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The map label for this gene is glpK

Identifier: 115352782

GI number: 115352782

Start: 3008687

End: 3010189

Strand: Direct

Name: glpK

Synonym: Bamb_2731

Alternate gene names: 115352782

Gene position: 3008687-3010189 (Clockwise)

Preceding gene: 115352781

Following gene: 115352783

Centisome position: 84.6

GC content: 67.07

Gene sequence:

>1503_bases
ATGCAGGACCAGTACATCCTCGCGCTTGACCAGGGCACCACGAGTTCCCGCGCAATGCTGTTCGATCGCCAGGGCAATAT
CGTATCGATTGCCCAGAAGGAATTCGAACAGATCTACCCGCAACCCGGCTGGGTCGAGCACGACCCTCAGGAAATCTGGT
CGACACAGGCGGGCGTCGCGGCGGAAGCCGTCACGCGCACCGGCCTGAACGGCACGTCGATCGCCGCGATCGGCATCACC
AACCAGCGCGAGACGACGATCGTCTGGGATCGCGAGACGGGCCAGCCCGTCTACAACGCGATCGTCTGGCAGGACCGCCG
CACCGCCGACTTCTGCGATTCGCTGAAAAAGCAGGGCCTCGAGGCGAAGGTGCGCGCGAAGACCGGCCTGCCGATCGACT
CGTACTTCTCCGCGACGAAGATCCGCTGGATCCTCGACAACGTGCCGGGCGCGCGCGACAAGGCACGCCAGGGCAAGCTC
GCGTTCGGCACCGTCGACAGCTGGCTCGTGTGGAACTTCACGAAGCACGAGCTGCACGTGACCGACGTGACGAACGCGTC
GCGCACGATGCTGTTCAACATCCACACGCGCGAGTGGGACAGCGAGCTGCTCGAACTGCTCGACATCCCGCGCAGCATGC
TGCCGGACGTGAAGGCGTCGTCGGAAATCTACGGCCACACGAAAACCACCGTGTTCGCGTCGAAGATCCCGCTCGCGGGC
ATCGCCGGCGACCAGCACGCGGCGCTGTTCGGCCAGATGTGCACGACGTCGGGCATGGTGAAGAACACCTACGGCACTGG
CTGCTTCCTGATGATGAACACCGGCGACAAGCCGATCGAGTCGAAGAACAACCTCGTCACGACGATCGCCTGGCAGATCG
GCGACGACGTGCAGTACGCGCTCGAAGGCAGCATCTTCATCGCGGGCGCGGTCGTGCAGTGGCTGCGCGACGGCGTCGGC
ATCATCAAGACCGCCGCTGAAATCGAAGCGCTCGCCGCGAGCGTGCCGCATACCGACGGCGTCTATCTCGTGCCGGCGTT
CGCCGGCCTCGGTGCGCCGCACTGGAACGCGCGGGCGCGCGGTTCGGTGTTCGGCGTGACGCGCGGCACGACGTCCGCGC
ACCTCGCGCGCGCGGCGCTCGATGCGATCGCGTACCAGTCGCTCGACGTGCTGGCCGCGATGGAGGCCGACTCGGGCATC
AGCATCGGCGAGCTGCGCGTCGACGGCGGCGCGAGCGCGAACGACCTGCTGATGCAGTTCCAGGCCGACCTGCTCGGCGT
CGACGCGGTGCGTCCGCAGATCACCGAGACGACCGCGCTCGGCGCGGCCTACCTCGCCGGCCTCGCGATCGGCTACTGGA
AGAACCTCGACGAAGTGCGCAGCCAGTGGCAGCTCGATCGCCGCTTCGCGCCGTCGATGCCGAAGGAGCAGGTCGAGCAA
CGCATGGCCGGCTGGCAGCGCGCGGTGCGCGCCGCCAAGGCATGGGCCGACGACACGCAGTAA

Upstream 100 bases:

>100_bases
TTGCAGTTGCAGTTGTCTTACCGATGTTGATTCACCGACGCGCCGCCCGACATGCGGCGCGCATCACAACTACGCCGATC
CACGGATGGAGATGAGAGAC

Downstream 100 bases:

>100_bases
CCGCGGTACATCTAAACAAACGAAATACAACAACACCGGCGGACCGCGCGGCGCGCGAGTCCGCCGTCATCTACGAGAGA
CAACATGTCACCTTATATTG

Product: glycerol kinase

Products: NA

Alternate protein names: ATP:glycerol 3-phosphotransferase; Glycerokinase; GK [H]

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MQDQYILALDQGTTSSRAMLFDRQGNIVSIAQKEFEQIYPQPGWVEHDPQEIWSTQAGVAAEAVTRTGLNGTSIAAIGIT
NQRETTIVWDRETGQPVYNAIVWQDRRTADFCDSLKKQGLEAKVRAKTGLPIDSYFSATKIRWILDNVPGARDKARQGKL
AFGTVDSWLVWNFTKHELHVTDVTNASRTMLFNIHTREWDSELLELLDIPRSMLPDVKASSEIYGHTKTTVFASKIPLAG
IAGDQHAALFGQMCTTSGMVKNTYGTGCFLMMNTGDKPIESKNNLVTTIAWQIGDDVQYALEGSIFIAGAVVQWLRDGVG
IIKTAAEIEALAASVPHTDGVYLVPAFAGLGAPHWNARARGSVFGVTRGTTSAHLARAALDAIAYQSLDVLAAMEADSGI
SIGELRVDGGASANDLLMQFQADLLGVDAVRPQITETTALGAAYLAGLAIGYWKNLDEVRSQWQLDRRFAPSMPKEQVEQ
RMAGWQRAVRAAKAWADDTQ

Sequences:

>Translated_500_residues
MQDQYILALDQGTTSSRAMLFDRQGNIVSIAQKEFEQIYPQPGWVEHDPQEIWSTQAGVAAEAVTRTGLNGTSIAAIGIT
NQRETTIVWDRETGQPVYNAIVWQDRRTADFCDSLKKQGLEAKVRAKTGLPIDSYFSATKIRWILDNVPGARDKARQGKL
AFGTVDSWLVWNFTKHELHVTDVTNASRTMLFNIHTREWDSELLELLDIPRSMLPDVKASSEIYGHTKTTVFASKIPLAG
IAGDQHAALFGQMCTTSGMVKNTYGTGCFLMMNTGDKPIESKNNLVTTIAWQIGDDVQYALEGSIFIAGAVVQWLRDGVG
IIKTAAEIEALAASVPHTDGVYLVPAFAGLGAPHWNARARGSVFGVTRGTTSAHLARAALDAIAYQSLDVLAAMEADSGI
SIGELRVDGGASANDLLMQFQADLLGVDAVRPQITETTALGAAYLAGLAIGYWKNLDEVRSQWQLDRRFAPSMPKEQVEQ
RMAGWQRAVRAAKAWADDTQ
>Mature_500_residues
MQDQYILALDQGTTSSRAMLFDRQGNIVSIAQKEFEQIYPQPGWVEHDPQEIWSTQAGVAAEAVTRTGLNGTSIAAIGIT
NQRETTIVWDRETGQPVYNAIVWQDRRTADFCDSLKKQGLEAKVRAKTGLPIDSYFSATKIRWILDNVPGARDKARQGKL
AFGTVDSWLVWNFTKHELHVTDVTNASRTMLFNIHTREWDSELLELLDIPRSMLPDVKASSEIYGHTKTTVFASKIPLAG
IAGDQHAALFGQMCTTSGMVKNTYGTGCFLMMNTGDKPIESKNNLVTTIAWQIGDDVQYALEGSIFIAGAVVQWLRDGVG
IIKTAAEIEALAASVPHTDGVYLVPAFAGLGAPHWNARARGSVFGVTRGTTSAHLARAALDAIAYQSLDVLAAMEADSGI
SIGELRVDGGASANDLLMQFQADLLGVDAVRPQITETTALGAAYLAGLAIGYWKNLDEVRSQWQLDRRFAPSMPKEQVEQ
RMAGWQRAVRAAKAWADDTQ

