSQ
FPPNEDLQIGMMFQTDEPDKVFTITELQEESVIVDGNHPLAGVNLIFDVELTGIREATEEEISHGHVHGEDGHHHH

Sequences:

>Translated_156_residues
MKTRVITFHYILHDTEGNLIDSSEGKAPLSYLEGVGHIISGLEEEMKKMGTGEKRKINVSAENAYGIKDPDLIFDVPRSQ
FPPNEDLQIGMMFQTDEPDKVFTITELQEESVIVDGNHPLAGVNLIFDVELTGIREATEEEISHGHVHGEDGHHHH
>Mature_156_residues
MKTRVITFHYILHDTEGNLIDSSEGKAPLSYLEGVGHIISGLEEEMKKMGTGEKRKINVSAENAYGIKDPDLIFDVPRSQ
FPPNEDLQIGMMFQTDEPDKVFTITELQEESVIVDGNHPLAGVNLIFDVELTGIREATEEEISHGHVHGEDGHHHH

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=145, Percent_Identity=43.448275862069, Blast_Score=108, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 17440; Mature: 17440

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS50059 FKBP_PPIASE ; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTRVITFHYILHDTEGNLIDSSEGKAPLSYLEGVGHIISGLEEEMKKMGTGEKRKINVS
CCCEEEEEEEEEECCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
AENAYGIKDPDLIFDVPRSQFPPNEDLQIGMMFQTDEPDKVFTITELQEESVIVDGNHPL
CCCCCCCCCCCEEEECCCCCCCCCCCCEEEEEEECCCCCEEEEEEEECCCEEEEECCCCE
AGVNLIFDVELTGIREATEEEISHGHVHGEDGHHHH
EEEEEEEEEEECCCCHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MKTRVITFHYILHDTEGNLIDSSEGKAPLSYLEGVGHIISGLEEEMKKMGTGEKRKINVS
CCCEEEEEEEEEECCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
AENAYGIKDPDLIFDVPRSQFPPNEDLQIGMMFQTDEPDKVFTITELQEESVIVDGNHPL
CCCCCCCCCCCEEEECCCCCCCCCCCCEEEEEEECCCCCEEEEEEEECCCEEEEECCCCE
AGVNLIFDVELTGIREATEEEISHGHVHGEDGHHHH
EEEEEEEEEEECCCCHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9171380 [H]