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The map label for this gene is pabB [H]

Identifier: 116326892

GI number: 116326892

Start: 54967

End: 56742

Strand: Direct

Name: pabB [H]

Synonym: LBL_0046

Alternate gene names: 116326892

Gene position: 54967-56742 (Clockwise)

Preceding gene: 116326890

Following gene: 116326893

Centisome position: 1.52

GC content: 36.94

Gene sequence:

>1776_bases
ATGATAATCGAAGAACTCATATTCTCTGGCCAGCCCTTTATGATTTTCGACGAAGGATTCCATCCTTTCGGAAAAATTAT
CTTCCGCAATCCCATTAAAACGATCGAGGCGTATTGTTTCGATACATTGTCAACTTCTTTGAACGAAATAAACGATTGTT
TAAAACAAGGGTATTACGTAGCGGGTTTTATTTCTTATGAAGTAGGTTATTTTTTCTTCAATATGAATTGGAAAAAAACC
GAGACAGGTTTACCAATTTTATATTTTGCAGTTTTCCAAAAACCCGAAAAGCTCGCGGAAATTCAAACGGAACTTTCACA
AAATTACGGCTTTTATATTTCTTCGATGCCGAATCATGAGAATTATATTCAAAGTTTGGATACCATCCGAACTAAACTTT
ATCAAGGAGAAATTTATCAGATCAATTATACGGACAAAATTTTTTTCGATTTCGAAGGAGATACATTATCATTTTATAAA
ATACTATCCCAAAGGCAACCGGTTGCTTACGGTTCCTGGATTCGATTCCGCGATATAGATATACTTTCCTTCTCACCGGA
ACTTTTCTTTGAGAAAAAAGGAACAACGCTCGTTACCAAACCGATGAAAGGAACGTATCAAAGAGGTAAATCCGAAAAAG
AAGATGAGAAAAACATTCAAATTCTTCTGAATTCCGAAAAAGAAAAAGCGGAAAATCTGATGATTACGGATTTGATGCGG
AACGATCTTGGGAAAATCAGTAAAAAAGGAAGTGTTCAAGTTCCAGCCTTGTTTTCCATAGAAAAGTACAAAACGATCCT
TCAAATGACGAGTACGATTCGATCCGAACTCTCAGATTGGGTCGAATGGAAGGATATTTTCAGAGAACTTTTTCCGGGTG
GATCCATTACCGGCGCTCCGAAATTTAGAGCAATGCAATTGATCCAACAATTGGAAAAGTCAAGAGGAATTTATACAGGC
GCGATCGGAGTCATTGAACCCGATCAAAACGCGGTTTTTTCGATCGGAATCCGAACTTTGGAATTAAAAAAGGGAAAAGG
GAATATCGGAATCGGTTCCGGAATCACGTGGGATTCCGATCCCGAAAAAGAATGGCTTGAAATTCTAGAAAAAGCGAAAT
TTTTCACAGAAGCGCCGCAAGGATTTTTCCTTTTCGAAACAATACTTTACAAAAATGGAATATTCTACTTTCTAAAAGAA
CATCTGGAAAGAATCAAAAAATCCGCCGAGATTTTTCAATTCCCCTTCTCAAAAAAAGAATGGGACACTTCTCTGAAACA
AATTGCCTCAATTTCTCCCGGCCCGAGCTCATACCGAATCAAAATCAGCCTAAATCCTCTTGGAAAATTTCATTTCGAGT
CGCACAAACTCTCAAAATTTCAGAAAGAAGGTATTTTACAAATCAGTGAAATTGAAATCGATTCTTCCTCGGAGTTTAGA
AAGCATAAAACAAATTTGAGGGAAATATACGATCGAGAAGGAAAACGTTCCAGAGACGCAGGTTATATCGACACTTTATA
CTTAAACGAAAAAAAGGAAATCACCGAAGGAAGTATCAGTAATATATTCGTAAAAATCGGAGATTCGTATTTTACTCCTC
CGATTTCTTCAGGAGTTCTTCCCGGCGTTTTTCGAAATCGCCTTTTAAAACGAAACGGGTTTTACGAGAAAACTCTTTGT
TTGGACGACTTACAACGATCAAACTCGATATTTCTATGTAACTCTCTCCGAGGAATCTTGAGAGTGAAAGAAGTTCACAA
ACCTAAAAAAGAATAA

Upstream 100 bases:

>100_bases
AAAAGTAATAGATAAACCCGGAAATAAAAACAATTCCCGAGGTTCTTATAATTCTTTTGAAACGAAGAGACAAAATCATT
AATCCAATTAAGTTTGTTTT

Downstream 100 bases:

>100_bases
CGTAGAAATCTAGTTGCGAAAATCAAAAAGAGTCCTAAACTTTCAAACATGAGAACTTTTCTTGGAATCTCAATTCCGGA
AGAAGTGGAAGAACAACTAA

Product: Para-aminobenzoate synthase

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 591; Mature: 591

Protein sequence:

>591_residues
MIIEELIFSGQPFMIFDEGFHPFGKIIFRNPIKTIEAYCFDTLSTSLNEINDCLKQGYYVAGFISYEVGYFFFNMNWKKT
ETGLPILYFAVFQKPEKLAEIQTELSQNYGFYISSMPNHENYIQSLDTIRTKLYQGEIYQINYTDKIFFDFEGDTLSFYK
ILSQRQPVAYGSWIRFRDIDILSFSPELFFEKKGTTLVTKPMKGTYQRGKSEKEDEKNIQILLNSEKEKAENLMITDLMR
NDLGKISKKGSVQVPALFSIEKYKTILQMTSTIRSELSDWVEWKDIFRELFPGGSITGAPKFRAMQLIQQLEKSRGIYTG
AIGVIEPDQNAVFSIGIRTLELKKGKGNIGIGSGITWDSDPEKEWLEILEKAKFFTEAPQGFFLFETILYKNGIFYFLKE
HLERIKKSAEIFQFPFSKKEWDTSLKQIASISPGPSSYRIKISLNPLGKFHFESHKLSKFQKEGILQISEIEIDSSSEFR
KHKTNLREIYDREGKRSRDAGYIDTLYLNEKKEITEGSISNIFVKIGDSYFTPPISSGVLPGVFRNRLLKRNGFYEKTLC
LDDLQRSNSIFLCNSLRGILRVKEVHKPKKE

Sequences:

>Translated_591_residues
MIIEELIFSGQPFMIFDEGFHPFGKIIFRNPIKTIEAYCFDTLSTSLNEINDCLKQGYYVAGFISYEVGYFFFNMNWKKT
ETGLPILYFAVFQKPEKLAEIQTELSQNYGFYISSMPNHENYIQSLDTIRTKLYQGEIYQINYTDKIFFDFEGDTLSFYK
ILSQRQPVAYGSWIRFRDIDILSFSPELFFEKKGTTLVTKPMKGTYQRGKSEKEDEKNIQILLNSEKEKAENLMITDLMR
NDLGKISKKGSVQVPALFSIEKYKTILQMTSTIRSELSDWVEWKDIFRELFPGGSITGAPKFRAMQLIQQLEKSRGIYTG
AIGVIEPDQNAVFSIGIRTLELKKGKGNIGIGSGITWDSDPEKEWLEILEKAKFFTEAPQGFFLFETILYKNGIFYFLKE
HLERIKKSAEIFQFPFSKKEWDTSLKQIASISPGPSSYRIKISLNPLGKFHFESHKLSKFQKEGILQISEIEIDSSSEFR
KHKTNLREIYDREGKRSRDAGYIDTLYLNEKKEITEGSISNIFVKIGDSYFTPPISSGVLPGVFRNRLLKRNGFYEKTLC
LDDLQRSNSIFLCNSLRGILRVKEVHKPKKE
>Mature_591_residues
MIIEELIFSGQPFMIFDEGFHPFGKIIFRNPIKTIEAYCFDTLSTSLNEINDCLKQGYYVAGFISYEVGYFFFNMNWKKT
ETGLPILYFAVFQKPEKLAEIQTELSQNYGFYISSMPNHENYIQSLDTIRTKLYQGEIYQINYTDKIFFDFEGDTLSFYK
ILSQRQPVAYGSWIRFRDIDILSFSPELFFEKKGTTLVTKPMKGTYQRGKSEKEDEKNIQILLNSEKEKAENLMITDLMR
NDLGKISKKGSVQVPALFSIEKYKTILQMTSTIRSELSDWVEWKDIFRELFPGGSITGAPKFRAMQLIQQLEKSRGIYTG
AIGVIEPDQNAVFSIGIRTLELKKGKGNIGIGSGITWDSDPEKEWLEILEKAKFFTEAPQGFFLFETILYKNGIFYFLKE
HLERIKKSAEIFQFPFSKKEWDTSLKQIASISPGPSSYRIKISLNPLGKFHFESHKLSKFQKEGILQISEIEIDSSSEFR
KHKTNLREIYDREGKRSRDAGYIDTLYLNEKKEITEGSISNIFVKIGDSYFTPPISSGVLPGVFRNRLLKRNGFYEKTLC
LDDLQRSNSIFLCNSLRGILRVKEVHKPKKE

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=253, Percent_Identity=38.3399209486166, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI1787518, Length=259, Percent_Identity=28.1853281853282, Blast_Score=116, Evalue=5e-27,
Organism=Escherichia coli, GI1786809, Length=223, Percent_Identity=25.5605381165919, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI87082077, Length=192, Percent_Identity=24.4791666666667, Blast_Score=69, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6320935, Length=329, Percent_Identity=29.7872340425532, Blast_Score=139, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6324361, Length=272, Percent_Identity=27.9411764705882, Blast_Score=105, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 68495; Mature: 68495

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIEELIFSGQPFMIFDEGFHPFGKIIFRNPIKTIEAYCFDTLSTSLNEINDCLKQGYYV
CCHHHHHHCCCCEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
AGFISYEVGYFFFNMNWKKTETGLPILYFAVFQKPEKLAEIQTELSQNYGFYISSMPNHE
EEEEEEEEEEEEEECCCEECCCCCCEEEHHHHCCHHHHHHHHHHHHCCCCEEEECCCCHH
NYIQSLDTIRTKLYQGEIYQINYTDKIFFDFEGDTLSFYKILSQRQPVAYGSWIRFRDID
HHHHHHHHHHHHHHCCCEEEEECCEEEEEEECCCCHHHHHHHHCCCCCCCCCEEEEEEEE
ILSFSPELFFEKKGTTLVTKPMKGTYQRGKSEKEDEKNIQILLNSEKEKAENLMITDLMR
EEEECCHHEEECCCCEEEECCCCCHHHCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHH
NDLGKISKKGSVQVPALFSIEKYKTILQMTSTIRSELSDWVEWKDIFRELFPGGSITGAP
HHHHHHCCCCCEECCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
KFRAMQLIQQLEKSRGIYTGAIGVIEPDQNAVFSIGIRTLELKKGKGNIGIGSGITWDSD
HHHHHHHHHHHHHHCCEEEEEEEEEECCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCC
PEKEWLEILEKAKFFTEAPQGFFLFETILYKNGIFYFLKEHLERIKKSAEIFQFPFSKKE
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHH
WDTSLKQIASISPGPSSYRIKISLNPLGKFHFESHKLSKFQKEGILQISEIEIDSSSEFR
HHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEEEECCCHHHH
KHKTNLREIYDREGKRSRDAGYIDTLYLNEKKEITEGSISNIFVKIGDSYFTPPISSGVL
HHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHCCCCCCCEEEEEECCCCCCCCCCCCCC
PGVFRNRLLKRNGFYEKTLCLDDLQRSNSIFLCNSLRGILRVKEVHKPKKE
CHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIIEELIFSGQPFMIFDEGFHPFGKIIFRNPIKTIEAYCFDTLSTSLNEINDCLKQGYYV
CCHHHHHHCCCCEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
AGFISYEVGYFFFNMNWKKTETGLPILYFAVFQKPEKLAEIQTELSQNYGFYISSMPNHE
EEEEEEEEEEEEEECCCEECCCCCCEEEHHHHCCHHHHHHHHHHHHCCCCEEEECCCCHH
NYIQSLDTIRTKLYQGEIYQINYTDKIFFDFEGDTLSFYKILSQRQPVAYGSWIRFRDID
HHHHHHHHHHHHHHCCCEEEEECCEEEEEEECCCCHHHHHHHHCCCCCCCCCEEEEEEEE
ILSFSPELFFEKKGTTLVTKPMKGTYQRGKSEKEDEKNIQILLNSEKEKAENLMITDLMR
EEEECCHHEEECCCCEEEECCCCCHHHCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHH
NDLGKISKKGSVQVPALFSIEKYKTILQMTSTIRSELSDWVEWKDIFRELFPGGSITGAP
HHHHHHCCCCCEECCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
KFRAMQLIQQLEKSRGIYTGAIGVIEPDQNAVFSIGIRTLELKKGKGNIGIGSGITWDSD
HHHHHHHHHHHHHHCCEEEEEEEEEECCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCC
PEKEWLEILEKAKFFTEAPQGFFLFETILYKNGIFYFLKEHLERIKKSAEIFQFPFSKKE
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHH
WDTSLKQIASISPGPSSYRIKISLNPLGKFHFESHKLSKFQKEGILQISEIEIDSSSEFR
HHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEEEECCCHHHH
KHKTNLREIYDREGKRSRDAGYIDTLYLNEKKEITEGSISNIFVKIGDSYFTPPISSGVL
HHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHCCCCCCCEEEEEECCCCCCCCCCCCCC
PGVFRNRLLKRNGFYEKTLCLDDLQRSNSIFLCNSLRGILRVKEVHKPKKE
CHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]