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The map label for this gene is obgE

Identifier: 116327412

GI number: 116327412

Start: 694773

End: 695870

Strand: Reverse

Name: obgE

Synonym: LBL_0621

Alternate gene names: 116327412

Gene position: 695870-694773 (Counterclockwise)

Preceding gene: 116327413

Following gene: 116327411

Centisome position: 19.25

GC content: 44.81

Gene sequence:

>1098_bases
ATGGAATCCTTTGTAGACGAAGTAGCCATCGAAGTGTTTGCCGGTCACGGCGGAGCCGGTTCCGTCCACTTCCGGAGGGA
GAAATACGTCGAGTTTGGCGGTCCCGACGGAGGGGATGGAGGAACCGGAGGAAATGTTATCATTCGTCCTAATCTTTCCA
TGTATACCCTTGACAAATATCTTTCTAAAAGGAAGTTCAAAGCGGAAGCGGGTTTTCCCGGTGTCGGAGACAATTGCTCG
GGCAAAAAGGGAGAAGACCTGATTCTGTTCGTTCCTCTGGGAACTCAAATTTACGACGAGGAAACGGGAGACTTGCTCTT
CGATTTCGTTACCGATACGCAGGAATTCGTAGTCGCTCGAGGCGGTCGAGGAGGCAAAGGGAACACTCATTTTAAATCTT
CCACAAATCAAACTCCCCGCTTCGCTCAACCCGGAGAAGAAGGAGAATATAAATTTTTACGCCTTTCTCTGAAACTTTTA
GCTGACGTCGGAATCGTAGGTCTTCCAAACGCGGGTAAATCCACTTTGATCTCGAAGATCACGGATGCCCATCCTAAAAT
AGCGGGTTATGCGTTCACGACTCTTTCCCCGAATCTCGGAGTTGTTAAGCGAAGAGGAGACATCTTTCGTTTTACGATCG
CGGACATCCCCGGCATTATCGAAGGCGCGAGTATGGGAATCGGACTCGGTCTTTCTTTTTTACGCCACATAGAACGAGTC
AAAGGAATTTTATATCTTTTCGACGCTTCTTCCCTGGATATTGAGGAAGATTTGAAGATGCTTCGGAACGAACTTTTCAC
ATACAATCCGGAGTTGCTCAATCGACCTTACCTTATCGTACTAAACAAGATCGATATTTGGGATGATCCCGAATTTACGA
AGGATATAATCTCCAAAATTATTCATCTCGGCAAAGTGATCGCCATCTCCGCGGATAAAGAGACGAATCTGGAAAAACTT
TTGGAAGCGATGGATGAGGCTTTTTTTAAGGATGAAATCGAAAAGGTCCTTAAATCAACCAAAGAATTAAAATCTGTCTC
TTTGAATGAATCCGATATTTTAGGTTCTTTCGAAAACTCAAGGGAAATTAAAGAATGA

Upstream 100 bases:

>100_bases
TCTCAAACCGGATGAACCGCAGTCTCCTGCCCGTTTCGGGTCCGGACTCTGCGGTTTTTTGTTTTTAGAATGATTTAAAA
ATTTAGAATATTCAAACATC

Downstream 100 bases:

>100_bases
AATCCTCCGTTTCAGAATATTTTTTTCTTTGGAGGTTATTCCAAGGCCTCAAAATCTGGAATCCACACTTCGAACGGCTA
GTAACGGGTATTTAAGGGCT

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MESFVDEVAIEVFAGHGGAGSVHFRREKYVEFGGPDGGDGGTGGNVIIRPNLSMYTLDKYLSKRKFKAEAGFPGVGDNCS
GKKGEDLILFVPLGTQIYDEETGDLLFDFVTDTQEFVVARGGRGGKGNTHFKSSTNQTPRFAQPGEEGEYKFLRLSLKLL
ADVGIVGLPNAGKSTLISKITDAHPKIAGYAFTTLSPNLGVVKRRGDIFRFTIADIPGIIEGASMGIGLGLSFLRHIERV
KGILYLFDASSLDIEEDLKMLRNELFTYNPELLNRPYLIVLNKIDIWDDPEFTKDIISKIIHLGKVIAISADKETNLEKL
LEAMDEAFFKDEIEKVLKSTKELKSVSLNESDILGSFENSREIKE

Sequences:

>Translated_365_residues
MESFVDEVAIEVFAGHGGAGSVHFRREKYVEFGGPDGGDGGTGGNVIIRPNLSMYTLDKYLSKRKFKAEAGFPGVGDNCS
GKKGEDLILFVPLGTQIYDEETGDLLFDFVTDTQEFVVARGGRGGKGNTHFKSSTNQTPRFAQPGEEGEYKFLRLSLKLL
ADVGIVGLPNAGKSTLISKITDAHPKIAGYAFTTLSPNLGVVKRRGDIFRFTIADIPGIIEGASMGIGLGLSFLRHIERV
KGILYLFDASSLDIEEDLKMLRNELFTYNPELLNRPYLIVLNKIDIWDDPEFTKDIISKIIHLGKVIAISADKETNLEKL
LEAMDEAFFKDEIEKVLKSTKELKSVSLNESDILGSFENSREIKE
>Mature_365_residues
MESFVDEVAIEVFAGHGGAGSVHFRREKYVEFGGPDGGDGGTGGNVIIRPNLSMYTLDKYLSKRKFKAEAGFPGVGDNCS
GKKGEDLILFVPLGTQIYDEETGDLLFDFVTDTQEFVVARGGRGGKGNTHFKSSTNQTPRFAQPGEEGEYKFLRLSLKLL
ADVGIVGLPNAGKSTLISKITDAHPKIAGYAFTTLSPNLGVVKRRGDIFRFTIADIPGIIEGASMGIGLGLSFLRHIERV
KGILYLFDASSLDIEEDLKMLRNELFTYNPELLNRPYLIVLNKIDIWDDPEFTKDIISKIIHLGKVIAISADKETNLEKL
LEAMDEAFFKDEIEKVLKSTKELKSVSLNESDILGSFENSREIKE

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=319, Percent_Identity=42.6332288401254, Blast_Score=188, Evalue=6e-48,
Organism=Homo sapiens, GI111955139, Length=264, Percent_Identity=34.469696969697, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI111955063, Length=167, Percent_Identity=38.3233532934132, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI58761500, Length=149, Percent_Identity=30.2013422818792, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1789574, Length=291, Percent_Identity=47.766323024055, Blast_Score=227, Evalue=9e-61,
Organism=Caenorhabditis elegans, GI17508313, Length=329, Percent_Identity=39.8176291793313, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17552324, Length=310, Percent_Identity=30.3225806451613, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI71981008, Length=116, Percent_Identity=39.6551724137931, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17509631, Length=139, Percent_Identity=30.2158273381295, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321962, Length=159, Percent_Identity=46.5408805031447, Blast_Score=143, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6321612, Length=90, Percent_Identity=42.2222222222222, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20129375, Length=327, Percent_Identity=37.6146788990826, Blast_Score=160, Evalue=9e-40,
Organism=Drosophila melanogaster, GI24585318, Length=292, Percent_Identity=32.8767123287671, Blast_Score=144, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_LEPBJ (Q04Q90)

Other databases:

- EMBL:   CP000350
- RefSeq:   YP_801688.1
- ProteinModelPortal:   Q04Q90
- SMR:   Q04Q90
- STRING:   Q04Q90
- GeneID:   4412102
- GenomeReviews:   CP000350_GR
- KEGG:   lbj:LBJ_2492
- eggNOG:   COG0536
- HOGENOM:   HBG716038
- OMA:   RNRTGAK
- PhylomeDB:   Q04Q90
- ProtClustDB:   PRK12299
- BioCyc:   LBOR355277:LBJ_2492-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 40241; Mature: 40241

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESFVDEVAIEVFAGHGGAGSVHFRREKYVEFGGPDGGDGGTGGNVIIRPNLSMYTLDKY
CCHHHHHHHHHHEECCCCCCCEEEEHHHHEECCCCCCCCCCCCCEEEECCCCCHHHHHHH
LSKRKFKAEAGFPGVGDNCSGKKGEDLILFVPLGTQIYDEETGDLLFDFVTDTQEFVVAR
HHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCEEECCCCCCEEEHHHHCCHHEEEEC
GGRGGKGNTHFKSSTNQTPRFAQPGEEGEYKFLRLSLKLLADVGIVGLPNAGKSTLISKI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCEEECCCCCHHHHHHHH
TDAHPKIAGYAFTTLSPNLGVVKRRGDIFRFTIADIPGIIEGASMGIGLGLSFLRHIERV
HHCCCCCCEEEEEECCCCCCEEEECCCEEEEECCCCCCHHCCCCCCHHHHHHHHHHHHHH
KGILYLFDASSLDIEEDLKMLRNELFTYNPELLNRPYLIVLNKIDIWDDPEFTKDIISKI
CCEEEEEECCCCCHHHHHHHHHHHHCCCCHHHHCCCEEEEEEEECCCCCCHHHHHHHHHH
IHLGKVIAISADKETNLEKLLEAMDEAFFKDEIEKVLKSTKELKSVSLNESDILGSFENS
HHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCC
REIKE
CCCCC
>Mature Secondary Structure
MESFVDEVAIEVFAGHGGAGSVHFRREKYVEFGGPDGGDGGTGGNVIIRPNLSMYTLDKY
CCHHHHHHHHHHEECCCCCCCEEEEHHHHEECCCCCCCCCCCCCEEEECCCCCHHHHHHH
LSKRKFKAEAGFPGVGDNCSGKKGEDLILFVPLGTQIYDEETGDLLFDFVTDTQEFVVAR
HHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCEEECCCCCCEEEHHHHCCHHEEEEC
GGRGGKGNTHFKSSTNQTPRFAQPGEEGEYKFLRLSLKLLADVGIVGLPNAGKSTLISKI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCEEECCCCCHHHHHHHH
TDAHPKIAGYAFTTLSPNLGVVKRRGDIFRFTIADIPGIIEGASMGIGLGLSFLRHIERV
HHCCCCCCEEEEEECCCCCCEEEECCCEEEEECCCCCCHHCCCCCCHHHHHHHHHHHHHH
KGILYLFDASSLDIEEDLKMLRNELFTYNPELLNRPYLIVLNKIDIWDDPEFTKDIISKI
CCEEEEEECCCCCHHHHHHHHHHHHCCCCHHHHCCCEEEEEEEECCCCCCHHHHHHHHHH
IHLGKVIAISADKETNLEKLLEAMDEAFFKDEIEKVLKSTKELKSVSLNESDILGSFENS
HHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCC
REIKE
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA