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The map label for this gene is bioA [H]

Identifier: 115353031

GI number: 115353031

Start: 3288695

End: 3290074

Strand: Direct

Name: bioA [H]

Synonym: Bamb_2980

Alternate gene names: 115353031

Gene position: 3288695-3290074 (Clockwise)

Preceding gene: 115353030

Following gene: 115353032

Centisome position: 92.47

GC content: 70.58

Gene sequence:

>1380_bases
ATGCCCGCCGCCGTTTTACCCCCCGGAGTCGCCTTGAGTACGCCAGCCACCGACGACTGGGTCGCGCGCAGCCTGCGCGC
GGTCTGGCATCCCTGCACCCAGATGAAGCACCACGAGCGCCTGCCGCTCATTCCCGTCGCGCGCGGCGCGGGCGTGTGGC
TGTACGACCGCGACGGCCGCCGCTACTTCGATGCGATCAGCTCATGGTGGGTGAACCTGTTCGGCCATGCGAACCCGGAC
ATCAACGCGGCACTGAAGGACCAGCTCGACACGCTCGAGCACGCGATGCTCGCCGGCTGCACGCACGAGCCGGCGATCGA
ACTCGCCGAGCGGCTGCACGCGCTCACCGCGCGCACGCTCGGCCATGCGTTCTTCGCGTCGGACGGCGCGTCGGCGGTCG
AGATCGCGCTGAAGATGAGCTTCCACGCGTGGCGCAACCGCGGCCGCGCGGACAAGCGCGAGTTCGTGTGCGTCGCGAAC
AGCTATCACGGCGAGACCATCGGCGCGCTCGGCGTGACCGACGTGGCGCTGTTCAAGGATGCGTACGATCCGCTGATCCG
CAACGCACACGTGGTCGCGTCGCCCGATGCGCGCGGCGCGCAGCCGGGCGAAACGGCCGCCGACGTCGCGGGCCGCGCGC
TCGACGACGTGCGGCGCCTGTTCGCCGAACGCGCGGACCGGATCGCCGCGCTGATCGTCGAGCCGCTCGTGCAATGCGCG
GCCGGCATGGCGATGCACGATCCGTCGTACGTGCGCGGGCTGCGCGCGCTGTGCGACGAATTCGGCGTGCATCTGATCGC
CGACGAGATCGCGGTCGGCTGCGGCCGCACCGGCACCTTCTTCGCGTGCGAACAGGCCGGCGTCTGGCCCGATTTCCTGT
GCCTGTCGAAGGGCATCAGCGGCGGCTACCTGCCGCTGTCGCTCGTGCTCACGCGCGACGACGTGTTCGCGGCCTTCTAC
GACGACGACACGACGCGCGGCTTCCTGCATTCGCATTCGTACACGGGCAACCCGCTCGCGTGCCGCGCGGCGGTCGCGAC
GCTCGACCTGTTCGCGCGCGACGACGTGCTCGCCGCCAACACGCGCAAGTCGGCCGCGATGCGCGCCGCGCTCGCGCCGC
TCGACGCGCACCCGCAGGTGCGTCACCTGCGCGAGCGCGGCACGCTGTTCGCATTCGACGTCGCGCTCGACGGCGACGCG
GCACGCGGCTTCTCGCGGCGCTTCTTCGAGCGCGCGCTCGAACGCGAACTGCTGCTGCGTCCGATCGGCACGACTGTGTA
CCTGATGCCGCCGTACGTGATGAGCGACGACGACATCGCGTGGCTTGCGCAGCGCACGCGCGACACGCTGGATGCGACGC
TCGCGGAGATCATGCAATGA

Upstream 100 bases:

>100_bases
CCGACAAGGCTTTGCGGCGTTTGTAACCGGTAGTGCAACGCGCGGCGGAACACGCTAATCTCAGCGCGTTTTCCGTCTGT
CGCCGCGCGGCATCCGTTCG

Downstream 100 bases:

>100_bases
CACAAACGGCCCCAAGTTCACTTCGTTCGCTGCCCCCCGAGGGGGCGGCAACGACGAACCTGCTCGATACGCTGCAACGC
GGCCTCGCCGAGCTCGACGC

Product: adenosylmethionine--8-amino-7-oxononanoate transaminase

Products: NA

Alternate protein names: 7,8-diamino-pelargonic acid aminotransferase; DAPA AT; DAPA aminotransferase; Diaminopelargonic acid synthase [H]

Number of amino acids: Translated: 459; Mature: 458

Protein sequence:

>459_residues
MPAAVLPPGVALSTPATDDWVARSLRAVWHPCTQMKHHERLPLIPVARGAGVWLYDRDGRRYFDAISSWWVNLFGHANPD
INAALKDQLDTLEHAMLAGCTHEPAIELAERLHALTARTLGHAFFASDGASAVEIALKMSFHAWRNRGRADKREFVCVAN
SYHGETIGALGVTDVALFKDAYDPLIRNAHVVASPDARGAQPGETAADVAGRALDDVRRLFAERADRIAALIVEPLVQCA
AGMAMHDPSYVRGLRALCDEFGVHLIADEIAVGCGRTGTFFACEQAGVWPDFLCLSKGISGGYLPLSLVLTRDDVFAAFY
DDDTTRGFLHSHSYTGNPLACRAAVATLDLFARDDVLAANTRKSAAMRAALAPLDAHPQVRHLRERGTLFAFDVALDGDA
ARGFSRRFFERALERELLLRPIGTTVYLMPPYVMSDDDIAWLAQRTRDTLDATLAEIMQ

Sequences:

>Translated_459_residues
MPAAVLPPGVALSTPATDDWVARSLRAVWHPCTQMKHHERLPLIPVARGAGVWLYDRDGRRYFDAISSWWVNLFGHANPD
INAALKDQLDTLEHAMLAGCTHEPAIELAERLHALTARTLGHAFFASDGASAVEIALKMSFHAWRNRGRADKREFVCVAN
SYHGETIGALGVTDVALFKDAYDPLIRNAHVVASPDARGAQPGETAADVAGRALDDVRRLFAERADRIAALIVEPLVQCA
AGMAMHDPSYVRGLRALCDEFGVHLIADEIAVGCGRTGTFFACEQAGVWPDFLCLSKGISGGYLPLSLVLTRDDVFAAFY
DDDTTRGFLHSHSYTGNPLACRAAVATLDLFARDDVLAANTRKSAAMRAALAPLDAHPQVRHLRERGTLFAFDVALDGDA
ARGFSRRFFERALERELLLRPIGTTVYLMPPYVMSDDDIAWLAQRTRDTLDATLAEIMQ
>Mature_458_residues
PAAVLPPGVALSTPATDDWVARSLRAVWHPCTQMKHHERLPLIPVARGAGVWLYDRDGRRYFDAISSWWVNLFGHANPDI
NAALKDQLDTLEHAMLAGCTHEPAIELAERLHALTARTLGHAFFASDGASAVEIALKMSFHAWRNRGRADKREFVCVANS
YHGETIGALGVTDVALFKDAYDPLIRNAHVVASPDARGAQPGETAADVAGRALDDVRRLFAERADRIAALIVEPLVQCAA
GMAMHDPSYVRGLRALCDEFGVHLIADEIAVGCGRTGTFFACEQAGVWPDFLCLSKGISGGYLPLSLVLTRDDVFAAFYD
DDTTRGFLHSHSYTGNPLACRAAVATLDLFARDDVLAANTRKSAAMRAALAPLDAHPQVRHLRERGTLFAFDVALDGDAA
RGFSRRFFERALERELLLRPIGTTVYLMPPYVMSDDDIAWLAQRTRDTLDATLAEIMQ

Specific function: Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor [H]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=429, Percent_Identity=28.6713286713287, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI37574042, Length=425, Percent_Identity=24.4705882352941, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI13994255, Length=387, Percent_Identity=25.8397932816537, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI226442705, Length=425, Percent_Identity=24.4705882352941, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI284507298, Length=316, Percent_Identity=28.1645569620253, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI226442709, Length=395, Percent_Identity=24.3037974683544, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI24119277, Length=431, Percent_Identity=24.1299303944316, Blast_Score=88, Evalue=2e-17,
Organism=Escherichia coli, GI1786991, Length=424, Percent_Identity=38.6792452830189, Blast_Score=257, Evalue=1e-69,
Organism=Escherichia coli, GI145693181, Length=404, Percent_Identity=29.9504950495049, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI1789016, Length=402, Percent_Identity=30.0995024875622, Blast_Score=158, Evalue=9e-40,
Organism=Escherichia coli, GI1789759, Length=405, Percent_Identity=28.8888888888889, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1788044, Length=398, Percent_Identity=28.391959798995, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1787560, Length=413, Percent_Identity=29.7820823244552, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1786349, Length=317, Percent_Identity=28.7066246056782, Blast_Score=101, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI25144271, Length=377, Percent_Identity=27.8514588859416, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI32564660, Length=421, Percent_Identity=23.9904988123515, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI25144274, Length=221, Percent_Identity=30.316742081448, Blast_Score=99, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6324386, Length=481, Percent_Identity=28.2744282744283, Blast_Score=201, Evalue=3e-52,
Organism=Saccharomyces cerevisiae, GI6323470, Length=459, Percent_Identity=28.322440087146, Blast_Score=130, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6324432, Length=420, Percent_Identity=25.952380952381, Blast_Score=118, Evalue=2e-27,
Organism=Drosophila melanogaster, GI21357415, Length=421, Percent_Identity=27.5534441805226, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI161085790, Length=380, Percent_Identity=26.0526315789474, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28574759, Length=380, Percent_Identity=26.0526315789474, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI21356575, Length=318, Percent_Identity=23.8993710691824, Blast_Score=103, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR005815
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.62 [H]

Molecular weight: Translated: 50244; Mature: 50112

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00436 PEROXIDASE_2 ; PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAAVLPPGVALSTPATDDWVARSLRAVWHPCTQMKHHERLPLIPVARGAGVWLYDRDGR
CCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEEEECCCH
RYFDAISSWWVNLFGHANPDINAALKDQLDTLEHAMLAGCTHEPAIELAERLHALTARTL
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
GHAFFASDGASAVEIALKMSFHAWRNRGRADKREFVCVANSYHGETIGALGVTDVALFKD
HHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEECCCCHHHHHHHHH
AYDPLIRNAHVVASPDARGAQPGETAADVAGRALDDVRRLFAERADRIAALIVEPLVQCA
HHHHHHHCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGMAMHDPSYVRGLRALCDEFGVHLIADEIAVGCGRTGTFFACEQAGVWPDFLCLSKGIS
CCCCCCCHHHHHHHHHHHHHHCCEEEHHHHHHCCCCCCCEEEECCCCCCHHHHHHHCCCC
GGYLPLSLVLTRDDVFAAFYDDDTTRGFLHSHSYTGNPLACRAAVATLDLFARDDVLAAN
CCCEEEEEEEECCCEEEEEECCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEECC
TRKSAAMRAALAPLDAHPQVRHLRERGTLFAFDVALDGDAARGFSRRFFERALERELLLR
CHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
PIGTTVYLMPPYVMSDDDIAWLAQRTRDTLDATLAEIMQ
CCCCEEEEECCEEECCCCHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
PAAVLPPGVALSTPATDDWVARSLRAVWHPCTQMKHHERLPLIPVARGAGVWLYDRDGR
CCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEEEECCCH
RYFDAISSWWVNLFGHANPDINAALKDQLDTLEHAMLAGCTHEPAIELAERLHALTARTL
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
GHAFFASDGASAVEIALKMSFHAWRNRGRADKREFVCVANSYHGETIGALGVTDVALFKD
HHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEECCCCHHHHHHHHH
AYDPLIRNAHVVASPDARGAQPGETAADVAGRALDDVRRLFAERADRIAALIVEPLVQCA
HHHHHHHCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGMAMHDPSYVRGLRALCDEFGVHLIADEIAVGCGRTGTFFACEQAGVWPDFLCLSKGIS
CCCCCCCHHHHHHHHHHHHHHCCEEEHHHHHHCCCCCCCEEEECCCCCCHHHHHHHCCCC
GGYLPLSLVLTRDDVFAAFYDDDTTRGFLHSHSYTGNPLACRAAVATLDLFARDDVLAAN
CCCEEEEEEEECCCEEEEEECCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEECC
TRKSAAMRAALAPLDAHPQVRHLRERGTLFAFDVALDGDAARGFSRRFFERALERELLLR
CHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
PIGTTVYLMPPYVMSDDDIAWLAQRTRDTLDATLAEIMQ
CCCCEEEEECCEEECCCCHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2110099 [H]