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The map label for this gene is clpX

Identifier: 116327863

GI number: 116327863

Start: 1347133

End: 1348395

Strand: Direct

Name: clpX

Synonym: LBL_1142

Alternate gene names: 116327863

Gene position: 1347133-1348395 (Clockwise)

Preceding gene: 116327862

Following gene: 116327866

Centisome position: 37.27

GC content: 42.04

Gene sequence:

>1263_bases
TTGGCCAAGAAAACACCGGGAACCAACGGTAAACAAAAACTATTCTGCTCTTTTTGCGGAAAGGAACAGGATGCGGTAAA
ACGTTTAGTCGCCGGGCCAGGAGTTTATATCTGCGACGAATGTATTTCTCTTTGTAATGAAATTATCGCGGAAGACCACG
AACACTCTCATGAAAAGTCGGAAGTATTTAGCGAGATTCCAAATCCCGTAGATATCAAATCCATTTTGGATCAATATGTC
ATCGGACAGGATCACGCGAAAAAGGCTCTTTCCGTAGCGGTTTACAATCACTATAAAAGAGTGAATCTCAAAGAAAAGAA
ATCCGATGTGGAAATCGAAAAATCGAATATTCTTTTGATTGGACCGACAGGAAGCGGTAAAACTCTTCTGGCTCAGACTC
TTGCAAGGATCATCAAAGTCCCTTTTGCAATTGTAGATGCGACTGCTTTGACCGAAGCGGGTTACGTGGGAGAGGATGTG
GAGAATATTATCCTTAAATTGATCCAGAACGCCGAAAATGATATCAAAAAAGCGGAAATCGGAATCATCTATATAGACGA
GGTGGATAAAATTGCGCGTAAGTCCGATAGTGCATCCATTACGAGAGACGTGAGTGGGGAAGGAGTACAACAGGCGCTTC
TGAAAATTATCGAAGGAACGATCGCTAATGTTCCTCCGCAAGGCGGAAGAAAACATCCGCATCAGGAATATTTGCAAGTT
GATACAAAGAACATTCTTTTTATTCTGGGTGGGGCCTTTGTGGATCTTCCGAATATCATCAAGTCCAGAACCGGAGTCAA
GACGATCGGTTTCGGTTCAGAGGAACAAAGGATTCAAGCGGAAAACAAGGATACTCTGATGGAACAGGTGATTCCAGAGG
ATTTGATTAAGTTCGGGCTGATTCCTGAATTTATTGGAAGACTTCCTATTGTTGCGACTCTTCAAGAGTTGAATGTGGAT
ATGCTGAAGCAGATTTTCCGCGAACCGAAAAACTCCGTTCTCAAACAATACACTCGCCTTCTTGAATTGGAAAATGTAAA
ACTTACTTTTCATGAGGACGCGATCGATAAAATCGCCGAACTTGCGATCAAAAGAGAATCCGGTGCTCGAGGGCTTAGGG
CGATTGTTGAAAATATCATGTTAGATCTGATGTTCGACATTCCATCCCGTAAAGATATCGAAGAGGTAATTATCACTGCG
GAAGTAATTACCGATCGAGTGACTCCTACTTTAATTCTCAAAAAAGAATCTAAGATCGCTTAA

Upstream 100 bases:

>100_bases
AGAAATTTTTACATGACGGCGGAAGAAGCAAAAAATTACGGAATCATAGATACGGTCATTCAGATTGATCGTAAATAAGT
TAAATTAGAGGAGTGATCCC

Downstream 100 bases:

>100_bases
AGTCTTTCCCGAAACTTGAAGAGAATTCAGTGATAATTAACGTGAGCAGGGCGTAACGAAAGCGATTGTTATGCTGATCC
CATAAAGAGTAGTATTTTAG

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MAKKTPGTNGKQKLFCSFCGKEQDAVKRLVAGPGVYICDECISLCNEIIAEDHEHSHEKSEVFSEIPNPVDIKSILDQYV
IGQDHAKKALSVAVYNHYKRVNLKEKKSDVEIEKSNILLIGPTGSGKTLLAQTLARIIKVPFAIVDATALTEAGYVGEDV
ENIILKLIQNAENDIKKAEIGIIYIDEVDKIARKSDSASITRDVSGEGVQQALLKIIEGTIANVPPQGGRKHPHQEYLQV
DTKNILFILGGAFVDLPNIIKSRTGVKTIGFGSEEQRIQAENKDTLMEQVIPEDLIKFGLIPEFIGRLPIVATLQELNVD
MLKQIFREPKNSVLKQYTRLLELENVKLTFHEDAIDKIAELAIKRESGARGLRAIVENIMLDLMFDIPSRKDIEEVIITA
EVITDRVTPTLILKKESKIA

Sequences:

>Translated_420_residues
MAKKTPGTNGKQKLFCSFCGKEQDAVKRLVAGPGVYICDECISLCNEIIAEDHEHSHEKSEVFSEIPNPVDIKSILDQYV
IGQDHAKKALSVAVYNHYKRVNLKEKKSDVEIEKSNILLIGPTGSGKTLLAQTLARIIKVPFAIVDATALTEAGYVGEDV
ENIILKLIQNAENDIKKAEIGIIYIDEVDKIARKSDSASITRDVSGEGVQQALLKIIEGTIANVPPQGGRKHPHQEYLQV
DTKNILFILGGAFVDLPNIIKSRTGVKTIGFGSEEQRIQAENKDTLMEQVIPEDLIKFGLIPEFIGRLPIVATLQELNVD
MLKQIFREPKNSVLKQYTRLLELENVKLTFHEDAIDKIAELAIKRESGARGLRAIVENIMLDLMFDIPSRKDIEEVIITA
EVITDRVTPTLILKKESKIA
>Mature_419_residues
AKKTPGTNGKQKLFCSFCGKEQDAVKRLVAGPGVYICDECISLCNEIIAEDHEHSHEKSEVFSEIPNPVDIKSILDQYVI
GQDHAKKALSVAVYNHYKRVNLKEKKSDVEIEKSNILLIGPTGSGKTLLAQTLARIIKVPFAIVDATALTEAGYVGEDVE
NIILKLIQNAENDIKKAEIGIIYIDEVDKIARKSDSASITRDVSGEGVQQALLKIIEGTIANVPPQGGRKHPHQEYLQVD
TKNILFILGGAFVDLPNIIKSRTGVKTIGFGSEEQRIQAENKDTLMEQVIPEDLIKFGLIPEFIGRLPIVATLQELNVDM
LKQIFREPKNSVLKQYTRLLELENVKLTFHEDAIDKIAELAIKRESGARGLRAIVENIMLDLMFDIPSRKDIEEVIITAE
VITDRVTPTLILKKESKIA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=332, Percent_Identity=46.9879518072289, Blast_Score=287, Evalue=1e-77,
Organism=Escherichia coli, GI1786642, Length=417, Percent_Identity=59.2326139088729, Blast_Score=488, Evalue=1e-139,
Organism=Escherichia coli, GI1790366, Length=104, Percent_Identity=45.1923076923077, Blast_Score=96, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI71982905, Length=314, Percent_Identity=44.2675159235669, Blast_Score=269, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI71982908, Length=314, Percent_Identity=44.2675159235669, Blast_Score=269, Evalue=3e-72,
Organism=Caenorhabditis elegans, GI71988663, Length=410, Percent_Identity=35.8536585365854, Blast_Score=234, Evalue=5e-62,
Organism=Caenorhabditis elegans, GI71988660, Length=250, Percent_Identity=39.2, Blast_Score=163, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6319704, Length=412, Percent_Identity=39.5631067961165, Blast_Score=269, Evalue=8e-73,
Organism=Drosophila melanogaster, GI24648291, Length=322, Percent_Identity=46.583850931677, Blast_Score=298, Evalue=6e-81,
Organism=Drosophila melanogaster, GI24648289, Length=322, Percent_Identity=46.583850931677, Blast_Score=297, Evalue=8e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_LEPBJ (Q04TR3)

Other databases:

- EMBL:   CP000350
- RefSeq:   YP_800465.1
- ProteinModelPortal:   Q04TR3
- STRING:   Q04TR3
- GeneID:   4411829
- GenomeReviews:   CP000350_GR
- KEGG:   lbj:LBJ_1085
- eggNOG:   COG1219
- HOGENOM:   HBG745965
- OMA:   CGKSQEQ
- PhylomeDB:   Q04TR3
- ProtClustDB:   PRK05342
- BioCyc:   LBOR355277:LBJ_1085-MONOMER
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 46666; Mature: 46534

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKTPGTNGKQKLFCSFCGKEQDAVKRLVAGPGVYICDECISLCNEIIAEDHEHSHEKS
CCCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHH
EVFSEIPNPVDIKSILDQYVIGQDHAKKALSVAVYNHYKRVNLKEKKSDVEIEKSNILLI
HHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHCCCCCEEEECCEEEE
GPTGSGKTLLAQTLARIIKVPFAIVDATALTEAGYVGEDVENIILKLIQNAENDIKKAEI
ECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHE
GIIYIDEVDKIARKSDSASITRDVSGEGVQQALLKIIEGTIANVPPQGGRKHPHQEYLQV
EEEEECCHHHHHHCCCCCHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
DTKNILFILGGAFVDLPNIIKSRTGVKTIGFGSEEQRIQAENKDTLMEQVIPEDLIKFGL
CCCCEEEEECCHHHHHHHHHHHCCCCEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHCC
IPEFIGRLPIVATLQELNVDMLKQIFREPKNSVLKQYTRLLELENVKLTFHEDAIDKIAE
HHHHHCCCCHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHH
LAIKRESGARGLRAIVENIMLDLMFDIPSRKDIEEVIITAEVITDRVTPTLILKKESKIA
HHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCC
>Mature Secondary Structure 
AKKTPGTNGKQKLFCSFCGKEQDAVKRLVAGPGVYICDECISLCNEIIAEDHEHSHEKS
CCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHH
EVFSEIPNPVDIKSILDQYVIGQDHAKKALSVAVYNHYKRVNLKEKKSDVEIEKSNILLI
HHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHCCCCCEEEECCEEEE
GPTGSGKTLLAQTLARIIKVPFAIVDATALTEAGYVGEDVENIILKLIQNAENDIKKAEI
ECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHE
GIIYIDEVDKIARKSDSASITRDVSGEGVQQALLKIIEGTIANVPPQGGRKHPHQEYLQV
EEEEECCHHHHHHCCCCCHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
DTKNILFILGGAFVDLPNIIKSRTGVKTIGFGSEEQRIQAENKDTLMEQVIPEDLIKFGL
CCCCEEEEECCHHHHHHHHHHHCCCCEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHCC
IPEFIGRLPIVATLQELNVDMLKQIFREPKNSVLKQYTRLLELENVKLTFHEDAIDKIAE
HHHHHCCCCHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHH
LAIKRESGARGLRAIVENIMLDLMFDIPSRKDIEEVIITAEVITDRVTPTLILKKESKIA
HHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA