Click here to switch to the map view.

The map label for this gene is lepB-1 [H]

Identifier: 116327362

GI number: 116327362

Start: 617561

End: 618157

Strand: Reverse

Name: lepB-1 [H]

Synonym: LBL_0558

Alternate gene names: 116327362

Gene position: 618157-617561 (Counterclockwise)

Preceding gene: 116327363

Following gene: 116327359

Centisome position: 17.1

GC content: 39.7

Gene sequence:

>597_bases
ATGTCTTACGTTCTTATGAAAAGTTTCGGAACGAAGGAAAAAATGAGAAAATATTTACGCATTCTTTTTCCTGTATTTCT
TTCTTTGTTCACGATTCTTTTGATACGGATCTTTTTATTTCAAATTTATTTCATTTCAGGTTATTCCATGGCCCCTTCTT
ATAAGGAAGGAGATTTAATCTTAGTCACAAAGTTAGGTTTTCCTGCCCGCATCGGGAATTGGGAAATTTCTTTTGTTGAG
AGCGATGTGAATCGTTTCGACGTTCTCGTCTTAGACGGACTCGGGGAAGAATTGAGTCTCAAAAGAGTCGTAGGACTTCC
GGGAGATTATTTTAGTTTTGAAAACGATAGAATCCTAATCAACGACGGACCTCTCCAAGAAACCTTTTTAAAGCCGGGCT
TTAAAACCATCGCCCCTTCTCTTTCCATGGTTCCGATGACCGCAGTCAAAGGAAACGTTCCAATCGGAGACACGGGTAGA
ATTCCTCCCGGCTATTTTTTAGTGTTAGGCGATAATCGAGAGAACTCGACAGATTCAAGGAATTACGGTCTGGTTCCGTT
TCACAAACTGAGAGGGAAAGTTTGGTTTTTTTTATAA

Upstream 100 bases:

>100_bases
TTACCGAATTTGTAGACCCTTAGGATCTTTTACGTTTAACGTAGATACAATCTTTCTAAGCGTATTTTTCGATTTGCCGT
CCTAAAGAAGATTGTGGACA

Downstream 100 bases:

>100_bases
ACTCTCCAAATTTCGTTTTTTCCTTTTGAACGGAGTCGCCATTGAAAAGAAAAACTAATGTTGTTGAAAAATTATCATAT
TCATTTTTACGAATATATCT

Product: Signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MSYVLMKSFGTKEKMRKYLRILFPVFLSLFTILLIRIFLFQIYFISGYSMAPSYKEGDLILVTKLGFPARIGNWEISFVE
SDVNRFDVLVLDGLGEELSLKRVVGLPGDYFSFENDRILINDGPLQETFLKPGFKTIAPSLSMVPMTAVKGNVPIGDTGR
IPPGYFLVLGDNRENSTDSRNYGLVPFHKLRGKVWFFL

Sequences:

>Translated_198_residues
MSYVLMKSFGTKEKMRKYLRILFPVFLSLFTILLIRIFLFQIYFISGYSMAPSYKEGDLILVTKLGFPARIGNWEISFVE
SDVNRFDVLVLDGLGEELSLKRVVGLPGDYFSFENDRILINDGPLQETFLKPGFKTIAPSLSMVPMTAVKGNVPIGDTGR
IPPGYFLVLGDNRENSTDSRNYGLVPFHKLRGKVWFFL
>Mature_197_residues
SYVLMKSFGTKEKMRKYLRILFPVFLSLFTILLIRIFLFQIYFISGYSMAPSYKEGDLILVTKLGFPARIGNWEISFVES
DVNRFDVLVLDGLGEELSLKRVVGLPGDYFSFENDRILINDGPLQETFLKPGFKTIAPSLSMVPMTAVKGNVPIGDTGRI
PPGYFLVLGDNRENSTDSRNYGLVPFHKLRGKVWFFL

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 22526; Mature: 22395

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYVLMKSFGTKEKMRKYLRILFPVFLSLFTILLIRIFLFQIYFISGYSMAPSYKEGDLI
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEE
LVTKLGFPARIGNWEISFVESDVNRFDVLVLDGLGEELSLKRVVGLPGDYFSFENDRILI
EEEECCCCEEECCEEEEEEECCCCEEEEEEEECCCCCCCHHHHCCCCCCCCCCCCCEEEE
NDGPLQETFLKPGFKTIAPSLSMVPMTAVKGNVPIGDTGRIPPGYFLVLGDNRENSTDSR
ECCCCHHHHHCCCHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCC
NYGLVPFHKLRGKVWFFL
CCCCCCHHHHCCEEEEEC
>Mature Secondary Structure 
SYVLMKSFGTKEKMRKYLRILFPVFLSLFTILLIRIFLFQIYFISGYSMAPSYKEGDLI
CEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEE
LVTKLGFPARIGNWEISFVESDVNRFDVLVLDGLGEELSLKRVVGLPGDYFSFENDRILI
EEEECCCCEEECCEEEEEEECCCCEEEEEEEECCCCCCCHHHHCCCCCCCCCCCCCEEEE
NDGPLQETFLKPGFKTIAPSLSMVPMTAVKGNVPIGDTGRIPPGYFLVLGDNRENSTDSR
ECCCCHHHHHCCCHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCC
NYGLVPFHKLRGKVWFFL
CCCCCCHHHHCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8801417 [H]