| Definition | Leptospira borgpetersenii serovar Hardjo-bovis L550 chromosome 1, complete sequence. |
|---|---|
| Accession | NC_008508 |
| Length | 3,614,446 |
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The map label for this gene is dxs
Identifier: 116327686
GI number: 116327686
Start: 1076659
End: 1078566
Strand: Direct
Name: dxs
Synonym: LBL_0932
Alternate gene names: 116327686
Gene position: 1076659-1078566 (Clockwise)
Preceding gene: 116327685
Following gene: 116327687
Centisome position: 29.79
GC content: 45.55
Gene sequence:
>1908_bases ATGCAACAGGAATCAACTCTGCTGGATAAGATTGATTATCCAGCCGATCTCAGAAACATACCGTTGGAAAAACTTCCGCA GGTCTGTAAAGAGGTTCGGAATTACATCATCGATACTCTATCGGGAGTAGGCGGGCATTTTGCAAGTAATCTGGGAGTCG TGGAGCTAACGGTAGCGCTTCACTACGTATTCGACACACCAAAGGATCGATTGATCTGGGATGTGGGCCACCAAACGTAT CCACATAAGATTCTCACGGGAAGAAAAGACAGACTCAAAACCGTACGAAAGTTTAACGGACTTTCCGGGTTTCCGAAAAG GGAGGAATCTCCTTATGACCTTTATAACACAGGGCATGCGGGAACTTCGATATCGCAAGCGCTCGGAGAAGCCGCTGCCC GGGATCTAACAAAGGGAGAGGATTACAGTGTAGTTGCCATTATCGGAGACGCGTCGATTGCAACAGGAATGGCACTCGAA GCGATGAATCACGCCGGTCATTTAAAGAAGGACATGATCGTAATCTTAAACGATAATTACATGTCAATCTCGAAGAATGT GGGTTCCATTTCCAACTACCTCAACAACATCATAACATCTCATTTTTACAATCACTGGAAGAGAGTATTTTACACTTTTT TAAAGTGGTTGCCTATCGTTGGGCCCGCGGCCGAGAGATTTTTCAAAAAAGTGGAGAAGGGATTCAAAGACGTTCTAACG CCGGGCGGACTATTCGAGGATTTGGGATTCGGATATATCGGGCCTGAAGACGGGCATGACGTGATTCGACTCGTGAACAT GCTCGCAAAAGTAAAAAAAATGAAGGGACCTATATTACTTCACCTAATCACGCAAAAGGGGAAAGGATACGATCCGGCGG AGAGGGATCCGATCAAGTATCACGGAGTAACACCGTTTCGAAAAGAGGACGGAGCGATGGACAGTGGAGATACTTCCAAG ATCGCATACAGTAAGATTGTAGGAAGGATGTTGTCGATTTTAACGGAAGCAAATCCTAAGATTGCGGCAATCACACCGGC GATGATCGAAGGAAGTGGATTAAAAGAATACGCCGAAAAATATCCTGACCACCTTTTTGATGTAGGGATAGCAGAGCAAC ATTCCGTAGCGTTTGCCGGAGCGATGACGAACGGAAGTATCATTCCTTATATGTGTATTTACTCGACGTTTTTAACGAGG GCAATAGATCAGCTCGTCCAGGATGTATCATTGATGAATCTACCTGTTCGGTTTGTGATTGATCGTGCGGGGTGTGTGGG GCCGGACGGGGAAACGCACCAAGGACTTTTCGATTTAGGATATCTGCTCGGTTTGCCGAACATGGATGTATTTGTTCCGT CTAACGGACAGGACATGATCGATTCACTTCGATGGATGGAAACGTACGACAAGGCTCCGATTGCAATTCGATTCCCGAAG GCGAATGTGGACTTGAAGACTTTGGATTTTTACAAAGAAGTCGATCTTCGACCTGGAACATTTCGAGTTCTCAAAAGAGG AACGGATCTTGCTCTTTTATCGATCGGATCCATGATCGACGAAGCCAAAAAAGCGACCGAAATTCTGGAAAGTGCGGGCT TCAGCGTAACCCTCATCGATCTCATATGGTTACGACCACTTGGAGTGGAAGCGCTCAACGAAGAATTATCTAATGTGAGA CGTTTTGTGATAATAGACGAAAGTTATGTCGACGCTGGAGCTTCCGGATATCTGCTCAATAGGATTCTTCCTGAAAATTT ATCGAAATATGTCAAAACGTTCGGATTTCCGCCGGAGCCGATACATCACGGAGAAAGGAAAGAAATTATCCAAGCGTATA GGTTGGATGGGGCATCGATCGCGGAGAGTGTAGCGGATGTATTGAAAAAAAACTTAATCAAGCCGTGA
Upstream 100 bases:
>100_bases ATCTACGAATTATTGGATTTAGTGAACGAGGAAGACCTGAAACTATTAAGAAAACCTTTGCAGGTGAATTGAAAAATTAA TAAAATTATAGAAAGTTTTC
Downstream 100 bases:
>100_bases CCATTCCAAACCGAAAATAAAAATAAAAACGGGTTAAGGAATTGGAAAACATTACTCCTTCAGATTTTTTAGAAGCGGCG AAATATTTTTATAAAAAAGG
Product: 1-deoxy-D-xylulose-5-phosphate synthase
Products: NA
Alternate protein names: 1-deoxyxylulose-5-phosphate synthase; DXP synthase; DXPS
Number of amino acids: Translated: 635; Mature: 635
Protein sequence:
>635_residues MQQESTLLDKIDYPADLRNIPLEKLPQVCKEVRNYIIDTLSGVGGHFASNLGVVELTVALHYVFDTPKDRLIWDVGHQTY PHKILTGRKDRLKTVRKFNGLSGFPKREESPYDLYNTGHAGTSISQALGEAAARDLTKGEDYSVVAIIGDASIATGMALE AMNHAGHLKKDMIVILNDNYMSISKNVGSISNYLNNIITSHFYNHWKRVFYTFLKWLPIVGPAAERFFKKVEKGFKDVLT PGGLFEDLGFGYIGPEDGHDVIRLVNMLAKVKKMKGPILLHLITQKGKGYDPAERDPIKYHGVTPFRKEDGAMDSGDTSK IAYSKIVGRMLSILTEANPKIAAITPAMIEGSGLKEYAEKYPDHLFDVGIAEQHSVAFAGAMTNGSIIPYMCIYSTFLTR AIDQLVQDVSLMNLPVRFVIDRAGCVGPDGETHQGLFDLGYLLGLPNMDVFVPSNGQDMIDSLRWMETYDKAPIAIRFPK ANVDLKTLDFYKEVDLRPGTFRVLKRGTDLALLSIGSMIDEAKKATEILESAGFSVTLIDLIWLRPLGVEALNEELSNVR RFVIIDESYVDAGASGYLLNRILPENLSKYVKTFGFPPEPIHHGERKEIIQAYRLDGASIAESVADVLKKNLIKP
Sequences:
>Translated_635_residues MQQESTLLDKIDYPADLRNIPLEKLPQVCKEVRNYIIDTLSGVGGHFASNLGVVELTVALHYVFDTPKDRLIWDVGHQTY PHKILTGRKDRLKTVRKFNGLSGFPKREESPYDLYNTGHAGTSISQALGEAAARDLTKGEDYSVVAIIGDASIATGMALE AMNHAGHLKKDMIVILNDNYMSISKNVGSISNYLNNIITSHFYNHWKRVFYTFLKWLPIVGPAAERFFKKVEKGFKDVLT PGGLFEDLGFGYIGPEDGHDVIRLVNMLAKVKKMKGPILLHLITQKGKGYDPAERDPIKYHGVTPFRKEDGAMDSGDTSK IAYSKIVGRMLSILTEANPKIAAITPAMIEGSGLKEYAEKYPDHLFDVGIAEQHSVAFAGAMTNGSIIPYMCIYSTFLTR AIDQLVQDVSLMNLPVRFVIDRAGCVGPDGETHQGLFDLGYLLGLPNMDVFVPSNGQDMIDSLRWMETYDKAPIAIRFPK ANVDLKTLDFYKEVDLRPGTFRVLKRGTDLALLSIGSMIDEAKKATEILESAGFSVTLIDLIWLRPLGVEALNEELSNVR RFVIIDESYVDAGASGYLLNRILPENLSKYVKTFGFPPEPIHHGERKEIIQAYRLDGASIAESVADVLKKNLIKP >Mature_635_residues MQQESTLLDKIDYPADLRNIPLEKLPQVCKEVRNYIIDTLSGVGGHFASNLGVVELTVALHYVFDTPKDRLIWDVGHQTY PHKILTGRKDRLKTVRKFNGLSGFPKREESPYDLYNTGHAGTSISQALGEAAARDLTKGEDYSVVAIIGDASIATGMALE AMNHAGHLKKDMIVILNDNYMSISKNVGSISNYLNNIITSHFYNHWKRVFYTFLKWLPIVGPAAERFFKKVEKGFKDVLT PGGLFEDLGFGYIGPEDGHDVIRLVNMLAKVKKMKGPILLHLITQKGKGYDPAERDPIKYHGVTPFRKEDGAMDSGDTSK IAYSKIVGRMLSILTEANPKIAAITPAMIEGSGLKEYAEKYPDHLFDVGIAEQHSVAFAGAMTNGSIIPYMCIYSTFLTR AIDQLVQDVSLMNLPVRFVIDRAGCVGPDGETHQGLFDLGYLLGLPNMDVFVPSNGQDMIDSLRWMETYDKAPIAIRFPK ANVDLKTLDFYKEVDLRPGTFRVLKRGTDLALLSIGSMIDEAKKATEILESAGFSVTLIDLIWLRPLGVEALNEELSNVR RFVIIDESYVDAGASGYLLNRILPENLSKYVKTFGFPPEPIHHGERKEIIQAYRLDGASIAESVADVLKKNLIKP
Specific function: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
COG id: COG1154
COG function: function code HI; Deoxyxylulose-5-phosphate synthase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the transketolase family. DXPS subfamily
Homologues:
Organism=Homo sapiens, GI205277463, Length=655, Percent_Identity=20.9160305343511, Blast_Score=79, Evalue=1e-14, Organism=Homo sapiens, GI4507521, Length=655, Percent_Identity=20.9160305343511, Blast_Score=79, Evalue=1e-14, Organism=Escherichia coli, GI1786622, Length=617, Percent_Identity=42.6256077795786, Blast_Score=502, Evalue=1e-143, Organism=Caenorhabditis elegans, GI17539652, Length=407, Percent_Identity=24.8157248157248, Blast_Score=83, Evalue=4e-16, Organism=Drosophila melanogaster, GI24666278, Length=589, Percent_Identity=21.9015280135823, Blast_Score=84, Evalue=2e-16, Organism=Drosophila melanogaster, GI45551847, Length=275, Percent_Identity=26.1818181818182, Blast_Score=73, Evalue=6e-13, Organism=Drosophila melanogaster, GI45550715, Length=275, Percent_Identity=26.1818181818182, Blast_Score=73, Evalue=6e-13, Organism=Drosophila melanogaster, GI24645119, Length=320, Percent_Identity=24.0625, Blast_Score=73, Evalue=7e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): DXS_LEPBJ (Q04U59)
Other databases:
- EMBL: CP000350 - RefSeq: YP_800319.1 - ProteinModelPortal: Q04U59 - SMR: Q04U59 - STRING: Q04U59 - GeneID: 4409813 - GenomeReviews: CP000350_GR - KEGG: lbj:LBJ_0917 - eggNOG: COG1154 - HOGENOM: HBG571647 - OMA: QRFPDRY - PhylomeDB: Q04U59 - ProtClustDB: PRK05444 - BioCyc: LBOR355277:LBJ_0917-MONOMER - HAMAP: MF_00315 - InterPro: IPR005477 - InterPro: IPR009014 - InterPro: IPR015941 - InterPro: IPR005475 - InterPro: IPR005476 - InterPro: IPR005474 - Gene3D: G3DSA:3.40.50.920 - SMART: SM00861 - TIGRFAMs: TIGR00204
Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N; SSF52922 Transketo_C_like
EC number: =2.2.1.7
Molecular weight: Translated: 70592; Mature: 70592
Theoretical pI: Translated: 6.77; Mature: 6.77
Prosite motif: PS00801 TRANSKETOLASE_1; PS00802 TRANSKETOLASE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 2.7 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MQQESTLLDKIDYPADLRNIPLEKLPQVCKEVRNYIIDTLSGVGGHFASNLGVVELTVAL CCCHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEHHHHH HYVFDTPKDRLIWDVGHQTYPHKILTGRKDRLKTVRKFNGLSGFPKREESPYDLYNTGHA HHHHCCCCCCEEEECCCCCCCHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC GTSISQALGEAAARDLTKGEDYSVVAIIGDASIATGMALEAMNHAGHLKKDMIVILNDNY CCHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCEEEEECCCC MSISKNVGSISNYLNNIITSHFYNHWKRVFYTFLKWLPIVGPAAERFFKKVEKGFKDVLT EEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC PGGLFEDLGFGYIGPEDGHDVIRLVNMLAKVKKMKGPILLHLITQKGKGYDPAERDPIKY CCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCEE HGVTPFRKEDGAMDSGDTSKIAYSKIVGRMLSILTEANPKIAAITPAMIEGSGLKEYAEK CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHCCCCHHHHHHH YPDHLFDVGIAEQHSVAFAGAMTNGSIIPYMCIYSTFLTRAIDQLVQDVSLMNLPVRFVI CCHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEE DRAGCVGPDGETHQGLFDLGYLLGLPNMDVFVPSNGQDMIDSLRWMETYDKAPIAIRFPK ECCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHCCCCEEEECCC ANVDLKTLDFYKEVDLRPGTFRVLKRGTDLALLSIGSMIDEAKKATEILESAGFSVTLID CCCCHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEHH LIWLRPLGVEALNEELSNVRRFVIIDESYVDAGASGYLLNRILPENLSKYVKTFGFPPEP HHHHCCCCHHHHHHHHHHCEEEEEEECHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC IHHGERKEIIQAYRLDGASIAESVADVLKKNLIKP CCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCC >Mature Secondary Structure MQQESTLLDKIDYPADLRNIPLEKLPQVCKEVRNYIIDTLSGVGGHFASNLGVVELTVAL CCCHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEHHHHH HYVFDTPKDRLIWDVGHQTYPHKILTGRKDRLKTVRKFNGLSGFPKREESPYDLYNTGHA HHHHCCCCCCEEEECCCCCCCHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC GTSISQALGEAAARDLTKGEDYSVVAIIGDASIATGMALEAMNHAGHLKKDMIVILNDNY CCHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCEEEEECCCC MSISKNVGSISNYLNNIITSHFYNHWKRVFYTFLKWLPIVGPAAERFFKKVEKGFKDVLT EEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC PGGLFEDLGFGYIGPEDGHDVIRLVNMLAKVKKMKGPILLHLITQKGKGYDPAERDPIKY CCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCEE HGVTPFRKEDGAMDSGDTSKIAYSKIVGRMLSILTEANPKIAAITPAMIEGSGLKEYAEK CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHCCCCHHHHHHH YPDHLFDVGIAEQHSVAFAGAMTNGSIIPYMCIYSTFLTRAIDQLVQDVSLMNLPVRFVI CCHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEE DRAGCVGPDGETHQGLFDLGYLLGLPNMDVFVPSNGQDMIDSLRWMETYDKAPIAIRFPK ECCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHCCCCEEEECCC ANVDLKTLDFYKEVDLRPGTFRVLKRGTDLALLSIGSMIDEAKKATEILESAGFSVTLID CCCCHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEHH LIWLRPLGVEALNEELSNVRRFVIIDESYVDAGASGYLLNRILPENLSKYVKTFGFPPEP HHHHCCCCHHHHHHHHHHCEEEEEEECHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC IHHGERKEIIQAYRLDGASIAESVADVLKKNLIKP CCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA