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The map label for this gene is rnr [H]

Identifier: 115351500

GI number: 115351500

Start: 1595979

End: 1598432

Strand: Direct

Name: rnr [H]

Synonym: Bamb_1447

Alternate gene names: 115351500

Gene position: 1595979-1598432 (Clockwise)

Preceding gene: 115351499

Following gene: 115351501

Centisome position: 44.87

GC content: 67.28

Gene sequence:

>2454_bases
TTGAGCAAATATCCGTACCCCATTCCGAGCCGTGAAGAAATTCTCGGCGTGCTGCGTACGAGCGACGCGCCGCTGGCCGC
CAACGACATCGCCGAAGCGCTGTCGATCAAGCGCCAGGAACGCGAGGGGTTCTTCCGGCGTGTCGCCGCAATGGAACGCG
ACGGCCAGATCCGCCTCGACAAGCGCGGCCACTACCAGCTCACTCATCCGTCGAACTTCGTTGCCGGTCGCGTGCAAGGG
CATCGCGACGGCTACGGCTTCGTGATCCGCGACGACGGCCAGGACGACCTGTTCTTGCCGAACGGCGAGATGCAGAAGGT
GATGCACAACGACCGCGTGCTCGCGCGGATCGTCGGCTACGATCGCCGCGGCCGGCCGGAAGGCCATGTGGTCGAGGTCA
CCGAGCGCGCGAACAAGCGCGTGATCGGCCGCCTGCTCAACGAGAACGGCGCGCTGATCGTCGCGCCCGAAGACAAGCGC
ATCGGCCACGACATCCTGATCACGCAGAACGTGAAGAAGGCGAAGGTCGGGCAGGTCGTCGTCGTCGAACTGACCGACTT
CCCGAGCCGCCATTCGCAACCGCTCGGCCGCGTCGTCGAAGTGCTCGGCGACATCGACGATCCGGGCATGGAAATCGAGA
TCGCCGTGCGCAAGTACGGCGTGCCGCACGAATTCGGCCAGCGGGCGCTCGACGATGCCGCCGCGCTGCCGGACGCGGTA
CGTCCGGCCGACCTGCGCTTCCGCGTCGATTTGCGCGACGTGCCGCTCGTGACGATCGACGGCGAGGACGCCCGCGACTT
CGACGATGCCGTCTACTGCGAACCGACCAAGGTCGGTCGCGGCGACGGTTACCGCCTGATCGTCGCGATCGCCGACGTGT
CGCACTACGTGCAGCCGGGCAGCGGCCTCGATGCCGACGCGCTGGAGCGCAGCACGTCGGTCTATTTCCCGCGCCGCGTG
ATCCCGATGCTGCCGGAGAAGCTGTCGAACGGGCTGTGCTCGCTGAATCCGCAGGTCGACCGCTGCGTGCTCGTGTGCGA
CATGGTGATTACCGCGCGCGGCGAGATCAAGGCGTACCAGTTCTATCCGGCGGTCATCCATTCGGCCGCGCGCCTGACGT
ACACCGAAGTCGCGGCCGTGCTGTCGAACACGAAGGGGCCGGAGGCCGCGCGCCGCGCGGACCTGCTGCCGCACCTGCAG
GATCTGTACGGCGTCTACAAGTCGCTGTTCGCTGCACGCCAGAAGCGCGGCGCGATTGATTTCGACACGACCGAGACGTA
CATCGTCTGCAACTCGCAGGGCAAGATCGAACAGATCGTGCCGCGTCAGCGCAACGATGCGCACAAGCTGATCGAGGAAT
GCATGCTGGCCGCGAACGTCTGCGCGGCCGACTTCCTGAAGCGCAACAAGCATGCGGGCCTGTACCGCGTGCACGCGGGG
CCGACGCCGGAAAAGCTCGAGAACCTGCGCGCGTTCCTGCGCGGCATGGGCCTGTCGCTCGGCGGCGGCGAGAAGCCGCA
TGCGAGCGACTATGCGGCGCTGATGGCGCAGATTCGCGACCGGCCCGACGCGCAGATGCTGCAGCCGATGCTGCTGCGCT
CGATGCAGCAGGCCGTCTACAGCCCGGACAACATCGGCCACTTCGGTCTCGCGTATGAGGCGTACGCGCACTTCACGAGC
CCGATCCGCCGCTATCCCGACCTGCTCACGCACCGCGCGATCTACGCGATCCTGTCGGGCAAGAAGTACACGCCGAAGGC
GCCGGACGGCTTCGAGCTGAACACCGCGCTGTCGCCGCGCGCCCGCGCGATGCAGCAGGCCGACGACGAAGCGCGCGGCC
GGTCGCGCGTGAACACCGCGATCTGGGAAGAACTCGGCCTGCATTGCTCGGCGAACGAGCGGCGTGCCGACGAAGCGTCG
CGCGACGTCGAGGCCTGGCTCAAGTGCTACTTCATGCGCGACAAGCTCGGCGAGGAATACGGCGGGATGGTGAACGGCGT
CACGTCGTTCGGCATCTTCGTGCAACTCGACACGCTGTTCATCGAAGGGCTCGTGCACGTCACGGAACTCGGCTCGGACT
ACTTCCAGTACGACGAGATCAAGAACGAGCTGCGCGGCGAGCGCACGGGCATCCGTTATCGCCTGTCGGATCGCGTGCGC
GTGCAGGTGAGCCGCGTCGATCTCGATGCGCGCAAGATCGACTTCCGCCTGGTGCGCGACACGCCGGTGAAGGCGCCGCG
TCCCGCACCGGCGCCGGTTGCTGTCGGCAACGGTAACGATCGCGGCGGCCCGCGCGTGCGCTCGTTGCCGCCGGCGGAAG
ACGCCGCGCCGCGCCGCAAGCGGACGGCCAGCGCACCGACCGCCGCGGTGAACGACACGCGTGCGGCGAAGAAGAAGGGC
GGCGCGCCGGCGAAGACGGCCGCGAAGAAGACACACGCCCGCAAGAAGTATTGA

Upstream 100 bases:

>100_bases
AATGACCCGCCGCCGTCACTATAGAACTGTCTGACGGACACTTCTATGTTGATGCCGTGCACCATCAGTCAACGCAACGA
GAACAATCATCGACAAACCC

Downstream 100 bases:

>100_bases
GCGTTCGGGGCGGCGCATGCGCACGCCCTTGCAGTATCGAGAGACGCCGCGTTCTACCGGTCATCGGCCGGCAACGCGGC
GCTTTCCTTTTCCATGGATC

Product: ribonuclease R

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 817; Mature: 816

Protein sequence:

>817_residues
MSKYPYPIPSREEILGVLRTSDAPLAANDIAEALSIKRQEREGFFRRVAAMERDGQIRLDKRGHYQLTHPSNFVAGRVQG
HRDGYGFVIRDDGQDDLFLPNGEMQKVMHNDRVLARIVGYDRRGRPEGHVVEVTERANKRVIGRLLNENGALIVAPEDKR
IGHDILITQNVKKAKVGQVVVVELTDFPSRHSQPLGRVVEVLGDIDDPGMEIEIAVRKYGVPHEFGQRALDDAAALPDAV
RPADLRFRVDLRDVPLVTIDGEDARDFDDAVYCEPTKVGRGDGYRLIVAIADVSHYVQPGSGLDADALERSTSVYFPRRV
IPMLPEKLSNGLCSLNPQVDRCVLVCDMVITARGEIKAYQFYPAVIHSAARLTYTEVAAVLSNTKGPEAARRADLLPHLQ
DLYGVYKSLFAARQKRGAIDFDTTETYIVCNSQGKIEQIVPRQRNDAHKLIEECMLAANVCAADFLKRNKHAGLYRVHAG
PTPEKLENLRAFLRGMGLSLGGGEKPHASDYAALMAQIRDRPDAQMLQPMLLRSMQQAVYSPDNIGHFGLAYEAYAHFTS
PIRRYPDLLTHRAIYAILSGKKYTPKAPDGFELNTALSPRARAMQQADDEARGRSRVNTAIWEELGLHCSANERRADEAS
RDVEAWLKCYFMRDKLGEEYGGMVNGVTSFGIFVQLDTLFIEGLVHVTELGSDYFQYDEIKNELRGERTGIRYRLSDRVR
VQVSRVDLDARKIDFRLVRDTPVKAPRPAPAPVAVGNGNDRGGPRVRSLPPAEDAAPRRKRTASAPTAAVNDTRAAKKKG
GAPAKTAAKKTHARKKY

Sequences:

>Translated_817_residues
MSKYPYPIPSREEILGVLRTSDAPLAANDIAEALSIKRQEREGFFRRVAAMERDGQIRLDKRGHYQLTHPSNFVAGRVQG
HRDGYGFVIRDDGQDDLFLPNGEMQKVMHNDRVLARIVGYDRRGRPEGHVVEVTERANKRVIGRLLNENGALIVAPEDKR
IGHDILITQNVKKAKVGQVVVVELTDFPSRHSQPLGRVVEVLGDIDDPGMEIEIAVRKYGVPHEFGQRALDDAAALPDAV
RPADLRFRVDLRDVPLVTIDGEDARDFDDAVYCEPTKVGRGDGYRLIVAIADVSHYVQPGSGLDADALERSTSVYFPRRV
IPMLPEKLSNGLCSLNPQVDRCVLVCDMVITARGEIKAYQFYPAVIHSAARLTYTEVAAVLSNTKGPEAARRADLLPHLQ
DLYGVYKSLFAARQKRGAIDFDTTETYIVCNSQGKIEQIVPRQRNDAHKLIEECMLAANVCAADFLKRNKHAGLYRVHAG
PTPEKLENLRAFLRGMGLSLGGGEKPHASDYAALMAQIRDRPDAQMLQPMLLRSMQQAVYSPDNIGHFGLAYEAYAHFTS
PIRRYPDLLTHRAIYAILSGKKYTPKAPDGFELNTALSPRARAMQQADDEARGRSRVNTAIWEELGLHCSANERRADEAS
RDVEAWLKCYFMRDKLGEEYGGMVNGVTSFGIFVQLDTLFIEGLVHVTELGSDYFQYDEIKNELRGERTGIRYRLSDRVR
VQVSRVDLDARKIDFRLVRDTPVKAPRPAPAPVAVGNGNDRGGPRVRSLPPAEDAAPRRKRTASAPTAAVNDTRAAKKKG
GAPAKTAAKKTHARKKY
>Mature_816_residues
SKYPYPIPSREEILGVLRTSDAPLAANDIAEALSIKRQEREGFFRRVAAMERDGQIRLDKRGHYQLTHPSNFVAGRVQGH
RDGYGFVIRDDGQDDLFLPNGEMQKVMHNDRVLARIVGYDRRGRPEGHVVEVTERANKRVIGRLLNENGALIVAPEDKRI
GHDILITQNVKKAKVGQVVVVELTDFPSRHSQPLGRVVEVLGDIDDPGMEIEIAVRKYGVPHEFGQRALDDAAALPDAVR
PADLRFRVDLRDVPLVTIDGEDARDFDDAVYCEPTKVGRGDGYRLIVAIADVSHYVQPGSGLDADALERSTSVYFPRRVI
PMLPEKLSNGLCSLNPQVDRCVLVCDMVITARGEIKAYQFYPAVIHSAARLTYTEVAAVLSNTKGPEAARRADLLPHLQD
LYGVYKSLFAARQKRGAIDFDTTETYIVCNSQGKIEQIVPRQRNDAHKLIEECMLAANVCAADFLKRNKHAGLYRVHAGP
TPEKLENLRAFLRGMGLSLGGGEKPHASDYAALMAQIRDRPDAQMLQPMLLRSMQQAVYSPDNIGHFGLAYEAYAHFTSP
IRRYPDLLTHRAIYAILSGKKYTPKAPDGFELNTALSPRARAMQQADDEARGRSRVNTAIWEELGLHCSANERRADEASR
DVEAWLKCYFMRDKLGEEYGGMVNGVTSFGIFVQLDTLFIEGLVHVTELGSDYFQYDEIKNELRGERTGIRYRLSDRVRV
QVSRVDLDARKIDFRLVRDTPVKAPRPAPAPVAVGNGNDRGGPRVRSLPPAEDAAPRRKRTASAPTAAVNDTRAAKKKGG
APAKTAAKKTHARKKY

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014625, Length=488, Percent_Identity=29.5081967213115, Blast_Score=196, Evalue=6e-50,
Organism=Homo sapiens, GI190014623, Length=488, Percent_Identity=29.5081967213115, Blast_Score=196, Evalue=8e-50,
Organism=Homo sapiens, GI134288890, Length=440, Percent_Identity=30.4545454545455, Blast_Score=170, Evalue=6e-42,
Organism=Homo sapiens, GI19115966, Length=648, Percent_Identity=25.6172839506173, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI219521928, Length=648, Percent_Identity=25.6172839506173, Blast_Score=151, Evalue=2e-36,
Organism=Escherichia coli, GI87082383, Length=749, Percent_Identity=48.4646194926569, Blast_Score=685, Evalue=0.0,
Organism=Escherichia coli, GI1787542, Length=699, Percent_Identity=27.6108726752504, Blast_Score=201, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI212645896, Length=416, Percent_Identity=30.5288461538462, Blast_Score=181, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17553506, Length=532, Percent_Identity=28.7593984962406, Blast_Score=162, Evalue=6e-40,
Organism=Saccharomyces cerevisiae, GI6324552, Length=654, Percent_Identity=25.6880733944954, Blast_Score=145, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24649634, Length=517, Percent_Identity=27.852998065764, Blast_Score=182, Evalue=9e-46,
Organism=Drosophila melanogaster, GI24654592, Length=434, Percent_Identity=29.4930875576037, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI19922976, Length=434, Percent_Identity=29.4930875576037, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24654597, Length=434, Percent_Identity=29.4930875576037, Blast_Score=148, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805
- InterPro:   IPR013668 [H]

Pfam domain/function: PF08461 HTH_12; PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 90980; Mature: 90849

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKYPYPIPSREEILGVLRTSDAPLAANDIAEALSIKRQEREGFFRRVAAMERDGQIRLD
CCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
KRGHYQLTHPSNFVAGRVQGHRDGYGFVIRDDGQDDLFLPNGEMQKVMHNDRVLARIVGY
CCCCEEEECCCCCEEECCCCCCCCEEEEEEECCCCCEECCCCHHHHHHHCCHHHHHHHCC
DRRGRPEGHVVEVTERANKRVIGRLLNENGALIVAPEDKRIGHDILITQNVKKAKVGQVV
CCCCCCCCCEEEEHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEECCCCHHCCCCEE
VVELTDFPSRHSQPLGRVVEVLGDIDDPGMEIEIAVRKYGVPHEFGQRALDDAAALPDAV
EEEECCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCC
RPADLRFRVDLRDVPLVTIDGEDARDFDDAVYCEPTKVGRGDGYRLIVAIADVSHYVQPG
CCCCEEEEEEECCCCEEEECCCCCCCCCCCEEECCCCCCCCCCCEEEEEEECHHHHCCCC
SGLDADALERSTSVYFPRRVIPMLPEKLSNGLCSLNPQVDRCVLVCDMVITARGEIKAYQ
CCCCHHHHHCCCCCCCCHHHHHHCHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEE
FYPAVIHSAARLTYTEVAAVLSNTKGPEAARRADLLPHLQDLYGVYKSLFAARQKRGAID
EHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FDTTETYIVCNSQGKIEQIVPRQRNDAHKLIEECMLAANVCAADFLKRNKHAGLYRVHAG
CCCCCEEEEECCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
PTPEKLENLRAFLRGMGLSLGGGEKPHASDYAALMAQIRDRPDAQMLQPMLLRSMQQAVY
CCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
SPDNIGHFGLAYEAYAHFTSPIRRYPDLLTHRAIYAILSGKKYTPKAPDGFELNTALSPR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCHH
ARAMQQADDEARGRSRVNTAIWEELGLHCSANERRADEASRDVEAWLKCYFMRDKLGEEY
HHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHH
GGMVNGVTSFGIFVQLDTLFIEGLVHVTELGSDYFQYDEIKNELRGERTGIRYRLSDRVR
CCHHHCHHHHEEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCCEE
VQVSRVDLDARKIDFRLVRDTPVKAPRPAPAPVAVGNGNDRGGPRVRSLPPAEDAAPRRK
EEEEEECCCCCEEEEEEEECCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCHHH
RTASAPTAAVNDTRAAKKKGGAPAKTAAKKTHARKKY
HCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
SKYPYPIPSREEILGVLRTSDAPLAANDIAEALSIKRQEREGFFRRVAAMERDGQIRLD
CCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
KRGHYQLTHPSNFVAGRVQGHRDGYGFVIRDDGQDDLFLPNGEMQKVMHNDRVLARIVGY
CCCCEEEECCCCCEEECCCCCCCCEEEEEEECCCCCEECCCCHHHHHHHCCHHHHHHHCC
DRRGRPEGHVVEVTERANKRVIGRLLNENGALIVAPEDKRIGHDILITQNVKKAKVGQVV
CCCCCCCCCEEEEHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEECCCCHHCCCCEE
VVELTDFPSRHSQPLGRVVEVLGDIDDPGMEIEIAVRKYGVPHEFGQRALDDAAALPDAV
EEEECCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCC
RPADLRFRVDLRDVPLVTIDGEDARDFDDAVYCEPTKVGRGDGYRLIVAIADVSHYVQPG
CCCCEEEEEEECCCCEEEECCCCCCCCCCCEEECCCCCCCCCCCEEEEEEECHHHHCCCC
SGLDADALERSTSVYFPRRVIPMLPEKLSNGLCSLNPQVDRCVLVCDMVITARGEIKAYQ
CCCCHHHHHCCCCCCCCHHHHHHCHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEE
FYPAVIHSAARLTYTEVAAVLSNTKGPEAARRADLLPHLQDLYGVYKSLFAARQKRGAID
EHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FDTTETYIVCNSQGKIEQIVPRQRNDAHKLIEECMLAANVCAADFLKRNKHAGLYRVHAG
CCCCCEEEEECCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
PTPEKLENLRAFLRGMGLSLGGGEKPHASDYAALMAQIRDRPDAQMLQPMLLRSMQQAVY
CCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
SPDNIGHFGLAYEAYAHFTSPIRRYPDLLTHRAIYAILSGKKYTPKAPDGFELNTALSPR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCHH
ARAMQQADDEARGRSRVNTAIWEELGLHCSANERRADEASRDVEAWLKCYFMRDKLGEEY
HHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHH
GGMVNGVTSFGIFVQLDTLFIEGLVHVTELGSDYFQYDEIKNELRGERTGIRYRLSDRVR
CCHHHCHHHHEEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCCEE
VQVSRVDLDARKIDFRLVRDTPVKAPRPAPAPVAVGNGNDRGGPRVRSLPPAEDAAPRRK
EEEEEECCCCCEEEEEEEECCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCHHH
RTASAPTAAVNDTRAAKKKGGAPAKTAAKKTHARKKY
HCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]