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The map label for this gene is tpn50 [H]

Identifier: 116327025

GI number: 116327025

Start: 232446

End: 234449

Strand: Direct

Name: tpn50 [H]

Synonym: LBL_0198

Alternate gene names: 116327025

Gene position: 232446-234449 (Clockwise)

Preceding gene: 116327023

Following gene: 116327027

Centisome position: 6.43

GC content: 38.72

Gene sequence:

>2004_bases
ATGCGTTCTAAACTTCAAGTAATGCTGATTTTATCGATCTTGGGTTTTCTTTCTTTCACAGATCTTAAGGCCAAGGATTC
CTTAAAGAAACTCGATGACGCAACTTCTTGGATCCCGGTTCGTAAACAAAATTCCATTCAATTCGCATCGCAACAGGAGA
AACTGAAAAACACAACGGCAAACTTTTCCGACCGAGAAACACCAAACACGGAAAGCGGCTATAAGTTATTGATAGGAAAG
ATTCTTCAATTCGGAAAATTGCTTAGTACGGAAAACGCATATATTTCAATCGAGTCTAATGAAATTACTTCAGAACTTTC
CAAACTCAATGATAAAACCGTAAGAATCCTTTGCAGTATGAGAGGATCCACTTGCAATCCGATTCGTTACGAAATCTATC
CGTTTCTCAACTCGAAAGAGATTGAACCTTGGGCGATTAAAAAAATTCCAGATTACGTAAATCATAATATTTTTGCATTC
AATCCGACCGTTTCTCCGGACGGAAAATATCTTTTTTGGACCGCGTATATCAAACAGGGCAAATCGGGAACTCAGAAGAT
CTGGTATTCAAAACTAGACGAAAAAGGATTTTGGGAAGATGGAAAAGAAATGAACGCGCCTTTGAACAATGAGATGCCTT
CCGCCGTCATTTCCGCATTGCCGGGGGGAAACGAACTTTTCGTTTTCGGAACCTTCGGCGAAAAAGAACTTTTAGACGAA
CTCGGAAAAGATTTCGAAGCAAAGGGAGAATTGGCGGCGCGTTCCTCCAAGAATTCCAACGAATACAGAAAAAAGATCGA
GGAACTTAGAGCCGAATACGACGAAAAAACGAAGCAGATCACAAGAAGAGTTCCTCTCTATAAAAGTTTTAAAGAAAAAG
ATTCCTGGTCTAAGCCAAGTATATTAAAGTTTCCTGATTTTTATAATCTCTACAGAAAGAAAAACGATTCAAGCCAGGAA
ATTTTCGGAGGCTCTACTCTTTCTTCTTCGGGAAAAATTTTGATTTATTCCTCCCAACATAAGGACTCCAAAGGGAAATT
AGACCTTTATGTGAGTAAGATGTCAAGCGACGGAACTTTTCCTTTGGGAACAAATTTAGGCGAAGTTGTCAATACTGATC
ACGAAGAGATGGCTCCGTTTTTAGCAAGCGATGATAGAACTCTTTATTTTTCCAGCGACGGACGAAAAGGGATTTCCATT
TATATGACGAAAAGAATCGGAGACGGTTGGGATCAATGGACTAAACCGACCGAAGTTTCGGAGAATCTGAAAGGTGTGAA
TTTTTTTTCGATTCCTGCAAATAGCGACTGGGCTTACATCAGTAAAAACGGTCAGTTGTTTATGGCTTATCTTCCGAAGG
AAATGCGTCCCGAAAAAGTAGTAGTTGTAAATGGAAAGGTGACGGACACCGAAGGAAATCCTCTTCCTGCCGATATACAT
TATGAATCTTTAAAGTCTCACGAGAAAATTGGAAGCACAAAAAGTGATCCTTCCACCGGAAATTTTTCCATCATCCTTCC
TTTCGGAGAAAATTACGGCTTTTATGCTCAGAAGAAGGGGTATCTTCCTGTATCACAAAATTTGAATTTAAATTCCAAAA
AGAATTTCTCTGAAAAAGTGGAGGTTCTTTTGCAACTTCCTCGGATTGAAGAACGCGGAACAATTCAAATTAATAATTTG
TTTTTCGAATCCAAAAGTTTTCGAATCATTCCTGAATCGGAGCCGGAACTTAATCGTCTTGCCGAGATTATGAAAGAAAA
TCCGGATATTAAAATTCAAATCGAAGGACATACGGACAACGTTGGAAAGAAAAAGGATAATCTTCTTCTTTCCGAAAAAC
GTGCGATAGCGATTGCCGAATATCTTTCTCAAAAACATTCAATTCCTACTGAAAGAATTAAAACCCGAGGTTTCGGAGAC
AACTTTCCTTTGAGTAAGAACGACTCCGAAGAAGGACGTAGAAAAAATAGAAGAGTAAATTTTACCATTCTCAAAAGCAA
ATGA

Upstream 100 bases:

>100_bases
CTGCTAGGGAAGAATCATGACCATGATTTTCAAAATAGGGTTTTTTGCCAAGAAAAAGTAGAATTAAGGACTTTCGAAAT
TTTACCGAAATTAAAAACGT

Downstream 100 bases:

>100_bases
GAATACGGTAGAGACATCTTTATAAAATCAAAAAACAACAGAACGTTATAAAAAATCCCTATACGAAACCGCTGTTTTGC
CACGTTCAAGAATTCTAAAA

Product: OmpA-family protein

Products: NA

Alternate protein names: Antigen tpp57 [H]

Number of amino acids: Translated: 667; Mature: 667

Protein sequence:

>667_residues
MRSKLQVMLILSILGFLSFTDLKAKDSLKKLDDATSWIPVRKQNSIQFASQQEKLKNTTANFSDRETPNTESGYKLLIGK
ILQFGKLLSTENAYISIESNEITSELSKLNDKTVRILCSMRGSTCNPIRYEIYPFLNSKEIEPWAIKKIPDYVNHNIFAF
NPTVSPDGKYLFWTAYIKQGKSGTQKIWYSKLDEKGFWEDGKEMNAPLNNEMPSAVISALPGGNELFVFGTFGEKELLDE
LGKDFEAKGELAARSSKNSNEYRKKIEELRAEYDEKTKQITRRVPLYKSFKEKDSWSKPSILKFPDFYNLYRKKNDSSQE
IFGGSTLSSSGKILIYSSQHKDSKGKLDLYVSKMSSDGTFPLGTNLGEVVNTDHEEMAPFLASDDRTLYFSSDGRKGISI
YMTKRIGDGWDQWTKPTEVSENLKGVNFFSIPANSDWAYISKNGQLFMAYLPKEMRPEKVVVVNGKVTDTEGNPLPADIH
YESLKSHEKIGSTKSDPSTGNFSIILPFGENYGFYAQKKGYLPVSQNLNLNSKKNFSEKVEVLLQLPRIEERGTIQINNL
FFESKSFRIIPESEPELNRLAEIMKENPDIKIQIEGHTDNVGKKKDNLLLSEKRAIAIAEYLSQKHSIPTERIKTRGFGD
NFPLSKNDSEEGRRKNRRVNFTILKSK

Sequences:

>Translated_667_residues
MRSKLQVMLILSILGFLSFTDLKAKDSLKKLDDATSWIPVRKQNSIQFASQQEKLKNTTANFSDRETPNTESGYKLLIGK
ILQFGKLLSTENAYISIESNEITSELSKLNDKTVRILCSMRGSTCNPIRYEIYPFLNSKEIEPWAIKKIPDYVNHNIFAF
NPTVSPDGKYLFWTAYIKQGKSGTQKIWYSKLDEKGFWEDGKEMNAPLNNEMPSAVISALPGGNELFVFGTFGEKELLDE
LGKDFEAKGELAARSSKNSNEYRKKIEELRAEYDEKTKQITRRVPLYKSFKEKDSWSKPSILKFPDFYNLYRKKNDSSQE
IFGGSTLSSSGKILIYSSQHKDSKGKLDLYVSKMSSDGTFPLGTNLGEVVNTDHEEMAPFLASDDRTLYFSSDGRKGISI
YMTKRIGDGWDQWTKPTEVSENLKGVNFFSIPANSDWAYISKNGQLFMAYLPKEMRPEKVVVVNGKVTDTEGNPLPADIH
YESLKSHEKIGSTKSDPSTGNFSIILPFGENYGFYAQKKGYLPVSQNLNLNSKKNFSEKVEVLLQLPRIEERGTIQINNL
FFESKSFRIIPESEPELNRLAEIMKENPDIKIQIEGHTDNVGKKKDNLLLSEKRAIAIAEYLSQKHSIPTERIKTRGFGD
NFPLSKNDSEEGRRKNRRVNFTILKSK
>Mature_667_residues
MRSKLQVMLILSILGFLSFTDLKAKDSLKKLDDATSWIPVRKQNSIQFASQQEKLKNTTANFSDRETPNTESGYKLLIGK
ILQFGKLLSTENAYISIESNEITSELSKLNDKTVRILCSMRGSTCNPIRYEIYPFLNSKEIEPWAIKKIPDYVNHNIFAF
NPTVSPDGKYLFWTAYIKQGKSGTQKIWYSKLDEKGFWEDGKEMNAPLNNEMPSAVISALPGGNELFVFGTFGEKELLDE
LGKDFEAKGELAARSSKNSNEYRKKIEELRAEYDEKTKQITRRVPLYKSFKEKDSWSKPSILKFPDFYNLYRKKNDSSQE
IFGGSTLSSSGKILIYSSQHKDSKGKLDLYVSKMSSDGTFPLGTNLGEVVNTDHEEMAPFLASDDRTLYFSSDGRKGISI
YMTKRIGDGWDQWTKPTEVSENLKGVNFFSIPANSDWAYISKNGQLFMAYLPKEMRPEKVVVVNGKVTDTEGNPLPADIH
YESLKSHEKIGSTKSDPSTGNFSIILPFGENYGFYAQKKGYLPVSQNLNLNSKKNFSEKVEVLLQLPRIEERGTIQINNL
FFESKSFRIIPESEPELNRLAEIMKENPDIKIQIEGHTDNVGKKKDNLLLSEKRAIAIAEYLSQKHSIPTERIKTRGFGD
NFPLSKNDSEEGRRKNRRVNFTILKSK

Specific function: Could function as a porin [H]

COG id: COG2885

COG function: function code M; Outer membrane protein and related peptidoglycan-associated (lipo)proteins

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 OmpA-like domain [H]

Homologues:

Organism=Escherichia coli, GI48994946, Length=106, Percent_Identity=33.9622641509434, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788957, Length=104, Percent_Identity=30.7692307692308, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006664
- InterPro:   IPR006690
- InterPro:   IPR006665 [H]

Pfam domain/function: PF00691 OmpA [H]

