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The map label for this gene is hisC2 [H]

Identifier: 115352916

GI number: 115352916

Start: 3159078

End: 3160145

Strand: Direct

Name: hisC2 [H]

Synonym: Bamb_2865

Alternate gene names: 115352916

Gene position: 3159078-3160145 (Clockwise)

Preceding gene: 115352915

Following gene: 115352920

Centisome position: 88.82

GC content: 66.85

Gene sequence:

>1068_bases
GTGAGCCGTTACTGGAGCGACCTCGTTCAGCAACTCGTGCCTTACGTGCCGGGCGAACAGCCCGCACTCGCACACCCCGT
CAAGCTGAACACCAACGAGAATCCCTATCCGCCTTCGCCGCGCGTCGTCGCGGCGATCGCACGCGAACTCGGCGACACCG
GCGACACGCTGCGCCGCTATCCCGATCCGCTCGCGCGCGCACTGCGCGAGACGGTCGCGGCCCATCACCGCATCAAGCCC
GAACAGGTCTTCGTCGGCAACGGCTCCGATGAAGTGCTCGCGCATGCATTCCAGGCACTGCTCAAGCATGACCGGCCGCT
GCGCTTTCCCGACATCTCGTACAGCTTCTATCCGACCTACGCGCGCCTGTACGGCGTCGAGACCACGGTCGTGCCGCTCG
CGGACGACTTCTCGATCCGTGTCGAGGATTACCTCGACGACGCGGGCGGCGTGCTGTTTCCGAACCCGAACGCGCCGACC
GGGCGCGCGCTGCCGCTCGCGGACATCGAACGGATCGCGGCCGCGAACCCGTCGTCGGTCGTGCTGATCGACGAAGCGTA
TGTCGATTTCGGCGCGCAATCCGCGATCACGCTGATCGACCGCTATCCGAACCTGCTCGTCGTGCACACGACGTCGAAGG
CGCGCTCGCTCGCGGGCATGCGCGTCGGTTTCGCGTTCGGCGATGCGGCGCTGATCAACGCGCTCAATCGCGTAAAAGAC
AGCTTCAACTCGTATCCGCTCGACCGGCTCGCGCAGGCCGCCGCCCAGGCCGCATACGAAGACACCGACTATTTCAACGC
GACCTGCCGGCGTGTGATCGACACGCGTGCGCGGCTCACGCACGCGCTCGAGGCGCTCGGCTTCGACGTCGTGCCGTCGG
CCGCGAATTTCGTGTTCGCGCGCCACCCCGCGCACGATGCGGGCGCGATCGCGGCAAAGCTGAAGGATCGGGAAATTTTC
GTGCGGCACTTCCGCGCGCCGCGCATCGACCAGCACTTGCGCATCACCGTCGGCACCGACGCGGAATGCGACGCGCTCGT
CGCGGCGTTGCGCGAACTGATCGGCTGA

Upstream 100 bases:

>100_bases
CCGTGCGGCGGCGCCGGGCGGCCTCCCGGTCCTGTGCAATTGCGCACCCCGTCGCGCACATGCGGTAATCTGGTCGTTTT
TGCCCGTCAGGAGCCAAGCG

Downstream 100 bases:

>100_bases
AGCACAAGCGGGAAGCGGAACCGGCGCCGAGAGGCGCCGGTCGAGGAAATCGTGACGTCGTGACGCACGCGTCACGACGG
AGTCACTGCGGGGTCACGCT

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase 2 [H]

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MSRYWSDLVQQLVPYVPGEQPALAHPVKLNTNENPYPPSPRVVAAIARELGDTGDTLRRYPDPLARALRETVAAHHRIKP
EQVFVGNGSDEVLAHAFQALLKHDRPLRFPDISYSFYPTYARLYGVETTVVPLADDFSIRVEDYLDDAGGVLFPNPNAPT
GRALPLADIERIAAANPSSVVLIDEAYVDFGAQSAITLIDRYPNLLVVHTTSKARSLAGMRVGFAFGDAALINALNRVKD
SFNSYPLDRLAQAAAQAAYEDTDYFNATCRRVIDTRARLTHALEALGFDVVPSAANFVFARHPAHDAGAIAAKLKDREIF
VRHFRAPRIDQHLRITVGTDAECDALVAALRELIG

Sequences:

>Translated_355_residues
MSRYWSDLVQQLVPYVPGEQPALAHPVKLNTNENPYPPSPRVVAAIARELGDTGDTLRRYPDPLARALRETVAAHHRIKP
EQVFVGNGSDEVLAHAFQALLKHDRPLRFPDISYSFYPTYARLYGVETTVVPLADDFSIRVEDYLDDAGGVLFPNPNAPT
GRALPLADIERIAAANPSSVVLIDEAYVDFGAQSAITLIDRYPNLLVVHTTSKARSLAGMRVGFAFGDAALINALNRVKD
SFNSYPLDRLAQAAAQAAYEDTDYFNATCRRVIDTRARLTHALEALGFDVVPSAANFVFARHPAHDAGAIAAKLKDREIF
VRHFRAPRIDQHLRITVGTDAECDALVAALRELIG
>Mature_354_residues
SRYWSDLVQQLVPYVPGEQPALAHPVKLNTNENPYPPSPRVVAAIARELGDTGDTLRRYPDPLARALRETVAAHHRIKPE
QVFVGNGSDEVLAHAFQALLKHDRPLRFPDISYSFYPTYARLYGVETTVVPLADDFSIRVEDYLDDAGGVLFPNPNAPTG
RALPLADIERIAAANPSSVVLIDEAYVDFGAQSAITLIDRYPNLLVVHTTSKARSLAGMRVGFAFGDAALINALNRVKDS
FNSYPLDRLAQAAAQAAYEDTDYFNATCRRVIDTRARLTHALEALGFDVVPSAANFVFARHPAHDAGAIAAKLKDREIFV
RHFRAPRIDQHLRITVGTDAECDALVAALRELIG

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=355, Percent_Identity=31.830985915493, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1788722, Length=242, Percent_Identity=29.3388429752066, Blast_Score=68, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6322075, Length=363, Percent_Identity=28.6501377410468, Blast_Score=110, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 39036; Mature: 38904

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRYWSDLVQQLVPYVPGEQPALAHPVKLNTNENPYPPSPRVVAAIARELGDTGDTLRRY
CCHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHC
PDPLARALRETVAAHHRIKPEQVFVGNGSDEVLAHAFQALLKHDRPLRFPDISYSFYPTY
CCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCEECCHH
ARLYGVETTVVPLADDFSIRVEDYLDDAGGVLFPNPNAPTGRALPLADIERIAAANPSSV
HHHHCCCEEEEEECCCCEEEHHHHHCCCCCEEECCCCCCCCCCCCHHHHHHHHCCCCCCE
VLIDEAYVDFGAQSAITLIDRYPNLLVVHTTSKARSLAGMRVGFAFGDAALINALNRVKD
EEEEHHHHCCCCHHHHHHHHCCCCEEEEEECHHHHHHHHHEEEHHHHHHHHHHHHHHHHH
SFNSYPLDRLAQAAAQAAYEDTDYFNATCRRVIDTRARLTHALEALGFDVVPSAANFVFA
HHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
RHPAHDAGAIAAKLKDREIFVRHFRAPRIDQHLRITVGTDAECDALVAALRELIG
ECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHC
>Mature Secondary Structure 
SRYWSDLVQQLVPYVPGEQPALAHPVKLNTNENPYPPSPRVVAAIARELGDTGDTLRRY
CHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHC
PDPLARALRETVAAHHRIKPEQVFVGNGSDEVLAHAFQALLKHDRPLRFPDISYSFYPTY
CCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCEECCHH
ARLYGVETTVVPLADDFSIRVEDYLDDAGGVLFPNPNAPTGRALPLADIERIAAANPSSV
HHHHCCCEEEEEECCCCEEEHHHHHCCCCCEEECCCCCCCCCCCCHHHHHHHHCCCCCCE
VLIDEAYVDFGAQSAITLIDRYPNLLVVHTTSKARSLAGMRVGFAFGDAALINALNRVKD
EEEEHHHHCCCCHHHHHHHHCCCCEEEEEECHHHHHHHHHEEEHHHHHHHHHHHHHHHHH
SFNSYPLDRLAQAAAQAAYEDTDYFNATCRRVIDTRARLTHALEALGFDVVPSAANFVFA
HHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
RHPAHDAGAIAAKLKDREIFVRHFRAPRIDQHLRITVGTDAECDALVAALRELIG
ECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA