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The map label for this gene is csgA [H]

Identifier: 115353028

GI number: 115353028

Start: 3285391

End: 3286068

Strand: Direct

Name: csgA [H]

Synonym: Bamb_2977

Alternate gene names: 115353028

Gene position: 3285391-3286068 (Clockwise)

Preceding gene: 115353027

Following gene: 115353029

Centisome position: 92.38

GC content: 70.35

Gene sequence:

>678_bases
ATGAAAACCGTACTGATCGTCGGCGCATCGCGCGGCTTGGGGCGCGAATTCGTCCGGCAATACCGCCGCGACGGCTGGAA
CGTGATCGCGACCGCCCGCGACGACGCATCGCTCGCCGCGCTGCGCGAACTCGGCGCGCAAGCGTATGCGCTCGACATCG
CGCAACCCGAACAGATCGCGGCGCTCGGCTGGAAGCTCGACGGCGAACGGCTCGACGCGGCCGTGCTCGTGTCGGGCGTG
TACGGGCCGCGCACCGAAGGCGTCGAGACGATCGGCGCCGAGGATTTCGACGCGGTGATGCATACGAACGTGCGCGGGCC
GATGCAGCTGCTGCCGATCCTGCTGCCGCTCGTCGAGGACGCGCGCGGCGTGCTGGCCGTCGTCTCGAGCCGGATGGGCA
GCATCGCGGAAGCGACCGGCACGACCGGCTGGCTGTACCGTGCGAGCAAGGCCGCGCTGAACGACGTGCTGCGCATCGCG
TCGCTGCAGACGCGCCACGCCGCGTGCATCTCGCTCCATCCCGGCTGGGTGCGCACCGACATGGGCGGCGCGCAGGCCGC
GATCGATCCGGAAACCAGCGTGACCGGCATGCGCCGCGTGATCGCCGAAGCCGGCGCGGACGTGTCCCGCGCCAACGGCC
GTTTCTTCCAGTACGACGGCGTCGAGCTCAGTTGGTGA

Upstream 100 bases:

>100_bases
CTCCGGCTGAAGATGCACGCGAGCCTGGCCGCGACGGGTAGCGAACTGATCTGACACCGACACTGCCGCCACGGCGGTGC
AACGCAAAGGAGCGGCGAAC

Downstream 100 bases:

>100_bases
GCCGGCATGACAACCCGGCGTCGTTAATTCACGATTCGCATGAATTTGAACCGACCTGACGCGTGCCCGTGCGGCGGCGC
GTCCCCCACTCCCGCCGGCA

Product: short chain dehydrogenase

Products: NA

Alternate protein names: C signal [H]

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MKTVLIVGASRGLGREFVRQYRRDGWNVIATARDDASLAALRELGAQAYALDIAQPEQIAALGWKLDGERLDAAVLVSGV
YGPRTEGVETIGAEDFDAVMHTNVRGPMQLLPILLPLVEDARGVLAVVSSRMGSIAEATGTTGWLYRASKAALNDVLRIA
SLQTRHAACISLHPGWVRTDMGGAQAAIDPETSVTGMRRVIAEAGADVSRANGRFFQYDGVELSW

Sequences:

>Translated_225_residues
MKTVLIVGASRGLGREFVRQYRRDGWNVIATARDDASLAALRELGAQAYALDIAQPEQIAALGWKLDGERLDAAVLVSGV
YGPRTEGVETIGAEDFDAVMHTNVRGPMQLLPILLPLVEDARGVLAVVSSRMGSIAEATGTTGWLYRASKAALNDVLRIA
SLQTRHAACISLHPGWVRTDMGGAQAAIDPETSVTGMRRVIAEAGADVSRANGRFFQYDGVELSW
>Mature_225_residues
MKTVLIVGASRGLGREFVRQYRRDGWNVIATARDDASLAALRELGAQAYALDIAQPEQIAALGWKLDGERLDAAVLVSGV
YGPRTEGVETIGAEDFDAVMHTNVRGPMQLLPILLPLVEDARGVLAVVSSRMGSIAEATGTTGWLYRASKAALNDVLRIA
SLQTRHAACISLHPGWVRTDMGGAQAAIDPETSVTGMRRVIAEAGADVSRANGRFFQYDGVELSW

Specific function: Cell-cell signaling protein required for fruiting body morphogenesis. Necessary for cellular aggregation, for spore differentiation, and for gene expression that is initiated after 6 hour of starvation [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To yeast YKL071W [H]

Homologues:

Organism=Caenorhabditis elegans, GI17558994, Length=242, Percent_Identity=28.5123966942149, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI193207563, Length=246, Percent_Identity=26.8292682926829, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17558992, Length=246, Percent_Identity=29.2682926829268, Blast_Score=63, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24640547, Length=251, Percent_Identity=28.2868525896414, Blast_Score=95, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 24119; Mature: 24119

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTVLIVGASRGLGREFVRQYRRDGWNVIATARDDASLAALRELGAQAYALDIAQPEQIA
CCEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCEEEEECCCCHHHH
ALGWKLDGERLDAAVLVSGVYGPRTEGVETIGAEDFDAVMHTNVRGPMQLLPILLPLVED
HHCEEECCHHHCHHHEEECCCCCCCCCCHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHHH
ARGVLAVVSSRMGSIAEATGTTGWLYRASKAALNDVLRIASLQTRHAACISLHPGWVRTD
HHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEC
MGGAQAAIDPETSVTGMRRVIAEAGADVSRANGRFFQYDGVELSW
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCEEECC
>Mature Secondary Structure
MKTVLIVGASRGLGREFVRQYRRDGWNVIATARDDASLAALRELGAQAYALDIAQPEQIA
CCEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCEEEEECCCCHHHH
ALGWKLDGERLDAAVLVSGVYGPRTEGVETIGAEDFDAVMHTNVRGPMQLLPILLPLVED
HHCEEECCHHHCHHHEEECCCCCCCCCCHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHHH
ARGVLAVVSSRMGSIAEATGTTGWLYRASKAALNDVLRIASLQTRHAACISLHPGWVRTD
HHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEC
MGGAQAAIDPETSVTGMRRVIAEAGADVSRANGRFFQYDGVELSW
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2152896; 2107980; 2118510; 1372277 [H]