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The map label for this gene is yggV [C]

Identifier: 116327023

GI number: 116327023

Start: 229678

End: 230268

Strand: Direct

Name: yggV [C]

Synonym: LBL_0196

Alternate gene names: 116327023

Gene position: 229678-230268 (Clockwise)

Preceding gene: 116327022

Following gene: 116327025

Centisome position: 6.35

GC content: 40.78

Gene sequence:

>591_bases
TTGAAACGAATCGTTCTTGCCACAAACAATCGGTACAAAGTAAAGGAAGTCGGTTTTATTCTTTCCGAGTTAGGAATTCA
GGTCCTTACTCCTAATGATTTGAGGATTTCTTTTAACGCAGAAGAGACCGGTTCTACATTTGCAGAAAATGCTTTCATTA
AAGCGAGAGAGTTGTTTCGTTTGACGAAACTTCCTTCCATCGCGGACGATTCCGGAATCTGTGTCTCTGCGCTTGGAGGA
GAACCGGGGGTTTATTCCGCGAGATTCGGAGGTCCTGGGTTAAAAGACGAGGATCGTGCCCTTTTCCTTTTAGAAAAAAT
GAAAGAAAACTCGGACCGTAGAGCACATTACACTTGTGTTATCACCTACGTGGACGAAACCTCCGAACAAAGTTTTGAAG
GCAGATGTGAGGGAACCATTTCGGAAGAATATGATAGAATTGGAATGTATGGCTTTGGATATGATCCTATTTTTATTTAT
CCCCCTTTTCAAAAGCCTTTTTCACAGGTTCCAGAAGCGGAAAAAAATTCGGTTTCCCATAGAAAAAAGGCTTTGGAACA
ATTCTTAAAATTCTTAAAAACGAAATCGTAG

Upstream 100 bases:

>100_bases
TTGCAGCTTTTTGAGATCACGATGTTGGATAAGGTTTTTAAAATAGTTCCTAATATCGAAGACGCGTTCGACGAATTTAA
GTTGAATCGCTGATCTCTTT

Downstream 100 bases:

>100_bases
AAATATCTTTCATAACTTGTCCAAAAGATTTGGAATCTGCCCCAAAACCTCGGATGTAGGAACTCCTACGAGAGTGTTCC
AACGATAAAATCCGTTAGAA

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MKRIVLATNNRYKVKEVGFILSELGIQVLTPNDLRISFNAEETGSTFAENAFIKARELFRLTKLPSIADDSGICVSALGG
EPGVYSARFGGPGLKDEDRALFLLEKMKENSDRRAHYTCVITYVDETSEQSFEGRCEGTISEEYDRIGMYGFGYDPIFIY
PPFQKPFSQVPEAEKNSVSHRKKALEQFLKFLKTKS

Sequences:

>Translated_196_residues
MKRIVLATNNRYKVKEVGFILSELGIQVLTPNDLRISFNAEETGSTFAENAFIKARELFRLTKLPSIADDSGICVSALGG
EPGVYSARFGGPGLKDEDRALFLLEKMKENSDRRAHYTCVITYVDETSEQSFEGRCEGTISEEYDRIGMYGFGYDPIFIY
PPFQKPFSQVPEAEKNSVSHRKKALEQFLKFLKTKS
>Mature_196_residues
MKRIVLATNNRYKVKEVGFILSELGIQVLTPNDLRISFNAEETGSTFAENAFIKARELFRLTKLPSIADDSGICVSALGG
EPGVYSARFGGPGLKDEDRALFLLEKMKENSDRRAHYTCVITYVDETSEQSFEGRCEGTISEEYDRIGMYGFGYDPIFIY
PPFQKPFSQVPEAEKNSVSHRKKALEQFLKFLKTKS

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=198, Percent_Identity=29.7979797979798, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1789324, Length=198, Percent_Identity=41.9191919191919, Blast_Score=152, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17556833, Length=196, Percent_Identity=28.0612244897959, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19920712, Length=186, Percent_Identity=29.5698924731183, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 22146; Mature: 22146

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRIVLATNNRYKVKEVGFILSELGIQVLTPNDLRISFNAEETGSTFAENAFIKARELFR
CCEEEEECCCCEEHHHHHHHHHHCCEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHH
LTKLPSIADDSGICVSALGGEPGVYSARFGGPGLKDEDRALFLLEKMKENSDRRAHYTCV
HHCCCCCCCCCCCEEEECCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEE
ITYVDETSEQSFEGRCEGTISEEYDRIGMYGFGYDPIFIYPPFQKPFSQVPEAEKNSVSH
EEEECCCCCCCCCCCCCCCCHHHHHHCCEEECCCCCEEEECCCCCHHHHCCCCHHHHHHH
RKKALEQFLKFLKTKS
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKRIVLATNNRYKVKEVGFILSELGIQVLTPNDLRISFNAEETGSTFAENAFIKARELFR
CCEEEEECCCCEEHHHHHHHHHHCCEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHH
LTKLPSIADDSGICVSALGGEPGVYSARFGGPGLKDEDRALFLLEKMKENSDRRAHYTCV
HHCCCCCCCCCCCEEEECCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEE
ITYVDETSEQSFEGRCEGTISEEYDRIGMYGFGYDPIFIYPPFQKPFSQVPEAEKNSVSH
EEEECCCCCCCCCCCCCCCCHHHHHHCCEEECCCCCEEEECCCCCHHHHCCCCHHHHHHH
RKKALEQFLKFLKTKS
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA