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The map label for this gene is aat

Identifier: 116326893

GI number: 116326893

Start: 57394

End: 58053

Strand: Direct

Name: aat

Synonym: LBL_0048

Alternate gene names: 116326893

Gene position: 57394-58053 (Clockwise)

Preceding gene: 116326892

Following gene: 116326894

Centisome position: 1.59

GC content: 39.39

Gene sequence:

>660_bases
TTGAAAGATTTTTCTGATTTTTTTCGAAACCCTCATATTTGGGATCGCGAGATTGTCGCAGTGGGTGGGGATCTTTCTCC
GGAACGACTTTTATACGCCTATAAAAATGGAATTTTTCCTTGGTCGGATCAGCCAATTCTTTGGTATTGTTTGGACCCGA
GAGGAATTTTCGATCTCAATAAACTTCATATTTCAAAACGGTTGAAAAGAAAAATCAATCAAAAGCGCTATACGATCACT
TTCAACCGAGCCTTTGAACAAGTTATGCGCTGTTGTGCATACCGTCCCGGTGAAGAAACCTGGATCACGGATCTTTTCAT
CAAAAGTTACACCGAATTTCACAAATTAGGTTATGCTCATTCCATAGAAGTTTGGGATGAAAACGGAAATTTGGGGGGTG
GGGTCTATGGAGTTGCAATTGGAAATTTTTTTGCAGGCGAGTCCATGTTTTCTTTCATTTCAGATTTCGGGAAAATCGGA
CTCTTTCATTTATTCGAAGCCCTAAAAAAAGATCAATTCACATTGTTCGATACCCAGCAACTAAACATTGTTACCCTATG
TTTGGGGGCTTACCAAATTCCAAAAAAAGAATATCTTAGACGTTTGGAATCTGCCGTTGCTTCCGGTAAAAAATGGAACC
CTCTACGTACGGTTTTCTAA

Upstream 100 bases:

>100_bases
TTTCATTGAAGAATCTTTTTCGCTTTTACCGTCTTACAAAAATAATAAGAGGCCCGAATCATAAAAGACGCGAAAAGTTG
TAAAATGATAGGGAATAAGC

Downstream 100 bases:

>100_bases
AAAACGTATTTACATTTTTGCTAAGGGTGTTGGACTTCTCCAATCATTCTATTCAATAGGAAATTTACCAATGACCCTTT
TTAAGAAAATTCTTGTACAA

Product: leucyl/phenylalanyl-tRNA--protein transferase

Products: NA

Alternate protein names: L/F-transferase; Leucyltransferase; Phenyalanyltransferase

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MKDFSDFFRNPHIWDREIVAVGGDLSPERLLYAYKNGIFPWSDQPILWYCLDPRGIFDLNKLHISKRLKRKINQKRYTIT
FNRAFEQVMRCCAYRPGEETWITDLFIKSYTEFHKLGYAHSIEVWDENGNLGGGVYGVAIGNFFAGESMFSFISDFGKIG
LFHLFEALKKDQFTLFDTQQLNIVTLCLGAYQIPKKEYLRRLESAVASGKKWNPLRTVF

Sequences:

>Translated_219_residues
MKDFSDFFRNPHIWDREIVAVGGDLSPERLLYAYKNGIFPWSDQPILWYCLDPRGIFDLNKLHISKRLKRKINQKRYTIT
FNRAFEQVMRCCAYRPGEETWITDLFIKSYTEFHKLGYAHSIEVWDENGNLGGGVYGVAIGNFFAGESMFSFISDFGKIG
LFHLFEALKKDQFTLFDTQQLNIVTLCLGAYQIPKKEYLRRLESAVASGKKWNPLRTVF
>Mature_219_residues
MKDFSDFFRNPHIWDREIVAVGGDLSPERLLYAYKNGIFPWSDQPILWYCLDPRGIFDLNKLHISKRLKRKINQKRYTIT
FNRAFEQVMRCCAYRPGEETWITDLFIKSYTEFHKLGYAHSIEVWDENGNLGGGVYGVAIGNFFAGESMFSFISDFGKIG
LFHLFEALKKDQFTLFDTQQLNIVTLCLGAYQIPKKEYLRRLESAVASGKKWNPLRTVF

Specific function: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine

COG id: COG2360

COG function: function code O; Leu/Phe-tRNA-protein transferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the L/F-transferase family

Homologues:

Organism=Escherichia coli, GI1787111, Length=187, Percent_Identity=47.0588235294118, Blast_Score=163, Evalue=9e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LFTR_LEPBJ (Q04W85)

Other databases:

- EMBL:   CP000350
- RefSeq:   YP_799593.1
- ProteinModelPortal:   Q04W85
- SMR:   Q04W85
- STRING:   Q04W85
- GeneID:   4411101
- GenomeReviews:   CP000350_GR
- KEGG:   lbj:LBJ_0088
- eggNOG:   COG2360
- HOGENOM:   HBG485363
- OMA:   IGESMFY
- PhylomeDB:   Q04W85
- ProtClustDB:   PRK00301
- BioCyc:   LBOR355277:LBJ_0088-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00688
- InterPro:   IPR016181
- InterPro:   IPR004616
- TIGRFAMs:   TIGR00667

Pfam domain/function: PF03588 Leu_Phe_trans; SSF55729 Acyl_CoA_acyltransferase

EC number: =2.3.2.6

Molecular weight: Translated: 25581; Mature: 25581

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDFSDFFRNPHIWDREIVAVGGDLSPERLLYAYKNGIFPWSDQPILWYCLDPRGIFDLN
CCCHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCHHH
KLHISKRLKRKINQKRYTITFNRAFEQVMRCCAYRPGEETWITDLFIKSYTEFHKLGYAH
HHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEE
SIEVWDENGNLGGGVYGVAIGNFFAGESMFSFISDFGKIGLFHLFEALKKDQFTLFDTQQ
EEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
LNIVTLCLGAYQIPKKEYLRRLESAVASGKKWNPLRTVF
CCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKDFSDFFRNPHIWDREIVAVGGDLSPERLLYAYKNGIFPWSDQPILWYCLDPRGIFDLN
CCCHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCHHH
KLHISKRLKRKINQKRYTITFNRAFEQVMRCCAYRPGEETWITDLFIKSYTEFHKLGYAH
HHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEE
SIEVWDENGNLGGGVYGVAIGNFFAGESMFSFISDFGKIGLFHLFEALKKDQFTLFDTQQ
EEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
LNIVTLCLGAYQIPKKEYLRRLESAVASGKKWNPLRTVF
CCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA