Click here to switch to the map view.

The map label for this gene is dnaX-1 [H]

Identifier: 116326855

GI number: 116326855

Start: 2979

End: 3917

Strand: Direct

Name: dnaX-1 [H]

Synonym: LBL_0003

Alternate gene names: 116326855

Gene position: 2979-3917 (Clockwise)

Preceding gene: 116326854

Following gene: 116326856

Centisome position: 0.08

GC content: 37.59

Gene sequence:

>939_bases
ATGTTTCGCTCTGCGTTTCAATTCGACGATATTTTAGGACAAGAGGTCGCTCTTACTTTTTTAAAAAGGTATACGTCAAA
ACCGGAGACAATTCCTCCTCTTCTTATCTTTCATGGCCCGGACGGAACCGGAAAAGAGTCTACTTCGGAGCGGTTTATTA
AAAATGTATTATGTTTTGAAGGAACTTCATGCGGGACTTGCGCTTCCTGTAAAGCTTTCATGCGAAATTCTCATCCGGAT
TACATATGTTTTCCGGAAGATCGCGGAAAAATTATAGCGATTGGAAGCGAGGATAATCCAGAAGAATTTACAATCCGTTG
GTTGATTCGTTCGCGATTGAATTATCGCCCTCATCTTTCGAAGTTTCGTTTTATCGTTTTCCCGGACGCGTCCCTCATCG
GAAACGAAGCAGAAACAGCCTTATTAAAATCCTTGGAAGAAGCTCCATCATTTTCAAAATTCATTTTTATCGTAAATAAC
ATAGACACACTTAAAGAGACAATCATAAGTCGGGCAATTTGTGTTCCATTCCAATATTTAAACCAAAATGACTTGAAAAA
AATCAATACGAACTTAGGACTTTCCACTCTTCCATTTCAAGGAGGAAGCCTCGCACCGTTCGAATGTCCGAAAGAAGTAA
TCGATCTGGTTCAGGAAAAAATTAAGGATAAATTAGAAACTAAACTCGATCTTCTAAAACTAGAGTCGTGGATTTCTTCT
TACAAAAACGAACATCCAGAGTGGAAAGAAAATTTCTCTTACAAGGAATTTTTAGAGTTGGTAAGTCTTACTTTAGTTTA
CGAGTATACGAGAACCGATTATGAAAATAATCTCTCAAAGATCGAGGCAATCTTTCAATTTAAGGCAGAACTTCATAAAA
GAATTGTCGGCATCGACACAATCGCACTTTCAAGACTATTTTTCCAACTTTCTCTTTAA

Upstream 100 bases:

>100_bases
GGGACCAATTACAAAAAAGATTCAAAGTTTATTCTTCAATCTTGTAATTAACAAAGAAGAAAAATACAGACATTGGTTGA
CTCCGGTTTATTGAAAAAGA

Downstream 100 bases:

>100_bases
CATATATTCTAAAAATTGAATATATATTCTCATAAAAATACATCGATACACGTTAACAGAAACACAAAATAAGCGGGTTT
CATATTTGAGACATAATTAA

Product: DNA polymerase III gamma and tau subunits

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MFRSAFQFDDILGQEVALTFLKRYTSKPETIPPLLIFHGPDGTGKESTSERFIKNVLCFEGTSCGTCASCKAFMRNSHPD
YICFPEDRGKIIAIGSEDNPEEFTIRWLIRSRLNYRPHLSKFRFIVFPDASLIGNEAETALLKSLEEAPSFSKFIFIVNN
IDTLKETIISRAICVPFQYLNQNDLKKINTNLGLSTLPFQGGSLAPFECPKEVIDLVQEKIKDKLETKLDLLKLESWISS
YKNEHPEWKENFSYKEFLELVSLTLVYEYTRTDYENNLSKIEAIFQFKAELHKRIVGIDTIALSRLFFQLSL

Sequences:

>Translated_312_residues
MFRSAFQFDDILGQEVALTFLKRYTSKPETIPPLLIFHGPDGTGKESTSERFIKNVLCFEGTSCGTCASCKAFMRNSHPD
YICFPEDRGKIIAIGSEDNPEEFTIRWLIRSRLNYRPHLSKFRFIVFPDASLIGNEAETALLKSLEEAPSFSKFIFIVNN
IDTLKETIISRAICVPFQYLNQNDLKKINTNLGLSTLPFQGGSLAPFECPKEVIDLVQEKIKDKLETKLDLLKLESWISS
YKNEHPEWKENFSYKEFLELVSLTLVYEYTRTDYENNLSKIEAIFQFKAELHKRIVGIDTIALSRLFFQLSL
>Mature_312_residues
MFRSAFQFDDILGQEVALTFLKRYTSKPETIPPLLIFHGPDGTGKESTSERFIKNVLCFEGTSCGTCASCKAFMRNSHPD
YICFPEDRGKIIAIGSEDNPEEFTIRWLIRSRLNYRPHLSKFRFIVFPDASLIGNEAETALLKSLEEAPSFSKFIFIVNN
IDTLKETIISRAICVPFQYLNQNDLKKINTNLGLSTLPFQGGSLAPFECPKEVIDLVQEKIKDKLETKLDLLKLESWISS
YKNEHPEWKENFSYKEFLELVSLTLVYEYTRTDYENNLSKIEAIFQFKAELHKRIVGIDTIALSRLFFQLSL

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG0470

COG function: function code L; ATPase involved in DNA replication

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786676, Length=189, Percent_Identity=28.5714285714286, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763
- InterPro:   IPR021029 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3; PF12170 DNA_pol3_tau_5 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 35932; Mature: 35932

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRSAFQFDDILGQEVALTFLKRYTSKPETIPPLLIFHGPDGTGKESTSERFIKNVLCFE
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHC
GTSCGTCASCKAFMRNSHPDYICFPEDRGKIIAIGSEDNPEEFTIRWLIRSRLNYRPHLS
CCCCCCHHHHHHHHHCCCCCEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCC
KFRFIVFPDASLIGNEAETALLKSLEEAPSFSKFIFIVNNIDTLKETIISRAICVPFQYL
CEEEEEECCHHHHCCHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHC
NQNDLKKINTNLGLSTLPFQGGSLAPFECPKEVIDLVQEKIKDKLETKLDLLKLESWISS
CCHHHHHHHCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YKNEHPEWKENFSYKEFLELVSLTLVYEYTRTDYENNLSKIEAIFQFKAELHKRIVGIDT
HCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IALSRLFFQLSL
HHHHHHHHHHCC
>Mature Secondary Structure
MFRSAFQFDDILGQEVALTFLKRYTSKPETIPPLLIFHGPDGTGKESTSERFIKNVLCFE
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHC
GTSCGTCASCKAFMRNSHPDYICFPEDRGKIIAIGSEDNPEEFTIRWLIRSRLNYRPHLS
CCCCCCHHHHHHHHHCCCCCEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCC
KFRFIVFPDASLIGNEAETALLKSLEEAPSFSKFIFIVNNIDTLKETIISRAICVPFQYL
CEEEEEECCHHHHCCHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHC
NQNDLKKINTNLGLSTLPFQGGSLAPFECPKEVIDLVQEKIKDKLETKLDLLKLESWISS
CCHHHHHHHCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YKNEHPEWKENFSYKEFLELVSLTLVYEYTRTDYENNLSKIEAIFQFKAELHKRIVGIDT
HCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IALSRLFFQLSL
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]