Specific function: Key enzyme in the regulation of glycerol uptake and metabolism [H]

COG id: COG0554

COG function: function code C; Glycerol kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI189409120, Length=502, Percent_Identity=46.6135458167331, Blast_Score=455, Evalue=1e-128,
Organism=Homo sapiens, GI4504007, Length=501, Percent_Identity=46.7065868263473, Blast_Score=455, Evalue=1e-128,
Organism=Homo sapiens, GI42794763, Length=506, Percent_Identity=46.2450592885375, Blast_Score=454, Evalue=1e-127,
Organism=Homo sapiens, GI41393575, Length=501, Percent_Identity=44.9101796407186, Blast_Score=443, Evalue=1e-124,
Organism=Homo sapiens, GI88196792, Length=511, Percent_Identity=32.2896281800391, Blast_Score=309, Evalue=4e-84,
Organism=Escherichia coli, GI1790361, Length=497, Percent_Identity=58.5513078470825, Blast_Score=643, Evalue=0.0,
Organism=Escherichia coli, GI1790005, Length=501, Percent_Identity=25.1497005988024, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1789168, Length=495, Percent_Identity=25.4545454545455, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI1789987, Length=492, Percent_Identity=23.9837398373984, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1787789, Length=501, Percent_Identity=25.3493013972056, Blast_Score=92, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17535599, Length=500, Percent_Identity=43.8, Blast_Score=421, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI71986140, Length=515, Percent_Identity=23.495145631068, Blast_Score=168, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI71986147, Length=294, Percent_Identity=27.5510204081633, Blast_Score=117, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6321755, Length=555, Percent_Identity=35.1351351351351, Blast_Score=310, Evalue=2e-85,
Organism=Drosophila melanogaster, GI17864214, Length=508, Percent_Identity=41.9291338582677, Blast_Score=402, Evalue=1e-112,
Organism=Drosophila melanogaster, GI24655555, Length=478, Percent_Identity=42.0502092050209, Blast_Score=395, Evalue=1e-110,
Organism=Drosophila melanogaster, GI24655560, Length=478, Percent_Identity=42.0502092050209, Blast_Score=395, Evalue=1e-110,
Organism=Drosophila melanogaster, GI24655570, Length=478, Percent_Identity=42.0502092050209, Blast_Score=395, Evalue=1e-110,
Organism=Drosophila melanogaster, GI24655574, Length=478, Percent_Identity=42.0502092050209, Blast_Score=395, Evalue=1e-110,
Organism=Drosophila melanogaster, GI24655565, Length=478, Percent_Identity=42.0502092050209, Blast_Score=395, Evalue=1e-110,
Organism=Drosophila melanogaster, GI24654573, Length=448, Percent_Identity=42.4107142857143, Blast_Score=370, Evalue=1e-103,
Organism=Drosophila melanogaster, GI19922058, Length=527, Percent_Identity=33.2068311195446, Blast_Score=293, Evalue=2e-79,
Organism=Drosophila melanogaster, GI24652871, Length=494, Percent_Identity=34.0080971659919, Blast_Score=279, Evalue=4e-75,
Organism=Drosophila melanogaster, GI24656367, Length=514, Percent_Identity=31.3229571984436, Blast_Score=249, Evalue=3e-66,
Organism=Drosophila melanogaster, GI21357867, Length=526, Percent_Identity=30.4182509505703, Blast_Score=245, Evalue=4e-65,
Organism=Drosophila melanogaster, GI24656372, Length=358, Percent_Identity=31.5642458100559, Blast_Score=181, Evalue=8e-46,
Organism=Drosophila melanogaster, GI45552909, Length=298, Percent_Identity=29.1946308724832, Blast_Score=130, Evalue=2e-30,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR005999 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.30 [H]

Molecular weight: Translated: 54649; Mature: 54649

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDQYILALDQGTTSSRAMLFDRQGNIVSIAQKEFEQIYPQPGWVEHDPQEIWSTQAGVA
CCCCEEEEEECCCCCCEEEEEECCCCEEEHHHHHHHHHCCCCCCCCCCHHHHHCCCCCHH
AEAVTRTGLNGTSIAAIGITNQRETTIVWDRETGQPVYNAIVWQDRRTADFCDSLKKQGL
HHHHHHCCCCCCEEEEEEECCCCCEEEEEECCCCCHHHHHEEECCCCCHHHHHHHHHCCC
EAKVRAKTGLPIDSYFSATKIRWILDNVPGARDKARQGKLAFGTVDSWLVWNFTKHELHV
CEEEEECCCCCHHHHHCHHEEEEEECCCCCCCCHHHCCCEEEECCCCEEEEEEECCEEEE
TDVTNASRTMLFNIHTREWDSELLELLDIPRSMLPDVKASSEIYGHTKTTVFASKIPLAG
EECCCCCEEEEEEEECCHHHHHHHHHHHCCHHHCCCCCCCCHHCCCCEEEEEECCCCEEE
IAGDQHAALFGQMCTTSGMVKNTYGTGCFLMMNTGDKPIESKNNLVTTIAWQIGDDVQYA
CCCCCHHHHHHHHHHCCCCEECCCCCEEEEEECCCCCCCCCCCCEEEEEEEECCCCEEEE
LEGSIFIAGAVVQWLRDGVGIIKTAAEIEALAASVPHTDGVYLVPAFAGLGAPHWNARAR
ECCCEEEHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCCCCCCCCCCC
GSVFGVTRGTTSAHLARAALDAIAYQSLDVLAAMEADSGISIGELRVDGGASANDLLMQF
CCEEEEECCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEEEECCCCCHHHHHHHH
QADLLGVDAVRPQITETTALGAAYLAGLAIGYWKNLDEVRSQWQLDRRFAPSMPKEQVEQ
HHHHHCHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHH
RMAGWQRAVRAAKAWADDTQ
HHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQDQYILALDQGTTSSRAMLFDRQGNIVSIAQKEFEQIYPQPGWVEHDPQEIWSTQAGVA
CCCCEEEEEECCCCCCEEEEEECCCCEEEHHHHHHHHHCCCCCCCCCCHHHHHCCCCCHH
AEAVTRTGLNGTSIAAIGITNQRETTIVWDRETGQPVYNAIVWQDRRTADFCDSLKKQGL
HHHHHHCCCCCCEEEEEEECCCCCEEEEEECCCCCHHHHHEEECCCCCHHHHHHHHHCCC
EAKVRAKTGLPIDSYFSATKIRWILDNVPGARDKARQGKLAFGTVDSWLVWNFTKHELHV
CEEEEECCCCCHHHHHCHHEEEEEECCCCCCCCHHHCCCEEEECCCCEEEEEEECCEEEE
TDVTNASRTMLFNIHTREWDSELLELLDIPRSMLPDVKASSEIYGHTKTTVFASKIPLAG
EECCCCCEEEEEEEECCHHHHHHHHHHHCCHHHCCCCCCCCHHCCCCEEEEEECCCCEEE
IAGDQHAALFGQMCTTSGMVKNTYGTGCFLMMNTGDKPIESKNNLVTTIAWQIGDDVQYA
CCCCCHHHHHHHHHHCCCCEECCCCCEEEEEECCCCCCCCCCCCEEEEEEEECCCCEEEE
LEGSIFIAGAVVQWLRDGVGIIKTAAEIEALAASVPHTDGVYLVPAFAGLGAPHWNARAR
ECCCEEEHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCCCCCCCCCCC
GSVFGVTRGTTSAHLARAALDAIAYQSLDVLAAMEADSGISIGELRVDGGASANDLLMQF
CCEEEEECCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEEEECCCCCHHHHHHHH
QADLLGVDAVRPQITETTALGAAYLAGLAIGYWKNLDEVRSQWQLDRRFAPSMPKEQVEQ
HHHHHCHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHH
RMAGWQRAVRAAKAWADDTQ
HHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA