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The map label for this gene is yjcE [H]

Identifier: 115353037

GI number: 115353037

Start: 3295781

End: 3297448

Strand: Direct

Name: yjcE [H]

Synonym: Bamb_2986

Alternate gene names: 115353037

Gene position: 3295781-3297448 (Clockwise)

Preceding gene: 115353034

Following gene: 115353038

Centisome position: 92.67

GC content: 68.76

Gene sequence:

>1668_bases
ATGGAAATCGTCTTCACAGTCCTGATTCTGCTGCTCACCGTCGCGCTGTCCGGCGCGGCCACGCGCGTGCTGCCGTTGCG
GCTTCCGCTGCCGCTGATGCAGATCGCGTTCGGCGCGATGCTCGCGTGGCCGAAGCTCAACCTGCACGTCACGTTCGATC
CCGAAATCTTCATGCTGCTGTTCATTCCGCCGCTGCTGTTCGCGGACGGCTGGCGGATTCCGAAACGCGAGCTGTACCTG
CAGCGCCGCGCGATCCTGATGCTCGCGTTCGGGCTCGTGTTCATGACCGTACTCGCAGTCGGCTACTTCGCGCACTGGCT
GATACCCGAGTTGCCGCTGCCGATCGCGTTCGCGCTCGCGGCCGTGCTGTCGCCCACCGACGCGGTCGCGCTGTCGGGCA
TCGCCGGCCGTGGCCGGATTCCGCCGCAACTGATGCACATCCTCGAAGGCGAAGCGCTGATGAACGATGCGTCGGGCCTC
GTCGCGCTGAAGTTCGCAGTCGCGGCCGCGCTCACGGGCGTGTTCTCACTGCGCGACGCGTCGATCACGTTCGTGATCGT
CGCGGCCGGCGGCCTGGCGACGGGCGCGGTCGTCGCGTGGCTGTTCAGCGCGCTGTCGACGCGCTTCCTGAACGCCGAGC
AGGAAGGCGACCCGGCCCCCGGGATCGTGATGACGCTGCTCGTGCCGTTCGCCGCCTATCTGTTCGCCGAGCACCTCGAC
CTGTCGGGCGTGCTCGCGGCCGTGTCGGCCGGGATGATGATGAATTACACGAGCTTCTCCCGCAAAAGCACCGTCGCGTC
GCGCGTGCGTGCCGAAAGCACGTGGGCGATGATCGAGTTCGTGTTCAACGGCATGGTGTTCATCATGCTCGGGCTGCAGT
TGCCGCACATCATCGGCCGCGCGCTCGTCGACGCGCACCACACGAGCGACGCGCTCGTCGGCCGGATGATCTTCAACGTG
TGCGCGATGATGCTCGCGCTGTATGCGATCCGCTTCCTGTGGGTCTGGCTGCTGCGCTGGATCGCGAGCCGCCGCGCCGC
GCGCCACGGCCTCGCGGGCACGATGGCCGGCATCCGCACGATCGCGGTGATGACGGTCGGCGGCGTGCGCGGCGCGGTCA
CGCTCGCGGGCGTGCTGTCGATTCCCGTCGCGCTGTCCGACGGCTCACCGCTGCCGGGGCGGGACACCGCGATCTTCGTC
GCGTCGGCGGTGATACTCGGCTCGCTGATCGTCGCGGTGATCGGGCTGCCGCTGCTGCTGCGCGGCGTGCGCTCGACGCG
CAACCCGCTCGCCGACGAGGAACGCACCGCGCGCGCGGCCGCCGCGCAGGCCGCGATTCGCGCGATCGACTCGTCGCACG
ACGCGATCTCGGCCGATCTCGACGAATCGGGCGCCGCGCGCTGCGCGGACATTTCCGCGCGCGTGATGGATCAGTACCGC
CGCCGCCTGGCCGCACTCGCCGAGGACGGCCCGACGCCGCGCGCGGAAGCGAAGCAGACCGAGACGATGGAACTGCAGAT
GCGGATCGCGGCGGTGCGCGCGGAACGCTCGGTGCTGTACCGGCTGCGCGGCGAAAGCAAGATTTCCGACGAGACGCTGA
CGAAGCTGATCCGCGAGATCGACCTGTCGGAAACGGCGCTGTCGACGCGCAAGAAAGGGATCGTCTGA

Upstream 100 bases:

>100_bases
CACCGTTTGCGTGCACGCGCACCGGCGCACTCGAACGCGCCCGTCACGTCGTCACGCTAAACTCCGTCCGGTCGTTTCAT
TCTCCACAATTGCCGTATCG

Downstream 100 bases:

>100_bases
CGCTCGGGCCGCGCAGCGGCCTGCTGCGACGCCCGTCGCATGCAACGCGGGACTAGACGCTTCCCTCTAGAAGCCGGCAT
TCAATTGGCGGCATATTCAA

Product: Na+/H+ antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 555; Mature: 555

Protein sequence:

>555_residues
MEIVFTVLILLLTVALSGAATRVLPLRLPLPLMQIAFGAMLAWPKLNLHVTFDPEIFMLLFIPPLLFADGWRIPKRELYL
QRRAILMLAFGLVFMTVLAVGYFAHWLIPELPLPIAFALAAVLSPTDAVALSGIAGRGRIPPQLMHILEGEALMNDASGL
VALKFAVAAALTGVFSLRDASITFVIVAAGGLATGAVVAWLFSALSTRFLNAEQEGDPAPGIVMTLLVPFAAYLFAEHLD
LSGVLAAVSAGMMMNYTSFSRKSTVASRVRAESTWAMIEFVFNGMVFIMLGLQLPHIIGRALVDAHHTSDALVGRMIFNV
CAMMLALYAIRFLWVWLLRWIASRRAARHGLAGTMAGIRTIAVMTVGGVRGAVTLAGVLSIPVALSDGSPLPGRDTAIFV
ASAVILGSLIVAVIGLPLLLRGVRSTRNPLADEERTARAAAAQAAIRAIDSSHDAISADLDESGAARCADISARVMDQYR
RRLAALAEDGPTPRAEAKQTETMELQMRIAAVRAERSVLYRLRGESKISDETLTKLIREIDLSETALSTRKKGIV

Sequences:

>Translated_555_residues
MEIVFTVLILLLTVALSGAATRVLPLRLPLPLMQIAFGAMLAWPKLNLHVTFDPEIFMLLFIPPLLFADGWRIPKRELYL
QRRAILMLAFGLVFMTVLAVGYFAHWLIPELPLPIAFALAAVLSPTDAVALSGIAGRGRIPPQLMHILEGEALMNDASGL
VALKFAVAAALTGVFSLRDASITFVIVAAGGLATGAVVAWLFSALSTRFLNAEQEGDPAPGIVMTLLVPFAAYLFAEHLD
LSGVLAAVSAGMMMNYTSFSRKSTVASRVRAESTWAMIEFVFNGMVFIMLGLQLPHIIGRALVDAHHTSDALVGRMIFNV
CAMMLALYAIRFLWVWLLRWIASRRAARHGLAGTMAGIRTIAVMTVGGVRGAVTLAGVLSIPVALSDGSPLPGRDTAIFV
ASAVILGSLIVAVIGLPLLLRGVRSTRNPLADEERTARAAAAQAAIRAIDSSHDAISADLDESGAARCADISARVMDQYR
RRLAALAEDGPTPRAEAKQTETMELQMRIAAVRAERSVLYRLRGESKISDETLTKLIREIDLSETALSTRKKGIV
>Mature_555_residues
MEIVFTVLILLLTVALSGAATRVLPLRLPLPLMQIAFGAMLAWPKLNLHVTFDPEIFMLLFIPPLLFADGWRIPKRELYL
QRRAILMLAFGLVFMTVLAVGYFAHWLIPELPLPIAFALAAVLSPTDAVALSGIAGRGRIPPQLMHILEGEALMNDASGL
VALKFAVAAALTGVFSLRDASITFVIVAAGGLATGAVVAWLFSALSTRFLNAEQEGDPAPGIVMTLLVPFAAYLFAEHLD
LSGVLAAVSAGMMMNYTSFSRKSTVASRVRAESTWAMIEFVFNGMVFIMLGLQLPHIIGRALVDAHHTSDALVGRMIFNV
CAMMLALYAIRFLWVWLLRWIASRRAARHGLAGTMAGIRTIAVMTVGGVRGAVTLAGVLSIPVALSDGSPLPGRDTAIFV
ASAVILGSLIVAVIGLPLLLRGVRSTRNPLADEERTARAAAAQAAIRAIDSSHDAISADLDESGAARCADISARVMDQYR
RRLAALAEDGPTPRAEAKQTETMELQMRIAAVRAERSVLYRLRGESKISDETLTKLIREIDLSETALSTRKKGIV

Specific function: Unknown

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [H]

Homologues:

Organism=Homo sapiens, GI27734935, Length=268, Percent_Identity=23.8805970149254, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI5454070, Length=291, Percent_Identity=23.0240549828179, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI110227626, Length=267, Percent_Identity=24.3445692883895, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI294997330, Length=267, Percent_Identity=24.3445692883895, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI41872703, Length=276, Percent_Identity=24.6376811594203, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI14211919, Length=262, Percent_Identity=24.8091603053435, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI15529998, Length=466, Percent_Identity=21.6738197424893, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI148727259, Length=266, Percent_Identity=25.187969924812, Blast_Score=67, Evalue=6e-11,
Organism=Escherichia coli, GI1790501, Length=555, Percent_Identity=48.2882882882883, Blast_Score=483, Evalue=1e-137,
Organism=Caenorhabditis elegans, GI71980847, Length=395, Percent_Identity=25.0632911392405, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71999819, Length=396, Percent_Identity=24.2424242424242, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI71999817, Length=396, Percent_Identity=24.2424242424242, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71999821, Length=396, Percent_Identity=24.2424242424242, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI71990932, Length=393, Percent_Identity=24.4274809160305, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71990924, Length=393, Percent_Identity=24.1730279898219, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI25150332, Length=368, Percent_Identity=23.3695652173913, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71993590, Length=290, Percent_Identity=25.5172413793103, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71993582, Length=289, Percent_Identity=25.6055363321799, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71987537, Length=517, Percent_Identity=21.4700193423598, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71987535, Length=517, Percent_Identity=21.4700193423598, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320663, Length=261, Percent_Identity=24.5210727969349, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221473212, Length=446, Percent_Identity=22.6457399103139, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI281364513, Length=266, Percent_Identity=25.5639097744361, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI221473215, Length=266, Percent_Identity=25.5639097744361, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI221473222, Length=266, Percent_Identity=25.5639097744361, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI221510734, Length=452, Percent_Identity=24.3362831858407, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI221510738, Length=452, Percent_Identity=24.3362831858407, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281360447, Length=317, Percent_Identity=24.2902208201893, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI221510732, Length=342, Percent_Identity=25.7309941520468, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI221510736, Length=342, Percent_Identity=25.7309941520468, Blast_Score=66, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24585580, Length=342, Percent_Identity=25.7309941520468, Blast_Score=66, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24585578, Length=342, Percent_Identity=25.7309941520468, Blast_Score=66, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR018422
- InterPro:   IPR004705 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 59696; Mature: 59696

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIVFTVLILLLTVALSGAATRVLPLRLPLPLMQIAFGAMLAWPKLNLHVTFDPEIFMLL
CHHHHHHHHHHHHHHHCCCHHEEEEEECCHHHHHHHHHHHHCCCCEEEEEEECCHHHHHH
FIPPLLFADGWRIPKRELYLQRRAILMLAFGLVFMTVLAVGYFAHWLIPELPLPIAFALA
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
AVLSPTDAVALSGIAGRGRIPPQLMHILEGEALMNDASGLVALKFAVAAALTGVFSLRDA
HHHCCCHHHHHCCCCCCCCCCHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHCCCC
SITFVIVAAGGLATGAVVAWLFSALSTRFLNAEQEGDPAPGIVMTLLVPFAAYLFAEHLD
CEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
LSGVLAAVSAGMMMNYTSFSRKSTVASRVRAESTWAMIEFVFNGMVFIMLGLQLPHIIGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALVDAHHTSDALVGRMIFNVCAMMLALYAIRFLWVWLLRWIASRRAARHGLAGTMAGIRT
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
IAVMTVGGVRGAVTLAGVLSIPVALSDGSPLPGRDTAIFVASAVILGSLIVAVIGLPLLL
HHHHEECCCHHHHHHHHHHHCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RGVRSTRNPLADEERTARAAAAQAAIRAIDSSHDAISADLDESGAARCADISARVMDQYR
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
RRLAALAEDGPTPRAEAKQTETMELQMRIAAVRAERSVLYRLRGESKISDETLTKLIREI
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
DLSETALSTRKKGIV
CCHHHHHHHHHCCCC
>Mature Secondary Structure
MEIVFTVLILLLTVALSGAATRVLPLRLPLPLMQIAFGAMLAWPKLNLHVTFDPEIFMLL
CHHHHHHHHHHHHHHHCCCHHEEEEEECCHHHHHHHHHHHHCCCCEEEEEEECCHHHHHH
FIPPLLFADGWRIPKRELYLQRRAILMLAFGLVFMTVLAVGYFAHWLIPELPLPIAFALA
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
AVLSPTDAVALSGIAGRGRIPPQLMHILEGEALMNDASGLVALKFAVAAALTGVFSLRDA
HHHCCCHHHHHCCCCCCCCCCHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHCCCC
SITFVIVAAGGLATGAVVAWLFSALSTRFLNAEQEGDPAPGIVMTLLVPFAAYLFAEHLD
CEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
LSGVLAAVSAGMMMNYTSFSRKSTVASRVRAESTWAMIEFVFNGMVFIMLGLQLPHIIGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALVDAHHTSDALVGRMIFNVCAMMLALYAIRFLWVWLLRWIASRRAARHGLAGTMAGIRT
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
IAVMTVGGVRGAVTLAGVLSIPVALSDGSPLPGRDTAIFVASAVILGSLIVAVIGLPLLL
HHHHEECCCHHHHHHHHHHHCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RGVRSTRNPLADEERTARAAAAQAAIRAIDSSHDAISADLDESGAARCADISARVMDQYR
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
RRLAALAEDGPTPRAEAKQTETMELQMRIAAVRAERSVLYRLRGESKISDETLTKLIREI
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
DLSETALSTRKKGIV
CCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]