EC number: NA

Molecular weight: Translated: 75937; Mature: 75937

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS01068 OMPA_1 ; PS51123 OMPA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSKLQVMLILSILGFLSFTDLKAKDSLKKLDDATSWIPVRKQNSIQFASQQEKLKNTTA
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCC
NFSDRETPNTESGYKLLIGKILQFGKLLSTENAYISIESNEITSELSKLNDKTVRILCSM
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHCCCCEEEEEEEC
RGSTCNPIRYEIYPFLNSKEIEPWAIKKIPDYVNHNIFAFNPTVSPDGKYLFWTAYIKQG
CCCCCCCEEEEEEECCCCCCCCCCHHHCCHHHHCCCEEEECCCCCCCCCEEEEEEEECCC
KSGTQKIWYSKLDEKGFWEDGKEMNAPLNNEMPSAVISALPGGNELFVFGTFGEKELLDE
CCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEECCCCHHHHHH
LGKDFEAKGELAARSSKNSNEYRKKIEELRAEYDEKTKQITRRVPLYKSFKEKDSWSKPS
HCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCC
ILKFPDFYNLYRKKNDSSQEIFGGSTLSSSGKILIYSSQHKDSKGKLDLYVSKMSSDGTF
EEECCHHHHHHHCCCCCCCCCCCCCEECCCCCEEEEECCCCCCCCCEEEEEEEECCCCCC
PLGTNLGEVVNTDHEEMAPFLASDDRTLYFSSDGRKGISIYMTKRIGDGWDQWTKPTEVS
CCCCCCHHHHCCCHHHHCCHHCCCCCEEEECCCCCCCEEEEEEECCCCCHHHCCCCCHHH
ENLKGVNFFSIPANSDWAYISKNGQLFMAYLPKEMRPEKVVVVNGKVTDTEGNPLPADIH
HCCCCCEEEECCCCCCEEEEECCCCEEEEECCCCCCCCEEEEECCEEECCCCCCCCCCCC
YESLKSHEKIGSTKSDPSTGNFSIILPFGENYGFYAQKKGYLPVSQNLNLNSKKNFSEKV
HHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHH
EVLLQLPRIEERGTIQINNLFFESKSFRIIPESEPELNRLAEIMKENPDIKIQIEGHTDN
HHHHHCCCCCCCCCEEEEEEEEECCCEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCC
VGKKKDNLLLSEKRAIAIAEYLSQKHSIPTERIKTRGFGDNFPLSKNDSEEGRRKNRRVN
CCCCCCCEEEHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHCCEEE
FTILKSK
EEEEECC
>Mature Secondary Structure
MRSKLQVMLILSILGFLSFTDLKAKDSLKKLDDATSWIPVRKQNSIQFASQQEKLKNTTA
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCC
NFSDRETPNTESGYKLLIGKILQFGKLLSTENAYISIESNEITSELSKLNDKTVRILCSM
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHCCCCEEEEEEEC
RGSTCNPIRYEIYPFLNSKEIEPWAIKKIPDYVNHNIFAFNPTVSPDGKYLFWTAYIKQG
CCCCCCCEEEEEEECCCCCCCCCCHHHCCHHHHCCCEEEECCCCCCCCCEEEEEEEECCC
KSGTQKIWYSKLDEKGFWEDGKEMNAPLNNEMPSAVISALPGGNELFVFGTFGEKELLDE
CCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEECCCCHHHHHH
LGKDFEAKGELAARSSKNSNEYRKKIEELRAEYDEKTKQITRRVPLYKSFKEKDSWSKPS
HCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCC
ILKFPDFYNLYRKKNDSSQEIFGGSTLSSSGKILIYSSQHKDSKGKLDLYVSKMSSDGTF
EEECCHHHHHHHCCCCCCCCCCCCCEECCCCCEEEEECCCCCCCCCEEEEEEEECCCCCC
PLGTNLGEVVNTDHEEMAPFLASDDRTLYFSSDGRKGISIYMTKRIGDGWDQWTKPTEVS
CCCCCCHHHHCCCHHHHCCHHCCCCCEEEECCCCCCCEEEEEEECCCCCHHHCCCCCHHH
ENLKGVNFFSIPANSDWAYISKNGQLFMAYLPKEMRPEKVVVVNGKVTDTEGNPLPADIH
HCCCCCEEEECCCCCCEEEEECCCCEEEEECCCCCCCCEEEEECCEEECCCCCCCCCCCC
YESLKSHEKIGSTKSDPSTGNFSIILPFGENYGFYAQKKGYLPVSQNLNLNSKKNFSEKV
HHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHH
EVLLQLPRIEERGTIQINNLFFESKSFRIIPESEPELNRLAEIMKENPDIKIQIEGHTDN
HHHHHCCCCCCCCCEEEEEEEEECCCEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCC
VGKKKDNLLLSEKRAIAIAEYLSQKHSIPTERIKTRGFGDNFPLSKNDSEEGRRKNRRVN
CCCCCCCEEEHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHCCEEE
FTILKSK
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8112835; 7623668; 9665876 [H]