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The map label for this gene is sucD [H]

Identifier: 116327601

GI number: 116327601

Start: 964470

End: 965345

Strand: Reverse

Name: sucD [H]

Synonym: LBL_0833

Alternate gene names: 116327601

Gene position: 965345-964470 (Counterclockwise)

Preceding gene: 116327602

Following gene: 116327600

Centisome position: 26.71

GC content: 50.46

Gene sequence:

>876_bases
ATGGCAGTATTAGTAGACGAAAATACAAAAGTCGTAGTCCAAGGGATCACCGGTAAGGAAGGTTCTTTCCACGCGACACA
AATGCTCGCTTACGGCACAAAGGTTGTAGCCGGAGTGACTCCCGGAAAAGGCGGAAGCAAATGGGAAGATAAGGTTCCCG
TTTTCAACACGATCAAGGATTCCGTTAAAAACGAAGGCGTAAACGCCGCAGTCATCTTTGTTCCTCCCGCTTTCGCGGCG
GATGCGATCATCGAAGGAATTCTCGCGGAACTTCCTCTCGTGATCTGTATCACGGAAGGAATTCCTACACACGATATGCT
GAAGGTTTACAGCGTTCTTAGAAATTCTAAAACGAGACTGGTGGGACCGAACTGTCCCGGAGTGATCACTCCCCGCGCAA
AACAAAAACTCGGAATTATGCCCGGTTTTATCCACAGTCCTGGTTCGGTTGGAATCGTTTCCCGTTCCGGAACCTTGACG
TACGAATCGGTGGCTCAGATCACAAAACAAGGTCTGGGACAATCCACTTGTATCGGAATCGGAGGAGACCCCGTTCCCGG
TATGAATCACACCGAAGCCATCCAATTGTTAAACGAAGACCCGGAAACCAAGGGAATCGTGATGATCGGAGAAATCGGAG
GAACTTCGGAAGAAGAAGCCGCCGAATACATCAAGAATCACGTAAAAAAACCGGTAGTCGGGTTTATCGCCGGTCAAACC
GCGCCTCCCGGTAAAAGAATGGGACACGCGGGAGCGATCATCAGCGGCGGCCTCGGAACGGCGACCTCCAAAATGAAAGC
GATGCAGGAAGCGGGAATTCAAGTTTGCCAATCCATCGCGGAAGTCGGAGAAAAAATGAAGAAGGCTCTGGGGTAA

Upstream 100 bases:

>100_bases
AGAAGTCCTCAACAAAAGCGGACTGAAAATTACCGGAGTCGACGACCTCCGCGAAGCGGCAAGCACCATTGCCAAACTGA
TCAAGTAAGAGAGAACACAC

Downstream 100 bases:

>100_bases
TATTACAATGTCGTAAATGTAAGACACGATTTTCAGAAGACGAAACAAAATGAATTTGTAAGCGTTAAAGTTGATGAAAG
AACATCGGCCCTTTAAATCG

Product: succinyl-CoA synthetase, alpha subunit

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha; Vegetative protein 239; VEG239 [H]

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MAVLVDENTKVVVQGITGKEGSFHATQMLAYGTKVVAGVTPGKGGSKWEDKVPVFNTIKDSVKNEGVNAAVIFVPPAFAA
DAIIEGILAELPLVICITEGIPTHDMLKVYSVLRNSKTRLVGPNCPGVITPRAKQKLGIMPGFIHSPGSVGIVSRSGTLT
YESVAQITKQGLGQSTCIGIGGDPVPGMNHTEAIQLLNEDPETKGIVMIGEIGGTSEEEAAEYIKNHVKKPVVGFIAGQT
APPGKRMGHAGAIISGGLGTATSKMKAMQEAGIQVCQSIAEVGEKMKKALG

Sequences:

>Translated_291_residues
MAVLVDENTKVVVQGITGKEGSFHATQMLAYGTKVVAGVTPGKGGSKWEDKVPVFNTIKDSVKNEGVNAAVIFVPPAFAA
DAIIEGILAELPLVICITEGIPTHDMLKVYSVLRNSKTRLVGPNCPGVITPRAKQKLGIMPGFIHSPGSVGIVSRSGTLT
YESVAQITKQGLGQSTCIGIGGDPVPGMNHTEAIQLLNEDPETKGIVMIGEIGGTSEEEAAEYIKNHVKKPVVGFIAGQT
APPGKRMGHAGAIISGGLGTATSKMKAMQEAGIQVCQSIAEVGEKMKKALG
>Mature_290_residues
AVLVDENTKVVVQGITGKEGSFHATQMLAYGTKVVAGVTPGKGGSKWEDKVPVFNTIKDSVKNEGVNAAVIFVPPAFAAD
AIIEGILAELPLVICITEGIPTHDMLKVYSVLRNSKTRLVGPNCPGVITPRAKQKLGIMPGFIHSPGSVGIVSRSGTLTY
ESVAQITKQGLGQSTCIGIGGDPVPGMNHTEAIQLLNEDPETKGIVMIGEIGGTSEEEAAEYIKNHVKKPVVGFIAGQTA
PPGKRMGHAGAIISGGLGTATSKMKAMQEAGIQVCQSIAEVGEKMKKALG

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=293, Percent_Identity=56.9965870307167, Blast_Score=274, Evalue=8e-74,
Organism=Homo sapiens, GI38569421, Length=305, Percent_Identity=30.1639344262295, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI38569423, Length=305, Percent_Identity=30.1639344262295, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI1786949, Length=290, Percent_Identity=58.9655172413793, Blast_Score=349, Evalue=1e-97,
Organism=Caenorhabditis elegans, GI17550194, Length=291, Percent_Identity=56.3573883161512, Blast_Score=304, Evalue=3e-83,
Organism=Caenorhabditis elegans, GI17553126, Length=293, Percent_Identity=52.5597269624573, Blast_Score=280, Evalue=7e-76,
Organism=Caenorhabditis elegans, GI17557344, Length=309, Percent_Identity=26.8608414239482, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17551266, Length=309, Percent_Identity=26.8608414239482, Blast_Score=90, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6324716, Length=292, Percent_Identity=49.3150684931507, Blast_Score=270, Evalue=2e-73,
Organism=Drosophila melanogaster, GI21356559, Length=287, Percent_Identity=51.9163763066202, Blast_Score=290, Evalue=6e-79,
Organism=Drosophila melanogaster, GI28574296, Length=291, Percent_Identity=52.5773195876289, Blast_Score=270, Evalue=7e-73,
Organism=Drosophila melanogaster, GI281363477, Length=277, Percent_Identity=31.7689530685921, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI281363475, Length=277, Percent_Identity=31.7689530685921, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI281363473, Length=277, Percent_Identity=31.7689530685921, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30208; Mature: 30076

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVLVDENTKVVVQGITGKEGSFHATQMLAYGTKVVAGVTPGKGGSKWEDKVPVFNTIKD
CEEEEECCCEEEEEECCCCCCCHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCHHHHHHH
SVKNEGVNAAVIFVPPAFAADAIIEGILAELPLVICITEGIPTHDMLKVYSVLRNSKTRL
HHHCCCCCEEEEEECCHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHCCCCEE
VGPNCPGVITPRAKQKLGIMPGFIHSPGSVGIVSRSGTLTYESVAQITKQGLGQSTCIGI
ECCCCCCCCCCCHHHHHCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEEC
GGDPVPGMNHTEAIQLLNEDPETKGIVMIGEIGGTSEEEAAEYIKNHVKKPVVGFIAGQT
CCCCCCCCCHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCC
APPGKRMGHAGAIISGGLGTATSKMKAMQEAGIQVCQSIAEVGEKMKKALG
CCCCHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AVLVDENTKVVVQGITGKEGSFHATQMLAYGTKVVAGVTPGKGGSKWEDKVPVFNTIKD
EEEEECCCEEEEEECCCCCCCHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCHHHHHHH
SVKNEGVNAAVIFVPPAFAADAIIEGILAELPLVICITEGIPTHDMLKVYSVLRNSKTRL
HHHCCCCCEEEEEECCHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHCCCCEE
VGPNCPGVITPRAKQKLGIMPGFIHSPGSVGIVSRSGTLTYESVAQITKQGLGQSTCIGI
ECCCCCCCCCCCHHHHHCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEEC
GGDPVPGMNHTEAIQLLNEDPETKGIVMIGEIGGTSEEEAAEYIKNHVKKPVVGFIAGQT
CCCCCCCCCHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCC
APPGKRMGHAGAIISGGLGTATSKMKAMQEAGIQVCQSIAEVGEKMKKALG
CCCCHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9298659 [H]