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The map label for this gene is tpx [H]

Identifier: 116327207

GI number: 116327207

Start: 461472

End: 461987

Strand: Direct

Name: tpx [H]

Synonym: LBL_0394

Alternate gene names: 116327207

Gene position: 461472-461987 (Clockwise)

Preceding gene: 116327206

Following gene: 116327209

Centisome position: 12.77

GC content: 45.54

Gene sequence:

>516_bases
ATGACACAAGTTACACTCAAAGGCAATCCGGTATCGTTAGAAGGAAAAATTCCTGTTCCGGGGGATAAGGCTCCTGACTT
CAAAGTGATCAAACAAGATCTCTCGGAATTCAGTCTTAAAGATTACTCGGGTAAAGTGAAAATTCTCGTAGCCGTTCCGA
GTTGGGACACTTCGGTCTGTGCTCTGGAAACCAGAGTATTCAACGAAAAAGCAGCAGGACTTTCCGACATTACAACTTTG
ATTATCTCGGGCGACTTACCCTTTGCGATGAAACGTTTTTGTTCCACGGAAGGAATCAATTCTCCGAACCTCATAACAGG
GTCTCAATTTAGAGATTTCTCGTTTTCAAAAGCGTACGGAACTCATATCGCAGACGGTCCGCTCAAAGGACTCTCGGCAA
GAGCGGTTTTTGTCGTGGATAAATCGGATATAGTTCGTTACGTAGAACTTGTTTCCGAAATCGGGTCGGAGCCGAATTAC
GAAGCGGCACTTACCGCGGCTAAGGCAGCACTGTAA

Upstream 100 bases:

>100_bases
ATTTTGTAAAAAATCGACTTTAAGTTCAGACTTAAAATCCCGAGTCGTAAAACGATTTTTCGTATATTCTTTAAACATAA
TATTACTTAGGAAAATTTAA

Downstream 100 bases:

>100_bases
TCTTTACGGCTTGTTCGGATCGAATACCAAGCCGTAAAGATGATACATGAGAAAGTCAATCGAATCTCTACATAAATGAA
TCTTATGACAACACTTCTAA

Product: thiol peroxidase

Products: oxidized thioredoxin; H2O [C]

Alternate protein names: NA

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MTQVTLKGNPVSLEGKIPVPGDKAPDFKVIKQDLSEFSLKDYSGKVKILVAVPSWDTSVCALETRVFNEKAAGLSDITTL
IISGDLPFAMKRFCSTEGINSPNLITGSQFRDFSFSKAYGTHIADGPLKGLSARAVFVVDKSDIVRYVELVSEIGSEPNY
EAALTAAKAAL

Sequences:

>Translated_171_residues
MTQVTLKGNPVSLEGKIPVPGDKAPDFKVIKQDLSEFSLKDYSGKVKILVAVPSWDTSVCALETRVFNEKAAGLSDITTL
IISGDLPFAMKRFCSTEGINSPNLITGSQFRDFSFSKAYGTHIADGPLKGLSARAVFVVDKSDIVRYVELVSEIGSEPNY
EAALTAAKAAL
>Mature_170_residues
TQVTLKGNPVSLEGKIPVPGDKAPDFKVIKQDLSEFSLKDYSGKVKILVAVPSWDTSVCALETRVFNEKAAGLSDITTLI
ISGDLPFAMKRFCSTEGINSPNLITGSQFRDFSFSKAYGTHIADGPLKGLSARAVFVVDKSDIVRYVELVSEIGSEPNYE
AALTAAKAAL

Specific function: Has antioxidant activity. Could remove peroxides or H(2)O(2) [H]

COG id: COG2077

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1787584, Length=170, Percent_Identity=50.5882352941176, Blast_Score=167, Evalue=3e-43,

Paralogues:

None

Copy number: 2480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018219
- InterPro:   IPR002065
- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: 1.11.1.- [C]

Molecular weight: Translated: 18362; Mature: 18231

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS01265 TPX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQVTLKGNPVSLEGKIPVPGDKAPDFKVIKQDLSEFSLKDYSGKVKILVAVPSWDTSVC
CCEEEECCCCEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCEE
ALETRVFNEKAAGLSDITTLIISGDLPFAMKRFCSTEGINSPNLITGSQFRDFSFSKAYG
EHHHHHHCCHHCCHHHEEEEEEECCCCHHHHHHHHHCCCCCCCEEECCCCCCCCCCHHCC
THIADGPLKGLSARAVFVVDKSDIVRYVELVSEIGSEPNYEAALTAAKAAL
CCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
TQVTLKGNPVSLEGKIPVPGDKAPDFKVIKQDLSEFSLKDYSGKVKILVAVPSWDTSVC
CEEEECCCCEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCEE
ALETRVFNEKAAGLSDITTLIISGDLPFAMKRFCSTEGINSPNLITGSQFRDFSFSKAYG
EHHHHHHCCHHCCHHHEEEEEEECCCCHHHHHHHHHCCCCCCCEEECCCCCCCCCCHHCC
THIADGPLKGLSARAVFVVDKSDIVRYVELVSEIGSEPNYEAALTAAKAAL
CCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: reduced thioredoxin; H2O2 [C]

Specific reaction: reduced thioredoxin + H2O2 = oxidized thioredoxin + H2O [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA