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The map label for this gene is gcvT [H]

Identifier: 116327162

GI number: 116327162

Start: 399780

End: 400895

Strand: Reverse

Name: gcvT [H]

Synonym: LBL_0340

Alternate gene names: 116327162

Gene position: 400895-399780 (Counterclockwise)

Preceding gene: 116327163

Following gene: 116327161

Centisome position: 11.09

GC content: 42.83

Gene sequence:

>1116_bases
ATGTCCCAAGTTAAGAGAACTCCACTTTATGAAACCCATCGCGCTCTAGGCGCTAAAATGATTCCCTTCGGGGGTTGGGA
TATGCCGGTTCAATATTCCGGAATTATCGCAGAGCATAACGCAACCAGAGAGGCCGCAGGACTTTTCGACGTTTCTCACA
TGGGAGAAATTTTTATAACGGGTGAACCGAAGATAGTTCTTGATTTTTTGGAATTGGTCACTTGCAACTCAGTCGCTTCT
CTTTCCGATTTTCAGGTTCAATATAACGCCATCTTGAATGAAAACGGCGGACTTGTGGACGACGTGACGATCTATAAATT
CTCCGCTGAAAAATACATGATCTGTTCCAACGCTTCCAACTACGAAACGGTGACCGCTCATTTACTCAAATATCTACCCG
CATCCGGCGTCAAAGTGAGCGACCAAAGTCCGAACTGGCATCAGATCGCTCTGCAAGGTCCGAAAGCAAATGAGATTTTC
TCTAAGTTCTTAGGTAGAGAATTGGATTCAATAAAATACTATCATTTCGCTCTTCTCGACTATCAAGGAGAAGAAATCAT
CGTCTCCAGAACAGGATACACCGGTGAGGACGGATTTGAAATTTATTCTTCCATTCCTTTCGGTTTAAAACTTTGGAGCG
GACTCTCAGAATTCGGGAAACCTCAGGGACTTCTTCCATGCGGGCTCGGCGCAAGAGATACTCTGCGAATTGAAGCAAAA
TATCCTCTTTACGGACACGAACTCAACAACCAATGGACTCCGATCGAATCGGGGATCGGTTGGATTGTGAAGGAAAAAAA
GAATCCTTATTTCTCATCCGGAAAAATTCTTTCTCAAAAGAAAAACGGAACCGAATTCAAAATTGTAGCGTTCGCATTAA
CGGAAGCGGGTGTTCCAAGAGAAAACTTCAGAGTTTTAGATTTTCAAGGAAATGAAATTGGTAAAACCACTTCCGGCACG
TTCTCTCCTTCTTTGAAAAAAGGAATCGGTTTGGCTTCCATTCGAACCGAAAAAATCAAAGACGGCGAACCGATTCAGAT
TGAAATTCGCGAGCAACCCAAACAAGCTATCATAACAACAAAGCCTTTTATTCCGGGCAGTATTAGAAAAAATTAA

Upstream 100 bases:

>100_bases
AATTCAGTATCTTCGATTTTCAGGTTAGAATCGAAAATTTTCCCAAAAAATCCATTTGTCCGAATACAAAACCCGTAAAA
ATTGGTACTCGGAAAGCTTT

Downstream 100 bases:

>100_bases
ATCAGGAAAAACGAATCATGGCAGAAACACAAGCTCCCGCAGGTTATCTCTTCTCGGAAAAACACGAATGGGTAAAAGTA
GAAGGGGACACAGCCCTTAT

Product: glycine cleavage system aminomethyltransferase T

Products: NA

Alternate protein names: Glycine cleavage system T protein [H]

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MSQVKRTPLYETHRALGAKMIPFGGWDMPVQYSGIIAEHNATREAAGLFDVSHMGEIFITGEPKIVLDFLELVTCNSVAS
LSDFQVQYNAILNENGGLVDDVTIYKFSAEKYMICSNASNYETVTAHLLKYLPASGVKVSDQSPNWHQIALQGPKANEIF
SKFLGRELDSIKYYHFALLDYQGEEIIVSRTGYTGEDGFEIYSSIPFGLKLWSGLSEFGKPQGLLPCGLGARDTLRIEAK
YPLYGHELNNQWTPIESGIGWIVKEKKNPYFSSGKILSQKKNGTEFKIVAFALTEAGVPRENFRVLDFQGNEIGKTTSGT
FSPSLKKGIGLASIRTEKIKDGEPIQIEIREQPKQAIITTKPFIPGSIRKN

Sequences:

>Translated_371_residues
MSQVKRTPLYETHRALGAKMIPFGGWDMPVQYSGIIAEHNATREAAGLFDVSHMGEIFITGEPKIVLDFLELVTCNSVAS
LSDFQVQYNAILNENGGLVDDVTIYKFSAEKYMICSNASNYETVTAHLLKYLPASGVKVSDQSPNWHQIALQGPKANEIF
SKFLGRELDSIKYYHFALLDYQGEEIIVSRTGYTGEDGFEIYSSIPFGLKLWSGLSEFGKPQGLLPCGLGARDTLRIEAK
YPLYGHELNNQWTPIESGIGWIVKEKKNPYFSSGKILSQKKNGTEFKIVAFALTEAGVPRENFRVLDFQGNEIGKTTSGT
FSPSLKKGIGLASIRTEKIKDGEPIQIEIREQPKQAIITTKPFIPGSIRKN
>Mature_370_residues
SQVKRTPLYETHRALGAKMIPFGGWDMPVQYSGIIAEHNATREAAGLFDVSHMGEIFITGEPKIVLDFLELVTCNSVASL
SDFQVQYNAILNENGGLVDDVTIYKFSAEKYMICSNASNYETVTAHLLKYLPASGVKVSDQSPNWHQIALQGPKANEIFS
KFLGRELDSIKYYHFALLDYQGEEIIVSRTGYTGEDGFEIYSSIPFGLKLWSGLSEFGKPQGLLPCGLGARDTLRIEAKY
PLYGHELNNQWTPIESGIGWIVKEKKNPYFSSGKILSQKKNGTEFKIVAFALTEAGVPRENFRVLDFQGNEIGKTTSGTF
SPSLKKGIGLASIRTEKIKDGEPIQIEIREQPKQAIITTKPFIPGSIRKN

Specific function: The glycine cleavage system catalyzes the degradation of glycine [H]

COG id: COG0404

COG function: function code E; Glycine cleavage system T protein (aminomethyltransferase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family [H]

Homologues:

Organism=Homo sapiens, GI44662838, Length=369, Percent_Identity=31.1653116531165, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI257796258, Length=357, Percent_Identity=31.0924369747899, Blast_Score=172, Evalue=4e-43,
Organism=Homo sapiens, GI257796254, Length=366, Percent_Identity=28.9617486338798, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI257796256, Length=305, Percent_Identity=27.8688524590164, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI24797151, Length=337, Percent_Identity=22.2551928783383, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI194306651, Length=375, Percent_Identity=23.7333333333333, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI197927446, Length=340, Percent_Identity=22.3529411764706, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI21361378, Length=340, Percent_Identity=22.3529411764706, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI1789272, Length=368, Percent_Identity=35.5978260869565, Blast_Score=202, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17560118, Length=378, Percent_Identity=30.1587301587302, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI71994045, Length=348, Percent_Identity=22.7011494252874, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71994052, Length=348, Percent_Identity=22.7011494252874, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI32563613, Length=245, Percent_Identity=23.6734693877551, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320222, Length=392, Percent_Identity=33.4183673469388, Blast_Score=165, Evalue=1e-41,
Organism=Drosophila melanogaster, GI20129441, Length=375, Percent_Identity=31.7333333333333, Blast_Score=164, Evalue=8e-41,
Organism=Drosophila melanogaster, GI28571104, Length=274, Percent_Identity=24.4525547445255, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006223
- InterPro:   IPR022903 [H]

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C [H]

EC number: =2.1.2.10 [H]

Molecular weight: Translated: 41235; Mature: 41103

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQVKRTPLYETHRALGAKMIPFGGWDMPVQYSGIIAEHNATREAAGLFDVSHMGEIFIT
CCCCCCCCCHHHHHHHCCEECCCCCCCCCEEECCEEEECCCCHHHHCEEECCCCCCEEEE
GEPKIVLDFLELVTCNSVASLSDFQVQYNAILNENGGLVDDVTIYKFSAEKYMICSNASN
CCCHHHHHHHHHHHCCCCCCCCHHEEEEEEEECCCCCEEEEEEEEEECCCEEEEECCCCC
YETVTAHLLKYLPASGVKVSDQSPNWHQIALQGPKANEIFSKFLGRELDSIKYYHFALLD
CHHHHHHHHHHCCCCCEEECCCCCCEEEEEEECCCHHHHHHHHHCCHHHCCEEEEEEEEE
YQGEEIIVSRTGYTGEDGFEIYSSIPFGLKLWSGLSEFGKPQGLLPCGLGARDTLRIEAK
ECCCEEEEEECCCCCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCEECCCCCCCEEEEEEE
YPLYGHELNNQWTPIESGIGWIVKEKKNPYFSSGKILSQKKNGTEFKIVAFALTEAGVPR
CCCCCCCCCCCCCCHHCCCEEEEEECCCCCCCCCCEEECCCCCCEEEEEEEEEECCCCCC
ENFRVLDFQGNEIGKTTSGTFSPSLKKGIGLASIRTEKIKDGEPIQIEIREQPKQAIITT
CCCEEEEECCCCCCCCCCCCCCCHHHHCCCEEEEEHHHCCCCCCEEEEECCCCCEEEEEE
KPFIPGSIRKN
CCCCCCCCCCC
>Mature Secondary Structure 
SQVKRTPLYETHRALGAKMIPFGGWDMPVQYSGIIAEHNATREAAGLFDVSHMGEIFIT
CCCCCCCCHHHHHHHCCEECCCCCCCCCEEECCEEEECCCCHHHHCEEECCCCCCEEEE
GEPKIVLDFLELVTCNSVASLSDFQVQYNAILNENGGLVDDVTIYKFSAEKYMICSNASN
CCCHHHHHHHHHHHCCCCCCCCHHEEEEEEEECCCCCEEEEEEEEEECCCEEEEECCCCC
YETVTAHLLKYLPASGVKVSDQSPNWHQIALQGPKANEIFSKFLGRELDSIKYYHFALLD
CHHHHHHHHHHCCCCCEEECCCCCCEEEEEEECCCHHHHHHHHHCCHHHCCEEEEEEEEE
YQGEEIIVSRTGYTGEDGFEIYSSIPFGLKLWSGLSEFGKPQGLLPCGLGARDTLRIEAK
ECCCEEEEEECCCCCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCEECCCCCCCEEEEEEE
YPLYGHELNNQWTPIESGIGWIVKEKKNPYFSSGKILSQKKNGTEFKIVAFALTEAGVPR
CCCCCCCCCCCCCCHHCCCEEEEEECCCCCCCCCCEEECCCCCCEEEEEEEEEECCCCCC
ENFRVLDFQGNEIGKTTSGTFSPSLKKGIGLASIRTEKIKDGEPIQIEIREQPKQAIITT
CCCEEEEECCCCCCCCCCCCCCCHHHHCCCEEEEEHHHCCCCCCEEEEECCCCCEEEEEE
KPFIPGSIRKN
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA