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The map label for this gene is hslV

Identifier: 116328184

GI number: 116328184

Start: 1765847

End: 1766389

Strand: Direct

Name: hslV

Synonym: LBL_1508

Alternate gene names: 116328184

Gene position: 1765847-1766389 (Clockwise)

Preceding gene: 116328183

Following gene: 116328185

Centisome position: 48.86

GC content: 42.73

Gene sequence:

>543_bases
ATGCCAGAAAATAAAATTCGTTCCACAACTATTCTTTGTGTACGTAAAAGCGGAAAAGTCGCCATCGGTGGCGACGGTCA
GGTTTCTATGGGAAACACCGTCATGAAAAACACCGCAAAAAAGATCAGAAGACTCTATGACGGGAAAATTCTTTCCGGTT
TTGCAGGCTCGGCTGCGGATGCGTTCACTCTTTTCGAACTTTTTGAAAAAAAGGTTCAAGAATTTGGAGGAAGTCTTTCC
AGAAGCGCTGTGGAACTTGCAAGAGAATGGAGAACGGATCGAATGCTTCGAAAACTTGAGGCACTTTTAATCGTCGCTGA
TAAGGAAGAATCTTTTTTGATTTCGGGAACCGGAGATGTAATTTCACCCGACGAAGGAGTAATCGCGATTGGTTCCGGAG
GTAGCTATGCATTGGCAGCGGCTAAGGCTCTTTACGATCATACGGATTTGTCCGCGAGAGAAATTGTAGAATCATCCATG
AAAATCGCAGCAAACATTTGTATTTATACGAACGATCACATTACCCTAGAAGAAATTCTTTAA

Upstream 100 bases:

>100_bases
GTACAGGAATTACTCGGACATTCTTCTCTTTCCACAACTCAGATTTATTTGAGTGTAAGTAAGGAAAAAATCAAAGAAGT
TTATAGAAAGGCTCATCCTC

Downstream 100 bases:

>100_bases
AGATAAAAATATATGACAGACTACTCCAAAGACCAGGACCTTATGTTGCCGATCGAAGAAGAGCTAACTCCTCGACAAAT
CGTCGCAAAATTGGACGAAC

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 180; Mature: 179

Protein sequence:

>180_residues
MPENKIRSTTILCVRKSGKVAIGGDGQVSMGNTVMKNTAKKIRRLYDGKILSGFAGSAADAFTLFELFEKKVQEFGGSLS
RSAVELAREWRTDRMLRKLEALLIVADKEESFLISGTGDVISPDEGVIAIGSGGSYALAAAKALYDHTDLSAREIVESSM
KIAANICIYTNDHITLEEIL

Sequences:

>Translated_180_residues
MPENKIRSTTILCVRKSGKVAIGGDGQVSMGNTVMKNTAKKIRRLYDGKILSGFAGSAADAFTLFELFEKKVQEFGGSLS
RSAVELAREWRTDRMLRKLEALLIVADKEESFLISGTGDVISPDEGVIAIGSGGSYALAAAKALYDHTDLSAREIVESSM
KIAANICIYTNDHITLEEIL
>Mature_179_residues
PENKIRSTTILCVRKSGKVAIGGDGQVSMGNTVMKNTAKKIRRLYDGKILSGFAGSAADAFTLFELFEKKVQEFGGSLSR
SAVELAREWRTDRMLRKLEALLIVADKEESFLISGTGDVISPDEGVIAIGSGGSYALAAAKALYDHTDLSAREIVESSMK
IAANICIYTNDHITLEEIL

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily

Homologues:

Organism=Escherichia coli, GI1790367, Length=171, Percent_Identity=61.4035087719298, Blast_Score=224, Evalue=2e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLV_LEPBJ (Q04TA2)

Other databases:

- EMBL:   CP000350
- RefSeq:   YP_800626.1
- ProteinModelPortal:   Q04TA2
- SMR:   Q04TA2
- STRING:   Q04TA2
- GeneID:   4410690
- GenomeReviews:   CP000350_GR
- KEGG:   lbj:LBJ_1283
- eggNOG:   COG5405
- HOGENOM:   HBG288822
- OMA:   AADICVY
- PhylomeDB:   Q04TA2
- ProtClustDB:   PRK05456
- BioCyc:   LBOR355277:LBJ_1283-MONOMER
- HAMAP:   MF_00248
- InterPro:   IPR022281
- InterPro:   IPR001353
- TIGRFAMs:   TIGR03692

Pfam domain/function: PF00227 Proteasome

EC number: 3.4.25.-

Molecular weight: Translated: 19478; Mature: 19346

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: ACT_SITE 9-9

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPENKIRSTTILCVRKSGKVAIGGDGQVSMGNTVMKNTAKKIRRLYDGKILSGFAGSAAD
CCCCHHCCEEEEEEECCCCEEECCCCCEECCHHHHHHHHHHHHHHHCCCEECCCCCCHHH
AFTLFELFEKKVQEFGGSLSRSAVELAREWRTDRMLRKLEALLIVADKEESFLISGTGDV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEECCCCC
ISPDEGVIAIGSGGSYALAAAKALYDHTDLSAREIVESSMKIAANICIYTNDHITLEEIL
CCCCCCEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHEEEEEEECCCEEHHHCC
>Mature Secondary Structure 
PENKIRSTTILCVRKSGKVAIGGDGQVSMGNTVMKNTAKKIRRLYDGKILSGFAGSAAD
CCCHHCCEEEEEEECCCCEEECCCCCEECCHHHHHHHHHHHHHHHCCCEECCCCCCHHH
AFTLFELFEKKVQEFGGSLSRSAVELAREWRTDRMLRKLEALLIVADKEESFLISGTGDV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEECCCCC
ISPDEGVIAIGSGGSYALAAAKALYDHTDLSAREIVESSMKIAANICIYTNDHITLEEIL
CCCCCCEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHEEEEEEECCCEEHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA