Click here to switch to the map view.

The map label for this gene is mdtA [H]

Identifier: 115352148

GI number: 115352148

Start: 2305345

End: 2306520

Strand: Direct

Name: mdtA [H]

Synonym: Bamb_2097

Alternate gene names: 115352148

Gene position: 2305345-2306520 (Clockwise)

Preceding gene: 115352147

Following gene: 115352149

Centisome position: 64.82

GC content: 71.43

Gene sequence:

>1176_bases
ATGTCCACTGAATTCGACGTCCGTCCCCCCGCCACGCCGCGTTACCTGAAACCGCTCGCGATCGCCGGCGTGATCGCGGC
ACTCGCCGCCGCCGCGGCCGGCGTCGTCGAACGCGCGCACGATGCGCGTGAAGTCGCCGCGTGGACCGCCAGCCAGGCGA
TCCCGACCGTCGCGACGGTCGCGCCGCAGCCGGCCGCGGCCGATGCGCTGGTGCTGCCAGGCCGCCTCGACGCGTATGTC
GACGCGCCGATCTACGCGCGCGTGCCCGGCTACCTGCATGCGTGGTACGTCGACATCGGCGCGCACGTGAAGGCCGGCCA
GTTGCTCGCGTCGATCGACACGCCCGACCTCGACCAGCAGCTGCAGCAGGCGCGCGCCGACCTGCAAAGCGCGACGGCGA
ACGAACGGCTCGCGGCCGTCACCGCCGCGCGCTGGTCCGAGATGCTCGCGCAGGATTCGGTGTCGCGGCAGGAAGCCGAC
GAGAAGCGCAGCGATCTCGATGCGAAACGCGCGGCCGTGGCCGCCAGCACCGCGAACGTGCGTCGGCTCGAGGCGCTCGA
ATCGTTCAAGCGCCTCACCGCACCGTTCGACGGCGTCGTGACCGCGCGCAAGACCGATGTCGGCGCGCTGATCGACGCGG
GCAGCGGCAACGGCGCCGAACTCTTCACCGTCTCGGATGCACGGCGGCTGCGGCTCTACGTCCATATTCCGCAGGACGAC
GCGGGCGCGATCCGTGCGGGCATGCATGTCGCGCTGACCGTGCCCGAGCGTCCCGGCATGACGTTCGATGCGACGCTCGC
CGATTCCGCCCAGGCGATCGATCCGGCTTCCGGCACGCTGCTCGCGCAGTTCTCGATCGCGAACCCGGCAGGCACGCTGT
TCCCGGGCGAATACGCGCAGGTGCGGATCGCGGTGGCCAACGCCGCGCACGCGCTGACGATTCCGGCGAGCACACTGATC
TTCCGCCACGACGGGTTGCAGGTCGCCGTGCTCGACGCGACCGGGCATGCGCGCTTGCGCCACGTGTCGATCGCGACCGA
TCTCGGCACGCGCGTCGAGATCGCGTCGGGGCTCGCGGCGAGCGACCGCGTGATCGACAATCCGCCCGATTCGCTCGCGG
ACGGCGACCCGGTGCGCATCGCCGGCACCGCGACGAAGGAGCCTGCGCATGGCTGA

Upstream 100 bases:

>100_bases
GTCGCGACGCTCGTGTTCGTGCCCGTCGTGTTCAGCCTCGTCCATCGGCGCGACCGCGCGCCCCACTCCGAATCCCCGTC
CCTCACTCCGGGAGAACAGC

Downstream 100 bases:

>100_bases
CCGTACGCTCGCTGCATGGCTCGGCAGCGTCGCGCTGCTCGCCGGCTGTTCGTTCGCGCCGACGTATCACGCGCCGGCCG
TGCCGGTGCCGGCCGCGTTT

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MSTEFDVRPPATPRYLKPLAIAGVIAALAAAAAGVVERAHDAREVAAWTASQAIPTVATVAPQPAAADALVLPGRLDAYV
DAPIYARVPGYLHAWYVDIGAHVKAGQLLASIDTPDLDQQLQQARADLQSATANERLAAVTAARWSEMLAQDSVSRQEAD
EKRSDLDAKRAAVAASTANVRRLEALESFKRLTAPFDGVVTARKTDVGALIDAGSGNGAELFTVSDARRLRLYVHIPQDD
AGAIRAGMHVALTVPERPGMTFDATLADSAQAIDPASGTLLAQFSIANPAGTLFPGEYAQVRIAVANAAHALTIPASTLI
FRHDGLQVAVLDATGHARLRHVSIATDLGTRVEIASGLAASDRVIDNPPDSLADGDPVRIAGTATKEPAHG

Sequences:

>Translated_391_residues
MSTEFDVRPPATPRYLKPLAIAGVIAALAAAAAGVVERAHDAREVAAWTASQAIPTVATVAPQPAAADALVLPGRLDAYV
DAPIYARVPGYLHAWYVDIGAHVKAGQLLASIDTPDLDQQLQQARADLQSATANERLAAVTAARWSEMLAQDSVSRQEAD
EKRSDLDAKRAAVAASTANVRRLEALESFKRLTAPFDGVVTARKTDVGALIDAGSGNGAELFTVSDARRLRLYVHIPQDD
AGAIRAGMHVALTVPERPGMTFDATLADSAQAIDPASGTLLAQFSIANPAGTLFPGEYAQVRIAVANAAHALTIPASTLI
FRHDGLQVAVLDATGHARLRHVSIATDLGTRVEIASGLAASDRVIDNPPDSLADGDPVRIAGTATKEPAHG
>Mature_390_residues
STEFDVRPPATPRYLKPLAIAGVIAALAAAAAGVVERAHDAREVAAWTASQAIPTVATVAPQPAAADALVLPGRLDAYVD
APIYARVPGYLHAWYVDIGAHVKAGQLLASIDTPDLDQQLQQARADLQSATANERLAAVTAARWSEMLAQDSVSRQEADE
KRSDLDAKRAAVAASTANVRRLEALESFKRLTAPFDGVVTARKTDVGALIDAGSGNGAELFTVSDARRLRLYVHIPQDDA
GAIRAGMHVALTVPERPGMTFDATLADSAQAIDPASGTLLAQFSIANPAGTLFPGEYAQVRIAVANAAHALTIPASTLIF
RHDGLQVAVLDATGHARLRHVSIATDLGTRVEIASGLAASDRVIDNPPDSLADGDPVRIAGTATKEPAHG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=332, Percent_Identity=27.1084337349398, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI87081796, Length=341, Percent_Identity=28.1524926686217, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789929, Length=337, Percent_Identity=27.299703264095, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1789665, Length=307, Percent_Identity=26.0586319218241, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786668, Length=337, Percent_Identity=26.1127596439169, Blast_Score=73, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 40816; Mature: 40685

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTEFDVRPPATPRYLKPLAIAGVIAALAAAAAGVVERAHDAREVAAWTASQAIPTVATV
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
APQPAAADALVLPGRLDAYVDAPIYARVPGYLHAWYVDIGAHVKAGQLLASIDTPDLDQQ
CCCCCCCCEEEECCCCCEEECCCEEEECCCCEEEEEEEECCCEECCCEEEECCCCCHHHH
LQQARADLQSATANERLAAVTAARWSEMLAQDSVSRQEADEKRSDLDAKRAAVAASTANV
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
RRLEALESFKRLTAPFDGVVTARKTDVGALIDAGSGNGAELFTVSDARRLRLYVHIPQDD
HHHHHHHHHHHHCCCCCCEEEEECCCCCEEEECCCCCCEEEEEECCCEEEEEEEEECCCC
AGAIRAGMHVALTVPERPGMTFDATLADSAQAIDPASGTLLAQFSIANPAGTLFPGEYAQ
CCHHCCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCEE
VRIAVANAAHALTIPASTLIFRHDGLQVAVLDATGHARLRHVSIATDLGTRVEIASGLAA
EEEEEECCCEEEEECCEEEEEEECCCEEEEEECCCCCEEEEEEEECCCCCEEEHHCCCCC
SDRVIDNPPDSLADGDPVRIAGTATKEPAHG
CCCCCCCCCCCCCCCCCEEEEECCCCCCCCC
>Mature Secondary Structure 
STEFDVRPPATPRYLKPLAIAGVIAALAAAAAGVVERAHDAREVAAWTASQAIPTVATV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
APQPAAADALVLPGRLDAYVDAPIYARVPGYLHAWYVDIGAHVKAGQLLASIDTPDLDQQ
CCCCCCCCEEEECCCCCEEECCCEEEECCCCEEEEEEEECCCEECCCEEEECCCCCHHHH
LQQARADLQSATANERLAAVTAARWSEMLAQDSVSRQEADEKRSDLDAKRAAVAASTANV
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
RRLEALESFKRLTAPFDGVVTARKTDVGALIDAGSGNGAELFTVSDARRLRLYVHIPQDD
HHHHHHHHHHHHCCCCCCEEEEECCCCCEEEECCCCCCEEEEEECCCEEEEEEEEECCCC
AGAIRAGMHVALTVPERPGMTFDATLADSAQAIDPASGTLLAQFSIANPAGTLFPGEYAQ
CCHHCCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCEE
VRIAVANAAHALTIPASTLIFRHDGLQVAVLDATGHARLRHVSIATDLGTRVEIASGLAA
EEEEEECCCEEEEECCEEEEEEECCCEEEEEECCCCCEEEEEEEECCCCCEEEHHCCCCC
SDRVIDNPPDSLADGDPVRIAGTATKEPAHG
CCCCCCCCCCCCCCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA