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The map label for this gene is tktN [C]

Identifier: 116327303

GI number: 116327303

Start: 542904

End: 543728

Strand: Reverse

Name: tktN [C]

Synonym: LBL_0493

Alternate gene names: 116327303

Gene position: 543728-542904 (Counterclockwise)

Preceding gene: 116327304

Following gene: 116327302

Centisome position: 15.04

GC content: 44.85

Gene sequence:

>825_bases
ATGAACGATATCAAAGAACTCAAAAATTTTGCAAACGAGCTCAGAAAGAGCGTGATCCGAATGGTGACTGCCGCAAATTC
CGGACATCCGGGAGGACCTTTAGGTCTCGCGGATATCTATGCGGTGCTATATAAGAAAATTCTAAATCATAAACCCTCCA
ATCCGGATTGGGAAGGAAGGGATCGCTTAGTTCTTTCCAACGGCCACGTATGTGCGATTCGTTACGCCGCGATGGCTCAT
TCCGGTTATTTTCCCGTGGAAGACCTACTCACTTTCCGCAAATTAGGAAGCAAACTGCAAGGGCATCCTTCCACCCGTTA
TATGAACGGAATTGAAAGTTCTTCCGGTTCTTTAGGCCAAGGACTTTCCGTCTCTGTGGGACTCGCACTCGGCGCAAGAT
TCAAAAAACAAAGTCACAAAATTTATACGTGTATCTCCGACGGAGAATGCGGCGAAGGAATGACTTGGGAAGCCGCTCAA
TCCGCCACACACTATAAACTGGACAACTTGATCGCTTTTATGGACAAAAATGGAATTCAAATCGACGGCTTTACGAAAGA
CGTTATGAATCTAGAACCTCTGAGTAAAAAATTTCTTTCTTTCGGTTGGAACGTTTTGGAAGCGGACGGTCACGATATCG
AACAGATCATCTCTGCATTCGAAAAAGCTAAACTTCACAAAGGTTCTCCGACAATCATTCTGTTCGACACCATACTCGGC
AAAGGTGTCTCTTTTATGGAAAATAATCCGGGATGGCACGGAACTCCTCCAAAACCGGAGGAAGAAAAAAAAGCTCTCGA
AGAATTATCGGCACTTTCCGTTTAG

Upstream 100 bases:

>100_bases
ACTGCGATTTTCCTTTCCGGCTTGGTTTTGTTTCGCTCCACAAACTGAGAGCATCTCATTTCGGAGTTGGAAATCGCTAT
CGCATTCGCTTAGGAAGAAT

Downstream 100 bases:

>100_bases
ACGAACAACTCCCTACATTTCTCTTGTGGGAGTCTTTCCTTTTTTTAATTCTTTCATTTTCTTTATTTTTCAATTTCCAA
CTCTTTCTTTGTTCGCTTGT

Product: transketolase, N-terminal subunit

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MNDIKELKNFANELRKSVIRMVTAANSGHPGGPLGLADIYAVLYKKILNHKPSNPDWEGRDRLVLSNGHVCAIRYAAMAH
SGYFPVEDLLTFRKLGSKLQGHPSTRYMNGIESSSGSLGQGLSVSVGLALGARFKKQSHKIYTCISDGECGEGMTWEAAQ
SATHYKLDNLIAFMDKNGIQIDGFTKDVMNLEPLSKKFLSFGWNVLEADGHDIEQIISAFEKAKLHKGSPTIILFDTILG
KGVSFMENNPGWHGTPPKPEEEKKALEELSALSV

Sequences:

>Translated_274_residues
MNDIKELKNFANELRKSVIRMVTAANSGHPGGPLGLADIYAVLYKKILNHKPSNPDWEGRDRLVLSNGHVCAIRYAAMAH
SGYFPVEDLLTFRKLGSKLQGHPSTRYMNGIESSSGSLGQGLSVSVGLALGARFKKQSHKIYTCISDGECGEGMTWEAAQ
SATHYKLDNLIAFMDKNGIQIDGFTKDVMNLEPLSKKFLSFGWNVLEADGHDIEQIISAFEKAKLHKGSPTIILFDTILG
KGVSFMENNPGWHGTPPKPEEEKKALEELSALSV
>Mature_274_residues
MNDIKELKNFANELRKSVIRMVTAANSGHPGGPLGLADIYAVLYKKILNHKPSNPDWEGRDRLVLSNGHVCAIRYAAMAH
SGYFPVEDLLTFRKLGSKLQGHPSTRYMNGIESSSGSLGQGLSVSVGLALGARFKKQSHKIYTCISDGECGEGMTWEAAQ
SATHYKLDNLIAFMDKNGIQIDGFTKDVMNLEPLSKKFLSFGWNVLEADGHDIEQIISAFEKAKLHKGSPTIILFDTILG
KGVSFMENNPGWHGTPPKPEEEKKALEELSALSV

Specific function: Unknown

COG id: COG3959

COG function: function code G; Transketolase, N-terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=267, Percent_Identity=37.4531835205993, Blast_Score=180, Evalue=1e-45,
Organism=Homo sapiens, GI4507521, Length=267, Percent_Identity=37.4531835205993, Blast_Score=180, Evalue=1e-45,
Organism=Homo sapiens, GI133778974, Length=267, Percent_Identity=35.5805243445693, Blast_Score=171, Evalue=8e-43,
Organism=Homo sapiens, GI225637459, Length=267, Percent_Identity=28.4644194756554, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI225637461, Length=267, Percent_Identity=27.7153558052434, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI225637463, Length=230, Percent_Identity=28.2608695652174, Blast_Score=107, Evalue=1e-23,
Organism=Escherichia coli, GI48994911, Length=266, Percent_Identity=39.8496240601504, Blast_Score=184, Evalue=6e-48,
Organism=Escherichia coli, GI1788808, Length=274, Percent_Identity=39.051094890511, Blast_Score=184, Evalue=8e-48,
Organism=Caenorhabditis elegans, GI17539652, Length=252, Percent_Identity=38.8888888888889, Blast_Score=196, Evalue=7e-51,
Organism=Saccharomyces cerevisiae, GI6319593, Length=277, Percent_Identity=39.7111913357401, Blast_Score=174, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6325331, Length=277, Percent_Identity=39.3501805054152, Blast_Score=172, Evalue=5e-44,
Organism=Drosophila melanogaster, GI45551847, Length=269, Percent_Identity=38.2899628252788, Blast_Score=183, Evalue=1e-46,
Organism=Drosophila melanogaster, GI45550715, Length=269, Percent_Identity=38.2899628252788, Blast_Score=183, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24666278, Length=255, Percent_Identity=39.2156862745098, Blast_Score=173, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24645119, Length=232, Percent_Identity=38.7931034482759, Blast_Score=159, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 30062; Mature: 30062

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDIKELKNFANELRKSVIRMVTAANSGHPGGPLGLADIYAVLYKKILNHKPSNPDWEGR
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
DRLVLSNGHVCAIRYAAMAHSGYFPVEDLLTFRKLGSKLQGHPSTRYMNGIESSSGSLGQ
CEEEEECCCEEEEEHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCC
GLSVSVGLALGARFKKQSHKIYTCISDGECGEGMTWEAAQSATHYKLDNLIAFMDKNGIQ
CCEEEHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHCCHHHHHHHHHHHHCCCCCE
IDGFTKDVMNLEPLSKKFLSFGWNVLEADGHDIEQIISAFEKAKLHKGSPTIILFDTILG
ECCCHHHHHCCCHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEECHHC
KGVSFMENNPGWHGTPPKPEEEKKALEELSALSV
CCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNDIKELKNFANELRKSVIRMVTAANSGHPGGPLGLADIYAVLYKKILNHKPSNPDWEGR
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
DRLVLSNGHVCAIRYAAMAHSGYFPVEDLLTFRKLGSKLQGHPSTRYMNGIESSSGSLGQ
CEEEEECCCEEEEEHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCC
GLSVSVGLALGARFKKQSHKIYTCISDGECGEGMTWEAAQSATHYKLDNLIAFMDKNGIQ
CCEEEHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHCCHHHHHHHHHHHHCCCCCE
IDGFTKDVMNLEPLSKKFLSFGWNVLEADGHDIEQIISAFEKAKLHKGSPTIILFDTILG
ECCCHHHHHCCCHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEECHHC
KGVSFMENNPGWHGTPPKPEEEKKALEELSALSV
CCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]