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The map label for this gene is trpS [H]

Identifier: 116327459

GI number: 116327459

Start: 756885

End: 757853

Strand: Reverse

Name: trpS [H]

Synonym: LBL_0676

Alternate gene names: 116327459

Gene position: 757853-756885 (Counterclockwise)

Preceding gene: 116327460

Following gene: 116327457

Centisome position: 20.97

GC content: 42.52

Gene sequence:

>969_bases
ATGAGGATTCTCACAGGAGTCCAACCCTCTGGTAAGCTTCATTTAGGAAATTTTTTCTCCGTCATTCGAAAGCTCAAAGA
ATATCAGGATTCGGCGGACCTATTTTGTTTTATCGCAGATCTGCATTCTTTAACTACGTTCTCTTCGAAAGAAAAACAAA
AAGAAAACACATTCAACGCAGTCTGCGATTTTTTAGCTCTGGGAATCGACCCGGATCGGTGTACGTTTTGGCTACAATCC
GGAGTTCCGGAAGTCACCGAACTAACCTGGTATCTGAGTCATTCGATCACCGTCAACCAGTTGAACTTGGCGCATTCTTA
CAAAGATAAGGTTGCAAAAGGTTTTAATCCCGGAGGCGGGCTTTTTTTCTATCCGGTTTTGATGGCGGCGGATATTCTCG
GCTTCGACAGCGACCAGGTTCCTGTCGGTAAAGACCAAAAGCAACATTTGGAATTTGCCAGAGACATCGCTTCGAATTTC
AATCGGGAAATCGGTCCCGTTTTTAAAGTCCCCGAACCTGAAATCGACGAAACAACGGCTTTGGTTCCCGGTACGGACGG
ACAGAAAATGTCCAAGTCTTACGGGAACACGATCAACTTTTTCGATTCCGAAAAAGAACTTAAGAAATCCATAATGTCTA
TCACAACCGATTCCGCGGGAATCGACGAAGTCAAAGATCCCTCCAAAAGTAATATTTATGCGATTCATTCTTTGTTTTTA
GATGAAAAAGGAAGAGAAGCCCTAAAACAGAAGTTTTTAATCCCCGGAACCGGATACGGAGAACTTAAAAAACAACTTTT
ACAGGATACCTTGGATTATTTTGCCCCTTTTCGCCAGGAACGGGAAAAAATCGGGAAAGACAAATCTTTTGTGGAAGCGG
CTCTTAAAAAAGGACAAGAAAAAGCCAGAAATACAATCACAAACGTCCTTGATCGAACCCGCAAAGAATTAGGGATTTAT
CGGTTTTAA

Upstream 100 bases:

>100_bases
TGACCTTACATAAAAAACTAGACGCAGAACTTGGATCTCTAACGAAAGAATACGAGAGACTTTCCGGTAAACCTTACGAG
ACAAAGCGAATGGAGGAAAC

Downstream 100 bases:

>100_bases
AATCCAGAATATTCTATTTTTATTATGTAATTAAATCGCTCCATCTTTTCCGCTTTTCCCTTCGAACCGATTCGATCCCG
TGCTGTCTTTCTTTATCTCG

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MRILTGVQPSGKLHLGNFFSVIRKLKEYQDSADLFCFIADLHSLTTFSSKEKQKENTFNAVCDFLALGIDPDRCTFWLQS
GVPEVTELTWYLSHSITVNQLNLAHSYKDKVAKGFNPGGGLFFYPVLMAADILGFDSDQVPVGKDQKQHLEFARDIASNF
NREIGPVFKVPEPEIDETTALVPGTDGQKMSKSYGNTINFFDSEKELKKSIMSITTDSAGIDEVKDPSKSNIYAIHSLFL
DEKGREALKQKFLIPGTGYGELKKQLLQDTLDYFAPFRQEREKIGKDKSFVEAALKKGQEKARNTITNVLDRTRKELGIY
RF

Sequences:

>Translated_322_residues
MRILTGVQPSGKLHLGNFFSVIRKLKEYQDSADLFCFIADLHSLTTFSSKEKQKENTFNAVCDFLALGIDPDRCTFWLQS
GVPEVTELTWYLSHSITVNQLNLAHSYKDKVAKGFNPGGGLFFYPVLMAADILGFDSDQVPVGKDQKQHLEFARDIASNF
NREIGPVFKVPEPEIDETTALVPGTDGQKMSKSYGNTINFFDSEKELKKSIMSITTDSAGIDEVKDPSKSNIYAIHSLFL
DEKGREALKQKFLIPGTGYGELKKQLLQDTLDYFAPFRQEREKIGKDKSFVEAALKKGQEKARNTITNVLDRTRKELGIY
RF
>Mature_322_residues
MRILTGVQPSGKLHLGNFFSVIRKLKEYQDSADLFCFIADLHSLTTFSSKEKQKENTFNAVCDFLALGIDPDRCTFWLQS
GVPEVTELTWYLSHSITVNQLNLAHSYKDKVAKGFNPGGGLFFYPVLMAADILGFDSDQVPVGKDQKQHLEFARDIASNF
NREIGPVFKVPEPEIDETTALVPGTDGQKMSKSYGNTINFFDSEKELKKSIMSITTDSAGIDEVKDPSKSNIYAIHSLFL
DEKGREALKQKFLIPGTGYGELKKQLLQDTLDYFAPFRQEREKIGKDKSFVEAALKKGQEKARNTITNVLDRTRKELGIY
RF

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=326, Percent_Identity=32.8220858895706, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI41352700, Length=173, Percent_Identity=40.4624277456647, Blast_Score=135, Evalue=4e-32,
Organism=Escherichia coli, GI1789786, Length=327, Percent_Identity=34.5565749235474, Blast_Score=176, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI71982800, Length=334, Percent_Identity=30.5389221556886, Blast_Score=128, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI71982793, Length=333, Percent_Identity=29.7297297297297, Blast_Score=127, Evalue=9e-30,
Organism=Saccharomyces cerevisiae, GI6320474, Length=347, Percent_Identity=29.3948126801153, Blast_Score=122, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24666151, Length=329, Percent_Identity=30.6990881458967, Blast_Score=153, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 36320; Mature: 36320

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILTGVQPSGKLHLGNFFSVIRKLKEYQDSADLFCFIADLHSLTTFSSKEKQKENTFNA
CCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VCDFLALGIDPDRCTFWLQSGVPEVTELTWYLSHSITVNQLNLAHSYKDKVAKGFNPGGG
HHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHCCEEEEHHHHHHHHHHHHHCCCCCCCC
LFFYPVLMAADILGFDSDQVPVGKDQKQHLEFARDIASNFNREIGPVFKVPEPEIDETTA
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEE
LVPGTDGQKMSKSYGNTINFFDSEKELKKSIMSITTDSAGIDEVKDPSKSNIYAIHSLFL
ECCCCCCHHHHHHHCCEECCCCCHHHHHHHHHHHCCCCCCCCHHCCCCCCCHHHHHHHHH
DEKGREALKQKFLIPGTGYGELKKQLLQDTLDYFAPFRQEREKIGKDKSFVEAALKKGQE
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
KARNTITNVLDRTRKELGIYRF
HHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRILTGVQPSGKLHLGNFFSVIRKLKEYQDSADLFCFIADLHSLTTFSSKEKQKENTFNA
CCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VCDFLALGIDPDRCTFWLQSGVPEVTELTWYLSHSITVNQLNLAHSYKDKVAKGFNPGGG
HHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHCCEEEEHHHHHHHHHHHHHCCCCCCCC
LFFYPVLMAADILGFDSDQVPVGKDQKQHLEFARDIASNFNREIGPVFKVPEPEIDETTA
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEE
LVPGTDGQKMSKSYGNTINFFDSEKELKKSIMSITTDSAGIDEVKDPSKSNIYAIHSLFL
ECCCCCCHHHHHHHCCEECCCCCHHHHHHHHHHHCCCCCCCCHHCCCCCCCHHHHHHHHH
DEKGREALKQKFLIPGTGYGELKKQLLQDTLDYFAPFRQEREKIGKDKSFVEAALKKGQE
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
KARNTITNVLDRTRKELGIYRF
HHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]