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The map label for this gene is luxQ [H]

Identifier: 116327206

GI number: 116327206

Start: 458884

End: 460578

Strand: Direct

Name: luxQ [H]

Synonym: LBL_0393

Alternate gene names: 116327206

Gene position: 458884-460578 (Clockwise)

Preceding gene: 116327205

Following gene: 116327207

Centisome position: 12.7

GC content: 39.59

Gene sequence:

>1695_bases
ATGGAAACATCTAAGAATCATTCAATTCCAATTCCGTTTAACGAGAAGGAAAGACTCGATGCCCTACATTCTTATCAGAT
CATAAACACGACTCCAGAAGAAAAATTCGATTCTCTTACACAAATAGCGGCCTATATCTGTGATTCTCCGATCGTACTTA
TTTCCTTGATCGATACGAATCGACTTTGGTTCAAATCGAAAATCGGAATGAACGTTTCCGGAATTCCACGAGACATTTCG
TTCTGCCAATACACAATTATTCAAGATGAAATTTTCGAAATCGAAAACGCTTTAAACGACGAAAAATTTCAAAATAACCC
CTTCGTTTTAGGACCGCCTTATATTCGTTTTTATGCGGGTACACCCCTAAAAACACCCGAAGGATTCAATGTCGGAACTC
TTTGTGTATTCGACACTGAACCGAAAAGATTGGATTCCAGACAGAAAATGACTCTAAAAGTGTTATCCAATCAGATCATC
GCAAACTTCGAGTTGATTAAAAAAAACCGGGAATTAGTTTCAGTCCACGAAAAAAAGGAAGAACTCCAAAAATCCAAAAG
TCAATTTTTCGCGAATATGAGCCATGAAATCCGCACTCCGGTTCACGGAATCTTAGGAATCACGAGTCTGTTATCGGAAA
CGAAACTTCAACCGGAACAAAAAGAATACGTCGACATAATCCGAAGAAACGGCAACCTTTTACTTAGCCTTTTAAATGAT
ATTTTAGATTTTTCTAAATTAGAATCGTCTCATATGAAAATCGAAATAATAGCCTTTGATCTTATGGATTTACTAAAGGA
CGTGTTCTATCTTTTTGAGACGGATGCAAAACGTAAAAATTTGGAATTCAAAATGGTCGGAGATACACTTTCTTCTTTGA
TCGTTTCTACGGATCCGAATCGGTTGAAACAGATTCTAGTCAACCTCATCTCAAACGCATTCAAATCCACCGAAAAAGGA
AGTGTATCGATCGAGTTTGAATTCGACATCAAATCCGATTCGAAACAATGCGATATACGGATTCGGGTAAAGGACACCGG
AATCGGGATACCGGAGCAAAAACTAAAAGAGTTATTCCAAGCCTATAGTCAGATGGATACTTCCGTTTCGAGAAAATACG
GAGGAACCGGACTCGGCCTTGCGATCAGCAAAGGTCTTGCAGAAATGATGAATTTAAAACTGACCGCACAAAGCGTCATA
AATCGAGGAAGCGTTTTTGAAATTTCGGGCAGGATTCCTCTCGCTGAAAGGTCGGAAGTAAACTTCGAACCCAAAAAACC
AAACCCCGATACAAACGGCGCCTCTGTTCAAGACCTAAGAATCCTTGTAGCCGAGGATAACGAAATCAATCAAATGCTGA
TCAAAAAAGTTTTAGAAAAGTTAGGATACAAACCGGTGATCGTCTCCAACGGGATCGAAGCGCTGCATCACATAGAAACA
AAGGGAGCGGATGTTTTTTTTCTGGACATTCAAATGCCGGAATTAAGCGGAATCGAAACTGCTAAAATTCTTACACAACA
TACCAATCAGTCTATTCGTCCTTATATCATTGCTATGACCGCTAACGCGAGCCCAGAGGACAAGGAGGACTGTCTGGCGT
CCGGCATTAATGAATATATCAGCAAACCGTTTCGTAAAGAGGAAATCGCCGATCTACTGAATCATTTTATTGCCAGAAAA
AACTCTAAAACATAA

Upstream 100 bases:

>100_bases
GTTCTCCCAAACACTTTCAAATCATTCGAATTTAATTTTTCGATTCAAATTCCTCTTGCTTAATTTATTTTTTTAGAAAG
AATATTCTCGGTTTGAATCC

Downstream 100 bases:

>100_bases
AAACAATTTCACCCCGATGTAACTTGCAATTCGATAAATCGAGGTCGACAACCTTTGAACTTTAACTTCGGCCTTTTTAA
CCTGAGTTTGGTGTAACAAA

Product: sensor histidine kinase and response regulator of a two component complex

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 564; Mature: 564

Protein sequence:

>564_residues
METSKNHSIPIPFNEKERLDALHSYQIINTTPEEKFDSLTQIAAYICDSPIVLISLIDTNRLWFKSKIGMNVSGIPRDIS
FCQYTIIQDEIFEIENALNDEKFQNNPFVLGPPYIRFYAGTPLKTPEGFNVGTLCVFDTEPKRLDSRQKMTLKVLSNQII
ANFELIKKNRELVSVHEKKEELQKSKSQFFANMSHEIRTPVHGILGITSLLSETKLQPEQKEYVDIIRRNGNLLLSLLND
ILDFSKLESSHMKIEIIAFDLMDLLKDVFYLFETDAKRKNLEFKMVGDTLSSLIVSTDPNRLKQILVNLISNAFKSTEKG
SVSIEFEFDIKSDSKQCDIRIRVKDTGIGIPEQKLKELFQAYSQMDTSVSRKYGGTGLGLAISKGLAEMMNLKLTAQSVI
NRGSVFEISGRIPLAERSEVNFEPKKPNPDTNGASVQDLRILVAEDNEINQMLIKKVLEKLGYKPVIVSNGIEALHHIET
KGADVFFLDIQMPELSGIETAKILTQHTNQSIRPYIIAMTANASPEDKEDCLASGINEYISKPFRKEEIADLLNHFIARK
NSKT

Sequences:

>Translated_564_residues
METSKNHSIPIPFNEKERLDALHSYQIINTTPEEKFDSLTQIAAYICDSPIVLISLIDTNRLWFKSKIGMNVSGIPRDIS
FCQYTIIQDEIFEIENALNDEKFQNNPFVLGPPYIRFYAGTPLKTPEGFNVGTLCVFDTEPKRLDSRQKMTLKVLSNQII
ANFELIKKNRELVSVHEKKEELQKSKSQFFANMSHEIRTPVHGILGITSLLSETKLQPEQKEYVDIIRRNGNLLLSLLND
ILDFSKLESSHMKIEIIAFDLMDLLKDVFYLFETDAKRKNLEFKMVGDTLSSLIVSTDPNRLKQILVNLISNAFKSTEKG
SVSIEFEFDIKSDSKQCDIRIRVKDTGIGIPEQKLKELFQAYSQMDTSVSRKYGGTGLGLAISKGLAEMMNLKLTAQSVI
NRGSVFEISGRIPLAERSEVNFEPKKPNPDTNGASVQDLRILVAEDNEINQMLIKKVLEKLGYKPVIVSNGIEALHHIET
KGADVFFLDIQMPELSGIETAKILTQHTNQSIRPYIIAMTANASPEDKEDCLASGINEYISKPFRKEEIADLLNHFIARK
NSKT
>Mature_564_residues
METSKNHSIPIPFNEKERLDALHSYQIINTTPEEKFDSLTQIAAYICDSPIVLISLIDTNRLWFKSKIGMNVSGIPRDIS
FCQYTIIQDEIFEIENALNDEKFQNNPFVLGPPYIRFYAGTPLKTPEGFNVGTLCVFDTEPKRLDSRQKMTLKVLSNQII
ANFELIKKNRELVSVHEKKEELQKSKSQFFANMSHEIRTPVHGILGITSLLSETKLQPEQKEYVDIIRRNGNLLLSLLND
ILDFSKLESSHMKIEIIAFDLMDLLKDVFYLFETDAKRKNLEFKMVGDTLSSLIVSTDPNRLKQILVNLISNAFKSTEKG
SVSIEFEFDIKSDSKQCDIRIRVKDTGIGIPEQKLKELFQAYSQMDTSVSRKYGGTGLGLAISKGLAEMMNLKLTAQSVI
NRGSVFEISGRIPLAERSEVNFEPKKPNPDTNGASVQDLRILVAEDNEINQMLIKKVLEKLGYKPVIVSNGIEALHHIET
KGADVFFLDIQMPELSGIETAKILTQHTNQSIRPYIIAMTANASPEDKEDCLASGINEYISKPFRKEEIADLLNHFIARK
NSKT

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=380, Percent_Identity=32.8947368421053, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1789149, Length=239, Percent_Identity=42.2594142259414, Blast_Score=188, Evalue=1e-48,
Organism=Escherichia coli, GI1788713, Length=391, Percent_Identity=32.9923273657289, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI87081816, Length=398, Percent_Identity=31.4070351758794, Blast_Score=171, Evalue=2e-43,
Organism=Escherichia coli, GI145693157, Length=249, Percent_Identity=35.3413654618474, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1786783, Length=239, Percent_Identity=28.4518828451883, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1786600, Length=244, Percent_Identity=25.8196721311475, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1790436, Length=243, Percent_Identity=25.1028806584362, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788393, Length=228, Percent_Identity=25.4385964912281, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788549, Length=225, Percent_Identity=24.8888888888889, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790300, Length=238, Percent_Identity=25.6302521008403, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87082128, Length=235, Percent_Identity=25.531914893617, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790861, Length=217, Percent_Identity=25.3456221198157, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790346, Length=209, Percent_Identity=28.2296650717703, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=150, Percent_Identity=32, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322000, Length=128, Percent_Identity=30.46875, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 63861; Mature: 63861

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METSKNHSIPIPFNEKERLDALHSYQIINTTPEEKFDSLTQIAAYICDSPIVLISLIDTN
CCCCCCCCCCCCCCCHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEECCC
RLWFKSKIGMNVSGIPRDISFCQYTIIQDEIFEIENALNDEKFQNNPFVLGPPYIRFYAG
CEEEEHCCCCCCCCCCCCCHHHEEEHHHHHHHHHHHHCCCCCCCCCCEEECCCCEEEEEC
TPLKTPEGFNVGTLCVFDTEPKRLDSRQKMTLKVLSNQIIANFELIKKNRELVSVHEKKE
CCCCCCCCCCCEEEEEECCCCHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
ELQKSKSQFFANMSHEIRTPVHGILGITSLLSETKLQPEQKEYVDIIRRNGNLLLSLLND
HHHHHHHHHHHHCHHHHHCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHH
ILDFSKLESSHMKIEIIAFDLMDLLKDVFYLFETDAKRKNLEFKMVGDTLSSLIVSTDPN
HHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHCCCCHH
RLKQILVNLISNAFKSTEKGSVSIEFEFDIKSDSKQCDIRIRVKDTGIGIPEQKLKELFQ
HHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCEEEEEEEEEECCCCCCHHHHHHHHH
AYSQMDTSVSRKYGGTGLGLAISKGLAEMMNLKLTAQSVINRGSVFEISGRIPLAERSEV
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCC
NFEPKKPNPDTNGASVQDLRILVAEDNEINQMLIKKVLEKLGYKPVIVSNGIEALHHIET
CCCCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHC
KGADVFFLDIQMPELSGIETAKILTQHTNQSIRPYIIAMTANASPEDKEDCLASGINEYI
CCCEEEEEEEECCCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHH
SKPFRKEEIADLLNHFIARKNSKT
HCCCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
METSKNHSIPIPFNEKERLDALHSYQIINTTPEEKFDSLTQIAAYICDSPIVLISLIDTN
CCCCCCCCCCCCCCCHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEECCC
RLWFKSKIGMNVSGIPRDISFCQYTIIQDEIFEIENALNDEKFQNNPFVLGPPYIRFYAG
CEEEEHCCCCCCCCCCCCCHHHEEEHHHHHHHHHHHHCCCCCCCCCCEEECCCCEEEEEC
TPLKTPEGFNVGTLCVFDTEPKRLDSRQKMTLKVLSNQIIANFELIKKNRELVSVHEKKE
CCCCCCCCCCCEEEEEECCCCHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
ELQKSKSQFFANMSHEIRTPVHGILGITSLLSETKLQPEQKEYVDIIRRNGNLLLSLLND
HHHHHHHHHHHHCHHHHHCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHH
ILDFSKLESSHMKIEIIAFDLMDLLKDVFYLFETDAKRKNLEFKMVGDTLSSLIVSTDPN
HHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHCCCCHH
RLKQILVNLISNAFKSTEKGSVSIEFEFDIKSDSKQCDIRIRVKDTGIGIPEQKLKELFQ
HHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCEEEEEEEEEECCCCCCHHHHHHHHH
AYSQMDTSVSRKYGGTGLGLAISKGLAEMMNLKLTAQSVINRGSVFEISGRIPLAERSEV
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCC
NFEPKKPNPDTNGASVQDLRILVAEDNEINQMLIKKVLEKLGYKPVIVSNGIEALHHIET
CCCCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHC
KGADVFFLDIQMPELSGIETAKILTQHTNQSIRPYIIAMTANASPEDKEDCLASGINEYI
CCCEEEEEEEECCCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHH
SKPFRKEEIADLLNHFIARKNSKT
HCCCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA