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The map label for this gene is iorA [H]

Identifier: 115351128

GI number: 115351128

Start: 1167943

End: 1168383

Strand: Direct

Name: iorA [H]

Synonym: Bamb_1074

Alternate gene names: 115351128

Gene position: 1167943-1168383 (Clockwise)

Preceding gene: 115351126

Following gene: 115351129

Centisome position: 32.84

GC content: 69.39

Gene sequence:

>441_bases
ATGCGCTTCACGCTGAACGGCCAGCCGTTCGATTTCGACGGCGATCCCGATACGCCGCTGCTGTGGGTCATTCGCGACTC
GGCCCGCCTCACCGGCACCAAATACGGCTGCGGCATCGGTGCCTGCGGCGCCTGCACCGTCCATCTCGACGGCGAAGCCG
CGCGCTCATGCGTGCTGCCGGCCGCGAGCGTCGCGGGCCGCTCGGTCACGACGATCGAAGGGCTGTCGCACGATCGCTCG
CACCCGGTGCAGCGCGCGTGGATCGAGAAGGACGTGCCGCAGTGCGGCTACTGCCAGTCCGGGATGGTGATGGCCACCGC
CGCGCTGCTCGCGCGGCATCGCAAGCCGACCGACGCGCAGATCGACCAGGCCGTCACGAACCTGTGCCGCTGCGCGACCT
ATCAACGCATTCGTGAGGCGATCCATGTCGCGGCCGGCTGA

Upstream 100 bases:

>100_bases
AGGTCATTGGCGCGGCTTTTTGCGCCGCCAAGAATCTCTGTCAAGCATCGCCGCCATCCGCCGGATGACGCACCGGCGAT
GCGCGACAGGGAGACAGACG

Downstream 100 bases:

>100_bases
CGCGGGGCGGGCGCGGCATGCGCCGAACGCGTCCCGGCGCGTGTTCCTGAAAGGCGGCGTCGCGCTGGCGGGTAGCCTGC
TGCTGCCGCTCGCGATCGGC

Product: 2Fe-2S iron-sulfur cluster binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MRFTLNGQPFDFDGDPDTPLLWVIRDSARLTGTKYGCGIGACGACTVHLDGEAARSCVLPAASVAGRSVTTIEGLSHDRS
HPVQRAWIEKDVPQCGYCQSGMVMATAALLARHRKPTDAQIDQAVTNLCRCATYQRIREAIHVAAG

Sequences:

>Translated_146_residues
MRFTLNGQPFDFDGDPDTPLLWVIRDSARLTGTKYGCGIGACGACTVHLDGEAARSCVLPAASVAGRSVTTIEGLSHDRS
HPVQRAWIEKDVPQCGYCQSGMVMATAALLARHRKPTDAQIDQAVTNLCRCATYQRIREAIHVAAG
>Mature_146_residues
MRFTLNGQPFDFDGDPDTPLLWVIRDSARLTGTKYGCGIGACGACTVHLDGEAARSCVLPAASVAGRSVTTIEGLSHDRS
HPVQRAWIEKDVPQCGYCQSGMVMATAALLARHRKPTDAQIDQAVTNLCRCATYQRIREAIHVAAG

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI71773480, Length=152, Percent_Identity=39.4736842105263, Blast_Score=78, Evalue=3e-15,
Organism=Homo sapiens, GI91823271, Length=157, Percent_Identity=37.5796178343949, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI1789232, Length=143, Percent_Identity=42.6573426573427, Blast_Score=103, Evalue=4e-24,
Organism=Escherichia coli, GI1786480, Length=163, Percent_Identity=36.8098159509202, Blast_Score=98, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17540638, Length=156, Percent_Identity=41.025641025641, Blast_Score=112, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17539860, Length=153, Percent_Identity=37.9084967320261, Blast_Score=102, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI32566215, Length=153, Percent_Identity=36.6013071895425, Blast_Score=99, Evalue=6e-22,
Organism=Drosophila melanogaster, GI17737937, Length=151, Percent_Identity=39.0728476821192, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24647197, Length=158, Percent_Identity=34.8101265822785, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24647195, Length=158, Percent_Identity=34.8101265822785, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24647201, Length=150, Percent_Identity=34.6666666666667, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24647199, Length=151, Percent_Identity=34.4370860927152, Blast_Score=83, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24647193, Length=157, Percent_Identity=33.7579617834395, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 15686; Mature: 15686

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
5.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFTLNGQPFDFDGDPDTPLLWVIRDSARLTGTKYGCGIGACGACTVHLDGEAARSCVLP
CEEECCCCCCCCCCCCCCCEEEEEECCCEECCCCCCCCCCCCCEEEEEECCHHHHHHHCC
AASVAGRSVTTIEGLSHDRSHPVQRAWIEKDVPQCGYCQSGMVMATAALLARHRKPTDAQ
HHHHCCCCEEEECCCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHH
IDQAVTNLCRCATYQRIREAIHVAAG
HHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRFTLNGQPFDFDGDPDTPLLWVIRDSARLTGTKYGCGIGACGACTVHLDGEAARSCVLP
CEEECCCCCCCCCCCCCCCEEEEEECCCEECCCCCCCCCCCCCEEEEEECCHHHHHHHCC
AASVAGRSVTTIEGLSHDRSHPVQRAWIEKDVPQCGYCQSGMVMATAALLARHRKPTDAQ
HHHHCCCCEEEECCCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHH
IDQAVTNLCRCATYQRIREAIHVAAG
HHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]