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The map label for this gene is insK [H]

Identifier: 115351499

GI number: 115351499

Start: 1594594

End: 1595430

Strand: Direct

Name: insK [H]

Synonym: Bamb_1446

Alternate gene names: 115351499

Gene position: 1594594-1595430 (Clockwise)

Preceding gene: 115351498

Following gene: 115351500

Centisome position: 44.84

GC content: 57.95

Gene sequence:

>837_bases
GTGCACGAGCTTAGGCAGCACCATCCGGTAGCGGCACTTCTGAAGGCGGCCGGCTTGGCGCGTAGCACGTTCTATTACCA
GCTTGGGACGCTGAGCGTCGACGATCGCCGTGCCGATCTCAAGGCGAAGATCCGGGCGGTGTTCGACCATCACAAGGGCC
GCTACGGCTATCGACGCGTCACGGCTGCGATTCGGCAAACCGGGCATCTCGTCAACCACAAGGCCGTGCAGAGGCTGATG
CAGCAATTGCAGTTGAAATCCCTGCTGCGCCCGAAGAAATACCGCTCCTGGCGAGGCGAAGTCGGCAAAGCCGCACCCAA
CCTGCTGCAACGTCAGTTTAGTGCCGCACAGGCCAATCAGAAGTGGGTGACGGATGTGACGGAATTCAACGTCGGCGGTC
AGAAGCTGTACCTGTCGCCGGTGATGGATCTGTACAACGGCGAGATCGTGGCTTACCAGATGGATCGACGCCCAAGCTTC
GAGTTGGTCAGCGGCATGCTCAAGAAGGCGCTGACCAAACTCAAACGCACGGACAGACCGCTATTGCATTCGGACCAAGG
CTGGCAATACCGAATGCCGGCGTTTCGCCGGCAACTGAAGCGGCGCAAACTGACTCAAAGCATGTCCCGCAAGGGGAACT
GCCTCGATAATGCTGCGATGGAAAGCTTCTTCGGCACGCTCAAGTCCGAGTGCTACAAGGGACATCGCTTCACTTGCGTG
GAGCATTTGCGCGACACGCTCAATCACTACATCCACTACTACAACCACGAACGCATCAAGCTCAAATTGAAAGGGCTGAG
TCCCGTGCAATACAGAACTCAGCCCTTGAGCGCCTAG

Upstream 100 bases:

>100_bases
TCAAGGAAAACGAGTATTTGCGTGCGGAGGTGGCCTACCTAAAAAAGCTCGATGCGCTGCTGGCGAAGAAGCAGGCAGCG
CAAAAGAAAAAGCGCAAATA

Downstream 100 bases:

>100_bases
CCTTCAACTGTCCAACTTTGCGGGGTCAGTTCAGAAGCCGACCTTTTCAAAAACAGATGGTGCCCAGGAGAGGACTCGGT
CACACAAGCGCGACCCCGGC

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MHELRQHHPVAALLKAAGLARSTFYYQLGTLSVDDRRADLKAKIRAVFDHHKGRYGYRRVTAAIRQTGHLVNHKAVQRLM
QQLQLKSLLRPKKYRSWRGEVGKAAPNLLQRQFSAAQANQKWVTDVTEFNVGGQKLYLSPVMDLYNGEIVAYQMDRRPSF
ELVSGMLKKALTKLKRTDRPLLHSDQGWQYRMPAFRRQLKRRKLTQSMSRKGNCLDNAAMESFFGTLKSECYKGHRFTCV
EHLRDTLNHYIHYYNHERIKLKLKGLSPVQYRTQPLSA

Sequences:

>Translated_278_residues
MHELRQHHPVAALLKAAGLARSTFYYQLGTLSVDDRRADLKAKIRAVFDHHKGRYGYRRVTAAIRQTGHLVNHKAVQRLM
QQLQLKSLLRPKKYRSWRGEVGKAAPNLLQRQFSAAQANQKWVTDVTEFNVGGQKLYLSPVMDLYNGEIVAYQMDRRPSF
ELVSGMLKKALTKLKRTDRPLLHSDQGWQYRMPAFRRQLKRRKLTQSMSRKGNCLDNAAMESFFGTLKSECYKGHRFTCV
EHLRDTLNHYIHYYNHERIKLKLKGLSPVQYRTQPLSA
>Mature_278_residues
MHELRQHHPVAALLKAAGLARSTFYYQLGTLSVDDRRADLKAKIRAVFDHHKGRYGYRRVTAAIRQTGHLVNHKAVQRLM
QQLQLKSLLRPKKYRSWRGEVGKAAPNLLQRQFSAAQANQKWVTDVTEFNVGGQKLYLSPVMDLYNGEIVAYQMDRRPSF
ELVSGMLKKALTKLKRTDRPLLHSDQGWQYRMPAFRRQLKRRKLTQSMSRKGNCLDNAAMESFFGTLKSECYKGHRFTCV
EHLRDTLNHYIHYYNHERIKLKLKGLSPVQYRTQPLSA

Specific function: Involved in the transposition of the insertion sequence IS150 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=238, Percent_Identity=28.5714285714286, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1789981, Length=274, Percent_Identity=55.1094890510949, Blast_Score=330, Evalue=5e-92,
Organism=Escherichia coli, GI1788405, Length=274, Percent_Identity=33.2116788321168, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1787263, Length=274, Percent_Identity=33.2116788321168, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1786753, Length=274, Percent_Identity=33.2116788321168, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1786570, Length=274, Percent_Identity=33.2116788321168, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1786490, Length=274, Percent_Identity=33.2116788321168, Blast_Score=135, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 32410; Mature: 32410

Theoretical pI: Translated: 10.98; Mature: 10.98

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHELRQHHPVAALLKAAGLARSTFYYQLGTLSVDDRRADLKAKIRAVFDHHKGRYGYRRV
CCCHHHHCHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHH
TAAIRQTGHLVNHKAVQRLMQQLQLKSLLRPKKYRSWRGEVGKAAPNLLQRQFSAAQANQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCC
KWVTDVTEFNVGGQKLYLSPVMDLYNGEIVAYQMDRRPSFELVSGMLKKALTKLKRTDRP
HHHHHHHHCCCCCCEEEHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCC
LLHSDQGWQYRMPAFRRQLKRRKLTQSMSRKGNCLDNAAMESFFGTLKSECYKGHRFTCV
CCCCCCCCEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
EHLRDTLNHYIHYYNHERIKLKLKGLSPVQYRTQPLSA
HHHHHHHHHHHHHHCCCEEEEEECCCCCCHHCCCCCCC
>Mature Secondary Structure
MHELRQHHPVAALLKAAGLARSTFYYQLGTLSVDDRRADLKAKIRAVFDHHKGRYGYRRV
CCCHHHHCHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHH
TAAIRQTGHLVNHKAVQRLMQQLQLKSLLRPKKYRSWRGEVGKAAPNLLQRQFSAAQANQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCC
KWVTDVTEFNVGGQKLYLSPVMDLYNGEIVAYQMDRRPSFELVSGMLKKALTKLKRTDRP
HHHHHHHHCCCCCCEEEHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCC
LLHSDQGWQYRMPAFRRQLKRRKLTQSMSRKGNCLDNAAMESFFGTLKSECYKGHRFTCV
CCCCCCCCEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
EHLRDTLNHYIHYYNHERIKLKLKGLSPVQYRTQPLSA
HHHHHHHHHHHHHHCCCEEEEEECCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2841644; 2541046; 8041620; 9278503 [H]