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The map label for this gene is argD

Identifier: 229221143

GI number: 229221143

Start: 2795449

End: 2796633

Strand: Direct

Name: argD

Synonym: Bamb_2538

Alternate gene names: 229221143

Gene position: 2795449-2796633 (Clockwise)

Preceding gene: 115352588

Following gene: 115352590

Centisome position: 78.6

GC content: 65.65

Gene sequence:

>1185_bases
ATGCCCCTGAACGATTACCCGATCGACTCGCTGATGTACATCACGAACCGCCCCGACATCGTGTTTACGCACGGCAAGGG
TTCGTGGCTCTACGATCACACGGGCAAGCGCTATCTGGACTTCATCCAGGGTTGGGCCGTCAACAGCCTCGGCCACTGCA
ACGACGGCGTCGTCGAAGCGCTGAAGACCCAGGCGGAAAAGCTGCTGAACCCGTCACCGGCGTTCTACAACGAGCCGATG
GCGAAGCTCGCGGGGCTGCTCACGCAGCACAGCGTATTCGACAAGGTGTTCTTCACGAACAGCGGCGCCGAGGCCAATGA
AGGCGCGATCAAGCTCGCGCGCAAGTGGGGCCGCAAGTTCCGCAACGGCGCGTACGAGATCATCACGTTCGACCACAGCT
TCCACGGCCGCACGCTCGCGACGATGTCGGCCAGCGGCAAGCCGGGCTGGGACACCATCTACGCGCCGCAGGTGCCGGGC
TTCCCGAAGGCCGAACTGAACAACATCAACTCGGTCGAGAAGCTGATCACCGACAAGACCGTCGCGGTGATGCTCGAGCC
GATCCAGGGCGAAGGCGGCGTGATTCCGGCGACGCCCGAGTTCATGCGCGAGCTGCGCGCGCTGACGAAGCAGCACAACC
TGCTGCTGATCGTCGACGAAGTGCAGAGCGGCTGCGGCCGCGCGGGCACGCTGTTCGCGTATGAGCTGTCCGACATCGAG
CCGGACATCATGACGCTCGGCAAGGGCATCGGCAGCGGCGTGCCGCTCGCGGCGCTGCTGTCGAAGGCCGACGTCGCGGT
ATTCGAGGCCGGCGATCAGGGCGGCACGTACAACGGCAACCCGCTGATGACGGCGGCCGGCTATTCGGTGATCTCGCAAC
TCGTCGCACCCGGCTTCCTCGAAGGCGTGCGGGCGCGCGGCGAATACCTGAAGCGCAAGCTGCTCGAACTGTCGGAGGAG
CGCGGCTTCGAGGGCGAGCGCGGCGAAGGGCTGCTGCGCGCGCTGCTGCTCGGCAAGGACATCGGCCCGCAGATCGTCGA
GAAGGCGCGCGACATGCAGCCCGACGGCCTGCTGCTGAACGCGGCGCGCCCGAACCTGCTGCGCTTCATGCCCGCGCTGA
CCGTGACGACCGAGGAAATCGACCAGATGATGGCGATGCTGCGGTCGATCCTCGACACGCTCTAA

Upstream 100 bases:

>100_bases
CTTCACCGGTTACGCACAAGCTGTTCGATCCACCAGCCACGGCCTTCCGTGGCTTTTTTATTGCCCGTTTCCCTTTCAAC
GCCCGCTGGAGTCTGCTGCC

Downstream 100 bases:

>100_bases
GGAGACTGCCGCGATGGATGCCGCCGCCGATACTGTCGCCGATGCTATTGCCATCCGCCCGTTCGAACGCGCCGACACCG
ATGCCGTGCTGGCCGTCTGG

Product: acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MPLNDYPIDSLMYITNRPDIVFTHGKGSWLYDHTGKRYLDFIQGWAVNSLGHCNDGVVEALKTQAEKLLNPSPAFYNEPM
AKLAGLLTQHSVFDKVFFTNSGAEANEGAIKLARKWGRKFRNGAYEIITFDHSFHGRTLATMSASGKPGWDTIYAPQVPG
FPKAELNNINSVEKLITDKTVAVMLEPIQGEGGVIPATPEFMRELRALTKQHNLLLIVDEVQSGCGRAGTLFAYELSDIE
PDIMTLGKGIGSGVPLAALLSKADVAVFEAGDQGGTYNGNPLMTAAGYSVISQLVAPGFLEGVRARGEYLKRKLLELSEE
RGFEGERGEGLLRALLLGKDIGPQIVEKARDMQPDGLLLNAARPNLLRFMPALTVTTEEIDQMMAMLRSILDTL

Sequences:

>Translated_394_residues
MPLNDYPIDSLMYITNRPDIVFTHGKGSWLYDHTGKRYLDFIQGWAVNSLGHCNDGVVEALKTQAEKLLNPSPAFYNEPM
AKLAGLLTQHSVFDKVFFTNSGAEANEGAIKLARKWGRKFRNGAYEIITFDHSFHGRTLATMSASGKPGWDTIYAPQVPG
FPKAELNNINSVEKLITDKTVAVMLEPIQGEGGVIPATPEFMRELRALTKQHNLLLIVDEVQSGCGRAGTLFAYELSDIE
PDIMTLGKGIGSGVPLAALLSKADVAVFEAGDQGGTYNGNPLMTAAGYSVISQLVAPGFLEGVRARGEYLKRKLLELSEE
RGFEGERGEGLLRALLLGKDIGPQIVEKARDMQPDGLLLNAARPNLLRFMPALTVTTEEIDQMMAMLRSILDTL
>Mature_393_residues
PLNDYPIDSLMYITNRPDIVFTHGKGSWLYDHTGKRYLDFIQGWAVNSLGHCNDGVVEALKTQAEKLLNPSPAFYNEPMA
KLAGLLTQHSVFDKVFFTNSGAEANEGAIKLARKWGRKFRNGAYEIITFDHSFHGRTLATMSASGKPGWDTIYAPQVPGF
PKAELNNINSVEKLITDKTVAVMLEPIQGEGGVIPATPEFMRELRALTKQHNLLLIVDEVQSGCGRAGTLFAYELSDIEP
DIMTLGKGIGSGVPLAALLSKADVAVFEAGDQGGTYNGNPLMTAAGYSVISQLVAPGFLEGVRARGEYLKRKLLELSEER
GFEGERGEGLLRALLLGKDIGPQIVEKARDMQPDGLLLNAARPNLLRFMPALTVTTEEIDQMMAMLRSILDTL

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=378, Percent_Identity=31.4814814814815, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI284507298, Length=298, Percent_Identity=30.8724832214765, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI13994255, Length=427, Percent_Identity=28.3372365339578, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI37574042, Length=416, Percent_Identity=29.3269230769231, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI24119277, Length=416, Percent_Identity=27.1634615384615, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI226442705, Length=416, Percent_Identity=28.6057692307692, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI226442709, Length=386, Percent_Identity=29.5336787564767, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI188536080, Length=427, Percent_Identity=23.1850117096019, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI38679950, Length=427, Percent_Identity=23.1850117096019, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI38679946, Length=427, Percent_Identity=23.1850117096019, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1788044, Length=360, Percent_Identity=43.0555555555556, Blast_Score=281, Evalue=4e-77,
Organism=Escherichia coli, GI1789759, Length=369, Percent_Identity=40.9214092140921, Blast_Score=271, Evalue=7e-74,
Organism=Escherichia coli, GI1789016, Length=398, Percent_Identity=33.4170854271357, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI145693181, Length=391, Percent_Identity=31.2020460358056, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1787560, Length=398, Percent_Identity=30.9045226130653, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1786349, Length=332, Percent_Identity=31.6265060240964, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1786991, Length=311, Percent_Identity=29.2604501607717, Blast_Score=100, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI25144271, Length=380, Percent_Identity=32.8947368421053, Blast_Score=221, Evalue=4e-58,
Organism=Caenorhabditis elegans, GI32564660, Length=417, Percent_Identity=28.0575539568345, Blast_Score=155, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI25144274, Length=270, Percent_Identity=33.7037037037037, Blast_Score=154, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI71992977, Length=416, Percent_Identity=28.6057692307692, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI71981843, Length=159, Percent_Identity=31.4465408805031, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17541228, Length=348, Percent_Identity=25.2873563218391, Blast_Score=89, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6324432, Length=401, Percent_Identity=33.9152119700748, Blast_Score=209, Evalue=4e-55,
Organism=Saccharomyces cerevisiae, GI6323470, Length=398, Percent_Identity=31.4070351758794, Blast_Score=187, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6321456, Length=427, Percent_Identity=25.5269320843091, Blast_Score=97, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6324386, Length=462, Percent_Identity=25.7575757575758, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21357415, Length=378, Percent_Identity=33.0687830687831, Blast_Score=215, Evalue=4e-56,
Organism=Drosophila melanogaster, GI161085790, Length=415, Percent_Identity=27.710843373494, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28574759, Length=410, Percent_Identity=28.0487804878049, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI21356575, Length=427, Percent_Identity=26.463700234192, Blast_Score=128, Evalue=5e-30,
Organism=Drosophila melanogaster, GI281366494, Length=423, Percent_Identity=24.5862884160757, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24667139, Length=423, Percent_Identity=24.5862884160757, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24667143, Length=423, Percent_Identity=24.5862884160757, Blast_Score=85, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43072; Mature: 42941

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLNDYPIDSLMYITNRPDIVFTHGKGSWLYDHTGKRYLDFIQGWAVNSLGHCNDGVVEA
CCCCCCCCCCEEEEECCCCEEEECCCCCEEECCCCHHHHHHHHHHHCCCCCCCCHHHHHH
LKTQAEKLLNPSPAFYNEPMAKLAGLLTQHSVFDKVFFTNSGAEANEGAIKLARKWGRKF
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHH
RNGAYEIITFDHSFHGRTLATMSASGKPGWDTIYAPQVPGFPKAELNNINSVEKLITDKT
CCCCEEEEEECCCCCCCEEEEEECCCCCCCCCEECCCCCCCCCHHHCCHHHHHHHHHCCE
VAVMLEPIQGEGGVIPATPEFMRELRALTKQHNLLLIVDEVQSGCGRAGTLFAYELSDIE
EEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEHHHCCCCCCCEEEEEECCCCC
PDIMTLGKGIGSGVPLAALLSKADVAVFEAGDQGGTYNGNPLMTAAGYSVISQLVAPGFL
HHHHHHHCCCCCCCCHHHHHHHCCEEEEECCCCCCCCCCCEEEEHHHHHHHHHHHCCHHH
EGVRARGEYLKRKLLELSEERGFEGERGEGLLRALLLGKDIGPQIVEKARDMQPDGLLLN
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEE
AARPNLLRFMPALTVTTEEIDQMMAMLRSILDTL
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
PLNDYPIDSLMYITNRPDIVFTHGKGSWLYDHTGKRYLDFIQGWAVNSLGHCNDGVVEA
CCCCCCCCCEEEEECCCCEEEECCCCCEEECCCCHHHHHHHHHHHCCCCCCCCHHHHHH
LKTQAEKLLNPSPAFYNEPMAKLAGLLTQHSVFDKVFFTNSGAEANEGAIKLARKWGRKF
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHH
RNGAYEIITFDHSFHGRTLATMSASGKPGWDTIYAPQVPGFPKAELNNINSVEKLITDKT
CCCCEEEEEECCCCCCCEEEEEECCCCCCCCCEECCCCCCCCCHHHCCHHHHHHHHHCCE
VAVMLEPIQGEGGVIPATPEFMRELRALTKQHNLLLIVDEVQSGCGRAGTLFAYELSDIE
EEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEHHHCCCCCCCEEEEEECCCCC
PDIMTLGKGIGSGVPLAALLSKADVAVFEAGDQGGTYNGNPLMTAAGYSVISQLVAPGFL
HHHHHHHCCCCCCCCHHHHHHHCCEEEEECCCCCCCCCCCEEEEHHHHHHHHHHHCCHHH
EGVRARGEYLKRKLLELSEERGFEGERGEGLLRALLLGKDIGPQIVEKARDMQPDGLLLN
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEE
AARPNLLRFMPALTVTTEEIDQMMAMLRSILDTL
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]