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The map label for this gene is dppA [H]

Identifier: 115353023

GI number: 115353023

Start: 3277381

End: 3278976

Strand: Direct

Name: dppA [H]

Synonym: Bamb_2972

Alternate gene names: 115353023

Gene position: 3277381-3278976 (Clockwise)

Preceding gene: 115353022

Following gene: 115353024

Centisome position: 92.15

GC content: 65.85

Gene sequence:

>1596_bases
ATGCACGCCAAGCTGTTCACCGCGGCCGCGCTCGCCGCCGCCCTCGCCGCTCCCGGCCTCGCCGTCGCCAAGCCGCTCAC
CGTCTGCACGGAATCGAGCCCGGACGGCTTCGACGTCGTGCAGTACAACTCACTCGTCACCACCAATGCGTCGGCCGACG
TGATCTTCAACACGCTCGTGTCGTACGACGAAGCCGCGAAGAAGGTCGTGCCGGCGCTCGCCGACAAATGGGAAGCCAGC
GCCGACGGTCTCACGTACACGTTCCACCTGCGGCCGAACGTCGCGTTCCAGACGACCGACTACTTCAAGCCGGGCCGCCC
GCTGAACGCGGACGACGTCGTGTTCACGTTCTCGCGGATGCTCGACGACGCGAACCCGTGGCACAAGGTGGCCGGCGCGA
GCGGCTTTCCGCACGCGCAGTCGATGGGCCTCGTGAAGCTCGTGAAGTCGGTCACGAAGGTCGACGACAGCACGGTGAAG
TTCGTGCTGAACGAGCCGAACGCGACGTTCGTGTCGATCCTGACGATGGGCTTCGCGTCGATCTACTCGGCCGAATACGC
GGACCAGCTGCTGAAGGCCGGCAAGCAGGCCGATCTAAACGCGAAGCCGGTCGGCACCGGCCCGTTCGTGCTGAAGAGCT
ACACGAAGGACGCGCTGATCCGCTACGACGTGAACCCGACCTACTGGGGCACGAAGCCGAAGGTCGACCGGCTGATCTAC
GCGATCACGCCGGACGCGTCCGTGCGCATGCAGAAGGTGAAGGCCGGCGAATGCCAGATCGCGCTGTCGCCGAAGCCGCA
GGACGTGCTCGCCGCGAAGGGCGAAAGCGCGCTGAAGGTCGTGCAGACGCCCGCGTTCATGACCGCGTTCGTCGCGCTGA
ACACGCAGAAGAAGCCGCTCGACAACGAGAAGGTGCGCGAGGCGCTGAACCTCGCGTTCGACCGCACGACCTACCTGAAG
GTCGTGTTCGACAACACGGCGACCGCCGCGAACAACCCGTATCCGCCGAACACGTGGAGCTACGCGAAGGACATCGCGCC
GTATGCGTACGATCCCGCGAAGGCGAAGCAGCTGCTCGCGTCGGCCGGGTTCCCGAACGGCTTCTCGACGACGATCTGGA
CGCGCCCGACGGGCAGCGTGCTGAACCCGAACCCGAAGGCCGGCGCGGAGCTGCTGCAGGCCGACCTCGCGAAGATCGGC
GTGAAGGCCGAGGTGAAGGTGATCGAATGGGGCGAGCTGATCAAGCAGGCGAAGCTCGGCCAGCATGACATGCTGTTCAT
GGGCTGGGCCGGCGACAACGGCGATCCGGACAATTACCTGTCGCCGCTGTTCAGCTGCAACGCGGTGAAGTCGGGCATCA
ACTTCGCGCGCTTCTGCGACGCGCAGCTCGACAAGCTGATCGCCGACGGCAAGGCGACCGCCGATCAGGCCAAGCGCGCG
AAGCTGTACGAATCGGCGCAGAAGGTGATCCACGACCAGGCGCTGTGGATTCCGCTCGGCTACCCGACCGCCGCCGCGCT
CACGCGCCCGAACGTGAGCGGCTATCACGTCAGTCCGTTCGGCCGCCAGAACTTCACGACCGTCTCCGTGCAGTAA

Upstream 100 bases:

>100_bases
CTATTCGCCAGCCGCGCCGCCCCGTCCACCACCGGGCCGCGCCTGCATTCCGCATGCATTCCGACATCCGGCAAAAATCA
CAAGTCACGTGGGAGAACCT

Downstream 100 bases:

>100_bases
CCGCGCGTGGCGCGCAAGCGACGGCATCCCGGCCCGTCGCTTGCGGCCCGCGCGGCGTGCTTGCTACACTGCGCGCTCAT
TCCTCATACCGGACGCCAGC

Product: extracellular solute-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 531; Mature: 531

Protein sequence:

>531_residues
MHAKLFTAAALAAALAAPGLAVAKPLTVCTESSPDGFDVVQYNSLVTTNASADVIFNTLVSYDEAAKKVVPALADKWEAS
ADGLTYTFHLRPNVAFQTTDYFKPGRPLNADDVVFTFSRMLDDANPWHKVAGASGFPHAQSMGLVKLVKSVTKVDDSTVK
FVLNEPNATFVSILTMGFASIYSAEYADQLLKAGKQADLNAKPVGTGPFVLKSYTKDALIRYDVNPTYWGTKPKVDRLIY
AITPDASVRMQKVKAGECQIALSPKPQDVLAAKGESALKVVQTPAFMTAFVALNTQKKPLDNEKVREALNLAFDRTTYLK
VVFDNTATAANNPYPPNTWSYAKDIAPYAYDPAKAKQLLASAGFPNGFSTTIWTRPTGSVLNPNPKAGAELLQADLAKIG
VKAEVKVIEWGELIKQAKLGQHDMLFMGWAGDNGDPDNYLSPLFSCNAVKSGINFARFCDAQLDKLIADGKATADQAKRA
KLYESAQKVIHDQALWIPLGYPTAAALTRPNVSGYHVSPFGRQNFTTVSVQ

Sequences:

>Translated_531_residues
MHAKLFTAAALAAALAAPGLAVAKPLTVCTESSPDGFDVVQYNSLVTTNASADVIFNTLVSYDEAAKKVVPALADKWEAS
ADGLTYTFHLRPNVAFQTTDYFKPGRPLNADDVVFTFSRMLDDANPWHKVAGASGFPHAQSMGLVKLVKSVTKVDDSTVK
FVLNEPNATFVSILTMGFASIYSAEYADQLLKAGKQADLNAKPVGTGPFVLKSYTKDALIRYDVNPTYWGTKPKVDRLIY
AITPDASVRMQKVKAGECQIALSPKPQDVLAAKGESALKVVQTPAFMTAFVALNTQKKPLDNEKVREALNLAFDRTTYLK
VVFDNTATAANNPYPPNTWSYAKDIAPYAYDPAKAKQLLASAGFPNGFSTTIWTRPTGSVLNPNPKAGAELLQADLAKIG
VKAEVKVIEWGELIKQAKLGQHDMLFMGWAGDNGDPDNYLSPLFSCNAVKSGINFARFCDAQLDKLIADGKATADQAKRA
KLYESAQKVIHDQALWIPLGYPTAAALTRPNVSGYHVSPFGRQNFTTVSVQ
>Mature_531_residues
MHAKLFTAAALAAALAAPGLAVAKPLTVCTESSPDGFDVVQYNSLVTTNASADVIFNTLVSYDEAAKKVVPALADKWEAS
ADGLTYTFHLRPNVAFQTTDYFKPGRPLNADDVVFTFSRMLDDANPWHKVAGASGFPHAQSMGLVKLVKSVTKVDDSTVK
FVLNEPNATFVSILTMGFASIYSAEYADQLLKAGKQADLNAKPVGTGPFVLKSYTKDALIRYDVNPTYWGTKPKVDRLIY
AITPDASVRMQKVKAGECQIALSPKPQDVLAAKGESALKVVQTPAFMTAFVALNTQKKPLDNEKVREALNLAFDRTTYLK
VVFDNTATAANNPYPPNTWSYAKDIAPYAYDPAKAKQLLASAGFPNGFSTTIWTRPTGSVLNPNPKAGAELLQADLAKIG
VKAEVKVIEWGELIKQAKLGQHDMLFMGWAGDNGDPDNYLSPLFSCNAVKSGINFARFCDAQLDKLIADGKATADQAKRA
KLYESAQKVIHDQALWIPLGYPTAAALTRPNVSGYHVSPFGRQNFTTVSVQ

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=536, Percent_Identity=44.0298507462687, Blast_Score=487, Evalue=1e-139,
Organism=Escherichia coli, GI1787551, Length=529, Percent_Identity=34.0264650283554, Blast_Score=317, Evalue=9e-88,
Organism=Escherichia coli, GI1787052, Length=527, Percent_Identity=30.9297912713473, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI1789887, Length=509, Percent_Identity=26.5225933202358, Blast_Score=145, Evalue=7e-36,
Organism=Escherichia coli, GI1787762, Length=482, Percent_Identity=25.5186721991701, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1787495, Length=529, Percent_Identity=24.7637051039698, Blast_Score=123, Evalue=4e-29,
Organism=Escherichia coli, GI87081878, Length=536, Percent_Identity=25.5597014925373, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1789397, Length=496, Percent_Identity=25.8064516129032, Blast_Score=106, Evalue=4e-24,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 57434; Mature: 57434

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHAKLFTAAALAAALAAPGLAVAKPLTVCTESSPDGFDVVQYNSLVTTNASADVIFNTLV
CCCHHHHHHHHHHHHHCCCHHHHCCEEEEECCCCCCCEEEEECCEEECCCCHHHHHHHHH
SYDEAAKKVVPALADKWEASADGLTYTFHLRPNVAFQTTDYFKPGRPLNADDVVFTFSRM
HHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCCHHHHHHHHH
LDDANPWHKVAGASGFPHAQSMGLVKLVKSVTKVDDSTVKFVLNEPNATFVSILTMGFAS
HCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHH
IYSAEYADQLLKAGKQADLNAKPVGTGPFVLKSYTKDALIRYDVNPTYWGTKPKVDRLIY
HHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEE
AITPDASVRMQKVKAGECQIALSPKPQDVLAAKGESALKVVQTPAFMTAFVALNTQKKPL
EECCCCCCEEEEECCCCEEEEECCCCHHHHHCCCCCHHHHHCCCHHHHHHHEECCCCCCC
DNEKVREALNLAFDRTTYLKVVFDNTATAANNPYPPNTWSYAKDIAPYAYDPAKAKQLLA
CHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHH
SAGFPNGFSTTIWTRPTGSVLNPNPKAGAELLQADLAKIGVKAEVKVIEWGELIKQAKLG
HCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHCC
QHDMLFMGWAGDNGDPDNYLSPLFSCNAVKSGINFARFCDAQLDKLIADGKATADQAKRA
CCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHH
KLYESAQKVIHDQALWIPLGYPTAAALTRPNVSGYHVSPFGRQNFTTVSVQ
HHHHHHHHHHHCCEEEEEECCCCHHHEECCCCCCEEECCCCCCCCEEEEEC
>Mature Secondary Structure
MHAKLFTAAALAAALAAPGLAVAKPLTVCTESSPDGFDVVQYNSLVTTNASADVIFNTLV
CCCHHHHHHHHHHHHHCCCHHHHCCEEEEECCCCCCCEEEEECCEEECCCCHHHHHHHHH
SYDEAAKKVVPALADKWEASADGLTYTFHLRPNVAFQTTDYFKPGRPLNADDVVFTFSRM
HHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCCHHHHHHHHH
LDDANPWHKVAGASGFPHAQSMGLVKLVKSVTKVDDSTVKFVLNEPNATFVSILTMGFAS
HCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHH
IYSAEYADQLLKAGKQADLNAKPVGTGPFVLKSYTKDALIRYDVNPTYWGTKPKVDRLIY
HHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEE
AITPDASVRMQKVKAGECQIALSPKPQDVLAAKGESALKVVQTPAFMTAFVALNTQKKPL
EECCCCCCEEEEECCCCEEEEECCCCHHHHHCCCCCHHHHHCCCHHHHHHHEECCCCCCC
DNEKVREALNLAFDRTTYLKVVFDNTATAANNPYPPNTWSYAKDIAPYAYDPAKAKQLLA
CHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHH
SAGFPNGFSTTIWTRPTGSVLNPNPKAGAELLQADLAKIGVKAEVKVIEWGELIKQAKLG
HCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHCC
QHDMLFMGWAGDNGDPDNYLSPLFSCNAVKSGINFARFCDAQLDKLIADGKATADQAKRA
CCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHH
KLYESAQKVIHDQALWIPLGYPTAAALTRPNVSGYHVSPFGRQNFTTVSVQ
HHHHHHHHHHHCCEEEEEECCCCHHHEECCCCCCEEECCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]