Click here to switch to the map view.

The map label for this gene is alsR [H]

Identifier: 115352249

GI number: 115352249

Start: 2423589

End: 2424491

Strand: Direct

Name: alsR [H]

Synonym: Bamb_2198

Alternate gene names: 115352249

Gene position: 2423589-2424491 (Clockwise)

Preceding gene: 115352245

Following gene: 115352263

Centisome position: 68.14

GC content: 68.99

Gene sequence:

>903_bases
ATGGAACTGCGGCAGTTGCGCTACTTCGTGGCGGTCGCCGAGGAACTGCATTTCGGGCGCGCGGCGAAGCGCCTGTTCAT
CTCGCAGCCGGCGCTGAGCTTCGACATCCGCAAGTTCGAGGAAGCGCTCGGCGTGCAGCTCTTTTCACGCACCAACAAGA
CAGTGGCGCTGACCAACGCGGGCGCGGTGCTGCTCGGCGAAGCGCGCCGGCTGCTGCTGCAGGCGAGCGAGGCCGAGCGT
CTCACGGTGCGCTCGGCGTCCGGTCTCGCGGGTCGCCTGCGGATCGGCTTCGTCCATTCGATGCTGTATCGCGGGCTGCC
CGATGCGGTGCAGCGCTTCGAGGCCGACTATCCGGGCGTGGAAATCGTGCTGAGCGAGATGAACACGCACGCGCAGGTGC
AGGCGGTCCAGCGCGGCCAGATCGATCTCGGTTACGCGCACTGGGGCCACTGCCCGCCCGAGGTCGAATCGACGCCCGTC
TACACGGAACCGTTCGTGTGCTGCCTGCCGGCCGCGCATCCGCTCGCGCGGCGGCGGCAGGTCGCGCTCGCCGCGCTGGC
CGCGGAACCGTTCATCCTGTTTCCGCGCGACGCGGCGCCGCACTATCACGACCTGATCATCGCGCAATGCGTGAACGCGG
GATTCAGCCCGCTGATCCGTCACGAGGCGCGGCTGTGGCAGACGATCCTGTCGATGATCGAGTTCGGGATGGGCATCGCG
CTGGTGCCGCGCGTGCTGCAGCAGGTGAAGAGCGACCGGCTCGCGTTCCGGCCGCTGAAGGATGCGTCGCTCGAATCGCG
CACGCTGGAACTGAAGCGCAGCGGCACCGCCGAACCGGTCGCGCTGCGCTTCGCCGACTACGTGCGCGCGTCGATCGACG
CGCTGCCGGCGCTCGCGGGCTGA

Upstream 100 bases:

>100_bases
GTTACGCAGAGCCTAGGCGCGTGATCGATAAGCGTCCAATACAGGATTTGTCCGGTACGATAGACGGCACTTATCGATGC
CGAAGCCGGGAGGAGACAGC

Downstream 100 bases:

>100_bases
GCAGGCACCGCTACTTCGCGTCAGGTTGCAGCACTGGTTGCGCGCGCCGGTACCACACCGCGTACACGACCGACAGCGCG
ATCAGGAACGGAATGCCGAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Als operon regulatory protein [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MELRQLRYFVAVAEELHFGRAAKRLFISQPALSFDIRKFEEALGVQLFSRTNKTVALTNAGAVLLGEARRLLLQASEAER
LTVRSASGLAGRLRIGFVHSMLYRGLPDAVQRFEADYPGVEIVLSEMNTHAQVQAVQRGQIDLGYAHWGHCPPEVESTPV
YTEPFVCCLPAAHPLARRRQVALAALAAEPFILFPRDAAPHYHDLIIAQCVNAGFSPLIRHEARLWQTILSMIEFGMGIA
LVPRVLQQVKSDRLAFRPLKDASLESRTLELKRSGTAEPVALRFADYVRASIDALPALAG

Sequences:

>Translated_300_residues
MELRQLRYFVAVAEELHFGRAAKRLFISQPALSFDIRKFEEALGVQLFSRTNKTVALTNAGAVLLGEARRLLLQASEAER
LTVRSASGLAGRLRIGFVHSMLYRGLPDAVQRFEADYPGVEIVLSEMNTHAQVQAVQRGQIDLGYAHWGHCPPEVESTPV
YTEPFVCCLPAAHPLARRRQVALAALAAEPFILFPRDAAPHYHDLIIAQCVNAGFSPLIRHEARLWQTILSMIEFGMGIA
LVPRVLQQVKSDRLAFRPLKDASLESRTLELKRSGTAEPVALRFADYVRASIDALPALAG
>Mature_300_residues
MELRQLRYFVAVAEELHFGRAAKRLFISQPALSFDIRKFEEALGVQLFSRTNKTVALTNAGAVLLGEARRLLLQASEAER
LTVRSASGLAGRLRIGFVHSMLYRGLPDAVQRFEADYPGVEIVLSEMNTHAQVQAVQRGQIDLGYAHWGHCPPEVESTPV
YTEPFVCCLPAAHPLARRRQVALAALAAEPFILFPRDAAPHYHDLIIAQCVNAGFSPLIRHEARLWQTILSMIEFGMGIA
LVPRVLQQVKSDRLAFRPLKDASLESRTLELKRSGTAEPVALRFADYVRASIDALPALAG

Specific function: Regulates the expression of the alsSD operon for acetoin biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=262, Percent_Identity=37.7862595419847, Blast_Score=178, Evalue=3e-46,
Organism=Escherichia coli, GI2367136, Length=263, Percent_Identity=36.8821292775665, Blast_Score=161, Evalue=5e-41,
Organism=Escherichia coli, GI1788887, Length=264, Percent_Identity=34.8484848484849, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI157672245, Length=302, Percent_Identity=31.1258278145695, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1790399, Length=243, Percent_Identity=30.4526748971193, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI145693105, Length=243, Percent_Identity=31.6872427983539, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1790208, Length=284, Percent_Identity=29.9295774647887, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1788748, Length=241, Percent_Identity=28.2157676348548, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787530, Length=246, Percent_Identity=26.0162601626016, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788481, Length=199, Percent_Identity=33.1658291457286, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1789173, Length=270, Percent_Identity=27.7777777777778, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787601, Length=159, Percent_Identity=32.0754716981132, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788296, Length=299, Percent_Identity=25.752508361204, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI87081904, Length=213, Percent_Identity=28.169014084507, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787806, Length=249, Percent_Identity=26.1044176706827, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788297, Length=153, Percent_Identity=30.0653594771242, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789204, Length=248, Percent_Identity=25.4032258064516, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI87082132, Length=144, Percent_Identity=28.4722222222222, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790262, Length=304, Percent_Identity=25.3289473684211, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI48994962, Length=72, Percent_Identity=44.4444444444444, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33245; Mature: 33245

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRQLRYFVAVAEELHFGRAAKRLFISQPALSFDIRKFEEALGVQLFSRTNKTVALTNA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECC
GAVLLGEARRLLLQASEAERLTVRSASGLAGRLRIGFVHSMLYRGLPDAVQRFEADYPGV
CCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCC
EIVLSEMNTHAQVQAVQRGQIDLGYAHWGHCPPEVESTPVYTEPFVCCLPAAHPLARRRQ
EEEEECCCCHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCHHEECCCCCHHHHHHH
VALAALAAEPFILFPRDAAPHYHDLIIAQCVNAGFSPLIRHEARLWQTILSMIEFGMGIA
HHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHH
LVPRVLQQVKSDRLAFRPLKDASLESRTLELKRSGTAEPVALRFADYVRASIDALPALAG
HHHHHHHHHHHCCEEECCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MELRQLRYFVAVAEELHFGRAAKRLFISQPALSFDIRKFEEALGVQLFSRTNKTVALTNA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECC
GAVLLGEARRLLLQASEAERLTVRSASGLAGRLRIGFVHSMLYRGLPDAVQRFEADYPGV
CCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCC
EIVLSEMNTHAQVQAVQRGQIDLGYAHWGHCPPEVESTPVYTEPFVCCLPAAHPLARRRQ
EEEEECCCCHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCHHEECCCCCHHHHHHH
VALAALAAEPFILFPRDAAPHYHDLIIAQCVNAGFSPLIRHEARLWQTILSMIEFGMGIA
HHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHH
LVPRVLQQVKSDRLAFRPLKDASLESRTLELKRSGTAEPVALRFADYVRASIDALPALAG
HHHHHHHHHHHCCEEECCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685336; 9353933; 9384377 [H]