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The map label for this gene is btuB [H]

Identifier: 116327629

GI number: 116327629

Start: 1002169

End: 1004301

Strand: Direct

Name: btuB [H]

Synonym: LBL_0862

Alternate gene names: 116327629

Gene position: 1002169-1004301 (Clockwise)

Preceding gene: 116327628

Following gene: 116327630

Centisome position: 27.73

GC content: 42.99

Gene sequence:

>2133_bases
ATGAGATTATTTAATTACATTTTAATTTTAGAATATTCTATAATTTTGTTATTTTCTATTTTTGTTTCCGGGATTGTTGC
TCAAGATAATTCAGATTCCATGATCGTTCAAAAAGCGGAAACGGTTCGGGTGATCGGAAAGGTTTCCGATTCTGGTTCCC
AAAACTTTCGATCCAACCCGAGCGGATTTCAATCCGCGATTAAACTCGATGAAACGTCGGAACGTTATACGTCATTACCG
GAGGTTTTGGAAAGAGAGGCCGGACTGAGGGTCAGATCTTTTGGAGGACTCGGCTCTTATTCCACGCTTTCCATCCGAGG
CACAAACCCGAATCAATCTAGGATCTATTTGGATGGAATTCCGCTGAATAATTCCCAAGGTGGGGAAGTCAATCTTGCCG
ATCTTCCTTTCGACAGTTTGGAAAGTGTGGAGGTTTACAGGTCCGGAAATCCGATCGGTTTTTCGGGTTCTGCGATCGGA
GGTTCGGTCAATCTCGTCACGAGAAAGGATACGGGAAAACCCAGAACGAGAGTCAATCTAGGAGGCGGTTCGTTTAACAC
GGGCAAGGCGAGCGTTTCTCATACCGGAACGTACAATGGAATCGGAGCGAGTTTTTTGGCGCTCGGCGAAAAATCGGATC
AGAACTTTTCTTTTAAAAACGATCACGGAACCGTAGTTTTAAACACGTTAGACGACACGATTGATCGAAGGAGGAATGCG
GCATTTGAAAGAGCGGCGCTTTTTGGAACGCTCAAATATCAAATGGGCAAAACCGAACTAAAATTATTAAACGACTTCAA
TCATAGAATTCACGGACTTCCGGGACCGGGTTCCAATCAGACGAATCGGGTTCATAGAAAATACGATCGATACACAGGTT
CTTTTGCAACGGATACGAAAGGTTTATTCGTGGATTTTTTTCGTCTTGAGACTAGAAGTTTTTATACCGCGGCCAAGGAC
GATCTTTTCGATCCTGGCTCCGAATTCTCCAAAGGAACTCCGAATTCCAGAGCGGAAATCCGACAGGCGGGGATTCAAAT
CATGCCGACTTTATATCTAACGGATTATTATCAAATTCTAAGAGTGTTTGTTTCTTTAGAAAGGGAATCCTTTGATCGCA
ATAGGTTGACCCCTTCCAACGTTATCGGAAGAGTGGAACCTCTAAAAGAAAGGACGTATTCTTCCTTTCGTTTGGAAGAC
GAAGTCCGTCTTTGGAATGCGAAGGTTCTTTTGGTTCCTTCTGTGACTTGGGATCATTATAGGGACCGTTTCCCTTCGGA
GGAACCTTGGTATAGAAGGCAGGATCTTTTTGCGAGCGATAGTAAGAAAATCACATTCACAAATCCTAAATTAGGTTTTG
TATGGAAGTTGTTCGAAAGGGAAGCTTGGGACGTTCAATTTCAAGCAAACGTTTCCAGACAATATAGAATTCCTTCCTTT
TTGGAAATGTTCGGAGAACAGGGGAGCATCATTGCAAACCCGAATCTGAGGCCGGAACGAAGCGGCAACGGGGACGCTGG
ATTTGTGTTCAAAACGAATCATTCTTACTTAAAAACGAAAACGAGTGTTTCTTATTTTTCCAAAGATATCAAAGATATGA
TTTTGTTTCTTCCGAATTCTCAGTTTACTCTGAGGCCGGAGAACGTGGATTCCGCACGGATCAGAGGGATCGAGTTCTCC
CATAGGGTAGATTGGAAATATGGGATTAAATTTTTGTTCAACTATACCTATCAGGATGCGATCAACACTTCCTCTTCCGT
GTATCTGCGCGGAAAAATTCTTCCTTTGAGGTCGAGACACGAGTTTGCGAGTATTCTTTCTTGGAAAAGGAAGAGATTGG
AAACAGGGATCGAATTGTTGTATATCGGCGCGGTGTTTCGCGATAGAACGAACGAATACATCAACTATATCCCGGAGAGA
CAGATTTGGAACTATTTTTTCACCTGGATTCTTGATTCGGAACCGGGAGAGTCCGTAAAAAATTCTTTGGGAGATTTAAA
GGAATCCGCTCCTTCCAGGGAAGTTTTACTTACTTTTGAAACGAAGAATTTTACGGATCGAAGAGTTTCCGATCTGATCG
GTTATCCGCTTCCGGGTAGAAGTTGGTACGTGACTTTGAGTATGAGATTTTGA

Upstream 100 bases:

>100_bases
CTGACGGGACTTTCGGGAGTTAAAGTCGGGTTTGAAAAATAGGCTTTCATCCGCTCGGATTTTCCGGTTTTTCTTCCCGG
CGTTTTCAATCGGGCGAAAA

Downstream 100 bases:

>100_bases
TATGAGATTAAAGATTAATATTTTTATAATATTCTTTTTTTTGAATGTATATTGTCGGGATATTCAAAAGCCGTCTTTTC
TGAGTCTTCTTCTGATTCAA

Product: cobalamin receptor protein

Products: NA

Alternate protein names: Cobalamin receptor; Outer membrane cobalamin translocator [H]

Number of amino acids: Translated: 710; Mature: 710

Protein sequence:

>710_residues
MRLFNYILILEYSIILLFSIFVSGIVAQDNSDSMIVQKAETVRVIGKVSDSGSQNFRSNPSGFQSAIKLDETSERYTSLP
EVLEREAGLRVRSFGGLGSYSTLSIRGTNPNQSRIYLDGIPLNNSQGGEVNLADLPFDSLESVEVYRSGNPIGFSGSAIG
GSVNLVTRKDTGKPRTRVNLGGGSFNTGKASVSHTGTYNGIGASFLALGEKSDQNFSFKNDHGTVVLNTLDDTIDRRRNA
AFERAALFGTLKYQMGKTELKLLNDFNHRIHGLPGPGSNQTNRVHRKYDRYTGSFATDTKGLFVDFFRLETRSFYTAAKD
DLFDPGSEFSKGTPNSRAEIRQAGIQIMPTLYLTDYYQILRVFVSLERESFDRNRLTPSNVIGRVEPLKERTYSSFRLED
EVRLWNAKVLLVPSVTWDHYRDRFPSEEPWYRRQDLFASDSKKITFTNPKLGFVWKLFEREAWDVQFQANVSRQYRIPSF
LEMFGEQGSIIANPNLRPERSGNGDAGFVFKTNHSYLKTKTSVSYFSKDIKDMILFLPNSQFTLRPENVDSARIRGIEFS
HRVDWKYGIKFLFNYTYQDAINTSSSVYLRGKILPLRSRHEFASILSWKRKRLETGIELLYIGAVFRDRTNEYINYIPER
QIWNYFFTWILDSEPGESVKNSLGDLKESAPSREVLLTFETKNFTDRRVSDLIGYPLPGRSWYVTLSMRF

Sequences:

>Translated_710_residues
MRLFNYILILEYSIILLFSIFVSGIVAQDNSDSMIVQKAETVRVIGKVSDSGSQNFRSNPSGFQSAIKLDETSERYTSLP
EVLEREAGLRVRSFGGLGSYSTLSIRGTNPNQSRIYLDGIPLNNSQGGEVNLADLPFDSLESVEVYRSGNPIGFSGSAIG
GSVNLVTRKDTGKPRTRVNLGGGSFNTGKASVSHTGTYNGIGASFLALGEKSDQNFSFKNDHGTVVLNTLDDTIDRRRNA
AFERAALFGTLKYQMGKTELKLLNDFNHRIHGLPGPGSNQTNRVHRKYDRYTGSFATDTKGLFVDFFRLETRSFYTAAKD
DLFDPGSEFSKGTPNSRAEIRQAGIQIMPTLYLTDYYQILRVFVSLERESFDRNRLTPSNVIGRVEPLKERTYSSFRLED
EVRLWNAKVLLVPSVTWDHYRDRFPSEEPWYRRQDLFASDSKKITFTNPKLGFVWKLFEREAWDVQFQANVSRQYRIPSF
LEMFGEQGSIIANPNLRPERSGNGDAGFVFKTNHSYLKTKTSVSYFSKDIKDMILFLPNSQFTLRPENVDSARIRGIEFS
HRVDWKYGIKFLFNYTYQDAINTSSSVYLRGKILPLRSRHEFASILSWKRKRLETGIELLYIGAVFRDRTNEYINYIPER
QIWNYFFTWILDSEPGESVKNSLGDLKESAPSREVLLTFETKNFTDRRVSDLIGYPLPGRSWYVTLSMRF
>Mature_710_residues
MRLFNYILILEYSIILLFSIFVSGIVAQDNSDSMIVQKAETVRVIGKVSDSGSQNFRSNPSGFQSAIKLDETSERYTSLP
EVLEREAGLRVRSFGGLGSYSTLSIRGTNPNQSRIYLDGIPLNNSQGGEVNLADLPFDSLESVEVYRSGNPIGFSGSAIG
GSVNLVTRKDTGKPRTRVNLGGGSFNTGKASVSHTGTYNGIGASFLALGEKSDQNFSFKNDHGTVVLNTLDDTIDRRRNA
AFERAALFGTLKYQMGKTELKLLNDFNHRIHGLPGPGSNQTNRVHRKYDRYTGSFATDTKGLFVDFFRLETRSFYTAAKD
DLFDPGSEFSKGTPNSRAEIRQAGIQIMPTLYLTDYYQILRVFVSLERESFDRNRLTPSNVIGRVEPLKERTYSSFRLED
EVRLWNAKVLLVPSVTWDHYRDRFPSEEPWYRRQDLFASDSKKITFTNPKLGFVWKLFEREAWDVQFQANVSRQYRIPSF
LEMFGEQGSIIANPNLRPERSGNGDAGFVFKTNHSYLKTKTSVSYFSKDIKDMILFLPNSQFTLRPENVDSARIRGIEFS
HRVDWKYGIKFLFNYTYQDAINTSSSVYLRGKILPLRSRHEFASILSWKRKRLETGIELLYIGAVFRDRTNEYINYIPER
QIWNYFFTWILDSEPGESVKNSLGDLKESAPSREVLLTFETKNFTDRRVSDLIGYPLPGRSWYVTLSMRF

Specific function: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB [H]

COG id: COG4206

COG function: function code H; Outer membrane cobalamin receptor protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790405, Length=109, Percent_Identity=34.8623853211009, Blast_Score=63, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010101
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 81094; Mature: 81094

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLFNYILILEYSIILLFSIFVSGIVAQDNSDSMIVQKAETVRVIGKVSDSGSQNFRSNP
CCHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCEEEEECCEEEEEEECCCCCCCCCCCCC
SGFQSAIKLDETSERYTSLPEVLEREAGLRVRSFGGLGSYSTLSIRGTNPNQSRIYLDGI
HHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEECCCCCCCEEEEEEE
PLNNSQGGEVNLADLPFDSLESVEVYRSGNPIGFSGSAIGGSVNLVTRKDTGKPRTRVNL
ECCCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEE
GGGSFNTGKASVSHTGTYNGIGASFLALGEKSDQNFSFKNDHGTVVLNTLDDTIDRRRNA
CCCCCCCCCCEECCCCCCCCCCHHEEEECCCCCCCCEEECCCCEEEEECHHHHHHHHHHH
AFERAALFGTLKYQMGKTELKLLNDFNHRIHGLPGPGSNQTNRVHRKYDRYTGSFATDTK
HHHHHHHHHHHHHHCCCHHHHHHHHHCHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCC
GLFVDFFRLETRSFYTAAKDDLFDPGSEFSKGTPNSRAEIRQAGIQIMPTLYLTDYYQIL
CCEEEEEEHHHHHHHHHHCCCCCCCCCHHCCCCCCCHHHHHHCCCEEEEHHHHHHHHHHH
RVFVSLERESFDRNRLTPSNVIGRVEPLKERTYSSFRLEDEVRLWNAKVLLVPSVTWDHY
HHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHCCHHEEECCCEEEEEEEEEEEECCCHHHH
RDRFPSEEPWYRRQDLFASDSKKITFTNPKLGFVWKLFEREAWDVQFQANVSRQYRIPSF
HHCCCCCCCCHHHHHCCCCCCCEEEEECCCCCHHHEECCCCCCCEEEEECCCCCCCCHHH
LEMFGEQGSIIANPNLRPERSGNGDAGFVFKTNHSYLKTKTSVSYFSKDIKDMILFLPNS
HHHHCCCCCEEECCCCCCCCCCCCCEEEEEECCCCEEEEHHHHHHHHHHHHEEEEECCCC
QFTLRPENVDSARIRGIEFSHRVDWKYGIKFLFNYTYQDAINTSSSVYLRGKILPLRSRH
CEEECCCCCCCCEEECEEECEECCHHCCEEEEEEEEHHHHCCCCCEEEEEEEEEECCCHH
EFASILSWKRKRLETGIELLYIGAVFRDRTNEYINYIPERQIWNYFFTWILDSEPGESVK
HHHHHHHHHHHHHHCCCEEEEEEHHHHHCHHHHHHCCCCHHHHEEEEEEEECCCCCHHHH
NSLGDLKESAPSREVLLTFETKNFTDRRVSDLIGYPLPGRSWYVTLSMRF
HHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCEEEEEEEEEC
>Mature Secondary Structure
MRLFNYILILEYSIILLFSIFVSGIVAQDNSDSMIVQKAETVRVIGKVSDSGSQNFRSNP
CCHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCEEEEECCEEEEEEECCCCCCCCCCCCC
SGFQSAIKLDETSERYTSLPEVLEREAGLRVRSFGGLGSYSTLSIRGTNPNQSRIYLDGI
HHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEECCCCCCCEEEEEEE
PLNNSQGGEVNLADLPFDSLESVEVYRSGNPIGFSGSAIGGSVNLVTRKDTGKPRTRVNL
ECCCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEE
GGGSFNTGKASVSHTGTYNGIGASFLALGEKSDQNFSFKNDHGTVVLNTLDDTIDRRRNA
CCCCCCCCCCEECCCCCCCCCCHHEEEECCCCCCCCEEECCCCEEEEECHHHHHHHHHHH
AFERAALFGTLKYQMGKTELKLLNDFNHRIHGLPGPGSNQTNRVHRKYDRYTGSFATDTK
HHHHHHHHHHHHHHCCCHHHHHHHHHCHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCC
GLFVDFFRLETRSFYTAAKDDLFDPGSEFSKGTPNSRAEIRQAGIQIMPTLYLTDYYQIL
CCEEEEEEHHHHHHHHHHCCCCCCCCCHHCCCCCCCHHHHHHCCCEEEEHHHHHHHHHHH
RVFVSLERESFDRNRLTPSNVIGRVEPLKERTYSSFRLEDEVRLWNAKVLLVPSVTWDHY
HHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHCCHHEEECCCEEEEEEEEEEEECCCHHHH
RDRFPSEEPWYRRQDLFASDSKKITFTNPKLGFVWKLFEREAWDVQFQANVSRQYRIPSF
HHCCCCCCCCHHHHHCCCCCCCEEEEECCCCCHHHEECCCCCCCEEEEECCCCCCCCHHH
LEMFGEQGSIIANPNLRPERSGNGDAGFVFKTNHSYLKTKTSVSYFSKDIKDMILFLPNS
HHHHCCCCCEEECCCCCCCCCCCCCEEEEEECCCCEEEEHHHHHHHHHHHHEEEEECCCC
QFTLRPENVDSARIRGIEFSHRVDWKYGIKFLFNYTYQDAINTSSSVYLRGKILPLRSRH
CEEECCCCCCCCEEECEEECEECCHHCCEEEEEEEEHHHHCCCCCEEEEEEEEEECCCHH
EFASILSWKRKRLETGIELLYIGAVFRDRTNEYINYIPERQIWNYFFTWILDSEPGESVK
HHHHHHHHHHHHHHCCCEEEEEEHHHHHCHHHHHHCCCCHHHHEEEEEEEECCCCCHHHH
NSLGDLKESAPSREVLLTFETKNFTDRRVSDLIGYPLPGRSWYVTLSMRF
HHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA