| Definition | Leptospira borgpetersenii serovar Hardjo-bovis L550 chromosome 1, complete sequence. |
|---|---|
| Accession | NC_008508 |
| Length | 3,614,446 |
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The map label for this gene is ponA [H]
Identifier: 116327214
GI number: 116327214
Start: 470850
End: 473276
Strand: Reverse
Name: ponA [H]
Synonym: LBL_0402
Alternate gene names: 116327214
Gene position: 473276-470850 (Counterclockwise)
Preceding gene: 116327215
Following gene: 116327212
Centisome position: 13.09
GC content: 42.81
Gene sequence:
>2427_bases ATGGCATTCGGTAATGACAAAATATTCTCCATTTTTAATGCGCTCAAGAAAGGTTTTACGGGCTTTTTCCTTTTCATAAA AACGTATTGGAGATTCATATTCCGTTATGCGATCGTTGTTATCATTGCGCTCGTTTCTTTTTTGATTGGCGGTTCTTACG TGGTTTGGTTAACCAAAAAGGACGAAATCGTTTCCAATCTGGATAAATTCAAAAACGAAGTCACAAATTATTACGAAATC AGTCAGATTCGTCCTATCCGAATTTTGGATCGAAACAGAAAGTTAATCGGGGAATTTTCGAGGAGAAAGTTTAAACCGAT CCGCACTGACAATCTCGCAGAACACGGGAACATCATTTGGGCGCTTCTTTCTTCCGAAGATAGGGAGTTTTACAATCATC ACGGAATCAATTACGCCGCGCTTTTACGGGCAATCATTATCAATCTCACCACTTTTCAAAAACAGGGCGGGTCCACGATT ACTCAGCAGCTCGCAAAACTGACTTTGGATCTGGGAGCCAGAAATATCTTTAATAAAATTACGGAATTCTATTGTACCTT TTATCTTGAGAGCCAGTTTGACAAGAATACGATTCTTTCCATGTATCTCAATCGGATTTTCTTAGGCGAGGGAAATACGG GAGTGGAGGAGGCTAGTCGTTACTATTTCAATAAGGCCGCCGCCGAACTTACTCCGGAAGAAGCGGCTATGCTCGTCGGG ATCATTCCGGCGCCTTCCAACTACAATCCTGTTCGAAGTTTAAAGACCGCTCTCAAAAGACAAAAGTTGGTTCTTACTCC TATGTCCGAAAATCAACATCTGCATCCTGATCCTTCCGGTATTGAAAGGAACTTCTCTCAAAAGATCGATGCAAATCTAA AAAAATTCAAAACCTTCTACAATGTCGAACTCACAAAAGACGGAGAGAAGGAATTTTATTCTTCCGATATCGCTAGATAC GGTTTTGATAAGGACTTTACAGTCAATCTTGCCCCCGATTTTAATTACGGAATCCGCCAACGTATTTTGGATACATTTTC AGAGGTCGATATCGAAACCAGAGGGATGAACGTTTATACAACTCTTGACTACGATAAACAAAACGTCGCCGAAAAGTCCT TAAGAGAAGGGATCGAATCCGTCCGTAAAAAACTGAACGATGTAAAGGCCGCCTACGTGAAAAAAGGTAATTCGGAAGAG GTAAGAGTTCAACAATCCATCATAGATAACATGAACGGATCCTTGATTTCAATCAATCCCGGAAACGGTTATGTCGAGGC GATGGTTGGTAGTTACAAAATCTCTAATATATTTAGACTTAATCGAGCGGTCTCCGCGCTCAGACAACCCGGTTCCACAA TCAAGGCTTTAATTTACGCAATCGCGTTTGAAAATAGGATTATTACTCCTTCGTCCACGGTTGTGGATGAGGAAATTAAC ATCCGAGGTTATTCTCCGAGAAATTGGTACAAAGGTTATAAAGGGGAAATCACCGCCAGAGTCGCGTTTGCACAATCGGT CAATACGATCGCGGTGAAATTGTTAAACGAATTCGGTGTGAACGACTTTTTGGAAAAAATTGCGACGATCTTGGATATAG ACAAGGCGACTCTTGAAAAAAGATTCCAACCGAATCTTTCTTTGGCTCTCGGCTCGGGAGAATTGTCGCCGATGGAACTT GCTTTGATTTATGCGACGATTGCAAATGGAGGAAAAAAAGTTACCCCCGTTCAAATCCTAAGAATTACGGATTTTGAAGG AAGTGAAATGTTTTCCACACCTTTGAAAGATCCGAATGAAGCGATTCAGGTCTTAGATCCGGTTGCGTGTGCGGAAACGA TCAATCTTTTAGAAGCGGTGTTAAGCGAACAAGGAACGATGAAACTTAAATTGAAAGACGAAGACTTTTTTCCGATGGGC GGTAAAACGGGAACAGTTCAGTCTCCGAAAGAAGTCCGTAAAAAATGGGGATCCCGTAAGGGAGTAAGAGACGCCTGGTT TGCCGGCGTGAACCCCGATTTAGTTACAACAGTCTGGATCGGTAACGACGTGGGCGCTCCGTTTGAAGGTTCGGGTTCTG GAATCAGCGGAAACGTCTGGTTTCGTTATGTGAACTATATCGCAAAAAACATCGGATTTTCAGAAACGCTTGTCAAGCCG TTTAACGGCGATTTTGTGAGAGTCGATGTATGTGGAGAGACCGGCTTGCTTCTGCATTCGTCCGTCCCTTGTTTGTATCC CTTGTACGGTCAGTACTATTATATCGGGGAACAACCTTCCGCTCCTGTCCCTGCAGCTTCGGAAAATTTCACACAAAAGT CGGAGACGGTTACTACCGAAAAAACGATTCTTCCTCAAGGGGAAGAGAGCGACGCGGATTCTGTCGAACTTGAACTTCCG GAAGTTACAGATAATCCTCCAAATTAG
Upstream 100 bases:
>100_bases CGTCTCAAAAATCTTTTTGTTGCTTCAAAACCTAGTGCGAAGGGATGAAAGCTTCTTTTTGAGATGATCTTTCGTAGAAT ATTGGACTTTAGGACAGGCG
Downstream 100 bases:
>100_bases AATAACGTTTTCCCTTTTCAGATATTAGAAAAGTCTCATGCGGTGACCAAAGATAAATCCAAGGATTTTCTCTGAGAAGA ATTTGCAAAGCTTTGGTCGT
Product: penicillin binding protein 1
Products: NA
Alternate protein names: PBP-1a; PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 808; Mature: 807
Protein sequence:
>808_residues MAFGNDKIFSIFNALKKGFTGFFLFIKTYWRFIFRYAIVVIIALVSFLIGGSYVVWLTKKDEIVSNLDKFKNEVTNYYEI SQIRPIRILDRNRKLIGEFSRRKFKPIRTDNLAEHGNIIWALLSSEDREFYNHHGINYAALLRAIIINLTTFQKQGGSTI TQQLAKLTLDLGARNIFNKITEFYCTFYLESQFDKNTILSMYLNRIFLGEGNTGVEEASRYYFNKAAAELTPEEAAMLVG IIPAPSNYNPVRSLKTALKRQKLVLTPMSENQHLHPDPSGIERNFSQKIDANLKKFKTFYNVELTKDGEKEFYSSDIARY GFDKDFTVNLAPDFNYGIRQRILDTFSEVDIETRGMNVYTTLDYDKQNVAEKSLREGIESVRKKLNDVKAAYVKKGNSEE VRVQQSIIDNMNGSLISINPGNGYVEAMVGSYKISNIFRLNRAVSALRQPGSTIKALIYAIAFENRIITPSSTVVDEEIN IRGYSPRNWYKGYKGEITARVAFAQSVNTIAVKLLNEFGVNDFLEKIATILDIDKATLEKRFQPNLSLALGSGELSPMEL ALIYATIANGGKKVTPVQILRITDFEGSEMFSTPLKDPNEAIQVLDPVACAETINLLEAVLSEQGTMKLKLKDEDFFPMG GKTGTVQSPKEVRKKWGSRKGVRDAWFAGVNPDLVTTVWIGNDVGAPFEGSGSGISGNVWFRYVNYIAKNIGFSETLVKP FNGDFVRVDVCGETGLLLHSSVPCLYPLYGQYYYIGEQPSAPVPAASENFTQKSETVTTEKTILPQGEESDADSVELELP EVTDNPPN
Sequences:
>Translated_808_residues MAFGNDKIFSIFNALKKGFTGFFLFIKTYWRFIFRYAIVVIIALVSFLIGGSYVVWLTKKDEIVSNLDKFKNEVTNYYEI SQIRPIRILDRNRKLIGEFSRRKFKPIRTDNLAEHGNIIWALLSSEDREFYNHHGINYAALLRAIIINLTTFQKQGGSTI TQQLAKLTLDLGARNIFNKITEFYCTFYLESQFDKNTILSMYLNRIFLGEGNTGVEEASRYYFNKAAAELTPEEAAMLVG IIPAPSNYNPVRSLKTALKRQKLVLTPMSENQHLHPDPSGIERNFSQKIDANLKKFKTFYNVELTKDGEKEFYSSDIARY GFDKDFTVNLAPDFNYGIRQRILDTFSEVDIETRGMNVYTTLDYDKQNVAEKSLREGIESVRKKLNDVKAAYVKKGNSEE VRVQQSIIDNMNGSLISINPGNGYVEAMVGSYKISNIFRLNRAVSALRQPGSTIKALIYAIAFENRIITPSSTVVDEEIN IRGYSPRNWYKGYKGEITARVAFAQSVNTIAVKLLNEFGVNDFLEKIATILDIDKATLEKRFQPNLSLALGSGELSPMEL ALIYATIANGGKKVTPVQILRITDFEGSEMFSTPLKDPNEAIQVLDPVACAETINLLEAVLSEQGTMKLKLKDEDFFPMG GKTGTVQSPKEVRKKWGSRKGVRDAWFAGVNPDLVTTVWIGNDVGAPFEGSGSGISGNVWFRYVNYIAKNIGFSETLVKP FNGDFVRVDVCGETGLLLHSSVPCLYPLYGQYYYIGEQPSAPVPAASENFTQKSETVTTEKTILPQGEESDADSVELELP EVTDNPPN >Mature_807_residues AFGNDKIFSIFNALKKGFTGFFLFIKTYWRFIFRYAIVVIIALVSFLIGGSYVVWLTKKDEIVSNLDKFKNEVTNYYEIS QIRPIRILDRNRKLIGEFSRRKFKPIRTDNLAEHGNIIWALLSSEDREFYNHHGINYAALLRAIIINLTTFQKQGGSTIT QQLAKLTLDLGARNIFNKITEFYCTFYLESQFDKNTILSMYLNRIFLGEGNTGVEEASRYYFNKAAAELTPEEAAMLVGI IPAPSNYNPVRSLKTALKRQKLVLTPMSENQHLHPDPSGIERNFSQKIDANLKKFKTFYNVELTKDGEKEFYSSDIARYG FDKDFTVNLAPDFNYGIRQRILDTFSEVDIETRGMNVYTTLDYDKQNVAEKSLREGIESVRKKLNDVKAAYVKKGNSEEV RVQQSIIDNMNGSLISINPGNGYVEAMVGSYKISNIFRLNRAVSALRQPGSTIKALIYAIAFENRIITPSSTVVDEEINI RGYSPRNWYKGYKGEITARVAFAQSVNTIAVKLLNEFGVNDFLEKIATILDIDKATLEKRFQPNLSLALGSGELSPMELA LIYATIANGGKKVTPVQILRITDFEGSEMFSTPLKDPNEAIQVLDPVACAETINLLEAVLSEQGTMKLKLKDEDFFPMGG KTGTVQSPKEVRKKWGSRKGVRDAWFAGVNPDLVTTVWIGNDVGAPFEGSGSGISGNVWFRYVNYIAKNIGFSETLVKPF NGDFVRVDVCGETGLLLHSSVPCLYPLYGQYYYIGEQPSAPVPAASENFTQKSETVTTEKTILPQGEESDADSVELELPE VTDNPPN
Specific function: Cell Wall Formation. Synthesis Of Cross-Linked Peptidoglycan From The Lipid Intermediates. The Enzyme Has A Penicillin-Insensitive Transglycosylase N-Terminal Domain (Formation Of Linear Glycan Strands) And A Penicillin-Sensitive Transpeptidase C-Terminal
COG id: COG0744
COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI87082258, Length=766, Percent_Identity=24.8041775456919, Blast_Score=193, Evalue=3e-50, Organism=Escherichia coli, GI1786343, Length=600, Percent_Identity=26.5, Blast_Score=166, Evalue=5e-42, Organism=Escherichia coli, GI1788867, Length=577, Percent_Identity=26.1698440207972, Blast_Score=133, Evalue=5e-32, Organism=Escherichia coli, GI1789601, Length=151, Percent_Identity=33.112582781457, Blast_Score=81, Evalue=2e-16,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-; 3.4.-.- [C]
Molecular weight: Translated: 90839; Mature: 90707
Theoretical pI: Translated: 7.12; Mature: 7.12
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 1.4 %Met (Translated Protein) 1.9 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 1.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAFGNDKIFSIFNALKKGFTGFFLFIKTYWRFIFRYAIVVIIALVSFLIGGSYVVWLTKK CCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECH DEIVSNLDKFKNEVTNYYEISQIRPIRILDRNRKLIGEFSRRKFKPIRTDNLAEHGNIIW HHHHHHHHHHHHHHCCEEECCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCHHCCCEEE ALLSSEDREFYNHHGINYAALLRAIIINLTTFQKQGGSTITQQLAKLTLDLGARNIFNKI EEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH TEFYCTFYLESQFDKNTILSMYLNRIFLGEGNTGVEEASRYYFNKAAAELTPEEAAMLVG HHHHHHEEECCCCCCHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHCCHHHCEEEEE IIPAPSNYNPVRSLKTALKRQKLVLTPMSENQHLHPDPSGIERNFSQKIDANLKKFKTFY EECCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEE NVELTKDGEKEFYSSDIARYGFDKDFTVNLAPDFNYGIRQRILDTFSEVDIETRGMNVYT EEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCEEECCCEEEE TLDYDKQNVAEKSLREGIESVRKKLNDVKAAYVKKGNSEEVRVQQSIIDNMNGSLISINP EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEECC GNGYVEAMVGSYKISNIFRLNRAVSALRQPGSTIKALIYAIAFENRIITPSSTVVDEEIN CCCEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEEECCCCCEECCCCC IRGYSPRNWYKGYKGEITARVAFAQSVNTIAVKLLNEFGVNDFLEKIATILDIDKATLEK EECCCCHHHCCCCCCCEEEEEEEHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHH RFQPNLSLALGSGELSPMELALIYATIANGGKKVTPVQILRITDFEGSEMFSTPLKDPNE HCCCCCEEEECCCCCCHHHHEEEEEEHHCCCCEECCEEEEEEECCCCCCCCCCCCCCHHH AIQVLDPVACAETINLLEAVLSEQGTMKLKLKDEDFFPMGGKTGTVQSPKEVRKKWGSRK HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCC GVRDAWFAGVNPDLVTTVWIGNDVGAPFEGSGSGISGNVWFRYVNYIAKNIGFSETLVKP CCCHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCC FNGDFVRVDVCGETGLLLHSSVPCLYPLYGQYYYIGEQPSAPVPAASENFTQKSETVTTE CCCCEEEEEECCCCCEEEECCCCCEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCEECC KTILPQGEESDADSVELELPEVTDNPPN CEECCCCCCCCCCCEEEECCCCCCCCCC >Mature Secondary Structure AFGNDKIFSIFNALKKGFTGFFLFIKTYWRFIFRYAIVVIIALVSFLIGGSYVVWLTKK CCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECH DEIVSNLDKFKNEVTNYYEISQIRPIRILDRNRKLIGEFSRRKFKPIRTDNLAEHGNIIW HHHHHHHHHHHHHHCCEEECCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCHHCCCEEE ALLSSEDREFYNHHGINYAALLRAIIINLTTFQKQGGSTITQQLAKLTLDLGARNIFNKI EEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH TEFYCTFYLESQFDKNTILSMYLNRIFLGEGNTGVEEASRYYFNKAAAELTPEEAAMLVG HHHHHHEEECCCCCCHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHCCHHHCEEEEE IIPAPSNYNPVRSLKTALKRQKLVLTPMSENQHLHPDPSGIERNFSQKIDANLKKFKTFY EECCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEE NVELTKDGEKEFYSSDIARYGFDKDFTVNLAPDFNYGIRQRILDTFSEVDIETRGMNVYT EEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCEEECCCEEEE TLDYDKQNVAEKSLREGIESVRKKLNDVKAAYVKKGNSEEVRVQQSIIDNMNGSLISINP EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEECC GNGYVEAMVGSYKISNIFRLNRAVSALRQPGSTIKALIYAIAFENRIITPSSTVVDEEIN CCCEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEEECCCCCEECCCCC IRGYSPRNWYKGYKGEITARVAFAQSVNTIAVKLLNEFGVNDFLEKIATILDIDKATLEK EECCCCHHHCCCCCCCEEEEEEEHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHH RFQPNLSLALGSGELSPMELALIYATIANGGKKVTPVQILRITDFEGSEMFSTPLKDPNE HCCCCCEEEECCCCCCHHHHEEEEEEHHCCCCEECCEEEEEEECCCCCCCCCCCCCCHHH AIQVLDPVACAETINLLEAVLSEQGTMKLKLKDEDFFPMGGKTGTVQSPKEVRKKWGSRK HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCC GVRDAWFAGVNPDLVTTVWIGNDVGAPFEGSGSGISGNVWFRYVNYIAKNIGFSETLVKP CCCHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCC FNGDFVRVDVCGETGLLLHSSVPCLYPLYGQYYYIGEQPSAPVPAASENFTQKSETVTTE CCCCEEEEEECCCCCEEEECCCCCEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCEECC KTILPQGEESDADSVELELPEVTDNPPN CEECCCCCCCCCCCEEEECCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 9537320 [H]